Clinical trials: Deficiency Vitamins
X-Linked Hypophosphatemia
Study of Longitudinal Observation for Patient With X-linked Hypophosphatemic Rickets/Osteomalacia in Collaboration With Asian Partners
Through observation of patients with X-linked hypophosphatemic rickets/osteomalacia (XLH) for up to 10 years, the study intends to collect data that allow achievement of the following objectives: 1.
- Trial name
- SUNFLOWER (NCT03745521)
- Testing
- no intervention
- Where
- Japan
- Volunteers
- 226 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Vitamin D Deficiency
Prevention of Vitamin D Deficiency
Breastfed infants living in a northern location (41 degrees N) are at high risk of vitamin D deficiency during winter. This trial is designed to determine how much supplemental vitamin D breastfed infants need to receive in order…
- Trial name
- NCT00494104
- Testing
- Vitamin D drops, 200 or 400 or 600 IU/day or 800 IU/day
- Where
- United States
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV Infections, Pregnancy Complications
Trial of Vitamins Among Children of HIV-infected Women
The purpose of this study is to examine the effects of multivitamin (B, C, E) supplementation on reducing the risk of morbidity and mortality outcomes among children born to HIV positive mothers, compared to placebo…
- Trial name
- NCT00197730
- Testing
- Multivitamins - vitamins B complex, C and E
- Where
- Tanzania
- Volunteers
- 2,387 people
- Sponsor
- Harvard School of Public Health (HSPH)
Hypophosphatemic Rickets, X-Linked Dominant
Effect of Cinacalcet on Parathyroid Hormone Secretion in Children and Adolescents With Hypophosphatemic Rickets
This study will measure the effect of cinacalcet (Sensipar) on parathyroid hormone (PTH) secretion in children and adolescents with hypophosphatemic rickets (XLH).
- Trial name
- NCT00195936
- Testing
- Cinacalcet
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Children's Mercy Hospital Kansas City
Vitamin D Deficiency
Treatment of Vitamin D Insufficiency
The purpose of this study is to answer the following questions: Does vitamin D increase calcium absorption, bone mass and muscle mass and function in women past menopause who have mildly low vitamin D levels? Do these benefits…
- Trial name
- NCT00933244
- Testing
- High Dose Vitamin D3, Low Dose Vitamin D3
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Vitamin D Deficiency
The Effect of Vitamin D on Bone Accretion and Turn-Over in Young Girls
Objectives To evaluate the effect of increased vitamin D intake on vitamin D status, bone mass and bone turnover in young girls aged 12-13.
- Trial name
- NCT00267540
- Testing
- cholecalciferol (D3) (vitamin)
- Where
- Denmark
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Choline Deficiency, Liver Injury
Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support
TARA-001-301 is a Phase 2b/3 randomized Open-Label Dose-Selection study with an Open-Label Extension and randomized Double-Blind, Placebo-Controlled Study with Open-Label Extension to investigate the safety and efficacy of…
- Trial name
- THRIVE-3 (NCT06910943)
- Testing
- Choline Chloride for Injection
- Where
- 18 sites in United States, Belgium and 4 more
- Volunteers
- 129 people
- Sponsor
- Protara Therapeutics
Asthma, Vitamin D Deficiency
Vitamin D Deficiency and Asthma Exacerbation
The study aim is in two phases. First phase: to evaluate the influence of vitamin D deficiency on asthma severity, degree of airway obstruction and frequency of asthma exacerbations.
- Conditions
- Asthma, Vitamin D Deficiency, Disease Exacerbation
- Trial name
- AVD (NCT02661191)
- Testing
- oral cholecalciferol
- Volunteers
- 119 people
- Sponsor
- University of Turin, Italy
Nutritional Rickets, Bone Turnover Rate Disorder
Effectiveness of Vitamin C Supplementation in Treatment of Rickets
Effectiveness of therapeutic dose of vitamin C in infants and children with nutritional rickets as an adjuvant therapy with vitamin D and calcium The study is two armed Randomized Control Trial, to validate the role of Vit C…
- Trial name
- NCT05310760
- Testing
- Vit C
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Postmenopausal Osteoporosis, Postmenopause
Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its Treatment
Recently, an increase in the prevalence of hyperparathyroidism and hypovitaminosis D in postmenopause women has been occurring in Mexico and the world.
- Conditions
- Postmenopausal Osteoporosis, Postmenopause, Hyperparathyroidism, Secondary, Hypovitaminosis D
- Trial name
- NCT05347082
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 47 people
- Sponsor
- Hospital Regional 1o de Octubre
Vitamin D Deficiency
Vitamin D3 Supplementation Pilot Study
The purpose of this research study is to determine whether taking vitamin D, every day, over a 12 week period will improve the vitamin D status, risks for poor heart health, risks for developing type 2 diabetes, and/or muscle…
- Trial name
- NCT01546103
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Vitamin D Deficiency
Efficacy of Daily Vitamin D3 Supplementation in Normal Weight Adolescents
The study is designed to evaluate the increment of serum 25 (OH) vitamin D levels in normal weight adolescents following a 12-week supplementation with Vitamin D3 2000 IU/day.
- Trial name
- NCT01058720
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Anemia, Iron-Deficiency, Deficiency, Vitamin A
Newly Formulated, Extruded Fortified-blended Foods for Food Aid: the MFFAPP Tanzania Efficacy Study
Corn-soy vitamin and mineral fortified blended foods (FBFs) are primarily used for food aid, although sorghum and cowpea may be suitable alternative FBF commodities.
- Trial name
- NCT02847962
- Testing
- Corn Soy Blend Plus (CSB+), Corn Soy Blend 14 (CSB14), White Sorghum Cowpea Blend Variety 1
- Volunteers
- 2,179 people
- Sponsor
- Kansas State University
Acute Lymphoblastic Leukemia, Vitamin d Deficiency
Effect of Supplementation With ω-3 Fatty Acids, Vitamin D and Calcium in Patients With Acute Lymphoblastic Leukemia.
The purpose of this study is to evaluate the efficacy of supplementation with Omega 3, Vitamin D and Calcium, in a cohort of children with ALL undergoing treatment and compare changes in the concentrations of biomarkers of bone…
- Trial name
- NCT05950204
- Testing
- ω-3 polyunsaturated fatty acids (DHA and EPA), Vitamin D (cholecalciferol), Calcium (calcium carbonate)
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Cardiovascular Diseases, Heart Diseases
Plasma Homocysteine Distribution in the United States
To describe the distribution of homocysteine and prevalence of hyperhomocysteinemia with emphasis on race, sex and age. To determine the extent to which hyperhomocysteinemia is associated with status of folate and vitamin B12.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hyperhomocysteinemia
- Trial name
- NCT00005483
- Sponsor
- Tufts University
Early Childhood Caries, Vitamin D Deficiency
Vitamin D Status With Early Childhood Caries
Studies that give people vitamin D supplements to prevent caries have found that vitamin D is effective at preventing the development of caries.
- Trial name
- NCT03521492
- Testing
- serum vitamin D , calcium , parathyroid hormone and albumin level
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Saudi Arabia
X-linked Hypophosphatemia (XLH)
Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age
A Phase 1/2, Open-label, Multicenter, Non-randomized Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Paediatric Patients from Birth to Less than 1 Year of Age with X-linked Hypophosphatemia…
- Trial name
- NCT04188964
- Testing
- Burosumab
- Where
- 9 sites in Austria, France and 4 more
- Volunteers
- 16 people
- Sponsor
- Kyowa Kirin Pharmaceutical Development Ltd
Vitamin D Deficiency
Utility of a Urine Screening Tool for Vitamin D Deficiency in Infants and Toddlers
Background: Vitamin D plays a key role in calcium absorption in the gut and in skeletal development. Vitamin D deficiency is common, affecting an estimated one billion people worldwide, including developed countries.
- Trial name
- NCT01105689
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Down Syndrome, Vitamin D Deficiency
Effect of Exercise Intensity on Vitamin D
Children with Down's syndrome (DS) are more liable to vitamin D deficiency. Treating this deficiency with supplements is associated with the risk of intoxication due to increased intestinal absorption or decreased vitamin D…
- Trial name
- NCT05024110
- Testing
- High intensity treamill exercise training., Moderate intensity treamill exercise training.
- Where
- Saudi Arabia
- Volunteers
- 44 people
- Sponsor
- Taif University
Vitamin D Deficiency, Stem Cell Transplant Complications
A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT
Research has suggested that children with sufficient vitamin D levels undergoing hematopoietic stem cell transplant (HSCT) have improved outcomes, including lower incidences of infection and graft-versus-host disease (GVHD), as…
- Conditions
- Vitamin D Deficiency, Stem Cell Transplant Complications, Pediatric Cancer, Blood Disorder
- Trial name
- NCT03176849
- Testing
- Vitamin D3, Standard Vitamin D3 Supplementation
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Phoenix Children's Hospital