Clinical trials: Contrast Agent
Renal Impairment, Limb Ischemia, Critical
Ultra-low Dose Contrast for Endovascular Procedures
The purpose of this protocol is to study the safety and feasibility of using ultra-low dose iodinated contrast agent for infrainguinal endovascular revascularization procedures in patients with chronic limb-threatening lower limb…
- Trial name
- ULTRA-LOW (NCT06835127)
- Testing
- Infrainguinal peripheral endovascular revascularization
- Where
- Greece
- Volunteers
- 18 people
- Sponsor
- Attikon Hospital
Magnetic Resonance Imaging Contrast Agents
Gadolinium-Based-Contrast-Agents (GBCA) Enhancement During MR Urography
Rationale: Dotarem provides superior enhancement characteristics compared to other GBCA in fMRU Specific Aims: Compare enhancement characteristics of Dotarem to other GBCAs in the kidneys used in fMRU Primary Objectives: Review…
- Trial name
- NCT03910114
- Testing
- Magnevist, Dotarem, Gadovist
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Vanderbilt University Medical Center
Necrotizing Enterocolitis of Newborn, Bowel Ischemic
CEUS Evaluation of Bowel Perfusion in Necrotizing Enterocolitis
There is no bedside imaging technique that can quantify dynamic bowel perfusion with high soft tissue contrast and sensitivity in necrotizing enterocolitis (NEC).
- Trial name
- NCT03549507
- Testing
- Sulfur hexafluoride lipid-type A microspheres
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Children's Hospital of Philadelphia
Appendicitis Acute
Contrast-Enhanced Ultrasound Diagnosis of Acute Appendicitis
This study evaluates the ability of contrast-enhanced ultrasound to improve the diagnosis of acute appendicitis in children compared to conventional ultrasound.
- Trial name
- NCT03295656
- Testing
- Sulfur hexafluoride lipid-type A microspheres
- Where
- United States
- Sponsor
- Boston Children's Hospital
Radiofrequency Ablation, Ultrasonography
Added Value of Contrast-enhanced Ultrasonography for Percutaneous Radiofrequency Ablation
Contrast-enhanced ultrasonography (CEUS)-CT/MRI fusion imaging substantially improved the visibility of small tumors that were inconspicuous on both US and US-CT/MRI fusion imaging, contributing to successful percutaneous…
- Conditions
- Radiofrequency Ablation, Ultrasonography, Liver Tumors
- Trial name
- NCT05445973
- Testing
- Percutaneous Radiofrequency Ablation
- Where
- South Korea
- Volunteers
- 248 people
- Sponsor
- Seoul National University Hospital
Small Bowel Obstruction, Contrast Media Adverse Reaction
Use of a Water Soluble Contrast-Based Protocol to Assist in the Management of Pediatric Adhesive Small Bowel Obstruction
The goal of this prospective observational study is to evaluate the diagnostic and therapeutic utility of an enteral contrast challenge for pediatric patients with adhesive small bowel obstruction (ASBO). The aims are to 1.
- Trial name
- SBO (NCT06101719)
- Testing
- Enteral contrast challenge
- Where
- 9 sites in United States
- Volunteers
- 136 people
- Sponsor
- Children's Hospital Colorado
Glioma
MRI Contrast Clearance Analysis for Glioma Grading and Genotyping
Gliomas are the most common primary brain tumor. Gliomas with different grades have different clinical behaviors that determine treatment planning and patient prognosis in clinical practice.
- Trial name
- NCT06018870
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Bladder Cancer, Genitourinary Cancer
A Validation Study of MR Lymphangiography Using SPIO, a New Lymphotropic Superparamagnetic Nanoparticle Contrast
The goal of this clinical research study is to evaluate how well ferumoxtran-10, a new Magnetic Resonance Imaging (MRI) contrast agent, can detect cancer in the pelvic lymph nodes or malignant pelvic lymph nodes.
- Conditions
- Bladder Cancer, Genitourinary Cancer, Prostate Cancer
- Trial name
- NCT00147238
- Testing
- Ferumoxtran-10 (USPIO), MR lymphangiography
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- M.D. Anderson Cancer Center
Lactose Intolerance
MSOT for Assessment of Intestinal Transit Time in Lactose Intolerance Patients
The study aims to investigate gastrointestinal transit using multispectral optoacoustic tomography (MSOT) in a prospective diagnostic study involving patients suspected of primary or secondary lactose intolerance.
- Trial name
- NCT06617364
- Testing
- gastrointestinal transit time measurement using MSOT and ICG contrast agent
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Contrast Enhanced X-ray Based Examination
A Study, Called UV Population, to Learn More About the Safety of the Study Drug Ultravist, Which is Given to Get Clearer X-ray Pictures, in People of Different Sexes, Races, and From Different Countries/Regions
This is an observational study in which patient data from the past of people who received Ultravist prior to an X-ray based scan are studied.
- Trial name
- NCT05428397
- Testing
- Iopromide (Ultravist, BAY86-4877)
- Where
- Germany
- Volunteers
- 152,233 people
- Sponsor
- Bayer
Coronary Artery Disease
N-GAL Allows Intensive Treatment of Contrast Induced Nephropathy
Patients who undergo urgent/emergency coronary angiography can not receive any preventive treatment of contrast induced nephropathy.
- Trial name
- NEW-MOON (NCT01491243)
- Testing
- Intensive treatment with sodium bicarbonate, Standard treatment with saline infusion
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Abdominal Injuries, Physical Abuse
Effectiveness of Contrast-Enhanced Ultrasound
The purpose of the study is to generate pilot data describing test characteristics of contrast enhanced ultrasound in young children with concern for abdominal trauma.
- Conditions
- Abdominal Injuries, Physical Abuse, Accidental Fall, Motor Vehicle Injury
- Trial name
- NCT03473249
- Testing
- Contrast-Enhanced Ultrasound using Lumason
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Chronic Kidney Disease stage3, Contrast-induced Nephropathy
Renoprotective Effect of Febuxostat on Contrast Induced Acute Kidney Injury in Chronic Kidney Disease Patients Stage 3
This study will determine the renoprotective effect of febuxostat in prevention of contrast induced acute kidney injury in chronic kidney disease patients Stage 3 undergoing percutaneous coronary intervention.
- Trial name
- NCT05264584
- Testing
- Isotonic saline, N-acetyl cysteine, Febuxostat 80 MG
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Patient Participation
Safety and Performance of Optivantage Multi-use When Injecting Contrast Media for Contrast Enhanced CT Examination
The study is a prospective, single-arm observational multicenter clinical investigation. The primary objective is to confirm the safety and performance of the Optivantage® Injection System when injecting contrast media to…
- Trial name
- NCT05537779
- Testing
- CT examination
- Volunteers
- 100 people
- Sponsor
- Guerbet
Acute Renal Insufficiency
Incidence of Acute Renal Failure Associated With Iodinated Contrast Agents in Pediatrics
Iodinated contrast media are now frequently used in diagnostic imaging exams, including pediatrics. In adults, the acute renal failure (ARF) associated with contrast agents (CA-AKI) occur in 3-33% of exposed patients, especially…
- Trial name
- CANOPY (NCT02955979)
- Testing
- CT scan with iodinated contrast agents
- Where
- 2 sites in France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Atherosclerosis
Magnetic Resonance Angiography (MRA) for the Diagnosis of Atherosclerosis
Magnetic Resonance Angiography (MRA) is a method used to evaluate arteries and veins without the use of invasive catheters or x-rays (radiation).
- Trial name
- NCT00001841
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Focal Liver Lesions, Contrast-enhanced Ultrasound
Radiomics Analysis of Focal Liver Lesions Based on Contrast-Enhanced Ultrasound Imaging
Contrast-enhanced ultrasound (CEUS) substantially improves the potential of ultrasound (US) for the identification and characterization of focal liver lesions (FLLs).
- Trial name
- NCT04682886
- Testing
- diagnosis
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Ping Liang
AKI, Contrast-induced Nephropathy
Establishing Clinical Utility of a New Diagnostic Test in Patients Undergoing Cardiac Catheterization
This study will collect high-quality randomized controlled data across the U.S. from practicing cardiologists performing invasive/interventional procedures and determine how they currently manage patients at risk for CIN and how…
- Trial name
- NCT04266834
- Testing
- Experimental Arm
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Clear Cell Renal Cell Carcinoma, Prognostic Cancer Model
Contrast-enhanced CT-based Deep Learning Model for Preoperative Prediction of Disease-free Survival (DFS) in Localized Clear Cell Renal Cell Carcinoma (ccRCC)
This study aims to preoperatively predict DFS of patients with localised ccRCC using a deep learning prognostic model based on enhanced contrast CT images, validate it's predictive ability in multicentre data and compare it's…
- Conditions
- Clear Cell Renal Cell Carcinoma, Prognostic Cancer Model, Recurrent Renal Cell Cancer
- Trial name
- NCT06088134
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Mingzhao Xiao
Prostate Cancer
Quantitative Prostate Cancer Contrast-enhanced Ultrasound
Background: Bracco has released the VueBoxTM-Prostate software, aimed at distinguishing prostate cancer from prostate benign peripheral zone (PZ) at contrast-enhanced ultrasound (CEUS) using SonoVue® as contrast agent.
- Trial name
- SONOCAP (NCT02295449)
- Testing
- biopsy sample performed after the SonoVue® injection
- Where
- 3 sites in France
- Volunteers
- 130 people
- Sponsor
- Hospices Civils de Lyon