Clinical trials: Conduction Block
Complete AV Block, Sick Sinus Syndrome
Left Ventricular Pacing to Avoid Cardiac Enlargement Study
In this study, the investigators will examine whether left ventricular pacing is superior to right ventricular apical pacing in preventing deterioration of left ventricular systolic function and cardiac remodeling in patients…
- Trial name
- LVPACE (NCT01302717)
- Testing
- LV pacing, RV pacing
- Where
- 2 sites in South Korea
- Sponsor
- Seoul National University Hospital
Transcatheter Aortic Valve Replacement
Prognostic Factors in NOP-LBBB After TAVI
The goal of this observational study is to find prognostic factors in patients with a new-onset persistent left bundle branch block (NOP-LBBB) after transcatheter aortic valve implantation (TAVI).
- Trial name
- ProgNOP-LBBB (NCT05654792)
- Testing
- Transcatheter aortic valve implantation
- Volunteers
- 230 people
- Sponsor
- Central Hospital, Nancy, France
Aortic Valve Stenosis, AV Block
Prospective Arm of Conduct - Edwards SAPIEN3 PPI Registry
There are procedure related risk factors for permanent pacemaker implantation (PPI) that can be identified and assessed in a prospective cohort of 300 patients at high risk for PPI Prospective, multicenter, European registry in…
- Conditions
- Aortic Valve Stenosis, AV Block, Bundle-Branch Block
- Trial name
- Conduct-pro (NCT03715894)
- Testing
- transcatheter valve implantation
- Where
- 5 sites in Germany, Netherlands and 1 more
- Volunteers
- 300 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Systemic Sclerosis, Cardiac Diseases
Development and Prevention of Severe Heart Disease in Systemic Sclerosis
Systemic sclerosis is an orphan, multiorgan disease affecting the connective tissue of the skin and all internal organs. Cardiac involvement, mainly characterised by small intramyocardial coronary artery involvement and…
- Conditions
- Systemic Sclerosis, Cardiac Diseases, Heart Block, Cardiac Arrhythmia
- Trial name
- NCT01829126
- Where
- 11 sites in France, Germany and 4 more
- Volunteers
- 765 people
- Sponsor
- Gabriele Valentini
Left Bundle-Branch Block, Aortic Stenosis
Study on Heart Block Risks Using Outcome-Based Modeling
This study developed a prediction model for high-grade atrioventricular block (AVB) and complete left bundle branch block (CLBBB) following transcatheter aortic valve replacement (TAVR) in Chinese patients with aortic stenosis…
- Trial name
- SAVIOR (NCT07065123)
- Testing
- The population undergoing TAVR for aortic valve stenosis with outcomes of permanent pacemaker implantation and complete left bundle branch block after surgery
- Volunteers
- 112 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Heart Failure，Congestive, Left Ventricular Dysfunction
LV Endocardial CRT for Patients With Intermediate QRS Width
This pilot study is designed as a multi-centre cohort study determining the degree of LV reverse remodeling in patients with intermediate QRS widths (120-149ms) who undergo CRT implant with transseptal LV leads, and comparing to…
- Conditions
- Heart Failure，Congestive, Left Ventricular Dysfunction, Left Bundle-Branch Block
- Trial name
- EndoCRT (NCT03573427)
- Testing
- Trans-atrial septal placement LV lead for CRT
- Where
- 8 sites in Canada
- Sponsor
- Jaimie Manlucu
Myocardial Infarction, Coronary Artery Disease
Arrhythmias in Post-Myocardial Infarction Patients
Patients are screened for significant arrhythmias and other possibly significant ECG-patterns directly after discharge and two weeks after myocardial infarction using wearable devices.
- Conditions
- Myocardial Infarction, Coronary Artery Disease, Arrythmia, ECG Electrical Alternans
- Trial name
- NCT03231826
- Where
- Finland
- Volunteers
- 445 people
- Sponsor
- Tampere University
Sinus Bradycardia, Atrioventricular Block
Analysis of Adenosine on Sinus and Atrioventricular Nodal Conduction in the Pediatric Transplanted Heart
Heart transplants save the lives of nearly 500 children in heart failure per year. Columbia is one of the largest pediatric heart transplant centers in the world, averaging 25 transplants per year, and providing ongoing care to…
- Trial name
- NCT02462941
- Testing
- Adenosine, Cardiac catheterization
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Columbia University
Heart Block, Heart Block Complete
Effect of Site of Right Ventricular (RV) Pacing on RV Function, Left Ventricular (LV) Dyssynchrony and Contraction Efficiency
To evaluate RV systolic function and LV mechanical dyssynchrony and function in different lead position in the RV during permanent pacemaker implantation by using speckle tracking echocardiography (STE) and 3D volumetric ejection…
- Conditions
- Heart Block, Heart Block Complete, Systolic Function
- Trial name
- NCT06636851
- Testing
- Pacemaker and defibrillator
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- South Valley University
Atrial Fibrillation, Bradycardia
Prospective Registry of Pacemaker Patients Concerning Percentage of Right Ventricular Pacing, LVEF and NYHA Class
This registry is a data collection on patients who are implanted for more than 6 months with a pacemaker. Frequency and distribution of right ventricular pacing, NYHA class and left ventricular ejection fraction shall be…
- Conditions
- Atrial Fibrillation, Bradycardia, Heart Block, Sick Sinus Syndrome
- Trial name
- NCT00292539
- Testing
- Any pacemaker with right ventricular pacing option
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Guidant Corporation
Aortic Stenosis, Transcatheter Aortic Valve Replacement
Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction System
This is a prospective observational study, the purpose of which is to: 1. Characterize response of the AV conduction system to TAVR with various prostheses by recording continuous His bundle electrograms during valve placement.
- Conditions
- Aortic Stenosis, Transcatheter Aortic Valve Replacement, Heart Block
- Trial name
- TAVR-HBE (NCT04982406)
- Testing
- Transcatheter aortic valve replacement
- Where
- United States
- Volunteers
- 409 people
- Sponsor
- Beth Israel Deaconess Medical Center
Bradycardia, Conduction Block, Atrioventricular
LLL vs. SDL for LBBP: A Non-inferiority RCT
Left Bundle Branch Pacing (LBBP) has emerged as one of the most commonly used physiological pacing modalities in clinical practice.
- Trial name
- NCT07378124
- Testing
- SDL implantation, LLL implantation
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Ningbo No.2 Hospital
Heart Block After Surgery
Rhythm Disturbances After Ventricular Septal Defects
We would like to conduct a retrospective chart review examining the incidence of surgical heart block in children treated in the Cardiac Service Line at Children's Healthcare of Atlanta.
- Trial name
- NCT00208624
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
AVB - Atrioventricular Block
Left Bundle Branch Pacing Versus Right Ventricular Pacing in Patients With Atrioventricular Block
Although emerging evidence demonstrated that left bundle branch pacing (LBBP) is a promising alternative for patients with either a bradycardia or a heart failure pacing indication.
- Trial name
- NCT05722379
- Testing
- left bundle branch pacing (LBBP), Right ventricular pacing (RVP)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- West China Hospital