Clinical trials: Contrast Agent
Amnesia, Dementia
Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders
This study is divided into two parts. The first part of the study will use MRI technology to view the brain structure of patients with neurological disorders and normal volunteers.
- Conditions
- Amnesia, Dementia, Healthy, Nervous System Disease
- Trial name
- NCT00001362
- Where
- United States
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Hypersensitivity
Role of Skin Tests for the Diagnosis of Immediate Hypersensitivity Reactions Due to Iodinated Contrast Media
The purpose of this trial is to study the diagnostic role of skin test in immediate reactions to iodinated radiocontrast media.
- Trial name
- NCT00819494
- Testing
- Skin tests with radiocontrast media
- Where
- Thailand
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Renal Insufficiency
Evaluation of the Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Chronic Kidney Disease Without Exposure to Gadolinium Based Contrast Agents (GBCA)
The objective of this long term study is to prospectively evaluate the incidence of NSF in patients with severe CKD or kidney failure including patients undergoing dialysis (stages 4 and 5 i.e., with an eGFR below 30)who have not…
- Trial name
- NCT00773409
- Where
- United States
- Volunteers
- 405 people
- Sponsor
- Bracco Diagnostics, Inc
Appendicitis Acute
Contrast-Enhanced Ultrasound Diagnosis of Acute Appendicitis
This study evaluates the ability of contrast-enhanced ultrasound to improve the diagnosis of acute appendicitis in children compared to conventional ultrasound.
- Trial name
- NCT03295656
- Testing
- Sulfur hexafluoride lipid-type A microspheres
- Where
- United States
- Sponsor
- Boston Children's Hospital
Central Nervous System Indication, Pediatric Patients
Pharmacokinetics, Safety and Efficacy of P03277 in Pediatric Patients Undergoing Central Nervous System Contrast-enhanced MRI
This is a pharmacokinetics (PK), open-label, uncontrolled, multicenter phase II trial with age-staggered approach. The primary objective is to evaluate the PK profile of gadopiclenol in plasma following single IV injection of…
- Conditions
- Central Nervous System Indication, Pediatric Patients, Body Indication
- Trial name
- NCT03749252
- Testing
- P03277
- Where
- 16 sites in Bulgaria, Hungary and 3 more
- Volunteers
- 80 people
- Sponsor
- Guerbet
Neurogenic Bladder
Feasibility of Using Contrast Enhanced Voiding Urosonography (CeVUS) During Urodynamic Studies
The investigators will assess the feasibility of replacing fluoroscopy/iodinated contrast with ultrasound/sulfur hexafluoride lipid-type A microspheres during routine urodynamic studies.
- Trial name
- NCT04170413
- Testing
- CeVUS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Virginia
Radiofrequency Ablation, Ultrasonography
Added Value of Contrast-enhanced Ultrasonography for Percutaneous Radiofrequency Ablation
Contrast-enhanced ultrasonography (CEUS)-CT/MRI fusion imaging substantially improved the visibility of small tumors that were inconspicuous on both US and US-CT/MRI fusion imaging, contributing to successful percutaneous…
- Conditions
- Radiofrequency Ablation, Ultrasonography, Liver Tumors
- Trial name
- NCT05445973
- Testing
- Percutaneous Radiofrequency Ablation
- Where
- South Korea
- Volunteers
- 248 people
- Sponsor
- Seoul National University Hospital
Patients Requiring Abdominopelvic CT With Oral Administration of Contrast
Study With Oral Isovue in Abdominopelvic CT
This is a retrospective clinical study with prospectively designed blinded evaluation of CT images in adult and pediatric patients who underwent CT examinations of the abdomen and pelvis and were orally administered a solution of…
- Trial name
- NCT04453059
- Testing
- Iopamidol
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- Bracco Diagnostics, Inc
Magnetic Resonance Imaging (MRI)
Post-marketing Safety Study in Participants of All Pathologies Who Receive Gadolinium-Based Contrast Agents (GBCAs) for Contrast-Enhanced Magnetic Resonance Imaging (MR) Examination
The purpose of this study is to prospectively collect data on the pattern of use for gadolinium-based contrast agents (GBCAs) in real-life setting with special reference to Clariscan after its commercial launch in Europe and in…
- Trial name
- NCT03455283
- Testing
- Clariscan, Gadolinium-Based Contrast Agents
- Where
- 2 sites in Germany, Norway
- Volunteers
- 2,118 people
- Sponsor
- GE Healthcare
Crohn Disease
Contrast Enhanced Ultrasound in Human Crohn's Disease-Lumason
The investigators plan to compare contrast-enhanced ultrasound to CT and MRI for the detection and quantification of intestinal inflammation in the the setting of pediatric small bowel Crohns disease
- Trial name
- NCT03492944
- Testing
- Ultrasound Microbubble Contrast Agent, Ultrasound Imaging
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Contrast-enhanced MRI With Dotarem
Post-marketing Surveillance Study for Evaluation of Dotarem Safety
Guerbet conducted a non-interventional post-marketing surveillance study on its Magnetic Resonance Imaging (MRI) contrast agent Dotarem (gadoteric acid/gadoterate meglumine).
- Trial name
- NCT03048006
- Testing
- MRI with Dotarem
- Volunteers
- 44,456 people, healthy volunteers welcome
- Sponsor
- Guerbet
Valvular Heart Disease Stenosis and Regurgitation
Different Methods of Cardiac MRI in Assessment of Estimated Corrected Ejection Fraction in Valvular Heart Diseases
Comparative study between Phase Contrast , Modified Simpson Rule and Myocardial Strain Analysis methods of Cardiac Magnetic Resonance Imaging in assessment of Corrected Estimated Ejection Fraction in Valvular Heart Disease To…
- Trial name
- NCT05808465
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Intraplaque Neovascularization Evaluated by Carotid Enhanced Ultrasound Well Reflect the Plaque Vulnerability
Serum Biomarker of Plaque Vulnerability and Contrast Ultrasound of Carotid Artery
No serum biomarker has qualified for clinical use until now. However several biomarkers, especially markers of inflammatory or proteolytic activity seem to promising in the identification of vulnerable plaques.
- Trial name
- NCT01842490
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Kyunghee University Medical Center
Lenses, Intraocular, Glistenings
Impact of Glistenings in AcrySof Intraocular Lenses on Visual Quality
This study will assess the impact of IOL glistenings on visual quality and function in patients implanted with a single-piece AcrySof intraocular lens (IOL) that exhibits glistening formations.
- Conditions
- Lenses, Intraocular, Glistenings, Visual Quality
- Trial name
- NCT01202981
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Utah
Acute Renal Injury
Acute Renal Injury Associated Contrast in Intensive Care Unit Patients
Generally, a contrast medium is used when performing a CT scan or radiographic tests such as angiography because it heightens image clarity and can increase diagnosis accuracy.
- Trial name
- NCT01807195
- Testing
- contrast medium usage
- Where
- South Korea
- Volunteers
- 886 people
- Sponsor
- Yonsei University
Sports
Effects of Contrast Strength Training in Badminton Players
Badminton is one of the most popular sports worldwide. In general, badminton jumping actions have two goals: achieve maximum height and reach a precise location using certain body movements.
- Trial name
- NCT06955091
- Testing
- contrast strength training
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Kidney Disease stage3, Contrast-induced Nephropathy
Renoprotective Effect of Febuxostat on Contrast Induced Acute Kidney Injury in Chronic Kidney Disease Patients Stage 3
This study will determine the renoprotective effect of febuxostat in prevention of contrast induced acute kidney injury in chronic kidney disease patients Stage 3 undergoing percutaneous coronary intervention.
- Trial name
- NCT05264584
- Testing
- Isotonic saline, N-acetyl cysteine, Febuxostat 80 MG
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Postoperative Renal Function
Intraoperative Laser Speckle Imaging Predicts Early Renal Function After Kidney Transplantation
This observational study aims to explore the predictive value of intraoperative laser speckle contrast imaging for early postoperative renal function in kidney transplant recipients.
- Trial name
- NCT07753434
- Testing
- laser speckle contrast imaging (LSCI)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Gadolinium, MultiHance
Gadolinium Retention in Human Bone Tissue in Pediatric Patients
The purpose of this study is to compare contrast agents, Dotarem or MultiHance. The study will test to see how much of these two contrast agents are deposited in the bones or tissues of pediatric patients.
- Conditions
- Gadolinium, MultiHance, Dotarem, Magnetic Resonance Imaging
- Trial name
- NCT03337594
- Testing
- Pre-operative MRI with Dotarem, Pre-operative MRI with MultiHance, Surgery
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Donna Roberts
Pediatric Congenital Heart Disease
Feraheme As An MRI Contrast Agent For Pediatric Congenital Heart Disease
The standard clinical cardiovascular MRI practice for children with CHD frequently involves the use of gadolinium-based contrast agents (GBCA) to enhance tissue contrast.
- Trial name
- NCT02752191
- Testing
- ferumoxytol, gadofosveset
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Paul Finn