Clinical trials: Delayed Cord Clamping
Placental Transfusion, Hematocrit Anemia
Delayed Cord Clamping in Infants Born by 'Two-step' Vaginal Delivery
The investigators conducted a RCT (parallel group study with 1:1 randomisation) comparing ECC (at 60 seconds) and DCC (at 180 seconds) in 90 cases of normal birth by' two-step' delivery.
- Trial name
- NCT04351997
- Testing
- Cord clamping
- Where
- 3 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Policlinico Abano Terme
Premature Infant, Umbilical Cord
Umbilical Cord Milking vs Delayed Cord Clamping in Preterm Infants Born by Cesarean Section
The purpose of this study is to determine whether the umbilical cord milking in preterm infants born by cesarian section less than 34 weeks is more effective than delayed cord clamping to obtain higher levels of hemoglobin.
- Conditions
- Premature Infant, Umbilical Cord, Milking, Delayed Clamping
- Trial name
- NCT02187510
- Testing
- Umbilical cord milking, Delayed cord clamping
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Corporacion Parc Tauli
Rhesus Isoimmunization
Delayed Cord Clamping in Rhesus Disease of the Newborn
The objective of this clinical trial is to investigate the effects of delayed cord clamping on hyperbilirubinemia, the need for phototherapy, neonatal intensive care (NICU) admission
- Trial name
- NCT04600674
- Testing
- Delayed cord clamping, Early cord clamping
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Delayed Cord Clamping
Umbilical Cord Clamping: What Are the Benefits
Umbilical cord clumping consists in the binding of the umbilical cord by nipper to interrupt blood flow from placenta to foetus. Umbilical cord can be clamped within 30s or at least 1 min after birth.
- Trial name
- NCT03878602
- Testing
- Delayed umbilical cord clamping, Immediate umbilical cord clamping
- Where
- Italy
- Volunteers
- 142 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Delay Cord Clamping, Placental Trasfusion
Position at Birth,Placental Transfusion Volume and Cord Clamping
To compare the evolution of the infant's weight before delayed cord clamping (2 minutes after birth) as an indirect measure of the volume of placental transfusion in a group of healthy and fullterm newborns, placed at the level…
- Trial name
- NCT01497340
- Testing
- Position at introitus level, Position at Maternal Abdomen
- Where
- Argentina
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Salud Materno Infantil
Newborn Infant, Newborn Health
The Effect of Different Positions Given to the Newborn During Delayed Cord Clamping on Physiological Indicators and Comfort
During intrauterine life, the fetus is connected to the mother via the placenta; with birth, the extrauterine adaptation process begins.
- Conditions
- Newborn Infant, Newborn Health, Delayed Cord Clamping
- Trial name
- Cord Clamping (NCT07719751)
- Testing
- Prone position, Left side lying position
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mersin University
Anemia, Ferritin
Effect of Timing of Umbilical Cord Clamping on Haematological and Clinical Outcomes of Infants
In developing countries up to 50% of children become anemic by 12 months of age(1. Iron deficiency anemia is a major risk factor for neonatal and infantile mortality and morbidity in Pakistan.
- Conditions
- Anemia, Ferritin, Complications, Hemorrhage
- Trial name
- NCT01081977
- Testing
- Early Cord Clamping, Delayed Cord Clamping
- Where
- Pakistan
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Intrauterine Growth Restriction (IUGR), Oxidative Stress in Neonates
Intrauterine Growth Restriction and Intrauterine Fetal Death
This study investigated whether delaying the clamping of the umbilical cord after birth can reduce harmful oxidative stress in newborns, especially in those who did not grow well during pregnancy (intrauterine growth restriction…
- Conditions
- Intrauterine Growth Restriction (IUGR), Oxidative Stress in Neonates, Umbilical Cord Clamping Time
- Trial name
- NCT07031583
- Testing
- Delayed Umbilical Cord Clamping (DCC), Early Umbilical Cord Clamping (ECC)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Intraventricular Haemorrhage Neonatal, Death; Neonatal
Premature Infants Receiving Milking or Delayed Cord Clamping: PREMOD2
This study is being done to find out whether umbilical cord milking (UCM) is at least as good as or better than delayed cord clamping (DCC) to reduce bleeding in the brain or prevent death in premature newborns.
- Trial name
- PREMOD2 (NCT03019367)
- Testing
- Umbilical cord milking UCM, Delayed cord clamping DCC
- Where
- 18 sites in United States, Canada and 2 more
- Volunteers
- 1,201 people
- Sponsor
- Sharp HealthCare
Deferred Umbilical Cord Clamping
Physiological Effects of Deferred Cord Clamping
This is an observational study to see if at birth, flow of blood from a placenta to the baby can be estimated non-invasively using Doppler ultrasound and/or cutaneous perfusion measured using a novel PPG sensor.
- Trial name
- DoppCord (NCT01864421)
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Nottingham
Infant, Premature, Diseases
VentFirst Pilot: Ventilating Preterm Infants During Delayed Cord Clamping
Delayed clamping of the umbilical cord (DCC) has been shown to have some benefits for preterm infants. Initiation of breathing before cord clamping is also thought to be beneficial.
- Trial name
- NCT02391389
- Testing
- CPAP or PPV during DCC
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Virginia
NRDS
Impact of Delayed Cord Clamping and Minimally Invasive Surfactant Administration on Outcomes in Premature Infants Less Than 30 Weeks Gestation
Background: Preventing early exposure to invasive mechanical ventilation in premature infants is crucial for reducing the incidence of bronchopulmonary dysplasia (BPD) and improving overall outcomes.
- Trial name
- NCT07092319
- Testing
- deferred cord clamping
- Where
- China
- Volunteers
- 518 people
- Sponsor
- Peking University Third Hospital
PreTerm Birth, Intraventricular Hemorrhage
Deferred Cord Clamping Compared to Umbilical Cord Milking in Preterm Infants
For preterm infants, deferred cord clamping has been shown to improve both short term and long-term neonatal outcomes without an established harm for both the mother and her infant.The interference with resuscitative measures for…
- Trial name
- NCT02996799
- Testing
- Umbilical cord milking
- Where
- Saudi Arabia
- Volunteers
- 180 people
- Sponsor
- King Abdulaziz University
IVH- Intraventricular Hemorrhage, Extreme Prematurity
Delayed Cord Clamping With Oxygen In Extremely Low Gestation Infants
This study is being conducted to compare the incidence of preterm infants (up to 28+6 weeks GA) who achieve a peripheral oxygen saturation of 80 percent by 5 minutes of life (MOL) given mask CPAP/PPV with an FiO2 of 1.0 during…
- Conditions
- IVH- Intraventricular Hemorrhage, Extreme Prematurity, Hypoxia Neonatal, Hyperoxia
- Trial name
- DOXIE (NCT04413097)
- Testing
- Delayed Cord Clamping with Low Oxygen concentration, Delayed Cord Clamping with High Oxygen concentration
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- Sharp HealthCare
Newborn; Anemia, Umbilical Cord Problem
Supine vs Prone Position During Delayed Cord Clamping
This study is conducted to evaluate if the prone position of the newborn on the chest of his mother at birth before delayed cord clamping leads to better hematocrit and hemoglobin at 24-48 hours of life compared to supine…
- Trial name
- DCC (NCT03697967)
- Testing
- supine or prone position
- Where
- Canada
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Developmental Delay
18 Month Follow Up of Preterm Infants Enrolled in the Cord Clamping Study
The purpose of this study is to examine differences in the long-term effects of immediate versus delayed cord clamping at birth on developmental outcomes of our study infants at 18-22 months corrected age.
- Trial name
- 18mo (NCT01426698)
- Testing
- delayed cord clamping
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of Rhode Island
Intraventricular Hemorrhage
VentFirst: A Multicenter RCT of Assisted Ventilation During Delayed Cord Clamping for Extremely Preterm Infants
The purpose of this study is to determine whether providing ventilatory assistance prior to umbilical cord clamping influences the occurrence of intraventricular hemorrhage (IVH) in extremely preterm (EPT) infants, compared to…
- Trial name
- NCT02742454
- Testing
- Standard 30-60 Seconds Cord Clamping, VentFirst 120 Seconds Cord Clamping
- Where
- 12 sites in United States, Canada
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Placental Transfusion
Delivery Room Assistance With the Placental Circulation Intact
Preterm newborns receiving placental transfusion at birth (a volume of blood coming from the placenta towards the newborn till the cord is left unclamped) have better neonatal outcomes (in particular reduction of intraventricular…
- Trial name
- PCI-T (NCT02671305)
- Testing
- placental circulation intact, cord milking
- Where
- 8 sites in Italy
- Volunteers
- 212 people
- Sponsor
- University of Florence
Ductus Arteriosus
Effect of Umbilical Cord Milking Versus Clamping in Preterms on Cerebral Oxygenation and Ductus Arteriosus Closure
All patients will be subjected to the following: 1-Umbilical cord milking or delayed cord clamping according to the ranamization table 2 serial measurement of cerebral tissue oxygenation 3- serial echocardiography for ductus…
- Trial name
- NCT05922488
- Testing
- Umbilical cord milking, delayed cord clamping
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Bonding, Stress
Preterm DElayed Cord Clamping and Early Skin-to-Skin Contact: PreDECESS
The PreDECESS trial is a prospective study where that will evaluate a new method taking care of premature infants in gestational weeks 30+0 to 34+6 at birth.
- Conditions
- Bonding, Stress, Breastfeeding, Child Development
- Trial name
- PreDECESS (NCT05709392)
- Testing
- Delayed cord clamping and early skin-to-skin contact
- Where
- Sweden
- Volunteers
- 126 people
- Sponsor
- Ostergotland County Council, Sweden