Clinical trials: Contrast Agent
Diagnostic Self Evaluation, Central Nervous System Diseases
Safety and Efficacy Evaluation of DOTAREM® in MRI of Central Nervous System (CNS) Lesions
The purpose of this study is to look at the safety (what are the side effects)and efficacy (how well does it work) of Dotarem® when used in taking images of the brain / spine.
- Trial name
- SENTIO (NCT01211873)
- Testing
- Dotarem (gadoterate meglumine), Magnevist (gadopentetate dimeglumine)
- Where
- 52 sites in United States, Argentina and 9 more
- Volunteers
- 416 people
- Sponsor
- Guerbet
Exertional Heat Illness, Hydration Status
Comparing Risk of Heat Illness Based on Peak Core Temps During Preseason Football Camp Across 3 Different Age Levels
To collect field data in professional, collegiate, and high school football players to determine how they respond physiologically to the rigors of preseason training environment.
- Trial name
- NCT01954537
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Trauma Abdomen
CEUS for Blunt Abdominal Trauma in Children
Children with blunt abdominal trauma often get a CT as the first line imaging to evaluate for intra-abdominal organ injury. CT scans have some downsides with regard to radiation exposure, costs, and need for transport.
- Trial name
- NCT03490929
- Testing
- Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Intravenous Powder for Suspension [LUMASON], contrast-enhanced ultrasound
- Where
- 2 sites in United States
- Volunteers
- 146 people
- Sponsor
- Children's Hospital of Philadelphia
Atherosclerosis
Comparison of Magnetic Resonance Angiography and Standard Angiography in Diagnosing Atherosclerosis
This study will evaluate ways to improve magnetic resonance angiography (MRA) for diagnosing atherosclerosis (hardening and narrowing of the arteries).
- Trial name
- NCT00001946
- Testing
- Magnetic resonance angiography
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Ventricular Arrythmias
The V-Tachogram:Decreasing Ventricular Arrythmias When Injecting Contrast in the Left Ventricle
The purpose of this study is to determine if increasing the linear rise rate of injection of x-ray contrast in the heart during left ventriculograms(part of a cardiac Catheterization procedure) will decrease the incidence of…
- Trial name
- NCT00288756
- Testing
- lv injection of contrast
- Where
- Canada
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Trillium Health Centre
Hypothyroidism
Iodinated Contrast Agents and Risk of Hypothyroidism in Young Children in the United States
This study will estimate the incidence of hypothyroidism in a pediatric population of children under age 4, based on data from the US-based Kaiser Permanente Northern California database, which were exposed to iodinated contrast…
- Trial name
- NCT02959827
- Testing
- Iodinated contrast agents
- Where
- United States
- Volunteers
- 2,320 people
- Sponsor
- Bayer
Intraplaque Neovascularization Evaluated by Carotid Enhanced Ultrasound Well Reflect the Plaque Vulnerability
Serum Biomarker of Plaque Vulnerability and Contrast Ultrasound of Carotid Artery
No serum biomarker has qualified for clinical use until now. However several biomarkers, especially markers of inflammatory or proteolytic activity seem to promising in the identification of vulnerable plaques.
- Trial name
- NCT01842490
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Kyunghee University Medical Center
Fibrosis, Kidney Failure
Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Moderate Renal Insufficiency After the Administration of Magnevist
Assess potential risk for NSF in subjects with renal impairment (moderate) post magnevist injection. Subjects will be screened within 48 hours of previously scheduled MRI, those meeting the enrollment criteria will be enrolled…
- Conditions
- Fibrosis, Kidney Failure, Renal Insufficiency
- Trial name
- NCT00744939
- Testing
- Gadopentetate dimeglumine (Magnevist, BAY86-4882)
- Where
- 26 sites in United States
- Volunteers
- 168 people
- Sponsor
- Bayer
Visual Fatigue
Visual Discomfort and Reading
Reading can be an uncomfortable and difficult task for some people. Symptoms include unpleasant somatic and perceptual effects, such as eye-strain, headache, and blurred text, despite normal visual acuity.
- Trial name
- NCT00402155
- Testing
- Stress on visual discomfort
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Tetralogy of Fallot, Pulmonary Insufficiency
Contrast Enhanced 3D Echocardiographic Quantification of Right Ventricular Volumes in Repaired CHD
We propose the novel integration of two echocardiographic technologies - three-dimensional echocardiography using semi-automated right ventricular analysis coupled with the administration of ultrasound enhancing agents - to…
- Trial name
- NCT05186415
- Testing
- Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nemours Children's Clinic
Renal Function Disorder, Hemodynamic Instability
The Effects of Dexmedetomidine on Early Stage Renal Functions in Pediatric Patients
The aim of this study is to evaluate the effect of dexmedetomidine infusion on early stage renal function.
- Trial name
- NCT01948336
- Testing
- Dexmedetomidine, Ketamine, Propofol
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Contrast-induced Acute Kidney Injury, Microalbuminuria
Microalbuminuria Predicting CIAKI After CAG
The purpose of this study is to investigate the association between pre-existing microalbuminuria and contrast-induced acute kidney injury (CIAKI) following coronary angiography (CAG).
- Trial name
- MPCC (NCT02808845)
- Testing
- microalbuminuria
- Where
- China
- Volunteers
- 800 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Acute Kidney Injury
Remote Ischemic Preconditioning to Prevent Contrast Nephropathy
Contrast-medium induced nephropathy (CIN) is a frequent and devastating complication of coronary angiography, occurring in 10-50% of cases.
- Trial name
- RIPC-CIN (NCT02674451)
- Testing
- Remote ischemic preconditioning
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Johns Hopkins University
Breast Diseases
New Mammographic Techniques Versus MRI in Assessment of Breast Lesions
Value of New Mammography Techniques in Comparison to Dynamic Contrast-Enhanced MRI of the Breast in the Detection and Diagnosis of Breast lesions
- Trial name
- CEDM&DBTVSMR (NCT06089148)
- Testing
- contrast enhanced digital mammography, tomosyntheis and MRI
- Volunteers
- 40 people
- Sponsor
- Cairo University
Breast Cancer
Quantitative Dynamic Contrast Enhanced Breast MRI
The purpose of this study is to see if dynamic contrast enhanced (DCE) MRI imaging makes it possible to distinguish benign conditions of the breast from malignant tumors and provide better information than can be obtained with…
- Trial name
- NCT00582764
- Testing
- perform dynamic contrast enhanced (DCE) MRI
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Abdominal Trauma
Contrast Enhanced Ultrasound for Evaluation of Pediatric Abdominal Trauma
The research protocol aims to compare the utility of contrast enhanced abdominal sonography with computerized tomography in the evaluation of children with blunt abdominal trauma.
- Trial name
- NCT01763840
- Testing
- Contrast enhanced Ultrasound
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- David Mooney
Pulmonary Arteriovenous Malformations
Contrast Echocardiography in Patients With Pulmonary Arteriovenous Malformations (PAVMs)
Pulmonary arteriovenous malformations (PAVMs) are thin-walled abnormal vessels which provide direct capillary-free communications between the pulmonary and systemic circulations.
- Trial name
- NCT00733759
- Where
- United Kingdom
- Sponsor
- Imperial College London
Thyroid Papillary Carcinoma, Contrast Enhanced Ultrasound
Preoperative Prediction of Lymph Node Metastasis in T1N0M0 Papillary Thyroid Carcinoma by Using Contrast-enhanced Ultrasound
Similarly, the burden of central lymph node metastasis affects the individualized management of patients with T1N0M0 papillary thyroid carcinoma (PTC): lymph node metastasis is a contraindication to thermal ablation; low-burden…
- Trial name
- NCT07357571
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Liver Neoplasms, Adenoma
Liver MRI With Primovist/Eovist in Pediatric Subjects Who Are Suspected or Have Focal Liver Lesions.
Medical records are reviewed to obtain information about the use of a MRI diagnostic imaging agent (contrast agent) called Primovist/Eovist in children older than 2 months and less than 18 years.
- Conditions
- Liver Neoplasms, Adenoma, Carcinoma, Liver Abscess
- Trial name
- NCT01043523
- Testing
- Gadoxetic Acid Disodium (Eovist, BAY86-4873)
- Where
- 9 sites in United States, Italy and 3 more
- Volunteers
- 52 people
- Sponsor
- Bayer
Abdominal Neoplasms, Pelvic Neoplasms
Determination of a Safe Dose of Optison in Pediatric Patients With Solid Tumors
St. Jude Children's Research Hospital is studying ways to make ultrasound images clearer - to be able to see blood vessels, body structures, and tumors better.
- Trial name
- NCT00186953
- Testing
- Optison
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- St. Jude Children's Research Hospital