Clinical trials: Corona Virus Disease
Multiple Osteochondroma, Osteogenesis Imperfecta
Resilience and Coping in a Rare Skeletal Disease Population to Face Coronavirus (COVID-19) Outbreak Distress: a Longitudinal Study
In the COVID-19 outbreak context, people living with rare diseases have been highly troubled with anxiety, loneliness, and depression.
- Conditions
- Multiple Osteochondroma, Osteogenesis Imperfecta, Ollier Disease, Maffucci Syndrome
- Trial name
- RELOAD (NCT04844697)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
COVID-19 Pneumonia, COVID-19 Respiratory Infection
Follow-up of Covid-19 Long Term Sequelae
The protocol, in accordance with the objectives of ORCHESTRA project - Work Package 2, aims at investigating the characteristics and determinants of COVID-19 long-term sequelae.
- Conditions
- COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Acute Bronchitis, COVID-19 Acute Respiratory Distress Syndrome
- Trial name
- NCT05097677
- Testing
- Not applicable (observational study)
- Where
- 7 sites in Belgium, France and 4 more
- Volunteers
- 7,599 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Covid19
Evolution of COVID-19 in Anticoagulated or Antiaggregated Patients (CORONA Study)
CORONA is a retrospective, observational, one center study to investigate the clinical evolution (in terms of survival and thromboembolic complications) of patients on chronic treatment with anticoagulants or antiplatelet agents…
- Trial name
- CORONA (NCT04518735)
- Testing
- Antithrombotic Therapy (anticoagulant and/or antiplatelet) before admission for Covid19
- Where
- Spain
- Volunteers
- 1,707 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Corona Virus Infection, Flu Vaccine
Understanding Immunity to the Flu Vaccine in COVID-19 Patients
The purpose of this study is to measure immunity to the flu vaccine over time in patients who have had COVID-19 and may have other medical conditions including obesity, type 2 diabetes, chronic fatigue, or long-term COVID-19…
- Conditions
- Corona Virus Infection, Flu Vaccine, Immunity
- Trial name
- NCT04579588
- Testing
- Flu shot
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Stanford University
COVID-19 Pandemic, Nurse's Role
The COVID-19 Pandemic Process Increase Latex Glove Use and Latex Allergy Complaints in Hospital Nurses? Survey Study
Background: Global guidelines recommend the use of personal protective equipment due to the high risk of contagiousness of COVID-19 disease.
- Conditions
- COVID-19 Pandemic, Nurse's Role, Allergy, Latex Allergy
- Trial name
- COVID19LATEX (NCT05515276)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Health Literacy
Digital Health Literacy Intervention for Disadvantaged Women During Corona
The aim is to deliver a digital health literacy intervention to disadvantaged women to improve their health behaviors with regard to (i) hygiene and sanitation, and (ii) coronavirus awareness and prevention in four provinces of…
- Trial name
- NCT04603092
- Testing
- Digital Health Literacy Intervention
- Where
- Pakistan
- Volunteers
- 1,010 people
- Sponsor
- Forman Christian College, Pakistan
COVID, Drug Effect
New Antiviral Drugs for Treatment of COVID-19
Background: In December 2019, SARS-CoV-2 was isolated on Vero E6 and Huh7 cell lines after an outbreak of pneumonia of unknown origin in Wuhan, Hubei Province, China.
- Trial name
- NCT04392427
- Testing
- Treatment group: will receive a combination of Nitazoxanide, Ribavirin and Ivermectin for a duration of seven days :
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Critical Illness, Corona Virus Infection
Anti-IL6 and Corticosteroid Monotherapy vs Combination in COVID-19
The cytokine storms mediated by over production of proinflammatory cytokines have been observed in a large population of critically ill patients infected with COVID-19.
- Conditions
- Critical Illness, Corona Virus Infection, Cytokine Release Syndrome
- Trial name
- NCT04486521
- Testing
- Interleukin 6 (IL6) Antagonist, Interleukin 6 (IL6) Antagonist and corticosteroids, corticosteroid alone
- Where
- Saudi Arabia
- Volunteers
- 860 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Cystic Fibrosis
Covid-19 Antibody Responses in Cystic Fibrosis
Coronavirus disease 2019 (COVID-19) which is caused by the virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has resulted in an ongoing global pandemic.
- Trial name
- CAR-CF (NCT05012306)
- Where
- 8 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Universitätsklinikum Köln
Covid19
CORONA in the Saarland
The CORSAAR study is an observational, prospective study to investigate the natural biology of COVID-19
- Trial name
- CORSAAR (NCT04837755)
- Testing
- Cytokine measurements
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Universität des Saarlandes
COVID, Corona Virus Infection
RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study
This research aims to assess the use of an experimental and non-invasive procedure, Remote Ischemic Conditioning (RIC), as an adjunct therapy in attenuating severe COVID-19 disease.
- Conditions
- COVID, Corona Virus Infection, Acute Lung Injury, Ischemia Limb
- Trial name
- NCT04659460
- Testing
- Remote Ischemic Conditioning
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
COVID
Egyptian Initial Experience About 2019 Novel Corona Virus: Study of 48 Patients in Alexandria-Egypt Using Chest CT
Background: Corona virus disease 2019 (COVID-19) is a highly infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Trial name
- NCT04382469
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Alexandria University
Corona Virus Infection
Covid-19 Convalescent Plasma as Prevention and Treatment for Children With Underlying Medical Conditions
This study will provide access to investigational anti-SARS-CoV-2 human convalescent plasma for pediatric patients with underlying medical conditions (cardiovascular disease, lung disease, immunosuppression) who are either…
- Trial name
- NCT04462848
- Testing
- anti-SARS-CoV-2 human convalescent plasma
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Covid19, Corona Virus Infection
A Study of Baricitinib (LY3009104) in Children With COVID-19
The purpose for this study is to determine if the study drug baricitinib is effective and safe in hospitalized pediatric participants with Coronavirus disease 2019 (COVID -19) and to confirm the dose.
- Trial name
- COV-BARRIER (NCT05074420)
- Testing
- Baricitinib
- Where
- 14 sites in United States, Brazil and 2 more
- Volunteers
- 6 people
- Sponsor
- Eli Lilly and Company
Covid19, Corona Virus Infection
A Follow On Community Testing Study To Evaluate The Performance of the Lucira COVID-19 All-In-One Test Kit
To evaluate the performance of the FDA EUA authorized Lucira COVID-19 All-In-One Test Kit for the qualitative detection of SARS-CoV-2 virus in nasal swab samples as compared to a known high sensitivity EUA RT-PCR among…
- Trial name
- NCT04720235
- Testing
- Lucira COVID-19 All-In-One test kit
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Lucira Health Inc
Anosmia, Ageusia
Investigating Anosmia and Ageusia in COVID-19 Adult Patients in Saudi Arabia
COVID-19 has adversely affected the healthcare system across the world. The world was not prepared for global outbreak of infectious diseases.
- Conditions
- Anosmia, Ageusia, Covid19, Corona Virus Infection
- Trial name
- NCT04388618
- Testing
- NHANES smell and taste tests
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 250 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
COVID, Corona Virus Infection
Seroprevalence of SARS-Cov-2 Antibodies in Children
It is unknown what proportion of healthy children have been exposed to SARS-Cov-2 and how many have antibodies. The aim of this study is to follow a cohort of healthy children over six months and measure their antibodies to…
- Conditions
- COVID, Corona Virus Infection, Multisystem Inflammatory Syndrome in Children
- Trial name
- NCT04347408
- Testing
- Covid-19 Antibody testing (IgG and IgM), Blood Storage
- Where
- 5 sites in United Kingdom
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
COVID-19
Efficacy of a Multiplex BangasureTM RT-PCR Kit for the Detection of COVID-19
The outbreak of the severe acute respiratory syndrome (SARS) corona virus (CoV)-2 continues to increase globally. To control the coronavirus disease 2019 (COVID-19) transmission, diagnose is very important step which would help…
- Trial name
- COVID-19 (NCT05190016)
- Where
- Bangladesh
- Volunteers
- 150 people
- Sponsor
- DR. MALA KHAN
Coronavirus
The Effect of Video Information on Anxiety in Adolescents Having rRT-PCR Test During Corona Virus Pandemic
The Polymerase Chain Reaction (rRT-PCR) test is still the gold standard in the diagnosis of coronavirus disease. Health workers apply this procedure in a closed area, wearing personal protective equipment.
- Trial name
- NCT05265390
- Testing
- Adolescents watching an informational video
- Where
- Turkey (Türkiye)
- Volunteers
- 272 people
- Sponsor
- Mersin University
Diabetes Mellitus, Type 1
Anti-viral Action Against Type 1 Diabetes Autoimmunity
The study GPPAD-05 AVAnT1A is a phase 4 clinical trial intending to enroll 2252 children, who will be randomly assigned to receive COVID-19 vaccination (Comirnaty® 3 μg Omicron XBB.1.5 or new variant Comirnaty vaccines ) or…
- Trial name
- NCT06452654
- Testing
- Comirnaty Injectable Product, Sodium Chloride 0.9% Inj
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 2,252 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich