Clinical trials: Control
Migraine
Efficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine
This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and adolescents (12 to <18 years) with episodic migraine.
- Trial name
- OASIS(EM) (NCT03836040)
- Testing
- Erenumab Dose 1, Erenumab Dose 2, Erenumab Dose 3
- Where
- 11 sites in United States, Belgium and 2 more
- Volunteers
- 457 people
- Sponsor
- Amgen
White Spot Lesion
Effectiveness of Different Remineralizing Strategies on the Management of Early Carious Lesions in Primary Teeth
the primary aim of the study is remineralization of early carious lesions in primary teeth using different remineralizing agents of different remineralizing strategies when applied in an intensive mode.
- Trial name
- NCT06566833
- Testing
- self assmbling peptide p11-4 combined with 0.05% fluoride, Casein phosphopeptide amorphous calcium phosphate, 5% sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Self Care
Evaluation of the Eversense Continuous Glucose Monitoring System in Type I Diabetic Youth
The purpose of this clinical investigation is to provide pilot clinical data to direct pivotal study development for the pediatric indication of the Senseonics Continuous Glucose Monitoring System (CGM) measurements when compared…
- Trial name
- FNH (NCT03815552)
- Testing
- Eversense Continuous Glucose Monitoring
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Kinderkrankenhaus auf der Bult
ADHD
Impact of the MIND Diet on ADHD Symptoms in Untreated Children
This study, titled "The Effect of the MIND Diet on ADHD Symptom Severity in Children with ADHD Not on Pharmacotherapy: A Randomized Controlled Trial in Lebanon," aims to evaluate whether a structured dietary intervention can…
- Trial name
- NCT07686458
- Testing
- MIND Diet (Mediterranean-DASH Intervention for Neurodegenerative Delay) Dietary Intervention
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Tinea Capitis
Selenium Sulfide, Ketoconazole and Ciclopirox Shampoo as Additional Treatments for Tinea Capitis (Scalp Ringworm)
Antifungal shampoos have been used as supplements to oral griseofulvin to help eradicate tinea capitis (also known as ringworm of the scalp) more quickly.
- Trial name
- NCT00127868
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Chen, Catherine, M.D.
Nausea Gravidarum, Anxiety
Emotional Freedom Technique in Early Pregnancy
One of the most common discomforts in early pregnancy is nausea and vomiting. Although its etiology is not known exactly, it affects an average of 50-90% of pregnant women.
- Conditions
- Nausea Gravidarum, Anxiety, Emotion Regulation, Vomiting of Pregnancy
- Trial name
- NCT05337852
- Testing
- Emotional Freedom Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Inonu University
Virtual Reality, Epilepsy
Effect of VR-ESMEPP on Parents' Seizure Management
Objective: This study aims to evaluate the knowledge, skills, and motivation of parents regarding management of epileptic seizures, by developing a "Virtual Reality Based Seizure Management Education Program for Parents…
- Conditions
- Virtual Reality, Epilepsy, Seizure, Child
- Trial name
- VR-ESMEPP (NCT05500638)
- Testing
- Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Tendon Injury - Hand
Passive Mobilization With Place and Hold vs Active Mobilization Therapy After Flexor Tendon Repair
The aim of this study is to investigate if active mobilisation after flexor tendon repair in fingers gives better range of motion, strength, risk of rupture and patient satisfaction compared with passive mobilisation with place…
- Trial name
- NCT04385485
- Testing
- Active mobilisation, Passive mobilisation with place and hold
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Sahlgrenska University Hospital
Acute Renal Colic
Diclofenac IM Versus Tramadol IV in Acute Renal Colic, RCT
Patients presented with acute pain from renal colic, the standard of care are prescribed NSAIDs, most common drug used is intramuscular (IM) Diclofenac injected at the gluteal muscle.
- Trial name
- NCT06231043
- Testing
- Diclofenac/Tramadol
- Where
- Thailand
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Lampang Hospital
Hypoxic Ischaemic Encephalopathy (HIE)
EFFICACY OF MELATONIN IN MANAGEMENT OF HYPOXIC ISCHEMIC ENCEPHALOPATHY (HIE) IN NEONATES
To compare the survival rate and improvement in stage of hypoxic ischemic encephalopathy (HIE) at day 7 of treatment in neonates treated with versus without melatonin in addition to standard supportive therapy.
- Trial name
- NCT07305350
- Testing
- Melatonin, intravenous (IV) fluids, intensive monitoring, broad-spectrum antibiotic cover
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore
Methylmalonic Aciduria and Homocystinuria,Cblc Type, Genetic Disease
EPI-743 in Cobalamin C Defect: Effects on Visual and Neurological Impairment
The aim of the research is to investigate the safety and efficacy of EPI-743 treatment in patients with Cbl-C defect and related visual and neurological impairment.
- Conditions
- Methylmalonic Aciduria and Homocystinuria,Cblc Type, Genetic Disease, Retinopathy
- Trial name
- NCT01793090
- Testing
- Epi-743
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Attention Deficit Hyperactivity Disorder
A 6-week Study to Evaluate the Safety and Efficacy of Methylphenidate HCl ERCT in 4-5 Year Old Children With ADHD
This 6-week study is to determine if the study drug, Methylphenidate Hydrochloride (HCl) Extended-Release Chewable Tablets (ERCT), is safe, tolerable and effective when compared to a sugar pill or placebo in children 4 to 5 years…
- Trial name
- NCT03536390
- Testing
- Methylphenidate Hydrochloride (HCl) Extended Release Chewable Tablet (ERCT)
- Sponsor
- Pfizer
Cancer (Solid Tumors), Cancer and / or Hematological Malignancy
Comparative Effectiveness of Verbal Instruction Versus Simulation Video Education Among Cancer Patients Undergoing Radiation Therapy
The goal of this Randomized Controlled Trial is to compare the effectiveness of radiotherapy-specific, physician-led educational videos introduced before the initial Radiation Therapy consultation .
- Trial name
- CARE-RT (NCT07367997)
- Testing
- Radiotherapy-Specific Educational Video
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Cow Milk Protein Allergy
Impact of Zinc as a New Adjuvant Therapy for Cow Milk Protein Allergy in Children.
Children presented with manifestations of Cow Milk Protein Allergy will be enrolled for Cow Milk -related Symptoms Score (CoMiSS assessment).
- Trial name
- NCT06673082
- Testing
- Oral zinc supplementation
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Kasr El Aini Hospital
Musculoskeletal Disorders
Triaging Patients With Musculoskeletal Disorders Directly to Physiotherapists at Primary Health Care Clinics.
The purpose of this study is to determine whether initial triaging to physiotherapists of patients with musculoskeletal disorders who seek health care from primary care clinics affects the patients health and/or health care…
- Trial name
- NCT02218749
- Testing
- Initially triaged to physiotherapist, Initially triaged to physician
- Where
- 3 sites in Sweden
- Volunteers
- 55 people
- Sponsor
- Göteborg University
Amputation
Amputee Residual Limb Volume Fluctuation
The goal of this project is a useful clinical instrument for diagnosis and treatment of residual limb volume fluctuation in individuals who use prosthetic limbs.
- Trial name
- NCT01161238
- Testing
- Monitored for limb volume
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Washington
Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression (DAL)
This is a mono-centre, prospective, one-arm, unmask clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation compared to a single vision spectacle lens from…
- Trial name
- NCT05840185
- Testing
- Test myopia control lenses (DAL)
- Where
- Singapore
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Essilor International
Adherence, Engagement
MyPocketPal Feasibility Study
Participants will take part in a 4-week study consisting of two in-person sessions. During the first session, participants will complete a demographic form and baseline questionnaire, after which the study application will be…
- Trial name
- NCT07668843
- Testing
- MyPocketPal, Control
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Orthodontic Appliance Complication
Evaluation of Maxillary Canine Retraction Assisted With Two Different Methods of Low-Intensity Pulsed Ultrasound
The current clinical study will be done for evaluation of maxillary canine retraction assisted with application of two different methods of low-intensity pulsed ultrasound.
- Trial name
- NCT05692817
- Testing
- Low-Intensity Pulsed Ultrasound
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ammar Kasem Alzoubi
Congenital Heart Disease in Children, RSV
Adherence to Palivizumab Prophylaxis
The goal of this clinical trial is to analyze implications of two alternative nudge-interventions to increase adherence to palivizumab prophylaxis in children with congenital heart disease.
- Trial name
- NCT05778240
- Testing
- Phone call, Text message, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 229 people
- Sponsor
- Kosuyolu Heart Hospital