Clinical trials: Cross Infection
Neonatal Infection
Effect of Chlorhexidine Versus Alcohol on Infections in Neonates
Chlorhexidine is a local antiseptic that has an important role in the prevention of catheter-associated bloodstream infections. Its application to a newborn's umbilical cord reduces all-cause neonatal mortality.
- Trial name
- NCT06194396
- Testing
- chlorhexidine, alcohol
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
HIV Infections
Sexual Health Advocacy for Guys - a Text Messaging-based HIV Prevention Program for Guys Who Are Into Guys
SHAG is a text messaging-based HIV prevention program designed for cisgender sexual minority boys and men 13-20 years of age across the United States.
- Trial name
- SHAG (NCT06230367)
- Testing
- Sexual health advocacy for guys, Healthy lifestyle control
- Where
- 2 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Center for Innovative Public Health Research
Respiratory Syncytial Virus (RSV) Infection, Acute Lower Respiratory Tract Infections
Assessing the Burden of Respiratory Syncytial Virus (RSV)
This study examines the impact of Respiratory Syncytial Virus (RSV) on people of all ages, from infants to the elderly. It uses hospital records collected between January 2018 and December 2024 to understand: How often does RSV…
- Conditions
- Respiratory Syncytial Virus (RSV) Infection, Acute Lower Respiratory Tract Infections, Bronchiolitis, Pneumonia
- Trial name
- NCT07015255
- Where
- United Arab Emirates
- Volunteers
- 1,500 people
- Sponsor
- Abu Dhabi Health Services Company
Nosocomial Pneumonia
Safety and Pharmacokinetics of Ceftolozane/Tazobactam in Pediatric Participants With Nosocomial Pneumonia (MK-7625A-036)
This is a phase 1, open-label, non-comparative, multicenter clinical study to evaluate the safety, tolerability, and pharmacokinetics of ceftolozane/tazobactam (MK-7625A) in pediatric participants with nosocomial pneumonia (NP).
- Trial name
- NCT04223752
- Testing
- Ceftolozane/Tazobactam
- Where
- 24 sites in United States, Chile and 7 more
- Volunteers
- 41 people
- Sponsor
- Merck Sharp & Dohme LLC
HIV/AIDS, Gender
Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - Intervention Development
To address the critical scientific gaps in PrEP safety for transgender youth and to plan for appropriate implementation of PrEP in transgender youth communities, the study will be conducted in 3 integrated phases.
- Conditions
- HIV/AIDS, Gender, Behavior and Behavior Mechanisms
- Trial name
- NCT04077138
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
Influenza, Respiratory Tract Infections
Patient Portal Flu Vaccine Reminders (5)
This trial is taking place in Los Angeles, CA at clinics within the UCLA Health System. The study design is a 2x2 nested factorial design.
- Trial name
- NCT05525494
- Testing
- Text Fixed R/R Messages with Direct Appointment Schedule Link, Text Pre-Appointment Reminder, Portal Pre-Commitment Prompt with Tailored R/R Messages with Direct Appointment Schedule Link
- Where
- United States
- Volunteers
- 262,085 people
- Sponsor
- University of California, Los Angeles
Congenital Cytomegalovirus Infection
A Cross-sectional Study of Congenital Cytomegalovirus Infection in Newborns in China
The primary objectives of this study were to evaluate the incidence of congenital CMV infection in neonates, and assess the concordance of detecting congenital cytomegalovirus (CMV) infection in neonatal saliva and urine samples.
- Trial name
- NCT02710864
- Where
- 4 sites in China
- Volunteers
- 1,510 people, healthy volunteers welcome
- Sponsor
- Jun Zhang
Monkeypox (Mpox)
Epidemiological and Pathophysiological Insights Through a Cross-sectional Survey (EPIC)
This study aims to better understand how mpox is spreading in the DRC, how it affects different groups of people, and how well vaccines protect against it.
- Trial name
- MBOTE-EPIC (NCT06840860)
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 1,000 people
- Sponsor
- Institute of Tropical Medicine, Belgium
COVID19
Part 2 on the Study Prevalence of SARS -Cov2 Carriage in Asymptomatic and Mildly-symptomatic Children (COVILLE2) (WHO)
France and in particular the paris area was one of the countries most affected by the pandemic Covid19. School closures and a generalized lockdown of the population were instituted in France from 17 March 2020 to 10 May 2020.
- Trial name
- COVILLE2 (NCT04416893)
- Testing
- RT-PCR SARS-Cov2, Sars-Cov2 serology
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Mycoses, Leukemia
Assessment of the Fungal Infection Incidence Across Canada for High Risk Participants With Hematological Disease (P07501)
This will be a retrospective study that includes retrospective chart reviews at major institutions across Canada. The intent of the study is to generate both regional and national incidence data for non-Candida invasive fungal…
- Trial name
- TRAFIC (NCT01254318)
- Testing
- Standard Care
- Volunteers
- 130 people
- Sponsor
- Merck Sharp & Dohme LLC
Nosocomial Infections, Sepsis
Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants
The purpose of this study is to show whether Veronate, a donor-selected staphylococcal human immune globulin intravenous (IGIV), can prevent an infection in the blood caused by staphylococcal bacteria in premature babies weighing…
- Conditions
- Nosocomial Infections, Sepsis, Staphylococcal Infections, Candidemia
- Trial name
- NCT00113191
- Testing
- Veronate
- Where
- 93 sites in United States, Canada
- Volunteers
- 2,000 people
- Sponsor
- Bristol-Myers Squibb
Nosocomial Infection, Infection Control
Can Environmental Cleanliness be Assessed by BCA (Bicinchoninic Acid) Method
Effective cleaning of surfaces in the hospital environment is an absolute necessity to reduce pathogen transmission. Multi Drug Resistant Organisms (MDRO) in ICU are among the leading causes of hospital-acquired infections.
- Conditions
- Nosocomial Infection, Infection Control, Multi-antibiotic Resistance
- Trial name
- BCA (NCT04212130)
- Testing
- BCA method for assessing environmental cleanliness
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cumhuriyet University
Ventilator Associated Pneumonia, Antibiotic Resistant Infection
Ceftolozane-tazobactam for the Treatment of Respiratory Infections Due to Extensively Drug-resistant Pseudomonas Aeruginosa Among Critically Ill Patients: a Retrospective Study.
The aim of this study is to report our experience with ceftolozane-tazobactam and to evaluate its safety and efficacy in the treatment of ICU dependent nosocomial respiratory tract infections due to extensively drug resistant…
- Trial name
- NCT04352855
- Testing
- Ceftolozane/tazobactam
- Where
- Hungary
- Volunteers
- 55 people
- Sponsor
- Semmelweis University
Tuberculosis, Pediatric
TB Innovation Project: A Pre- and Post- Implementation Assessment (TIPPI)
This evaluation will be conducted in ten countries involved in the Catalyzing Pediatric TB Innovation (CaP-TB) project: Cameroon, Cote D'Ivoire, Democratic Republic of Congo, Kenya, Lesotho, Malawi, Tanzania, Uganda, Zimbabwe and…
- Trial name
- TIPPI (NCT03948698)
- Testing
- Innovative approached to pediatric TB care
- Where
- 10 sites in Cameroon, Côte d’Ivoire and 8 more
- Volunteers
- 4,159,533 people
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Nosocomial Infections
Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality
This 4-year cluster randomized controlled trial aims to determine whether implementation of Evidence-based Practice for Improving Quality (EPIQ) method can reduce hospital-acquired infection in Chinese Neonatal Intensive Care…
- Trial name
- NCT02600195
- Testing
- Evidence-based Practice for Improving Quality (EPIQ) method
- Where
- 24 sites in China
- Volunteers
- 15,600 people
- Sponsor
- Children's Hospital of Fudan University
HIV, Chlamydia
National Rapid TLC: Testing and Linkage to Care
The goal of this cross-sectional study is to learn if the GeneXpert system is a practical system for HIV and STBBI testing in community-based organizations and health clinics.
- Conditions
- HIV, Chlamydia, Gonorrhea, HCV
- Trial name
- NCT07730801
- Testing
- Xpert® HIV-1 Qual XC
- Where
- 2 sites in Canada
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Psychiatric Disorder, Eating Disorders in Adolescence
Recrudescence of Eating Conduct Disorders and Covid-19
This qualitative study, combining psychiatric and anthropological perspectives, focused on the development and/or worsening of patients' eating disorders since Covid-19, as well as the experiences and perceptions of those around…
- Conditions
- Psychiatric Disorder, Eating Disorders in Adolescence, COVID-19
- Trial name
- TCA-Covid19 (NCT05780242)
- Testing
- Self-questionnaire Eating Attitudes, Situational Anxiety and Trait Anxiety, Beck Depression Inventory (BDI) scale
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Fondation Lenval
Covid19
Prevalence of SARS -Cov2 Carriage in Asymptomatic and Mildly-symptomatic Children
This study is expected to provide, for the first time, data on Cov2-SARS circulation in asymptomatic children and children with moderate respiratory symptoms in order to construct the severity pyramid of this novel pathogen.
- Trial name
- COVILLE (NCT04318431)
- Testing
- Data collection and rhinopharyngeal swab
- Where
- 22 sites in France
- Volunteers
- 605 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Healthcare Associated Infection
Monitors to Improve Indoor Carbon Dioxide (CO2) Concentrations in the Hospital
Ventilation with fresh outdoor air has recently gained considerable attention as a means to reduce the potential risk of indoor aerosol transmission of respiratory pathogens such as severe acute respiratory syndrome coronavirus 2…
- Trial name
- MICH (NCT04770597)
- Testing
- Aranet4 Home CO2 monitor
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Imelda Hospital, Bonheiden
Nosocomial Infection, Necrotizing Enterocolitis
Effect of Oral Probiotic Supplementation on The Rate of Hospital Acquired Infection and Necrotizing Enterocolitis in Preterm Very Low Birth Weight Infants
The purpose of this study is to determine whether oral probiotic supplementation could reduce the incidence of nosocomial infections in preterm infants.
- Trial name
- NCT01340469
- Testing
- probiotics
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- King Chulalongkorn Memorial Hospital