Clinical trials: Degenerative Arthritis
Osteoarthritis, Hip, Arthritis
A Clinical Investigation of the M2a-Magnum™ Hip System
The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of the M2a-Magnum™ Hip System
- Conditions
- Osteoarthritis, Hip, Arthritis, Rheumatoid Arthritis, Joint Disease
- Trial name
- NCT00698347
- Testing
- M2a-Magnum™ Hip System
- Volunteers
- 249 people
- Sponsor
- Biomet Orthopedics, LLC
Hip Arthrosis, Hip Injuries
Retrospective Assessment of the Morphology of Acetabular Defects: A 3D Reconstruction Approach
In this study, we aim to develop a statistical shape model and use it to reconstruct the shape of acetabula with severe defects (Paprosky 3a-3b). This will allow us to visualise and assess the morphology of the missing bone.
- Trial name
- NCT04638140
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Patellofemoral Osteoarthritis, Arthroplasty Complications
Failure Analysis of Patellofemoral Arthroplasty
The purpose of the retrospective cohort study is 1) to determine preoperative risk factors for revision af patellofemoral arthroplasty, and 2) to provide a detailed description of indications for revision after patellofemoral…
- Conditions
- Patellofemoral Osteoarthritis, Arthroplasty Complications, Knee Osteoarthritis
- Trial name
- NCT04772625
- Testing
- Patellofemoral arthroplasty
- Where
- Denmark
- Volunteers
- 550 people
- Sponsor
- Anders Odgaard
Osteoarthritis Knee
Effectivity of Allogenic Umbilical Cord Mesenchymal Stem Cells Conditioned Media for Osteoarthritis of the Knee Joint
Osteoarthritis (OA) is a joint disorder that often occurs and causes disability. This disorder is characterized by an inflammatory reaction in the synovial joints accompanied by a gradual degeneration process in the articular…
- Trial name
- NCT06688318
- Testing
- Intra-articular secretome injection therapy
- Where
- Indonesia
- Volunteers
- 11 people
- Sponsor
- Kementerian Riset dan Teknologi / Badan Riset dan Inovasi Nasional, Indonesia
Rheumatoid Arthritis
Transplantation of Bone Marrow Derived Mesenchymal Stem Cells in Affected Knee Osteoarthritis by Rheumatoid Arthritis
Osteoarthritis of the knee is one of the most common causes of disability among elderly. Arthritis rheumatoid is an autoimmune disease which causes multi articular arthritis, such as knee osteoarthritis.
- Trial name
- NCT01873625
- Testing
- mesenchymal cell transplantation
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Royan Institute
Knee Arthroplasty, Knee Arthroplasty, Total
Progression of Health Related Quality of Life of Patients Waiting for Total Knee Arthroplasty
To evaluate the progression on patients suffering from end stage OA whilst being on the waiting list for TKR
- Conditions
- Knee Arthroplasty, Knee Arthroplasty, Total, Knee Replacement, Total, Replacement, Total Knee
- Trial name
- TKA HRQoL (NCT03492320)
- Testing
- Health Quality of Life Questionnaire Assessment
- Volunteers
- 127 people
- Sponsor
- Dr. Ho Ki Wai
Osteoarthritis, Traumatic Arthritis
The Post-marketing Surveillance to Evaluate the Efficacy of CHONDRON (Autologous Cultured Chondrocyte) by Arthroscopy
A clinical trial to evaluate the long-term efficacy and safety of Chondron (Autologous cultured Chondrocyte) administered through arthroscopy from the drug's 48 weeks efficacy and safety evaluation with 96 weeks follow-up in…
- Trial name
- NCT02539069
- Testing
- Chondron Implantation
- Where
- South Korea
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Arthropathy, Hip Arthropathy
Restoration Anatomic Acetabular Shell Revision Study
This study will be a non-randomized, ambidirectional (retrospective and prospective) study where all subjects will be followed prospectively.
- Conditions
- Arthropathy, Hip Arthropathy, Hip Osteoarthritis
- Trial name
- RAS (NCT05591859)
- Testing
- Restoration Anatomic Acetabular Shell
- Where
- United States
- Sponsor
- Stryker Orthopaedics
Knee Injury, Knee Osteoarthritis
Monitoring Of Helsingborg Acute Knee Injuries (MOHAK)
Using magnetic resonance imaging (MRI), laboratory analyses and patient reported outcomes, the overall aim of this study is to investigate structural injuries and biochemical alterations in the acutely injured knee and to relate…
- Trial name
- NCT01382173
- Where
- Sweden
- Volunteers
- 192 people
- Sponsor
- Lund University
Osteoarthritis, Arthralgia
Leeches for the Treatment of Knee Osteoarthritis
Previous studies have not addressed the question, whether or not a repeated leeching can supply symptomatic relief of osteoarthritic pain for extended periods of time.
- Trial name
- NCT00435773
- Testing
- Single Leeching, Repeated Leeching after 4 weeks
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- RWTH Aachen University
Knee Osteoarthritis
The Effect of a Group Exercise Intervention on Balance in People With Knee Osteoarthritis: a Pilot Study
In this study, the investigators want to find out if a 12-week exercise program improves balance in people with knee osteoarthritis.
- Trial name
- NCT06807541
- Testing
- Exercise intervention
- Where
- 2 sites in Canada
- Volunteers
- 32 people
- Sponsor
- University of the Fraser Valley
Osteoarthritis, Knee, Joint Disease
Matched Pair Study - Kinematic Vs Mechanical Alignment
The aim of this study is to evaluate postoperative knee function after total knee arthroplasty performed according to the anatomical alignment and compare these results to those of a matched historical cohort of patients operated…
- Trial name
- NCT03446391
- Testing
- Kinematic alignment, Mechanical alignment, GMK Sphere®
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Medacta International SA
Osteoarthritis, Varus Malalignment
Ellipse Intramedullary High Tibial Osteotomy Nail Study
The purpose of this study is to collect outcomes data in patients implanted with the Ellipse IM HTO Nail System.
- Trial name
- NCT02519218
- Testing
- Ellipse Technologies Intramedullary High Tibial Osteotomy Nail System
- Volunteers
- 6 people
- Sponsor
- Ellipse Technologies, Inc.
Knee Osteoarthritis
Safety of Electrotherapy in Patients With Knee Osteoarthritis and Cardiac Diseases
This study aimed to asses whether physyical therapy (e.g. electrotherapy in the form of low, medium or high frequency currents, massage and kinetotherapy) for treatment of knee osteoarthritis can induce or aggravate certain…
- Trial name
- NCT04148079
- Testing
- physical therapy
- Volunteers
- 46 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Osteoarthritis, Knee
Is Phonophoresis Treatment Effective?
The specimens from patients as knee osteoarthritis diagnosed who was applied ibuprofen phonophoresis will be analyzed.
- Trial name
- NCT02358707
- Testing
- Ibuprofen phonophoresis
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Cukurova University
Cartilage Damage, Osteochondral Lesion
Investigation of the Effectiveness of Physiotherapy and Rehabilitation After Osteochondral Allograft Transplantation Operation
The aim of our study is to add to the literature the effect of the effectiveness of the physiotherapy and rehabilitation in the clinic, which will be applied to the patients after the osteochondral allograft transplantation…
- Conditions
- Cartilage Damage, Osteochondral Lesion, Allograft, Osteoarthritis of Knee
- Trial name
- NCT06644092
- Testing
- Investigation of the Effectiveness of Physiotherapy and Rehabilitation After Osteochondral Allograft Transplantation Operation
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Yeditepe University
Knee Osteoarthritis
Validation of a New Technique for the Evaluation of the Patello-femoral Joint Kinematics
The objective of this study is to validate a new technique for intraoperative quantification of the patello-femoral joint kinematics in patients undergoing total knee replacement, and for postoperative quantification of implanted…
- Trial name
- CINE-FEMORO (NCT03448198)
- Testing
- Total knee replacement
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Primary Osteoarthritis of Knee Nos
Rate of Infection After Using Antibiotic Loaded Cement and Regular Cement in Total Knee Arthroplasty
Our study will be a prospective study To compare between the rate of infection after using antibiotic loaded cement and regular cement after total knee arthroplasty in primary knee osteoarthritis.this will be at assiut university…
- Trial name
- NCT06117839
- Testing
- using antibiotic loaded cement and regular cement after total knee arthroplasty in primary knee osteoarthritis.
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assiut University
Rupture of Anterior Cruciate Ligament, Osteoarthritis
Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): Onsite Follow-up
In this study we will examine patients who have undergone unilateral ACL reconstruction surgery to determine which structural and functional characteristics of the knee two and ten years post reconstruction surgery, aspects of…
- Trial name
- MOON-Onsite (NCT00478894)
- Where
- 4 sites in United States
- Volunteers
- 432 people
- Sponsor
- Vanderbilt University
Hip Osteoarthritis
Opioid-free Total Hip Arthroplasty
The primary objective of investigators' proposed study is to demonstrate that the following two cohorts undergoing total hip arthroplasty will have equivalent visual analog scale (VAS) scores up to 3 months post-operatively: one…
- Trial name
- NCT04421196
- Testing
- Exclusion of opioid analgesics
- Sponsor
- Johns Hopkins University