Clinical trials: Conditioning Therapy
Obsessive-Compulsive Disorder
Internet-delivered CBT for Adolescents With OCD: A Randomized Controlled Study
The effect of Internet-delivered Cognitive Behavior Therapy (ICBT) on adolescents (12 to 17 years) with Obsessive-Compulsive Disorder is studied. Participants are randomized to either ICBT or a no-treatment condition.
- Trial name
- BiPOCD (NCT02191631)
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 67 people
- Sponsor
- Karolinska Institutet
Cancer, Psychological Distress
Support and Healing Intervention for Adolescents With a Parent Diagnosed With Cancer (SHINE)
e purpose of this study is to develop and evaluate SHINE (Support and Healing Intervention for Navigating Parental Cancer Experiences), a family-centered program designed to support adolescents whose parent has been diagnosed…
- Conditions
- Cancer, Psychological Distress, Adaptation, Psychological
- Trial name
- SHINE (NCT07751185)
- Testing
- SHINE Psychosocial Intervention, Usual Supportive Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas Southwestern Medical Center
Obesity, Overweight
Addressing Anxiety and Stress for Healthier Eating in Teens
Project ASSET will explore the preliminary efficacy of interpersonal therapy, when compared with cognitive behavioral therapy, for reducing anxiety symptoms, preventing excess weight gain, and reducing cardio-metabolic risk in…
- Conditions
- Obesity, Overweight, Anxiety, Mental Disorders
- Trial name
- ASSET (NCT05038033)
- Testing
- Interpersonal Psychotherapy (IPT), Cognitive Behavioral Theory (CBT)
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Metis Foundation
Depression / Major Depressive Disorder, Bipolar Disorder (BD)
Identifying Biomarkers of Response to Digital Interventions for Mood Disorders
The proposed study will be a single-arm pragmatic clinical trial examining the feasibility of online CBT within the CAN-BIND sites and the biomarkers of treatment response to online CBT for mood disorders.
- Trial name
- CAN-BIND-iCBT (NCT07783633)
- Testing
- Online Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Centre for Addiction and Mental Health
Disruptive Mood Dysregulation Disorder
Adapting DBT for Children With DMDD: Pilot RCT
This study examines feasibility and preliminary efficacy of Dialectical Behavior Therapy adapted to children (DBT-C). DBT-C as compared to treatment-as-usual (TAU) is hypothesized to have lower drop-out rate, and higher treatment…
- Trial name
- NCT01862549
- Testing
- Dialectical Behavior Therapy for children, Treatment as Usual
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Weill Medical College of Cornell University
Congenital Heart Disease in Children, RSV
Adherence to Palivizumab Prophylaxis
The goal of this clinical trial is to analyze implications of two alternative nudge-interventions to increase adherence to palivizumab prophylaxis in children with congenital heart disease.
- Trial name
- NCT05778240
- Testing
- Phone call, Text message, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 229 people
- Sponsor
- Kosuyolu Heart Hospital
Autism Spectrum Disorder
Parent-mediated Developmental Behavioral Intervention
This study explores the effectiveness of two intervention programs: "Long-distance developmental behavioral intervention" and "developmental behavioral interventions" for children with autism spectrum disorder or multiple…
- Trial name
- PDBI (NCT03812068)
- Testing
- Long-distance developmental behavioral intervention, Developmental behavioral intervention
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Psychotic Disorders
VR-assisted CBT for Adolescents With Psychosis
Psychotic disorders typically emerge during late adolescence or early adulthood. Patients, who are diagnosed with a psychotic disorder before turning 18 years, are defined as early onset psychosis patients (EOP).
- Trial name
- NCT04586868
- Testing
- An intervention development study, A randomized feasibility study, A single-case study
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Moyamoya Disease, Pediatric
Safety and Efficacy of RIC in Pediatric Moyamoya Disease Patients Treated With Revascularization Therapy
Revascularization surgery has been the standard treatment to prevent ischemic stroke in pediatric Moyamoya disease (MMD) patients with ischemic symptoms.
- Trial name
- RIC-PMD (NCT03546309)
- Testing
- RIC group, Medication group
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Capital Medical University
Risk Reduction
Children Education and Cardiovascular Risk Reduction in Their Parents
This study aims to evaluate if a multidisciplinary educational program in primary cardiovascular prevention for children could improve the Framingham Score index of their parents after one year.
- Trial name
- CETICARP (NCT01416545)
- Testing
- Educational program in cardiovascular prevention, Lifestyle counseling
- Where
- Brazil
- Volunteers
- 520 people
- Sponsor
- University of Sao Paulo
Premature Birth
Early Behavioral Intervention for Preterm Infants
The purpose of this study is to determine the effects of Family Nurture Intervention in preschool aged children between 2.5 and 4.5 years of age who were born prematurely and exhibit developmental deficits.
- Trial name
- EBI (NCT02379130)
- Testing
- Family Nurture Intervention, Play and Nutrition Intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy
Cognitive Behavioral Group Treatment for Obsessive-compulsive Disorder in Youth
Obsessive-compulsive disorder (OCD) is a debilitating disorder characterized by unwanted intrusive thoughts and disrupting repetitive rituals.
- Conditions
- Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy, Adolescent
- Trial name
- NCT04891367
- Testing
- Cognitive behavioral therapy
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Aarhus University Hospital
Anxiety Disorders
School-based Treatment of Anxiety Research Study (STARS)
This research is being done to compare two types of talk therapy to see which is most effective in helping school children with anxiety disorders.
- Trial name
- STARS (NCT01761396)
- Testing
- CBT, UC
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- UConn Health
Hematologic Neoplasm, HIV Infection
Stem Cell (Modified Bone Marrow) Transplantation in HIV-Infected Patients With Blood Cancer
This study will investigate the safety and effectiveness of a new stem cell transplant procedure to treat acute or chronic leukemia, multiple myeloma, myelodysplastic syndrome, Hodgkin's and non-Hodgkin's lymphoma in HIV-infected…
- Trial name
- NCT00005785
- Testing
- GCSF Mobilized Allogeneic PBSC Cultured w/Cytokines; Transduced w/RV
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Alcohol Abuse
Alcohol Early Intervention for Freshmen
Alcohol abuse among college students is a significant and long-standing public health issue. The transition into college is marked by substantial increases in alcohol abuse and problems, suggesting the importance of interventions…
- Trial name
- Transitions (NCT00852033)
- Testing
- Brief Motivational Intervention (BMI), Parent Based Intervention plus booster, Combined brief motivational intervention and parent based intervention plus boosters for both interventions
- Where
- United States
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia
Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer
This clinical trial studies the side effects and best dose of giving fludarabine and total-body irradiation (TBI) together followed by a donor stem cell transplant and cyclosporine and mycophenolate mofetil in treating human…
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission
- Trial name
- NCT00112593
- Testing
- fludarabine phosphate, total-body irradiation, peripheral blood stem cell transplantation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Fred Hutchinson Cancer Center
Substance-related Disorders, Alcohol-related Disorders
Specialized Substance Abuse Supervision (SSAS) Versus Non-SSAS Recidivism Rates Among Nebraska Felony Drug Offenders
This social science study hypothesizes that convicted felony drug offenders in Nebraska who participated in Specialized Substance Abuse Supervision (SSAS) as part of their probation or parole showed significantly better outcomes…
- Trial name
- SSAS (NCT00690352)
- Testing
- Specialized Substance Abuse Supervision (SSAS)
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Nebraska
ADHD
Impact of Parental Emotion Regulation on the Treatment of ADHD
Aim: To examine if parental emotion regulation (ER) moderates the response to parent training interventions. H1: Reduced parental ER capacity will predict diminished efficacy for behavioral parent training to improve negative…
- Trial name
- PERS (NCT05299814)
- Testing
- Behavioral Parenting Intervention
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Milton S. Hershey Medical Center
Depressive Symptoms
Automated and Personalized Cognitive Behavioral Therapy
This study is designed to evaluate a novel online tool to deliver computerized Cognitive Behavioral Therapy (CBT). Participants will be randomized into three groups: experimental, active control, and waitlist.
- Trial name
- NCT03445598
- Testing
- Interactive and personalized CCBT, Feature-limited CCBT, Waitlist control
- Where
- India
- Volunteers
- 600 people
- Sponsor
- Indian Institute of Technology Kanpur
Psychotherapy Intervention Evaluation
iCBT for Children and Adolescents With Obsessive-compulsive Disorder II
Internet-based psychotherapy for children and adolescents with obsessive-compulsive symptoms and an age of 6 to 18 years. Sessions are verified with teleconferencing with an psychotherapist, children and their parents.
- Trial name
- NCT05037344
- Testing
- Cognitive-behavioral psychotherapy
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
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