Clinical trials: Controlled Diabetes
Type 1 Diabetes
Sleep and Type 1 Diabetes
The primary goal of the study is to determine whether insufficient sleep is associated with poor glycemic control in type 1 diabetic children.
- Trial name
- SLEEPT1D (NCT02494375)
- Testing
- Sleep and glucose assessments
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Type 1 Diabetes
Evaluating the InPen in Pediatric Type 1 Diabetes
Type 1 Diabetes (T1D) is the most common form of diabetes affecting children, requiring lifelong administration of insulin to prevent complications.
- Trial name
- EMPoWER (NCT05515939)
- Testing
- InPen Insulin Pen
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Wayne State University
Diabetes Mellitus Type 2
A Study to Evaluate BMS-986036 in Obese Adults With Type-2 Diabetes
The purpose of this study is to assess the potential of BMS-986036 for treatment obese adults with type-2 diabetes.
- Trial name
- NCT02097277
- Testing
- BMS-986036
- Where
- 16 sites in United States, Canada
- Volunteers
- 219 people
- Sponsor
- Bristol-Myers Squibb
Diabetes, Diabetes Mellitus, Type 1
A Survey to Evaluate Diabetes Management, Control, Chronic Complications, Psychosocial Aspects of Diabetic Subjects in India
This study is conducted in Asia. The aim of this observational study is to evaluate the current status of diabetes management, control, and complications in diabetic subjects in India.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- DiabCare India (NCT01351922)
- Testing
- No treatment given
- Where
- India
- Volunteers
- 12,000 people
- Sponsor
- Novo Nordisk A/S
Impaired Glucose Tolerance, Diabetes
Effect of Ginseng on Glycemic Control
Ginseng (American ginseng, Asian ginseng, Korean ginseng etc) is expected to show positive hypoglycemic effects, including improvements in glycated blood proteins[HbA1c], fasting glucose, fasting insulin, and the homeostasis…
- Trial name
- NCT01841229
- Where
- Canada
- Volunteers
- 770 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Diabetes Mellitus, Type 2
Study to Evaluate Safety and Efficacy of Dapagliflozin and Saxagliptin in Patients With Type 2 Diabetes Mellitus (T2DM) Aged 10 to Below 18 Years Old
The primary objective of this study is to determine if there will be a greater mean reduction from baseline in glycated hemoglobin (HbA1c) achieved after 26 weeks of oral double-blind add-on therapy of dapagliflozin or…
- Trial name
- NCT03199053
- Testing
- Dapagliflozin, Saxagliptin
- Where
- 122 sites in United States, Argentina and 21 more
- Volunteers
- 256 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Diabetes Mellitus, Type 1
Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patients Lack of Predictive Value: a Multicenter Nested Case-control Study
The goal of this observational study is to evaluate the predictive value of the genetic risk score for type 1 diabetes in the progression to insulin deficiency in diabetic patients. The main question it aims to answer is: 1.
- Trial name
- NCT07621445
- Where
- China
- Volunteers
- 2,950 people
- Sponsor
- Second Xiangya Hospital of Central South University
Type 1 Diabetes
Group Visits for High Risk Type 1 Diabetes (T1D)
The investigators propose to conduct a pilot prospective cohort study to assess the impact of shared medical appointments (SMA) visits in underserved youth with poorly controlled type 1 diabetes (T1D).
- Trial name
- NCT05431686
- Testing
- SMA visits
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Children's National Research Institute
Diabetes Mellitus, Type 1
Interventions to Prevent Adolescents With Type 1 Diabetes From Long-term Complications
The purpose of this study is to evaluate the effectiveness of diabetes management training combined with the method of Motivational Interviewing with elements of Cognitive Behaviour Therapy and E-mail support in the treatment of…
- Trial name
- NCT01520428
- Testing
- Motivational Interviewing, CBT and E-mail support
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Diabetes Mellitus, Type 1
An Open-label, Two-center, Randomized, Cross-over Study to Evaluate the Safety and Efficacy of Glycemic Control Using Hybrid-closed Loop vs. Advanced Hybrid Closed-loop in Young Subjects With Type 1 Diabetes
Closed-loop systems are becoming an integral part of diabetes management. These systems were uniformly proven to improve glycemic control, reduce hyperglycemia and hypoglycemia while modestly reducing HbA1c levels and improving…
- Trial name
- NCT04269668
- Testing
- Medtronic Minimed 670G 3.0 HCL, Medtronic Minimed 670G 4.0 AHCL
- Where
- 2 sites in Germany, Israel
- Volunteers
- 28 people
- Sponsor
- Rabin Medical Center
Metabolic Cardiovascular Syndrome
Health Improvement After Pregnancy (HIP) Program Randomized Control Trial
Recent Canadian studies, public opinion polls and the Canadian Heart Health Strategy and Action Plan state that women's heart health is a key national priority; it should be addressed through improving heart health awareness and…
- Trial name
- HIP (NCT02077179)
- Testing
- HIP Program
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- Queen's University
Type 1 Diabetes
Atorvastatin in New Onset Type 1 Diabetes Mellitus (T1DM)
The goal of this application is to evaluate the safety and efficacy of atorvastatin as a potential treatment to preserve beta cell function in children and young adults with newly diagnosed type 1 diabetes (T1DM).
- Trial name
- TIDM (NCT00529191)
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Philadelphia
Type 2 Diabetes
Type 2 Continuous Glucose Monitoring Academy
The goal of this clinical trial is to evaluate the Impact of Continuous Glucose Monitoring Academy Education Curriculum Versus Standard Care on Glycemic Outcomes for Youth With Type 2 Diabetes (T2D): The first aim is to determine…
- Trial name
- NCT06516640
- Testing
- Continuous Glucose Monitoring Academy, Standard Education
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Los Angeles
Type1 Diabetes Mellitus
Comparison of Real-time CGMS With Intermittently-scanned CGMS in Adolescents and Adults With Type 1 Diabetes Mellitus
Type 1 Diabetes Mellitus (T1DM) is characterized by absolute insulin deficiency. Despite multiple daily insulin injections, glycemic targets are usually not achieved in T1DM patients.Use of continuos glucose monitoring system…
- Trial name
- NCT05928260
- Testing
- Medtronic Guardian Connect Sensor 3, Abott Freestyle Libre Sensor, Self blood Glucose monitoring by a glucometer
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Type 1 Diabetes
The Performance of an Artificial Pancreas at Home in People With Type 1 Diabetes
The overall aim of the study is to evaluate the performance of Artificial Pancreas or Closed Loop Glucose-Sensing Insulin-Delivery system in comparison to current best available technology represented by Sensor Augmented Pump…
- Trial name
- NCT02040571
- Testing
- Closed Loop, Open Loop
- Where
- Australia
- Volunteers
- 28 people
- Sponsor
- St Vincent's Hospital Melbourne
Diabetes Mellitus, Type 1
Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100…
- Trial name
- NCT05743244
- Testing
- Abrocitinib 200 MG Oral Tablet, Ritlecitinib
- Where
- 30 sites in United States, Australia and 1 more
- Volunteers
- 78 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type1diabetes
Family-Based Behavioral Medical Nutrition Therapy Education in Children and Adolescents With Type 1 Diabetes
Type 1 Diabetes Mellitus (T1DM) is a heterogeneous condition and is an absolute insulin deficiency resulting from autoimmune-mediated destruction of pancreatic β-cells (1).
- Trial name
- NCT05411952
- Testing
- Medical nutrition therapy and carbohydrate counting education, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Hasan Kalyoncu University
Type 1 Diabetes
Family Routines Enhancing Adolescent Diabetes by Optimizing Management
A three month randomized study to examine the potential benefits of sleep extension in tandem with clinical trial on diabetes management in youth with type 1 diabetes.
- Trial name
- FREADOM (NCT02974309)
- Testing
- Sleep Extension, Routine
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Arizona
Diabetes
Meta-analysis of Low GI/GL Diets and Cardiometabolic Risk in Diabetes
Low glycemic index and low glycemic load diets have been shown to improve glycemic control and cardiometabolic risk factors in randomized controlled trials in people with diabetes and are associated with reduced incidence of…
- Trial name
- NCT04045938
- Testing
- Low Glycemic Index or Glycemic Load
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Diabetes Mellitus, Liver Transplant; Complications
Effect of Dapagliflozin vs Sitagliptin on Liver Fat Accumulation and Body Composition in Patients With Diabetes Mellitus and Liver Transplantation
Patients with pre-transplantation type 2 diabetes (T2D) and new-onset diabetes post liver transplantation (NODAT) are managed with multiple doses of subcutaneous insulin (MSI) following liver transplantation.
- Trial name
- Dapa-LiT (NCT05042505)
- Testing
- Dapagliflozin 10Mg Tab, Sitagliptin 100mg
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Medanta, The Medicity, India