Clinical trials: Database
Root Canal Treatment
Retrospective Database Study: Influence of Post-endodontic Restoration Placement on Survival of Root Canal-treated Teeth
The aim of this study is to assess the influence (i.e. type and timing) of post-endodontic restorations on the survival of root canal-treated teeth and to determine the influence of patient-, tooth-, treatment-, and…
- Trial name
- NCT06441058
- Testing
- No patient treatment is associated with the study
- Where
- Germany
- Volunteers
- 541 people
- Sponsor
- University of Göttingen
Pancreatic Cancer
Multicentric Database for KRAS Mutant Pancreatic Cancer
Construction and Maintenance of a Precision Subtyping-Based Clinical Cohort for Targeted Therapy in KRAS-Mutant Pancreatic Cancer
- Trial name
- NCT07557849
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Fudan University
Pregnancy Related, Atopic Dermatitis
An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis Exposed to Ruxolitinib Cream Versus Topical Corticosteroids During Pregnancy: A US Claims Database Analysis
This study is to assess infant outcomes of women with AD who were exposed to ruxolitinib cream during pregnancy compared with a control cohort of women with AD who were exposed to a topical corticosteroid (TCS) during pregnancy.
- Trial name
- NCT06627335
- Testing
- Ruxolitinib Cream, TCS
- Where
- United States
- Volunteers
- 5,621 people
- Sponsor
- Incyte Corporation
Pregnant Women, Children
JiAngSu Maternal and INfant HEalth Database
With the implementation of China's universal two-child policy and a notable rise in adverse pregnancy outcomes, leveraging electronic health records (EHR) has become crucial for enhancing maternal health.
- Trial name
- JASMINE (NCT06641479)
- Where
- China
- Volunteers
- 1,570,360 people
- Sponsor
- Yang Zhao
Still Disease
Auvergne-Rhône-Alpes-Limousin Research Database for Still's Diseases in Children and Adults
Adult-Onset Still's disease is a polygenic autoinflammatory disease of unknown etiology. The autoinflammatory character individualizes it from autoimmune autoantibody diseases.
- Trial name
- AURAL-STILL (NCT05055882)
- Testing
- children and adult with Still's disease in Auvergne-Rhône-Alpes-Limousin hospital
- Where
- 16 sites in France
- Volunteers
- 400 people
- Sponsor
- Hospices Civils de Lyon
Cancer, Immune-related Adverse Event
EXploring Immune-related Adverse Events of Immune checkpoinT Inhibitors Using VigiBase, the WHO Pharmacovigilance Database
This is an observational, retrospective pharmacovigilance study based on reports registered and transmitted in VigiBase®, the WHO's international database.
- Conditions
- Cancer, Immune-related Adverse Event, Immune Checkpoint Inhibitor-Related Myocarditis
- Trial name
- EXIT (NCT05934214)
- Testing
- Immune checkpoint inhibitor
- Where
- 2 sites in France
- Volunteers
- 141,630 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
to Contribute to a Better Control of COVID-19 in Children in Niger
COVID-19 IN CHILDREN IN NIGER, 2020
On January 30, 2020, the WHO declared COVID-19 a global health emergency. Children were affected with less severe forms. Niger had implemented measures in a context where children are a source of contamination.
- Trial name
- NCT05886179
- Testing
- cross-sectional study
- Where
- Niger
- Volunteers
- 572 people
- Sponsor
- Centre de Recherche Médicale et Sanitaire
The Precision Personal Timeline in Definitive Surgery Associated With Outcome
Timing of Damage Control Orthopedic Surgery
The decision to operate and surgical timing on multi-trauma patients remains controversial, inappropriate surgical timing may cause more complications which lead to poor prognosis.
- Trial name
- NCT05785143
- Testing
- Utilizing dry lab database to analyze the prognostic factors of multi-trauma patients and determine the optimal timing of definitive orthopedic operation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- China Medical University Hospital
Heart Diseases
Database of Tissue Samples to Understand the Inflammatory Response After Cardiac Surgery
The aim of this study is to collect non-individual related blood samples for the compelling of a unique database of tissue samples to understand the inflammatory responds after cardiac surgery on an on-going basis.
- Trial name
- NCT02488876
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- RWTH Aachen University
Neoplasm Metastasis
Bone Metastases Database of Patients Treated Surgically for Impending or Pathologic Fracture of Long Bones
The aims of this study are to collect prospective data on the natural history of bone metastases (BMs) and skeleta related events (SREs),
- Trial name
- BMD (NCT03416959)
- Testing
- intramedullary fixation or endoprosthetic reconstruction
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Istituto Ortopedico Rizzoli
Cancer
Myelodysplastic Syndrome and Acute Myeloid Leukemia Related to PARP Inhibitors (MyeloRIB)
Although PARP inhibitors (PARPi) have proved effective in treating many cancers, few patients receiving PARPi may experience rare but life-threatening adverse events such as myelodysplastic syndrome (MDS) and/or acute myeloid…
- Trial name
- NCT04326023
- Testing
- PARP Inhibitors
- Where
- France
- Volunteers
- 178 people
- Sponsor
- University Hospital, Caen
Vaccine Adverse Reaction
COVID-19 Vaccines Associated Malaise
COVID-19 vaccines induced malaise have recently been reported in the literature. Our study aims to identify risk factors associated with the onset of COVID-19 vaccines induced malaise and to assess if certain COVID-19 vaccines…
- Trial name
- NCT05234333
- Testing
- SARS-CoV-2 vaccine
- Where
- France
- Volunteers
- 1,534,706 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Eosinophilic Esophagitis
Prospective Database for Eosinophilic Esophagitis (EoE) of Pediatric Population
Eosinophilic Esophagitis (EoE) is a chronic, immune-mediated allergic inflammatory disorder that is being diagnosed with increased frequency.
- Trial name
- EoE (NCT05176249)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Child Abuse
Proposal of a Method Using the PMSI and SNIIRAM National Databases to Estimate the Frequency of Physical Abuse and to Identify th Eassociated At-risk Situations and Consequences in Children Aged 0 to 5 Years in France
The epidemiological data currently available on child abuse in France are very inadequate. They do not make it possible to know the number of child victims, nor the precise context and impact of this violence.
- Trial name
- MENFIS (NCT04371484)
- Testing
- ICD-10
- Where
- France
- Volunteers
- 4,002,359 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Leukemia, Myeloblastic, Acute
Prospective Database for Acute Myeloblastic Leukemia
Prospective Database for Acute Myeloblastic Leukemia
- Trial name
- NCT00538278
- Testing
- Database
- Volunteers
- 2,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Endocrine Disease
Comprehensive Data Collection and Follow-Up for Patients With Thyroid, Parathyroid and Adrenal Disease
The goal of this data review study is to collect data to learn more about thyroid, parathyroid, and adrenal disease.
- Trial name
- NCT03050762
- Testing
- Data Collection, Follow Up
- Where
- United States
- Volunteers
- 15,000 people
- Sponsor
- M.D. Anderson Cancer Center
Airway Management, Intubation, Intratracheal
The Difficult Airway Management Trial: "The DIFFICAIR-Trial"
In general anesthetic the patient is deprived of his awareness and ability to breathe. It is therefore one of the most important tasks in anesthesia to ensure the patient's airway and breathing.
- Trial name
- DIFFICAIR (NCT01718561)
- Testing
- SARI
- Where
- 28 sites in Denmark
- Volunteers
- 76,058 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Schizophrenia
Establishing a Clinical Database and Biobank for Schizophrenia：A Cohort Study
This is a multicenter study conducted in collaboration with Central South University, The First Affiliated Hospital of Zhengzhou University, Nanjing Brain Hospital of Nanjing Medical University, and Anhui Mental Health Center.
- Trial name
- NCT06123897
- Testing
- Regular follow-up assessments without intervention., Cross-sectional assessment
- Where
- 4 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Central South University
Breast Neoplasms
A Study to Understand About the Study Medicine Palbociclib in Breast Cancer Patients After it is Out in the Japanese Market
The purpose of the study is to: compare the chances of getting interstitial lung disease (ILD) in new users of palbociclib plus fulvestrant to new users of fulvestrant alone (using data from before palbociclib was out in the…
- Trial name
- NCT07096024
- Testing
- palbociclib plus fulvestrant, fulvestrant
- Where
- United States
- Volunteers
- 95,637 people
- Sponsor
- Pfizer
Bronchial Asthma
A Pharmaceopidemiological Study in Patients Who Use Symbicort SMART
To investigate how common it is that patients using Symibort SMART take high average daily doses that are not considered appropriate by their physician (overuse) or are hospitalised due to their asthma at least partly due to…
- Trial name
- NCT00503061
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca