Clinical trials: Conduction Disorder
Cardiac Arrhythmias, Accessory Pathway
Cryotherapy Versus Radiofrequency Ablation for Treatment of Para-hisian Accessory Pathways
A randomized pilot study to evaluate safety and efficacy endpoints for treatment of para-hisian accessory pathways according to two different strategies of lesion formation.
- Conditions
- Cardiac Arrhythmias, Accessory Pathway, Wolf Parkinson White Syndrome
- Trial name
- NCT04361006
- Testing
- Radiofrequency (RF), Cryotherapy (CRYO)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Bradycardia, Tachycardia
Clinical Study to Confirm MRI Safety and Effectiveness Using St. Jude Medical (SJM) Cardiac Rhythm Management Systems
This is a clinical investigational plan (CIP) for the "Clinical Study to Confirm MRI Safety and Effectiveness Using SJM Cardiac Rhythm Management Systems (ASSURE MRI)".
- Trial name
- ASSUREMRI (NCT03012568)
- Testing
- SJM Implantable cardiac devices
- Where
- 3 sites in Australia, India
- Volunteers
- 119 people
- Sponsor
- Abbott Medical Devices
Supraventricular Tachycardia
Multicenter Study of Antiarrhythmic Medications for Treatment of Infants With Supraventricular Tachycardia
This is a randomized, double-blind, multi-centered study to compare 6 months of medical treatment with digoxin or propranolol in infants with SVT Background: SVT is the most common sustained arrhythmia of infancy.
- Trial name
- NCT00390546
- Testing
- Digoxin, Propranolol
- Where
- 14 sites in United States, Canada
- Volunteers
- 72 people
- Sponsor
- University of British Columbia
Cardiac Disease, Syncope
Second Study on Cardio-neuromodulation in Humans
Different approaches to cardio-neuroablation (CNA) to treat neurally mediated syncope, sinus node dysfunction, and functional atrioventricular block have been published.
- Conditions
- Cardiac Disease, Syncope, Syncope, Vasovagal, Sick Sinus Syndrome
- Trial name
- CardNMH2 (NCT02954666)
- Testing
- radio-frequency ablation
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Imelda Hospital, Bonheiden
Ventricular Arrythmia
China Inherited Ventricular Arrhythmias Registry
This is an observational, prospective, multi-center registry, aiming at building a risk stratification for malignant inherited ventricular arrhythmias, including Brugada syndrome(Brs)、Long QT syndrome(LQTS)、Short QT…
- Trial name
- NCT03880708
- Where
- China
- Volunteers
- 500 people
- Sponsor
- China National Center for Cardiovascular Diseases
Diabetic Neuropathies
Effect of Neurodynamic Mobilization Techniques in Patients With Diabetic Neuropathy
Neurodynamic mobilization Techniques and Selected Physical program used as a treatment for diabetic neuropathy patients and assessed by nerve condition study and function outcome.
- Trial name
- NCT05628168
- Testing
- Neurodynamic Mobilization Techniques, Selected Physical Therapy Program
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- October 6 University
Coronary Artery Spasm, Hypertension
The Prevalence of Coronary Spasm in Hypertensive Patients Treated With Antihypertensive Medication
Autonomic nerve function is involved in both blood pressure (BP) regulation and the pathogenesis of coronary artery spasm(CAS), but few studies have been published about the relationship between CAS and effect of BP lowering…
- Trial name
- NCT01882790
- Where
- 3 sites in South Korea
- Volunteers
- 1,933 people
- Sponsor
- Korea University
Ventricular Tachycardia, Ventricular Fibrillation
Post-marketing Registration Study of Nifekalant Hydrochloride (NIF) Injection
Retrospective and Prospective single arm, observational study to evaluate efficacy and safety of NIF in the treatment of ventricular tachycardia and ventricular fibrillation.
- Trial name
- NCT03853369
- Testing
- Nifekalant hydrochloride
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Sichuan Baili Pharmaceutical Co., Ltd.
Heart Failure, Cardiomyopathies
The Multicenter Cardiology Monitoring Platform Registry
The multicenter Cardiology Monitoring Platform registry (mCMP-registry) is a prospective observational registry including multi-omics (diagnostic) measurements performed as part of routine clinical care, bio-banking (optional)…
- Conditions
- Heart Failure, Cardiomyopathies, Atrial Fibrillation, Ventricular Arrythmia
- Trial name
- mCMPregistry (NCT04976348)
- Where
- Netherlands
- Volunteers
- 40,000 people
- Sponsor
- Maastricht University Medical Center
Ventricular Arrhythmia, Tachycardia
Enlighten Study: The EV-ICD Post Approval Registry
Medtronic is sponsoring Enlighten: The EV-ICD Post Approval Registry, to further confirm safety and effectiveness of EV-ICD in routine clinical practice, following commercial release of EV-ICD devices.
- Trial name
- NCT06048731
- Testing
- Defibrillation using EV-ICD
- Where
- 130 sites in United States, Austria and 22 more
- Volunteers
- 1,000 people
- Sponsor
- Medtronic
Supraventricular Tachycardia
Evaluation of the Pharmacokinetic Profile, Pharmacodynamic Effects, Acceptability and Tolerability of an Oral Amiodarone Solution of 15 mg / mL in Children With Supra Ventricular Tachycardia
The supra ventricular tachycardia is the most common symptomatic arrhythmia in pediatrics. Amiodarone is an antiarrhythmic drug used in this indication.
- Trial name
- Enteramio (NCT03153072)
- Testing
- Assess the absorption of oral amiodarone
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Diabetes Mellitus Type I, Diabetic Peripheral Neuropathy
Prevalence of Peripheral Neuropathy in Children and Adolescents With Type I Diabetes Mellitus: a Prospective Study
Diabetes mellitus type I is an increasing burden for more and younger children. Therapy should avoid long-term complications as macrovascular diseases and diabetic nephropathy, retinopathy and diabetic neuropathy (DN).
- Conditions
- Diabetes Mellitus Type I, Diabetic Peripheral Neuropathy, Nerve Conduction Study Not Performed
- Trial name
- NCT01512030
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Landeskrankenhaus Feldkirch
Hearing Loss, Conductive, Hearing Loss, Unilateral
Adhear Bone Conduction System
The purpose of this research study is to learn about the hearing outcomes of adult and pediatric patients who are treated with or are candidates for bone conductive devices (also termed "BAHA").
- Trial name
- NCT03533686
- Testing
- Adhear Bone Conduction System, Bone anchored hearing aid (BAHA)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Miami
ECG Monitoring
Biomedical Shirt-based ECG Monitoring
Cardiovascular diseases (CVD) are associated with high healthcare costs, as well as are a leading cause of mortality and hospitalizations.
- Trial name
- ECG-shirt (NCT03068169)
- Where
- 3 sites in Poland
- Volunteers
- 220 people
- Sponsor
- Medical University of Warsaw
Arrhythmias, Cardiac, Heart Block
Holter Versus Zio Patch Electrocardiographic Monitoring in Children
This prospective study aims to compare the diagnostic yield, or ability to detect an arrhythmia, of the traditional Holter monitor versus the novel Zio patch monitor in pediatric patients referred for ambulatory…
- Trial name
- NCT03309956
- Testing
- Holter Monitor, Zio Patch
- Where
- United States
- Volunteers
- 247 people
- Sponsor
- Columbia University
Paroxysmal Supraventricular Tachycardia
The NODE-202 Study (Study of Etripamil Nasal Spray in Pediatric Patients)
NODE-202 is a Phase 2, multicenter, multinational, single dose, open-label, 2-part, sequential design study in pediatric patients with an established diagnosis of paroxysmal supraventricular tachycardia (PSVT) presenting with a…
- Trial name
- NCT05763953
- Testing
- Etripamil NS
- Where
- 10 sites in United States, Canada and 2 more
- Volunteers
- 60 people
- Sponsor
- Milestone Pharmaceuticals Inc.
Tachycardia, Hypertension
To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU.
The goal of this clinical trial is to to observe the haemodynamic parameters including Heart Rate Blood pressure Respiratory rate and Oxygen Saturation with or without giving reversal agent on extubation in patients receiving…
- Conditions
- Tachycardia, Hypertension, Hypoxia, Hyperventilation
- Trial name
- NCT07097441
- Testing
- neostigmine (reversal agent)
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Heart Block, Bradycardia
iPod and Other MP3 Players on ICDs and Pacemakers in Children
Unlike phones, which are commonly held to the ear, music is now available via portable MP3 players and they can be held almost anywhere.
- Conditions
- Heart Block, Bradycardia, Tachycardia, Arrhythmia
- Trial name
- NCT00542854
- Testing
- MP3
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Hearing Impaired Children, Hearing Impairment, Conductive
Single-stage Surgery Using the BI300 Implant
Over the last few decades, the classical two-stage surgical procedure for inserting bone-anchored hearing implants (BAHIs) has been modified in adults into a single-stage procedure.
- Trial name
- NCT04038216
- Testing
- Single-stage surgery, Two-stage surgery
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Radboud University Medical Center
Long QT Syndrome
The Canadian National Long QT Syndrome Registry
The NLQTS Research Network team aims to build a Canadian collaboration of dedicated investigators that will create a new paradigm in the modern investigation of patients with LQTS and in the description of a new disease modifier.
- Trial name
- LQTSREG (NCT02425189)
- Where
- Canada
- Volunteers
- 1,051 people
- Sponsor
- Andrew Krahn