Clinical trials: DVT
Childhood Cancer, Central Venous Catheters
Identification and Treatment of Clinically Silent Catheter-Related Deep Vein Thrombosis in Children With Cancer
The primary hypothesis of this study is that occult catheter-related DVT in children with cancer is common and directly contributes to development of serious catheter complications, specifically bacteremia/fungemia and/or…
- Conditions
- Childhood Cancer, Central Venous Catheters, Deep Vein Thrombosis, Catheter-related Infection
- Trial name
- DVT (NCT00633061)
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Texas Southwestern Medical Center
Deep Venous Thrombosis
The UNBLOCK Study: Utilization of Bivalirudin On Clots in Kids
Thrombosis is a significant medical complication in children with chronic diseases. The currently utilized treatments have many drawbacks which can lead to poor outcomes.
- Trial name
- UNBLOCK (NCT00812370)
- Testing
- Bivalirudin
- Where
- 6 sites in United States
- Volunteers
- 18 people
- Sponsor
- Children's Hospital Los Angeles
Pulmonary Embolism, Deep Vein Thrombosis
Non-Interruptive Alerts for Improving Use of Clinical Decision Rules
This study is an extension of a planned quality improvement project that aims to promote standard of care by increasing the use of evidence-based clinical decision rules amongst emergency medicine providers in the University of…
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Minor Head Injury, Chest Pain
- Trial name
- NCT04702308
- Testing
- Clinical Decision Rule Alerts
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Utah
Venous Thromboembolism
Study of Venous Thromboembolism Risk Profiles and Prophylaxis in Neurosurgical Inpatients
Venous thromboembolism (VTE), comprising deep venous thrombosis (DVT), pulmonary embolism (PE), or both, is a life-threatening complication in postoperative patients.
- Trial name
- VTE (NCT04257305)
- Where
- China
- Volunteers
- 9,010 people
- Sponsor
- Huashan Hospital
Deep Venous Thrombosis
Measurement of D-Dimer Levels in Patients With Confirmed Deep Vein Thrombosis
Measurement of D-Di (D-Dimer) levels using the in-vitro diagnostic reagent STA® - Liatest® D-Di and STA® - Liatest® D-Di PLUS in plasma samples from patients diagnosed with Deep Vein Thrombosis (DVT) Data from this study may be…
- Trial name
- NCT02078154
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Diagnostica Stago
Venous Thromboembolic Diseases
Comparison of 2 Low Molecular Weight Heparin as a Thromboprophylaxis Postpartum
The use of a new generation low molecular weight heparin (Bemiparin)and the well known LMWH (Enoxaparin) after Caesarean sections and vaginal deliveries in a risky group patients for venous thrombosis.
- Trial name
- NCT01588171
- Testing
- Bemiparin, Enoxaparin
- Where
- Iraq
- Volunteers
- 7,020 people
- Sponsor
- Hawler Medical University
Acute Lymphoblastic Leukemia, Post Thrombotic Syndrome
Post-thrombotic Syndrome After Deep Venous Thrombosis (DVT) in Patients Treated According to the NOPHO ALL2008 Protocol
Acute lymphoblastic leukemia (ALL) is the most common malignant disease in childhood. Today more than 90% of children and 75% of adults (18-45 years) survive ALL.
- Trial name
- NCT04825548
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Embolism, Thrombophlebitis
Treatment for Blood Clots in the Veins of the Legs
Acute deep venous thrombosis (ADVT) of the lower extremity is a common disorder. Traditional treatment with anticoagulation therapy is effective in reducing the associated risk of pulmonary embolism, but is ineffective in…
- Trial name
- NCT00001713
- Testing
- Recombinant Tissue Plasminogen Activator, Heparin, Warfarin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections
Ontario ICU Clinical Best Practices Demonstration Project
The pragmatic issue at hand how to get physicians and nurses to use best practices… and how to measure consequences of their implementation.
- Conditions
- Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections, Pressure Ulcer Prophylaxis, DVT Prophylaxis
- Trial name
- NCT00332982
- Testing
- Focused knowledge translation strategies
- Where
- Canada
- Sponsor
- Sunnybrook Health Sciences Centre
Thromboembolic Complications
Thrombelastography Based Dosing of Enoxaparin
The risk of developing a blood clot occurs in up to 60% of all critical care patients. Many times enoxaparin (or Lovenox®) is given to patients who are at a higher risk of developing clots in their legs or lungs.
- Trial name
- NCT00990236
- Testing
- Enoxaparin dose adjusted Lovenox based on TEG, Enoxaparin 30 mg BID
- Where
- 3 sites in United States
- Volunteers
- 185 people
- Sponsor
- Oregon Health and Science University
Thrombosis, Heparin-induced Thrombocytopenia
Pilot Dose Finding and Pharmacokinetic Study of Fondaparinux in Children With Thrombosis
This study will evaluate the use of a blood thinner, fondaparinux, which is approved for use in adults (not in children) in a children aged 1-18 years.
- Trial name
- NCT00412464
- Testing
- Fondaparinux
- Where
- 4 sites in United States
- Volunteers
- 24 people
- Sponsor
- Children's Hospital Los Angeles
Deep Vein Thrombosis
Safety and Efficacy Study of OmniWave Endovascular System to Treat Deep Vein Thrombosis
This is a prospective, multi-center single arm registry to assess the use of the OmniWave Endovascular System in subjects presenting with either lower or upper extremity acute (symptoms have been present for greater than or equal…
- Trial name
- SONIC I (NCT00640731)
- Testing
- OmniWave Endovascular System
- Volunteers
- 50 people
- Sponsor
- OmniSonics Medical Technologies, Inc.
Deep Vein Thrombosis
Full-Leg vs Below-Knee Elastic Stockings for Prevention of the Post-Thrombotic Syndrome
Prospective controlled randomized clinical trial. Consecutive patients with acute proximal deep vein thrombosis of the lower extremities, with or without contemporary manifestations of pulmonary embolism, are randomized to…
- Trial name
- NCT00426075
- Testing
- Elastic stockings
- Where
- Italy
- Sponsor
- University of Padova
Trauma, Surgery
Lovenox 30 mg Twice Daily (BID) Versus 40 mg Once Daily (QD)
The risk of developing a blood clot occurs in up to 60% of all critical care patients. Many times enoxaparin (or Lovenox) is given to patients who are at a higher risk of developing clots in their legs or lungs.
- Conditions
- Trauma, Surgery, Deep Vein Thrombosis (DVT), Thromboembolic Events
- Trial name
- NCT02342444
- Testing
- Enoxaparin Sodium Injection 30 mg BID, Enoxaparin Sodium Injection 40 mg QD
- Where
- United States
- Volunteers
- 606 people
- Sponsor
- Oregon Health and Science University
Venous Thromboembolism
CoMbination of Data From European Cohorts as Part of the European MORPHEUS Project [HORIZON-HLTH-2022-11-01] - "MC-MORPHEUS".
Combine clinical, biological and morphological data from 14 French and European cohorts into a single database.
- Trial name
- MC-MORPHEUS (NCT07328152)
- Where
- France
- Volunteers
- 20,000 people
- Sponsor
- University Hospital, Brest
Venous Thromboembolism
Thrombosis Outcomes in Pediatric Venous Thromboembolism
'The TOP Study' is a prospective cohort study whose main objective is to develop better prognostic biomarkers and identify children at risk of adverse thrombotic outcomes very early in the course after an initial venous…
- Trial name
- TOP (NCT03068923)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Texas Southwestern Medical Center
Deep Vein Thrombosis, Pulmonary Embolism
Japanese Registry of Rivaroxaban Effectiveness & Safety for the Prevention of Recurrence in Patients With Deep Vein Thrombosis and Pulmonary Embolism
To clarify the effectiveness and safety of the direct factor Xa inhibitor rivaroxaban in domestic clinical use for patients with deep vein thrombosis and pulmonary embolism
- Trial name
- NCT03091621
- Where
- Japan
- Volunteers
- 1,000 people
- Sponsor
- Nihon University
Bladder Cancer Patients Candidate for Radical Cystectomy
Preoperative Subclinical DVT Screening in Locally Advanced Bladder Cancer Patients Candidate for Radical Cystectomy.
Preoperative subclinical DVT screening in locally advanced bladder cancer patients candidate for radical cystectomy.
- Trial name
- NCT04502498
- Testing
- Lower limb duplex & doppler
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Suspected Pulmonary Embolism, Deep Venous Thrombosis
Canadian Pulmonary Embolism Diagnosis Study (CANPEDS)
The main objective of the trial is to determine whether D-dimer testing combined with assessment of Pre-Test-Probability (using a standardized clinical model) can be used to markedly simplify the diagnostic process for PE.
- Trial name
- NCT00182546
- Testing
- Two diagnostic management strategies
- Where
- 7 sites in Canada
- Volunteers
- 1,126 people
- Sponsor
- Hamilton Health Sciences Corporation
Covid19, Myocardial Infarction
Outcomes of Patients Who Survived Treatment on an Intensive Care Unit for COVID-19 in England and Wales
This retrospective cohort study aims to characterise outcomes for patients treated on an intensive care unit (ICU) with COVID-19 in England and Wales, one year after discharge from hospital.
- Conditions
- Covid19, Myocardial Infarction, Stroke, Critical Illness
- Trial name
- OPTIC-19 (NCT04838106)
- Testing
- Not applicable as observational study
- Where
- United Kingdom
- Volunteers
- 319,600 people
- Sponsor
- University of Oxford