Clinical trials: Damage Control
Vegetative State, Minimally Conscious State
Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness
Previous studies showed that anodal transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal (DLPF) cortex transiently improves performance of memory and attention.
- Conditions
- Vegetative State, Minimally Conscious State, Disorders of Consciousness
- Trial name
- tDCS in DOC (NCT01673126)
- Testing
- Anodal tDCS
- Where
- Belgium
- Volunteers
- 55 people
- Sponsor
- University of Liege
Spastic Diplegic Cerebral Palsy
Effects of Core Stabilization Exercises on Postural Control in Spastic Diplegic CP Children
This randomized controlled trial will evaluate the effectiveness of a 12-week comprehensive core stabilization exercise program on balance, trunk control, and gross motor function in children with spastic diplegic cerebral palsy.
- Trial name
- NCT07736417
- Testing
- Exercise, Conventional
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Shifa Tameer-e-Millat University
Radiation Enteritis, Radiation Proctitis
Study to Prevent Radiation Induced Damage to Bowel Using a Prebiotic Enhanced Diet.
The study will consist of pair of double-blind placebo-controlled trials of dietary supplementation with 15g/day FructoOligoSaccharide (FOS) for 7.5 weeks in patients with prostate carcinoma or 5 weeks in patients with cervical…
- Trial name
- NCT01414517
- Testing
- FructoOligoSaccharide, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 220 people
- Sponsor
- University College London Hospitals
Cold-water Immersion, Protein-carbohydrates Supplementation
Effects on CK, RPE, VAS Scale and Physical Performance of Three Recovery Methods in Elite Basketball Players
The aim of this study was to compare the effects of cold water intermittent ion (CWI), carbohydrate and protein supplementation (SUPPL), and active recovery (ACT) on creatine kinase (CK), perceptual and performance markers of…
- Conditions
- Cold-water Immersion, Protein-carbohydrates Supplementation, Active Recovery, Placebo
- Trial name
- NCT05805540
- Testing
- Cold-water immersion, Protein-carbohydrates supplementation, Active recovery
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
The Precision Personal Timeline in Definitive Surgery Associated With Outcome
Timing of Damage Control Orthopedic Surgery
The decision to operate and surgical timing on multi-trauma patients remains controversial, inappropriate surgical timing may cause more complications which lead to poor prognosis.
- Trial name
- NCT05785143
- Testing
- Utilizing dry lab database to analyze the prognostic factors of multi-trauma patients and determine the optimal timing of definitive orthopedic operation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- China Medical University Hospital
Cerebral Palsy Children
Effects of Hydrotherapy in Children With Cerebral Palsy
The goal of this observational study is to learn the effects of hydrotherapy in children with cerebral palsy. It aims to answer if hydrotherapy is affective on balance and selective motor control of the children with cerebral…
- Trial name
- NCT06899035
- Testing
- Intervention Group (water-based and conventional exercise), control group (conventional exercise)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Febrile Seizures, Oxidative Stress
8-OHdG and Oxidative Stress in Febrile Seizures
This prospective case-control study investigates whether serum 8-hydroxy-2'-deoxyguanosine (8-OHdG), an established biomarker of reactive oxygen species-mediated DNA oxidation, is elevated in children with febrile seizures…
- Conditions
- Febrile Seizures, Oxidative Stress, Oxidative DNA Damage
- Trial name
- NCT07660003
- Testing
- Group 1 Health Controls, Group 2 SFC, Group 3 CFC
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Kayseri City Hospital
Spastic Cerebral Palsy
Effect of Elastic Lower Extremity Orthosis on Gait and Balance in Children With Spastic Cerebral Palsy
This randomized controlled trial aims to evaluate the effect of an elastic lower extremity orthosis on gait and balance in children with spastic cerebral palsy who present with an in-toeing gait pattern.
- Trial name
- NCT07122362
- Testing
- Elastic Lower Extremity Orthosis, Neurodevelopmental Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Gazi University
Cerebral Palsy (CP), Hemiplegic Cerebral Palsy
Bootle Blast: Pilot Randomized Controlled Trial
One in 500 Canadians has cerebral palsy (CP), a lifelong condition affecting movement and function. Physical and occupational therapies greatly benefit children with CP but can be costly and difficult to access.
- Trial name
- NCT07289360
- Testing
- Bootle Blast Intervention, Standard Care (Comparator)
- Where
- 3 sites in Canada
- Volunteers
- 46 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cerebral Palsy, Collaborative Intervention Process
Effectiveness of Family-Professional Collaboration on Functional Goals Achievement of Children With Cerebral Palsy and Caregivers' Quality of Life and Burden
The aim of this study is to examine the effect of implanting the family-professional collaboration practice model on the functional goals achievement of children with CP and their caregivers' quality of life and burden.
- Conditions
- Cerebral Palsy, Collaborative Intervention Process, Functional Goals Achievement
- Trial name
- NCT05709080
- Testing
- family-professional collaboration practice model
- Where
- Saudi Arabia
- Volunteers
- 54 people
- Sponsor
- King Saud University
Cerebral Palsy
A Study Protocol for an Online Intervention to Promote School Engagement
Cerebral Palsy (CP) is a neurological, non-progressive, and permanent developmental disorder that mainly affects movement and posture, with a prevalence of 3 to 4 children per 1000 live births.
- Trial name
- NCT04247516
- Testing
- Online-intervention group I (IGI), Online-intervention group II (IGII)
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- University of Minho
Cerebral Palsy, Hemiplegic Cerebral Palsy
Effects of Botulinum Toxin Injection on Sensation and Postural Control in Children With Hemiplegic Cerebral Palsy
In this study, the investigators aimed to investigate the effects of botulinum neurotoxin type A (BoNT-A) injection applied to the ankle plantar flexor muscles on lower extremity sensation and quantitative balance parameters in…
- Trial name
- NCT04940143
- Testing
- Botulinum toxin type-A (Onabotulinum toxin type-A), Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Marmara University
Cerebral Palsy
Effects of Horse Riding Simulator With or Without Visual Feedback on Balance and Postural Control
Spastic cerebral palsy is a neurological condition that causes muscle spasticity and motor impairments, greatly impacting a child's ability to maintain balance and control their posture.
- Trial name
- NCT06231147
- Testing
- HORSE RIDING SIMULATOR WITH VISUAL FEEDBACK, HORSE RIDING SIMULATOR WITHOUT VISUAL FEEDBACK
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Cerebral Palsy, Down's Syndrome
DIR/ Floortime™ Parent Training Intervention for the Children With Developmental Disabilities
The objective of this study is to test whether adding the parent training program using the relationship-based approach could help the children with development disabilities (DDs) would confer additional benefits over routine…
- Conditions
- Cerebral Palsy, Down's Syndrome, Delayed Development
- Trial name
- RCT/DD (NCT01794013)
- Testing
- Parent training, Routine care
- Where
- Thailand
- Volunteers
- 48 people
- Sponsor
- Kingkaew Pajareya
Cerebral Palsy
Neuromotor Control During Walking in Children With Cerebral Palsy
One out of every three children with cerebral palsy (CP) falls daily, with more than half of the falls occurring while walking. To avoid falling, the nervous system must continuously monitor how the body moves and, when an…
- Trial name
- NCT05233748
- Testing
- Stochastic Resonance (SR)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Infants at Risk of Cerebral Palsy
A Randomized Controlled Trial of Hybrid Environmental Enrichment-Based Early Intervention in Infants at Risk of Cerebral Palsy
This randomized controlled trial aims to evaluate the effects of a hybrid environmental enrichment-based early intervention grounded in the Homeostasis-Enrichment-Plasticity (HEP®) Approach in infants at risk of cerebral palsy…
- Trial name
- NCT07116148
- Testing
- HEP-Based Early Intervention, Conventional Early Intervention
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Medipol University
Sialorrhea, Spastic Cerebral Palsy (sCP)
Effect of SCS Technique on Oromotor Skills in Children With CP
This study evaluates the clinical efficacy of the Strain Counter-Strain (SCS) technique on improving oromotor functions in children with spastic cerebral palsy.
- Conditions
- Sialorrhea, Spastic Cerebral Palsy (sCP), Strain Counterstrain Technique, Oral Motor Functions
- Trial name
- NCT07516860
- Testing
- Strain Counter-Strain (SCS), Designed Oral Motor Program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
CP (Cerebral Palsy)
Tolerance of a Motorized Orthosis Reproducing Walking Movement vs Conventional Standing-up Devices in Child With CP
Cerebral palsy (CP) includes all the sensorimotor development disorders leading to balance, gait and movement disruptions. These disorders are related to lesions of the central nervous system (CNS) that occurs at birth or during…
- Trial name
- EOMEC/CP (NCT02669160)
- Testing
- PC Innowalk, Conventional passive stander
- Where
- 4 sites in France
- Volunteers
- 25 people
- Sponsor
- Lille Catholic University
Neuromuscular Diseases in Children, Cerebral Palsy, Spastic
Muscle Spasticity Reduction in Children With Cerebral Palsy by Means of Hippotherapy
The aim of this study is to evaluate if a intervention with hippotherapy will improve spasticity for children ages 3-14 who have cerebral palsy.
- Conditions
- Neuromuscular Diseases in Children, Cerebral Palsy, Spastic, Spasticity, Muscle
- Trial name
- NCT03212846
- Testing
- Hippotherapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Cadiz
Cerebral Palsy
The Efficacy of Targeted Training on the Postural Control and Gross Motor Function in Children With Cerebral Palsy
The project aims to test the effectiveness and explore the possibility of performing a novel therapeutic approach, targeting to increase strength and coordination around the trunk, giving a more active and functional seating and…
- Trial name
- NCT01357954
- Testing
- Regular physiotherapy, Targeted Training
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- Hvidovre University Hospital