Clinical trials: Critical Limb Ischaemia
Critical Lower Limb Ischemia, Abdominal Aortic Aneurysms
The Use of Carbon Dioxide as a Contrast Media for Performing Endovascular Procedures
Prospective randomized comparison between endovascular procedures performed with iodinated contrast or carbon dioxide as intraarterial contrast.
- Trial name
- NCT01861327
- Testing
- CO2, Iodine contrast media
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Nelson Wolosker
Renal Impairment, Limb Ischemia, Critical
Ultra-low Dose Contrast for Endovascular Procedures
The purpose of this protocol is to study the safety and feasibility of using ultra-low dose iodinated contrast agent for infrainguinal endovascular revascularization procedures in patients with chronic limb-threatening lower limb…
- Trial name
- ULTRA-LOW (NCT06835127)
- Testing
- Infrainguinal peripheral endovascular revascularization
- Where
- Greece
- Volunteers
- 18 people
- Sponsor
- Attikon Hospital
Vascular Diseases, Peripheral Artery Disease
RECCORD (Recording Courses of Vascular Diseases) Registry
The RECording COurses of vasculaR Diseases registry (RECCORD registry) is an observational, prospective, multicentre, all-comers registry platform.
- Conditions
- Vascular Diseases, Peripheral Artery Disease, Claudication, Critical Limb Ischemia
- Trial name
- RECCORD (NCT03448029)
- Where
- Germany
- Volunteers
- 6,000 people
- Sponsor
- Deutsche Gesellschaft für Angiologie, Gesellschaft für Gefäßmedizin e.V.
Angioplasty, Critical Lower Limb Ischemia
Outcomes of Straight-line Flow Versus Angiosome-targeted Angioplasty in Treatment of Critical Lower Limb Ischemia
Peripheral arterial disease (PAD) affects more than 200 million people worldwide. Although over 50% are asymptomatic, it accounts for 4% of all amputations.
- Trial name
- NCT06127134
- Testing
- peripheral angioplasty for tibial vessels
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University
Chronic Limb-Threatening Ischemia
The Role of Glass Stage Compared to WIFI Stage in Predicting Limb Salvage
compare between GLASS and WIFI Staging in predicting limb salvage in patients with chronic limb threatening ischemia ( CLTI) undergoing endovascular revascularization.
- Trial name
- NCT06209866
- Testing
- PTA
- Volunteers
- 28 people
- Sponsor
- Assiut University
Sarcopenia, Peripheral Arterial Disease
Sarcopenia and Peripheral Artery Disease With Chronic Limb Threatening Ischemia
To evaluate the correlation of Sarcopenia Parameters and Peripheral Artery Disease with chronic limb threatening ischaemia.
- Conditions
- Sarcopenia, Peripheral Arterial Disease, Chronic Limb Threatening Ischemia
- Trial name
- SAC (NCT07037979)
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Fudan University
Chronic Limb-Threatening Ischemia, Colorectal Carcinoma
Comparison of Outcomes of Patients With Stage IV Chronic Limb-threatening Ischemia and Colorectal Cancer
Colorectal cancer (CRC) and chronic limb-threatening ischemia (CLTI) are relatively frequent and potentially fatal diseases. However, studies that are comparing clinical outcomes between CRC and CLTI patients in more advanced…
- Conditions
- Chronic Limb-Threatening Ischemia, Colorectal Carcinoma, Colorectal Carcinoma Metastatic in the Liver
- Trial name
- NCT05116696
- Testing
- For chronic limb-threatening ischemia (CLTI) patients revascularisation surgery; for colorectal liver metastasis (CRLM) patients metastatic liver surgery
- Where
- Serbia
- Volunteers
- 836 people
- Sponsor
- Clinical Centre of Serbia
Peripheral Arterial Disease, Rutherford 4 and 5 With Possibility to Improve Vascularization
Exercise Therapy With Risk Factor Management and Life Style Coaching After Vascular Intervention for Patients With Peripheral Arterial Disease
Patients with peripheral arterial disease with symptoms of critical ischemia or reduced tissue loss have a very high mortality and morbidity rate.
- Trial name
- PEARL (NCT02110251)
- Testing
- Supervised Exercise Therapy
- Where
- 2 sites in Netherlands
- Volunteers
- 14 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
COVID, Critical Limb Ischemia
The Impact of COVID-19 Pandemic on Critical Limb Threatening Ischemia and Emergency Vascular Practice
This is a retrospective analytical study conducted at Vascular and Endovascular surgery Department, Mansoura University Hospital, including all patients admitted at the two periods first six months of 2019 and 2020.To demonstrate…
- Trial name
- NCT04452682
- Testing
- COVID 19 impact
- Where
- Egypt
- Volunteers
- 998 people
- Sponsor
- Mansoura University
Peripheral Arterial Disease, Critical Limb Ischemia (CLI)
Pressure (Fractional Flow Reserve) and Flow (Vascular Flow Reserve) Measurements During Peripheral Arterial Interventions
Fractional Flow Reserve (FFR) and Coronary Flow Reserve (CFR) have been originally developed for physiological assessment of coronary artery disease and may hold potential in the management of Peripheral Arterial Disease (PAD) as…
- Trial name
- FLOW-PAD (NCT07052435)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Dr. Konstantinos Katsanos
Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities
GLASS Classification and CLTI
Critical limb threatening ischemia "CLTI 'is not a separate local disease but also it is a part of generalized vascular disorder.
- Trial name
- NCT05209672
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Assiut University
Critical Limb Ischemia, Arterial Occlusive Disease
Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemia
The hypothesis behind the trial is the concept that Pregabalin is effective in reducing pain at rest in lower limb ischemia, and the study evaluates active treatment or placebo added to the regular pain regimens for these…
- Conditions
- Critical Limb Ischemia, Arterial Occlusive Disease, Pain, Ischemia
- Trial name
- NCT00403780
- Testing
- pregabalin
- Where
- 3 sites in Sweden
- Volunteers
- 18 people
- Sponsor
- Karolinska Institutet
Critical Limb Ischemia
Prospective Observation Study of Outcome of Interventions for Critical Ischemia
Severe atherosclerosis in the leg arteries is termed critical limb ischemia (CLI). This condition gives great suffering for the patients in terms of pain, wounds and often developing gangrene.
- Trial name
- PROVENCE (NCT01794494)
- Testing
- Bypass surgery, Endovascular recanalization
- Where
- Sweden
- Volunteers
- 190 people
- Sponsor
- Sahlgrenska University Hospital
Wound Heal, Duplex Volume Flow
Correlation Between the Volume Flow of the CFA After Angioplasty of Critical Ischemic Limb and Wound Healing
in our study we are examining the volume flow of the common femoral artery before and after angigraphy of a critical ischemic limb, as a predictor for wound healing after the treatment
- Trial name
- NCT04672668
- Testing
- duplex ultrasound for the common femoral artery
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
End-stage Renal Disease, Critical Limb Ischemia
Open Versus Endovascular Revascularization in Patients With End-stage Renal Disease
Treatment of patients with end-stage renal disease and critical limb ischemia still poses challenges to vascular medicine due to limited survival, comorbidities and infrapopliteal involvement of arteriosclerosis in these…
- Trial name
- OERESRD (NCT03293589)
- Testing
- open revascularization, endovascular revascularization
- Where
- Germany
- Volunteers
- 77 people
- Sponsor
- University Hospital Erlangen
Critical Limb Ischemia
Study of the Clinical Efficacy of Autologous SCT in Patients With Critical Limb Ischemia
Phase II Prospective Study of the Clinical Efficacy of Autologous SCT in patients with Critical Limb Ischemia
- Trial name
- NCT01311011
- Testing
- SCT
- Where
- Saudi Arabia
- Volunteers
- 26 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Critical Limb Ischemia
Autologous Angiogenic Cell Precursors (ACPs) for the Treatment of Peripheral Artery Disease
Regeneration of the occluded peripheral arteries by autologous stem cell therapy is an emerging treatment modality for no-option patients with peripheral artery disease (PAD).
- Trial name
- NCT01584986
- Testing
- ACP injections
- Where
- 2 sites in Hungary
- Volunteers
- 22 people
- Sponsor
- Salus Ltd.
Stroke
Evaluation of Diagnostic Criteria for Chronic Critical Limb Ischemia
Chronic critical limb ischemia (CCI) is the most severe clinical form of occlusive arterial disease. Its prognosis is terrible, mortality estimated at 50% in five years.
- Trial name
- CRIMI (NCT02834143)
- Testing
- No intervention
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Peripheral Arterial Disease, Critical Limb Ischemia
Tibiopedal Access for Crossing of Infrainguinal Artery Occlusions
The objective of this prospective, non-randomized, multicenter, post-market, observational study is to compile clinical data on percutaneous techniques used to obtain tibiopedal access and to cross infrainguinal arterial…
- Trial name
- NCT01609621
- Testing
- Retrograde tibiopedal arterial access
- Where
- 11 sites in United States, Germany and 1 more
- Volunteers
- 199 people
- Sponsor
- Cook Group Incorporated
Critical Limb Ischemia
Study to Explore the Effect of Lowering Blood Viscosity in Patients With Treatment-resistant Critical Limb Ischemia
PAD is caused by an increased flow resistance in atherosclerotic ischemic limbs. The investigators hypothesize that reducing blood viscosity (through controlled phlebotomy), thereby increasing the deformability of red blood…
- Trial name
- CLI-PH (NCT01758874)
- Testing
- phlebotomy
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul Veterans Hospital