Clinical trials: Craniofacial Surgery
Cleft Palate
Suprazygomatic Block in Cleft Palate Surgery in Children
Cleft palate (CP) is a common congenital malformation, with an incidence ranging from 0.1 to 1.1 per 1000 births depending on the population group (liau et al, 2010).
- Trial name
- NCT03412474
- Testing
- Bupivacaine, Dexmedetomidine, paracetamol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Orthognathic Surgery, Maxillofacial Abnormalities
Accuracy of Maxillary Repositioning During Orthognathic Surgery
Orthognathic surgery aims to correct jaw position taking into account esthetic and functional criteria (dental occlusion, lip position, breathing...). These surgeries are planned using clinical, radiological and dental cast data.
- Trial name
- POMOCOBS (NCT03357211)
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Maxillofacial Abnormalities
Mandibular Stability and Dentofacial Deformity
The present study intends to clarify whether there is positional mandibular stability in patients to be submitted to orthognathic surgery.
- Trial name
- NCT01486069
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Distress
Does Massage With or Without Aromatherapy Reduce Infant's Distress?
This study aims to determine the effect of massage with or without aromatherapy on infant´s level of distress
- Trial name
- aromatherapy (NCT00624637)
- Testing
- aromatherapy massage
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- Erasmus Medical Center
Cleft Palate
Timing of Primary Surgery for Cleft Palate
This trial is a randomised controlled trial with a parallel design taking place in centres across the UK, Scandinavia and Brazil.
- Trial name
- TOPS (NCT00993551)
- Testing
- primary surgery for cleft palate
- Where
- 23 sites in Brazil, Denmark and 3 more
- Volunteers
- 558 people
- Sponsor
- Kevin Munro
Cleft Palate
Cleft Palate With Intravelar Veloplasty Repair
Cleft palate repair is the most important component of cleft surgery, not only in that it determines the outcome as far as speech and communication are concerned, but also in that it potentially has the greatest impact on…
- Trial name
- NCT05196555
- Testing
- Repair of cleft palate with intravelar veloplasty (IVVP)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Hams Hamed Abdelrahman
Cleft Lip, Cleft Lip Scar
Cleft Lip Scarring After Botox
This study is investigating whether botulinum toxin type A (Botox) can improve scar appearance after cleft lip repair surgery. Cleft lip repair is commonly performed during infancy, but visible scarring can occur as the incision…
- Trial name
- CLSAB (NCT07880860)
- Testing
- Botulinum Toxin Type A (BOTOX) Injection, Normal Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's National Research Institute
Dentofacial Deformities
The Use of Bone-borne Guides in Orthognathic Surgery Cases
The present study was conducted to evaluate a new design of the intermediate stent that is used in orthognathic surgery cases requiring Le Fort I osteotomy.
- Trial name
- NCT04224805
- Testing
- Bone-borne CAD/CAM splint, 3D interocclusal conventional splint
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Maxilla; Hypoplasia
Transverse Maxillary Expansion With a Segmental Le Fort I Osteotomy or Surgically Assisted Rapid Maxillary Expansion (SARME)
To assess transverse dental and skeletal expansion and stability after SLFIO with no fixation of the palatal vault compared to stabilization of the palatal vault with an autogenous bone block graft or fixation of the palatal…
- Trial name
- NCT03511989
- Testing
- Bone borne distractor, Tooth borne distractor, Segmental LF1 Osteotomy group 1
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Cleft Palate
Retrospective Study on the Outcome of Cleft Palate Repair: Comparing US Surgical and Ethicon Suture Materials
Investigator initiated retrospective chart review to study the effects of changing suture material on the healing and outcome of cleft palate surgery were.
- Trial name
- NCT00584272
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of California, Davis
Prognathism, Retrognathia
Transoral Versus Transbuccal Placement of Bicortical Screws During Orthognathic Surgery
Bicortical screws have been widely used for mandibular osteosynthesis during orthognathic surgery.Transoral placement of bicortical screws is a rigid fixation method in orthognathic surgery, which is less often used.
- Conditions
- Prognathism, Retrognathia, Jaw Abnormalities
- Trial name
- NCT02658305
- Where
- Belgium
- Volunteers
- 509 people
- Sponsor
- AZ Sint-Jan AV
Noonan Syndrome
Link Between Abnormal Bleeding and Coagulation Disorders in Noonan Syndromes
Noonan syndrome is a relatively rare genetic disorder, affecting around 1 in every 1,000 to 2,500 children born. Patients often have a tendency to bleed more easily, particularly from the skin or mucocutaneous tissue (such as…
- Trial name
- PlatNoon (NCT07259135)
- Testing
- Reuse of routine clinical and biological data
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Bordeaux
Craniofacial Surgery
Effect of Novel High Dissolving Transitional Foods
This is a prospective comparative study, where patients who meet inclusion criteria undergoing a craniofacial procedure will either be provided with novel high dissolving transitional foods for use in the post-operative period…
- Trial name
- NCT06522958
- Testing
- High Dissolving Transitional Food
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- NYU Langone Health
Epilepsy, Focal Cortical Dysplasia
Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery
Refractory epilepsy, meaning epilepsy that no longer responds to medication, is a common neurosurgical indication in children. In such cases, surgery is the treatment of choice.
- Conditions
- Epilepsy, Focal Cortical Dysplasia, Tuberous Sclerosis, Hemimegalencephaly
- Trial name
- NCT04344626
- Testing
- Intra-operative brain tonometry
- Where
- 2 sites in United States, Canada
- Sponsor
- University of California, Los Angeles
Craniosynostoses
Clinical Feasibility Study of Preoperative Surgical Planning
Most children diagnosed with craniosynostosis undergo a relatively extensive cranial vault remodeling procedure. The decision of performing surgical cranial shape correction for patients with craniosynostosis typically rests on a…
- Trial name
- NCT03812159
- Testing
- iCSPlan
- Where
- United States
- Sponsor
- Gary F. Rogers, MD
Orthognathic Surgery, Dentofacial Deformities
Development and Validation of an Automated Three-dimensional Cephalometry Method
This study is aimed to develop and assess the validity of an algorithm for automated three-dimensional cephalometry.
- Trial name
- AutoCEPH-3D (NCT04464252)
- Where
- France
- Volunteers
- 453 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Craniotomy Surgery, Cancer
The Management of Postoperative Craniotomy Pain in Pediatric Patients
The purpose of this prospective, clinical observational trial is to assess the incidence of pain (and analgesia), methods of pain assessment (and by whom), prescribed analgesics, methods of analgesic delivery, and patient/parent…
- Conditions
- Post Craniotomy Surgery, Cancer, Epilepsy, Vascular Malformations
- Trial name
- NCT01576601
- Where
- 3 sites in United States
- Volunteers
- 81 people
- Sponsor
- Johns Hopkins University
Cleft Palate
The Role of Antibiotic Prophylaxis in Cleft Palate and Velopharyngeal Insufficiency Repair
Cleft Lip and Palate surgical repair is one of the most common procedures performed by Plastic and Reconstructive Surgeons in the World.
- Trial name
- Cleft Palate (NCT02688634)
- Testing
- Amoxicillin
- Where
- 2 sites in United States
- Sponsor
- University of Florida
Craniosynostoses
EPBONF : Evaluation of the Safety and Effectiveness of a Medical Device Aimed at Guiding Orbito-naso-frontal Band Surgery, for the Treatment of Craniostenoses
Craniostenosis is a congenital disorder caused by early fusion of the cranial sutures between the skull bones, resulting in orbito-naso-frontal deformities.
- Trial name
- EPBONF (NCT06366178)
- Testing
- BONFIX system
- Volunteers
- 5 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon