Clinical trials: Critically- Ill Children
Pediatric Intensive Care Units
Nutritional Status of Critically Ill Children in Pediatric Intensive Care Units at Sohag University Hospitals
The goal of this observational study is to evaluate nutritional status of critically ill patients admitted to Pediatric Intensive Care Units (PICU) at Sohag University Hospital and its correlation with their outcome as regarding…
- Trial name
- NCT07041658
- Volunteers
- 100 people
- Sponsor
- Sohag University
Sedation Complication
Validation of a Processed EEG Device for Monitoring Sedation in PICU
The goal of this prospective observational study is to validate pEEG as a monitoring tool for the analgosedation level in mechanically-ventilated critically ill children, receiving or not-receiving NMBAs.
- Trial name
- NCT05969483
- Testing
- pEEG monitoring
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliera di Padova
Seizures
Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children
Electrographic seizures are common in critically ill patients leading to increased use of resource-intense continuous EEG monitoring for seizure identification and management.
- Trial name
- NCT03419260
- Testing
- Clinically indicated EEG monitoring.
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Children's Hospital of Philadelphia
Gastrointestinal Manifestations in Critically Ill Children
Gastrointestinal Manifestations in Critically Ill Children Admitted in PICU of Children's Hospital Assuit University
Gastrointestinal complications are common in critically ill children. GIC are commonly observed, as either a primary reason for admission or as a part of multiple organ dysfunction syndromes MODS in children admitted in the…
- Trial name
- NCT06235528
- Volunteers
- 83 people
- Sponsor
- Assiut University
Critical Illness
Lorazepam Sedation for Critically Ill Children
This clinical trial is being performed under the Best Pharmaceuticals for Children Act, signed into law in 2002 in order to improve pediatric labeling for off-patent drugs.
- Trial name
- NCT00109395
- Testing
- Lorazepam, Midazolam, Lorazepam CI
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- The Emmes Company, LLC
Music Therapy, Critical Care
Music Use for Sedation In Critically Ill Children
Stress induced by pain and anxiety is common in pediatric intensive care unit (PICU) patients and can impede the delivery of care as well as their recovery.
- Conditions
- Music Therapy, Critical Care, Analgesia, Ventilators, Mechanical
- Trial name
- MUSiCC (NCT03497559)
- Testing
- Music
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Acute Gastrointestinal Injury, Gastrointestinal Failure
Acute Gastrointestinal Injury in Pediatrics
Critically Ill children may develop acute gastrointestinal injury secondary to severe inflammation.
- Conditions
- Acute Gastrointestinal Injury, Gastrointestinal Failure, Critical Illness
- Trial name
- AGI (NCT05315245)
- Testing
- AGI
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Universitas Indonesia
Critical Illness
Improving Outcomes After PICU Admission: A Pilot Study
1. Evaluate the feasibility and acceptability of an information based intervention delivered to parents following their child's admission to paediatric intensive care; 2.
- Trial name
- NCT01737021
- Testing
- Psycho-education
- Volunteers
- 31 people
- Sponsor
- Imperial College London
Child, Critical Illness
Measuring the Metabolic Cost of Fever
Fever is part of the body's immune response, often triggered by infection. Fever is commonly treated with medicines such as paracetamol, mainly because people feel unwell with fever.
- Conditions
- Child, Critical Illness, Fever
- Trial name
- IGUANA (NCT02939781)
- Testing
- Indirect calorimetry
- Volunteers
- 12 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Iohexol, Pharmacokinetics
Renal Function Assessment in Critically Ill Children
Identification of renal dysfunction in critically ill children is often delayed due to lack of accurate methods for evaluation of glomerular filtration rate (GFR).
- Conditions
- Iohexol, Pharmacokinetics, Renal Function, Critically Ill Children
- Trial name
- IOHEXOL (NCT05179564)
- Testing
- iohexol administration, iohexol blood sampling
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Critical Illness, Children
Functional Recovery in Critically Ill Children
Intensive Care Unit-acquired weakness (ICU-AW) is a well-recognized, important and preventable sequelae of critical illness, affecting up to 60% of adult ICU patient.
- Trial name
- NCT01724593
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Karen Choong
Critically Ill
Improving Sleep in the Pediatric Intensive Care Unit
Sleep is disrupted in the PICU. This disruption has been reported in studies that have used: (a) observation of sleep-wake cycles (b) self-reports by children themselves , and (c) objective measures (e.g., electroencephalograph…
- Trial name
- NCT00178321
- Testing
- earplugs
- Where
- United States
- Sponsor
- University of Rochester
Renal Angina, Acute Kidney Injury
Study of the Prediction of Acute Kidney Injury in Children Using Risk Stratification and Biomarkers
Acute kidney injury (AKI) is a common clinical event with severe consequences. In the pediatric intensive care unit (PICU), AKI occurs in almost 10% of all patients and evidence suggests that children are dying not just with AKI…
- Trial name
- AKI-CHERUB (NCT01735162)
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Critical Illness
Effects of Daily Interruption of Sedatives in Critically Ill Children
Critically ill children are often sedated in order to relieve them from anxiety and discomfort, and to facilitate their care. There is little information on the effects of prolonged and continuous use of sedatives and analgesic…
- Trial name
- NCT00441506
- Testing
- daily interruption of sedatives
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Intensive Care
Measurement of Cardiac Output and Intravascular Volume Status in Children Using COstatus (SH)
Assessment and monitoring of cardiac function in the pediatric intensive care unit (PICU) is an integral part of hemodynamic monitoring of critically ill patients whether it is done directly or indirectly.
- Trial name
- NCT01613859
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Transonic Systems Inc.
PTSD, Critical Illness
The Experiences of Children and Caregivers Given PICU Storybooks
1. To assess the acceptability and feasibility of a study design aimed at evaluating the efficacy of a newly developed intervention for children and their caregivers following discharge from PICU 2.
- Conditions
- PTSD, Critical Illness, Depression, Anxiety
- Trial name
- NCT04041401
- Testing
- PICU storybook
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Catheter Complications, Critical Illness
"Syringe Free" Long-Axis In-Plane vs. Short-Axis Out-of-Plane Approach for Central Venous Catheter Placement
Internal jugular, subclavian, or femoral veins are often used for central venous catheter (CVC) placement. Regardless of which vein is preferred, the "Seldinger" technique is used most frequently.
- Trial name
- NCT04684069
- Testing
- Long-axis syringe free in-plane, Short-axis out-of-plane
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Bed Sore, Pressure Ulcer
Use of Honey for Pressure Ulcers in Critically Ill Children
The enrolled children would be randomized to one of the groups 'study group' or 'Honey dressing group' or 'Group I' (honey dressing containing Active Leptospermum Honey also known as Manuka honey would be used), changed every…
- Conditions
- Bed Sore, Pressure Ulcer, Pressure Sore, Critically Ill Children
- Trial name
- NCT03391310
- Testing
- Honey (medicated)
- Where
- 2 sites in India
- Volunteers
- 100 people
- Sponsor
- All India Institute of Medical Sciences
Child, Only, Infant, Newborn, Diseases
Capnography Monitoring in Ventilated Children
End-tidal CO2 measurements in children will be assessed for their accuracy with arterial CO2 measurements.
- Conditions
- Child, Only, Infant, Newborn, Diseases, Critical Illness, ARDS, Human
- Trial name
- NCT04354220
- Testing
- capnography monitoring, arterial blood gas
- Where
- Switzerland
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Vincenzo Cannizzaro
Pediatric ALL, Critical Illness
Singapore's Health Outcomes After Critical Illness in Kids
What is the problem? Every year about 2.5 million children are affected by critical illness and require admission to the pediatric intensive care unit (PICU).
- Conditions
- Pediatric ALL, Critical Illness, Post Intensive Care Unit Syndrome
- Trial name
- SHACK (NCT04637113)
- Testing
- This is a non-interventional study
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital