Clinical trials: Constipation
Constipation
Hypnosis for Children Undergoing Anorectal Manometry
Partially blinded randomized controlled trial investigating the effect of a brief session of hypnosis prior to anorectal manometry in children
- Trial name
- NCT04471857
- Testing
- Hypnosis
- Volunteers
- 34 people
- Sponsor
- Nationwide Children's Hospital
Chronic Constipation
An Open Single Centre Study To Assess Treatment of Chronic Constipation in Children
The purpose of this study was to evaluate the safety and efficacy of Movicol in the treatment of chronic constipation in children.
- Trial name
- NCT00403897
- Testing
- Polyethylene glycol 3350 Na bicarbonate NaCl KCl
- Where
- Australia
- Volunteers
- 81 people
- Sponsor
- Norgine
Functional Constipation in Children
Constipation Fiber Trial
This study examines the effects of dietary fiber in the treatment of functional childhood constipation.
- Trial name
- NCT02193997
- Testing
- Fiber
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Warren Bishop
Constipation, Childhood ALL
PTNS and PFR in the Treatment of Childhood Constipation
Constipation is the most common complaint in childhood, affecting an estimated 20% of children globally. At present, the treatment of children's constipation is full of challenges, and treatment methods are diverse.
- Conditions
- Constipation, Childhood ALL, Pelvic Floor Disorders
- Trial name
- NCT05059756
- Testing
- PTNS
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shengjing Hospital
Colonic Motility Index, Constipation
Effect of Octreotide on the Colonic Motility in Pediatric Patients
The research study is designed to test how a medication called octreotide affects the motility (contraction or squeezing) of the colon (large intestine).
- Trial name
- NCT01917773
- Testing
- Octreotide, Bisacodyl
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Indiana University
Encopresis
Internet-based Treatment of Early Childhood Fecal Incontinence
Encopresis, also known as fecal incontinence, is the voluntary or involuntary passage of stools causing soiling of clothes by a child over 4 years of age.
- Trial name
- NCT00067769
- Testing
- Internet-based intervention UCanPoopToo, treatment as usual
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Hirschprung's Disease, Constipation
Comparative Research Between Swenson and Soave Operations for Pediatric Patients Who Have Hirschsprung Disease
Hirschsprung's disease is characterized by a lack of enteric nervous system ganglion cells (aganglionosis) in a variable extent of distal bowel.
- Conditions
- Hirschprung's Disease, Constipation, RECTUM
- Trial name
- NCT07410286
- Testing
- Swenson operation includes resection of the aganglionic segment and anastomosis with full thickness layer above the dentate., Soave procedure: includes resection of the aganglionic segment and anastomosis with submucosal thickness layer above the dentate.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ahmed Aouf
Infantile Colics, Constipation
Randomized, Blinded, Placebo-Controlled Evaluation of BioAmicus Complete
This is a randomized, single-blind, placebo-controlled study to evaluate the efficacy of the dietary supplement BioAmicus Complete (oral drops; a mixture of 10 strains of lacto- and bifidobacteria) in managing functional…
- Conditions
- Infantile Colics, Constipation, Infantile Diarrhea, Atopic Dermatitis
- Trial name
- NCT07444008
- Testing
- BioAmicus Complete
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- NovoNatum Ltd
Irritable Bowel Syndrome With Constipation (IBS-C)
Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C
Open-label long-term safety study of tenapanor in pediatric patients with IBS-C.
- Trial name
- NCT05905926
- Testing
- Tenapanor
- Where
- 27 sites in United States
- Volunteers
- 150 people
- Sponsor
- Ardelyx
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD)
Indiana University Gastrointestinal Motility Diagnosis Registry
Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions.
- Conditions
- Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD), Gastroparesis, Functional Vomiting
- Trial name
- NCT04506593
- Testing
- no intervention
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Indiana University
Autism Spectrum Disorder, Gastrointestinal Symptoms
Combination Probiotic: BB-12 With LGG (Different Doses) in Treating Children With Autism Spectrum Disorder
This protocol is a blinded randomized controlled study of the effects of BB-12 with LGG at different doses in 70 healthy children with autism spectrum disorders at lower and higher doses over an 56-day period and a 28- day…
- Trial name
- NCT03514784
- Testing
- BB-12 with LGG (Higher Dose), BB-12 with LGG (Lower Dose)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Autism, Autistic Disorder
Safety and Efficacy Study in the Treatment of Intestinal Problems Associated With Autism
The purpose of this study is to determine if human immunoglobulin given by mouth twice a day is effective in treating the persistent gastrointestinal (GI) problems such as diarrhea, constipation, abdominal pain, and bloating, in…
- Conditions
- Autism, Autistic Disorder, Child Development Disorders, Pervasive, Gastrointestinal Diseases
- Trial name
- NCT00110708
- Testing
- Oralgam (human immunoglobulin)
- Where
- 22 sites in United States
- Volunteers
- 120 people
- Sponsor
- PediaMed Pharmaceuticals
Autistic Disorder, Constipation
Impact of Improving Gastrointestinal Symptoms on Autism Symptoms and Oxidative Stress
The clinical manifestation of autism spectrum disorder (ASD) is complex, with medical and mental health disruptions that occur with the three core behavioral criteria used for diagnosis (social behavior, communication, restricted…
- Conditions
- Autistic Disorder, Constipation, Gastrointestinal Diseases
- Trial name
- NCT02442115
- Testing
- Treatment of Functional Constipation by
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Los Angeles
Constipation
PolyethyleneGlycol3350 Laxative vs Placebo in Constipated Children
Assess the safety and efficacy of polyethyleneglycol3350 laxative as compared to placebo therapy in pediatric patients with a history of constipation.
- Trial name
- NCT00153114
- Testing
- polyethyleneglycol3350
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Braintree Laboratories
Constipation
Maintenance Treatment for Children With Constipation
Constipation is a common problem among children. The majority of children suffering from constipation have no underlying disease.
- Trial name
- NCT01566409
- Testing
- Polyethylene glycol 3350
- Where
- Denmark
- Volunteers
- 115 people
- Sponsor
- Line Modin
Constipation - Functional
Breath Gases, Gut Flora, and Immunity in Children With Constipation
Constipation is a common problem in children that can affect their daily life, school performance, and social activities. Researchers have found that the bacteria living in our intestines (called "gut microbiome") may play an…
- Trial name
- NCT07797491
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Chronic Functional Constipation
Quality of Life in Children and Adolescents With Chronic Functional Constipation: Educational Action Effects
The purpose of this study is to determine if the quality of life in children and adolescents diagnosed with chronic functional constipation improves after educational activity in focus group composed by these patients' mothers.
- Trial name
- NCT01901445
- Testing
- Educational action with focal group
- Where
- Brazil
- Volunteers
- 11 people
- Sponsor
- Universidade Federal de Pernambuco
Constipation - Functional
Lubiprostone for Children With Constipation
This study is for children with constipation. Children who completed 3 months of treatment in the earlier study (NCT02042183): were invited to participate will receive lubiprostone for 9 more months will see if lubiprostone…
- Trial name
- NCT02138136
- Testing
- Lubiprostone
- Where
- 85 sites in United States, Belgium and 5 more
- Volunteers
- 419 people
- Sponsor
- Sucampo Pharma Americas, LLC
Functional Constipation
Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation
The purpose of this study is to evaluate the dose response, safety, and efficacy of linaclotide when compared with placebo in pediatric participants, 2 to 5 years of age, with Functional Constipation.
- Trial name
- NCT04110145
- Testing
- Linaclotide
- Where
- 18 sites in United States
- Volunteers
- 35 people
- Sponsor
- Allergan
Constipation
A Study to Compare the Effect of Transipeg 2.95 g or Forlax Junior 4 g in Children With Constipation
The study design combines a long-term safety and a dose range determination objective. The first 8 weeks of the study were primarily intended for the dose range determination, while the later visits were used for the comparison…
- Trial name
- NCT01810653
- Testing
- Macrogol (Transipeg, BAY81-8430), Macrogol (Forlax)
- Where
- 4 sites in Netherlands
- Volunteers
- 97 people
- Sponsor
- Bayer