Clinical trials: Congenital Heart Defect
Congenital Heart Disease
The Role of Tranexamic Acid in Reducing Blood Transfusion Requirements After Cardiopulmonary Bypass in Neonates
This is an observational, prospective study to evaluate the role of tranexamic acid in reducing blood transfusion in neonates undergoing cardiopulmonary bypass.
- Trial name
- NCT01914211
- Testing
- Tranexamic Acid, Acute Normovolemic Hemodilution
- Where
- United States
- Sponsor
- Aymen N Naguib
Acquired Bleeding Disorder, Cardiac Surgery Requiring Cardiopulmonary Bypass
Activated Recombinant Human Factor VII Following Cardiac Bypass Surgery for Paediatric Congenital Heart Disease
This trial is conducted in Oceania. The aim of this trial is to investigate the efficacy of activated recombinant human factor VII and standard treatment compared with standard haemostatic replacement therapy in cardiopulmonary…
- Trial name
- NCT01562574
- Testing
- activated recombinant human factor VII
- Where
- Australia
- Volunteers
- 82 people
- Sponsor
- Novo Nordisk A/S
General Anesthesia, Dexmedetomidine
General Anesthesia Versus Sedation By Dexmedetomidine and Ketamine With Local Infiltration for Percutaneous Transcatheter Closure of Atrial Septal Defect in Pediatric Patients
The aim of the present study is to compare between general anesthesia versus sedation with dexmedetomidine and ketamine with local infilteration at the catheter insertion site in pediatric patients undergoing transcutaneous…
- Conditions
- General Anesthesia, Dexmedetomidine, Ketamine, Local Infiltration
- Trial name
- NCT06431178
- Testing
- General Anesthesia, Local anesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Cardiac Catheterization
Acupressure's Impact on Pain and Physiological Parameters in Infants Undergoing Cardiac Catheterization
Acupressure, one of the traditional Chinese medicine practices dating back approximately 5,000 years, is a mind-body technique that can be independently applied by nurses.
- Trial name
- NCT06727526
- Testing
- Acupressure
- Volunteers
- 35 people
- Sponsor
- Baskent University
Heart Failure, Dilated Cardiomyopathy
Follow-up Safety Trial in Children With Chronic Heart Failure Therapy Receiving Orodispersible Minitablets of Enalapril
Paediatric long-term safety follow-up clinical trial in maximum 100 children with heart failure due to dilated cardiomyopathy or congenital heart disease, from 1 day to less than 12 years of age at recruitment into the preceding…
- Conditions
- Heart Failure, Dilated Cardiomyopathy, Congenital Heart Disease
- Trial name
- LENA-WP10 (NCT02654678)
- Testing
- Enalapril Orodispersible Minitablet
- Where
- 6 sites in Austria, Hungary and 3 more
- Volunteers
- 100 people
- Sponsor
- Ethicare GmbH
Congenital Heart Disease, Child Development
A Parent-child Yoga Intervention for Reducing Attention Deficits in Children with Congenital Heart Disease: a Feasibility Study
The proposed study aims to determine the feasibility of the procedures for a future full randomized controlled trial (RCT), which will test the efficacy of a parent-child yoga intervention in reducing attention deficits in…
- Conditions
- Congenital Heart Disease, Child Development, Neurodevelopmental Disorders, Parents
- Trial name
- NCT05997680
- Testing
- Parent-child yoga
- Where
- 2 sites in Canada
- Volunteers
- 24 people
- Sponsor
- Anne Gallagher
Congenital Heart Disease
Acute Effects of the Prostaglandin (Alprostadil) on Cerebral and Pulmonary Flow
The second stage operation towards single ventricle palliation is 'bidirectional cavopulmonary connection' (BCPC). The superior vena cava is connected to the pulmonary artery, diverting 'blue' blood from the upper body (including…
- Trial name
- Alprostadil (NCT04054115)
- Testing
- Alprostadil 5 MCG Injection
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- The Hospital for Sick Children
Growth Failure, Congenital Heart Disease
A Study to Evaluate the Effects of a New Formula on the Growth, Safety and Tolerance of Infants With Growth Failure
This study is a prospective, open-label, multi-site, growth, safety and tolerance study to evaluate a NF (New Formula). A minimum of 45 evaluable infants with confirmed growth failure will be enrolled.
- Trial name
- NCT03563391
- Testing
- New Infant Formula
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Nutricia North America