Clinical trials: Critically Ill Intensive Care Unit Patients
Critical Illness, Pneumonia, Viral
Comparison Between Different Doses of Steroids in COVID-19 Patients
aim of this study is to compare between standard dose methyl prednisolone and mega dose methyl prednisolone as regards outcome reflected by mortality rate, percentage of mechanically ventilated patients and icu length of stay of…
- Trial name
- COVID-19 (NCT05279482)
- Testing
- observation for outcome of methylprednisolone dose
- Where
- 2 sites in Egypt
- Volunteers
- 104 people
- Sponsor
- Ain Shams University
Covid19, Critically Ill
Risk Factors for Mortality for COVID-19 Admitted to an Intensive Care Unit
Studying clinical characterization of critically ill COVID-19 patients in a single center Studying Risk factors for Day 28 Mortality in COVID-19 patients admitted to intensive care unit
- Trial name
- ICUCOVID-KK (NCT04805645)
- Testing
- No intervention (Retrospective Cohort Observational)
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- Clinical Research Centre, Malaysia
Secondary Hypothyroidism
Thyroid Function in Critically Ill Patients With Acute Kidney Injury
The objective of this study was to assess the changes in thyroid hormones and its activity during CRRT in patients with Acute Kidney Injury.
- Trial name
- NCT04767763
- Testing
- Assessment of TSH, fT3, fT4,TRH, TT3, TT4, rT3 in patients with CVVHDF
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- Medical University of Gdansk
Critical Illness, Post Intensive Care Unit Syndrome
pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS
The goal of this multi-site observational study is to compare delirium rates, days on mechanical ventilation, and Post Intensive Care Syndrome (PICS) rates in adult Intensive Care Unit (ICU) patients.
- Conditions
- Critical Illness, Post Intensive Care Unit Syndrome, Post Intensive Care Syndrome, Mechanical Ventilation Complication
- Trial name
- NCT06019078
- Testing
- SedLine
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Fraser Health
Critically Ill
Towards RECOVER: Outcomes and Needs Assessment in Intensive Care Unit (ICU) Survivors of Prolonged Mechanical Ventilation and Their Caregivers
Advances in critical care medicine have dramatically improved the survival of critically ill patients requiring prolonged mechanical ventilation.
- Trial name
- RECOVER (NCT00896220)
- Where
- 5 sites in Canada
- Volunteers
- 500 people
- Sponsor
- University Health Network, Toronto
Critical Illness, Hyperglycemia
Tight Glycemic Control in Critical Care Patients
The purpose of this study is to evaluate the impact of tight control of serum glucose levels with an intensive insulin treatment in patients hospitalized in an intensive care unit with medical and surgical patients.
- Conditions
- Critical Illness, Hyperglycemia, Insulin Resistance
- Trial name
- NCT00096421
- Testing
- Tight control of blood glucose levels, Conventional control of glucose levels
- Where
- Colombia
- Volunteers
- 504 people
- Sponsor
- Hospital Pablo Tobón Uribe
Critical Illness, Safety Issues
TraceBook: the Clinical Proof of Concept on the Intensive Care.
The effectiveness of current checklists is hampered by lack of acceptance and compliance. Recently, a new type of checklist with dynamic properties has been created to provide more specific checklist items for each individual…
- Trial name
- TraceBook (NCT03599856)
- Testing
- TraceBook
- Where
- Netherlands
- Volunteers
- 408 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Oral Bacterial Colonization, Oral Hygiene
Effects of Three Oral Hygiene Protocols on Oral Bacteria in Intensive Care Patients
Patients in intensive care may develop changes in the bacteria found in their mouths. Some of these bacteria can cause infections, and patients who cannot clean their own teeth depend on staff to provide oral care.
- Trial name
- NCT07868549
- Testing
- Mechanical Oral Hygiene, Chlorhexidine, Hexetidine
- Where
- Croatia
- Volunteers
- 86 people
- Sponsor
- University of Zagreb
Metabolic Acidosis, Acid-Base Imbalance
Frequency of Metabolic Acidosis in the Pediatric Intensive Care Unit
Metabolic acidosis is one of the most common acid-base disturbances encountered in critically ill children and often reflects underlying disease severity.
- Conditions
- Metabolic Acidosis, Acid-Base Imbalance, Critical Illness in Children
- Trial name
- NCT07803263
- Volunteers
- 140 people
- Sponsor
- Assiut University
Vascular Access Devices
Effect of Education of Health Care Workers on the Maintenance of Venous Access Devices
In intensive care units (ICU), critically ill patients require various venous access devices for fluid resuscitation, drug therapy, or renal replacement therapy (RRT).
- Trial name
- NCT04692753
- Testing
- Training and education
- Where
- India
- Volunteers
- 400 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Critical Illness, Sepsis
Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients
Introduction- Hospital acquired infections (HAI) are a major cause of morbidity and mortality and increase health care costs. Critically ill patients are particularly susceptible to these infections and have an even higher…
- Conditions
- Critical Illness, Sepsis, Septic Shock, Ventilator Associated Pneumonia
- Trial name
- SuDDICU (NCT02389036)
- Testing
- SDD Oral Paste, SDD Gastric Suspension, Intravenous Antibiotic
- Where
- 3 sites in Australia, Canada and 1 more
- Volunteers
- 20,010 people
- Sponsor
- The George Institute
Severe Malnutrition
Management and Treatment of Patients With Severe Malnutrition in Intensive Care Unit: a Registry
Severe malnutrition can be seen as a low BMI, great weight loss, and even low levels of micronutrients. Current studies on severe malnutrition are mainly in patient with anorexia nervosa.
- Trial name
- NCT03055104
- Testing
- management of severe malnutrition
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University Third Hospital
Multi-resistant Gram-negative Bacteria Cause Infection
GRAM NEGATIVES STUDY
This is a prospective, observational, multicenter study whose main objective is to develop a predictive model of mortality in critically ill patients colonized by multidrug-resistant Gram-negative bacteria (MDR-GNB).
- Trial name
- MR-GEIPC (NCT07749508)
- Testing
- Standard of care therapy
- Where
- Spain
- Volunteers
- 1,500 people
- Sponsor
- Fundacion SEIMC-GESIDA
Enteral Nutrition, Enteral Nutrition Feeding
Stepwise Enteral Nutritional Algorithm and Patient Outcomes in Pediatric Intensive Care Units
The aim of the study to evaluate the effectiveness and patient's outcome after implementing enteral nutrition algorithm designed to achieve optimal enteral nutrition delivery in the pediatric intensive care unit and to evaluate…
- Conditions
- Enteral Nutrition, Enteral Nutrition Feeding, Enteral Nutrition Intolerance in Critically Ill Patients
- Trial name
- NCT07307027
- Testing
- Stepwise Enteral Nutritional Algorithm
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Muscle Weakness, Critical Illness
Critical Illness Neuromuscular Abnormalities in Neurocritical Care Patients
The aim of this research is to investigate critical illness neuromuscular abnormalities in neurocritical care patients.
- Trial name
- NCT00893633
- Where
- Russia
- Volunteers
- 135 people
- Sponsor
- Clinical Institute of the Brain, Russia
Liver Transplantation, Infection
Italian National Study on the Critically Ill Liver Transplant Patient With an Infection
Despite major advances, infections remain one of the major causes of morbidity and mortality in patients undergoing orthotopic liver transplantation (OLT).
- Conditions
- Liver Transplantation, Infection, Sepsis, Intensive Care Unit
- Trial name
- INFE-OLT (NCT03363646)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Sepsis
Efficacy and Safety of a Multicomponent Physical Therapy Program in Mechanically Ventilated Patient With Sepsis
Despite of a remarkable decrease in overall mortality has been achieved following the International Guidelines for Management of Sepsis and Septic Shock since 2004,the short-and long-term outcomes remain poor in critically ill…
- Trial name
- PTMVP (NCT03406494)
- Testing
- Early multicomponent physical therapy program
- Volunteers
- 800 people
- Sponsor
- Zhujiang Hospital
Critical Illness
European Mortality & Length Of Intensive Care Unit (ICU) Stay Evaluation (ELOISE)
The starting point of ELOISE is the significant number of Intensive Care Unit (ICU) survivors who die after the transfer to ward.
- Trial name
- ELOISE (NCT01422070)
- Where
- Italy
- Volunteers
- 6,433 people
- Sponsor
- Università degli Studi di Ferrara
Critical Illness, Children
Early Versus Late Parenteral Nutrition in the Pediatric Intensive Care Unit
In the PEPaNIC trial it is investigated whether withholding parenteral nutrition during the first week in critically ill children is beneficial, compared to the current standard of the early start of parenteral nutrition.
- Trial name
- PEPaNIC (NCT01536275)
- Testing
- Late parenteral nutrition
- Where
- 3 sites in Belgium, Canada and 1 more
- Volunteers
- 1,440 people
- Sponsor
- KU Leuven
Terminally Ill Patients
Mobile Shared Decision-Making Program for ICU Caregivers
By developing a smart mobile shared decision-making (SDM) model, this study aims to assist family members of critically ill end-stage patients in making appropriate decisions, enhance their decision quality, and evaluate the…
- Trial name
- NCT07469878
- Testing
- Experimental: Mobile technology devices
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- CHIA-HUI MA