Clinical trials: Constipation - Functional
Functional Constipation, Irritable Bowel Syndrome With Constipation
Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)
The objective of LIN-MD-64 is to evaluate the safety and efficacy of 12 weeks of linaclotide therapy (72 μg daily) in comparison with placebo in pediatric participants, 6 to 17 years of age, who fulfill modified Rome III Criteria…
- Trial name
- NCT04026113
- Testing
- Linaclotide
- Where
- 115 sites in United States, Belgium and 12 more
- Volunteers
- 438 people
- Sponsor
- AbbVie
Constipation - Functional
Adherence/Outcomes After Use of Constipation Action Plan
Adherence to recommendations for treatment of chronic constipation in pediatric population is often poor. This study is attempting to improve adherence, and outcomes, by implementing a trial of a constipation action plan plus…
- Trial name
- NCT03821532
- Testing
- Constipation Action Plan
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Constipation
Effects of Probiotics (BioKid LR - Contains Nine Different Species of Probiotics Bacteria Including L. Reuteri) in Children With Functional Constipation
The goal of this clinical trial is to evaluate whether a probiotic supplement, BioKid LR®, can help maintain normal bowel movements after stopping laxative treatment (PEG 3350) in children aged 6 months to 17 years with…
- Trial name
- NCT06959758
- Testing
- Probiotic Arm
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Ferass Abu Hanna
Functional Constipation
The Effect of Probiotics on Constipation, and Intestinal Microflora in Children With Functional Constipation
To compare the differences of fecal microflora between constipated and non-constipated healthy children, and evaluate the efficacy of probiotics in reducing symptoms of constipation and the influence of intestinal microflora in…
- Trial name
- NCT03054805
- Testing
- Magnesium Oxide, MIYAIRI-BM
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Constipation
GOS Prebiotic Effect in Children Constipation
Some prebiotics are useful for improving symptoms related to constipation, but clinical trials including infants and older children are scarce.
- Trial name
- NCT02183766
- Testing
- Galactooligosaccharide prebiotic, Maltodextrin
- Volunteers
- 20 people
- Sponsor
- University of Campinas, Brazil
Chronic Idiopathic Constipation, Functional Constipation
Botulinum Toxin Injection Versus Anal Myectomy in Management of Idiopathic Constipation
Chronic idiopathic constipation is most common cause of Constipation in childhood with numerous cases in Egypt. Numerous conservative measures were tried but many fail.
- Trial name
- NCT02361749
- Testing
- Botulinum Toxin, Anal Myectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Chronic Constipation
Physiotherapeutic Intervention in Children With Chronic Functional Constipation
The purpose of this study is to determine whether physiotherapy is effective in the treatment of the chronic functional constipation in children.
- Trial name
- NCT00906971
- Testing
- diaphragmatic breathing, isometric training of the abdominal muscles and abdominal massage
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Universidade Federal de Pernambuco
Constipation
Single Dose Pharmacokinetics of Prucalopride in Paediatric Subjects, With Functional Faecal Retention
The purpose of this study is characterize the pharmacokinetics of a single oral dose of 0.03 mg/kg prucalopride in paediatric subjects aged >= 4 to <= 12 years with functional faecal retention.
- Trial name
- NCT01674166
- Testing
- prucalopride
- Volunteers
- 38 people
- Sponsor
- Movetis
Functional Constipation, Fecal Impaction
Comparison of Efficacy & Tolerability Of PEG 4000 Versus PEG 3350+ Electrolytes for Pediatric Fecal Disimpaction
Childhood constipation is a common but serious gastrointestinal disorder prevalent worldwide. In 90-95% of children, it is of functional origin.
- Conditions
- Functional Constipation, Fecal Impaction, Constipation - Functional, Constipation Chronic Idiopathic
- Trial name
- NCT06349031
- Testing
- Administration of Polyethylene Glycol (PEG) 4000 as per treatment allocation to participants, Administration of Polyethylene Glycol (PEG) 3350 + Electrolyte as per treatment allocation to participants
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Institute of Medical Sciences and SUM Hospital
Physical Therapy in Pediatric Functional Constipation
Physical Therapy for Functional Constipation in Children
Children diagnosed with functional constipation are subjected to physical therapy combined with conventional treatment
- Trial name
- NCT06207721
- Testing
- Polyethylene Glycols, Physical therapy program
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Delta University for Science and Technology
Constipation - Functional
Evaluation of the Effectiveness of a Mobile Application in the Treatment of Children With Functional Constipation
This randomized, double-blind clinical trial evaluates the effectiveness of use of a mobile health application in supporting the treatment of functional constipation in children aged 4 to 18 years.
- Trial name
- NCT07025135
- Testing
- comparison between use of mobile app, Patient-caregiver dyad using printed recommendations
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Gdansk
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD)
Indiana University Gastrointestinal Motility Diagnosis Registry
Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions.
- Conditions
- Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD), Gastroparesis, Functional Vomiting
- Trial name
- NCT04506593
- Testing
- no intervention
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Indiana University
Mollii Suit, Cerebral Palsy
Effects of Mollii Suit in Children With Non-Ambule Cerebral Palsy
The aim of our study is to examine the effectiveness of the Mollii Suit application on gross motor function, spasticity, postural control, upper extremity skills, selective motor control, daily living activities, quality of life…
- Trial name
- NCT06259864
- Testing
- EXOPULSE Mollii Suit method
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Kırıkkale University
Irritable Bowel Syndrome
Prevalence of Intestinal Parasitic Infections in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is common medical disorder and represent a group of diseases of the gastrointestinal tract that is characterized by chronic abdominal pain , bloating , passage of mucus or straining with bowel…
- Trial name
- NCT05830370
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Constipation - Functional, Pediatric
Comparison of Two Interventions in Children with Functional Constipation
The purpose of this study; to compare the effects of therapeutic motor control interventions and conventional treatment in children with functional constipation on symptoms, spinal posture and mobility and trunk muscles endurance.
- Trial name
- NCT05371678
- Testing
- Therapeutic motor control interventions, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Abant Izzet Baysal University
Irritable Bowel Syndrome With Constipation, Functional Constipation
Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C
LIN-MD-66 is a Phase 3 open-label study with 24 weeks (Functional Constipation participants) or 52 weeks (Irritable bowel syndrome with constipation participants) of linaclotide exposure that will enroll pediatric participants…
- Trial name
- NCT04166058
- Testing
- Irritable Bowel Syndrome with Constipation (IBS-C) participants (LIN-MD-63 and LIN-MD-64 completers), Functional Constipation (FC) participants (LIN-MD-62 and LIN-MD-64 completers)
- Where
- 72 sites in United States, Canada and 2 more
- Volunteers
- 381 people
- Sponsor
- AbbVie
Refractory Constipation, Fecal Incontinence in Children
The Role of Anorectal Manometry in Pediatric Chronic Refractory Constipation
This research protocol outlines a two-year descriptive cross-sectional study to investigate the role of high-resolution anorectal manometry (HRAM) in children aged 4-18 years with chronic refractory constipation.The study plans…
- Trial name
- NCT07291661
- Testing
- High resolution anorectal manometry using a multiuse water perfused catheter
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Assiut University
Functional Gastrointestinal Disorders
Evolution of Functional Gastrointestinal Disorders in Infants Fed With a New Infant Formula
This study aims to assess the evolution of functional gastrointestinal disorders (FGIDs) in infants fed with a new infant formula, using the Gastrointestinal (GI) and gastroesophageal reflux (GER) (GIGER) scale through an…
- Trial name
- NCT06488274
- Testing
- New infant formula
- Where
- 4 sites in France
- Volunteers
- 139 people
- Sponsor
- United Pharmaceuticals
Functional Constipation
A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide
Functional constipation (FC) is a common healthcare problem in children of all ages, potentially due to genetic predisposition, inadequate fiber and fluid intake, and immobility.
- Trial name
- NCT05760313
- Testing
- Linaclotide
- Where
- 38 sites in United States, Bulgaria and 5 more
- Volunteers
- 19 people
- Sponsor
- AbbVie
Functional Constipation
The Inside Study: Oligosaccharides Versus Placebo in Functional Constipation
In the present randomised double blind controlled study, the investigators will study the effects of oligosaccharides vs a placebo on the change in stool consistency and stool frequency in children with functional constipation.
- Trial name
- Inside (NCT04282551)
- Testing
- dietary intervention with oligosaccharides
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Wageningen University and Research