Clinical trials: Delivery
Vision Disorders, Strabismus
Vision in Children Born to Opioid-dependent Methadone-maintained Mothers
The investigators will re-investigate 150 children studied extensively in the past. 100 of these children were born to mothers prescribed methadone during their pregnancy because of opiate dependency, and 50 were comparison…
- Conditions
- Vision Disorders, Strabismus, Nystagmus, Binocular Vision Disorder
- Trial name
- VINCH (NCT03603301)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- NHS Greater Glasgow and Clyde
Preterm Birth
E-health-supported Diagnostic and Intervention in Preterm Born Children and Their Families
The app-based diagnostic and support approach with a focus on mental and somatic symptoms is intended to strengthen the resilience of premature born children and families and to identify risk and resilience factors.The overall…
- Trial name
- NeoUp2 (NCT06939192)
- Testing
- Intervention Group (APP), Treatment as usual-Group (TAU)
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Patent Ductus Arteriosus, Prematurity
Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure
The primary objective is to evaluate the Patent Ductus Arteriosus (PDA) closure rate of early vs. late use of Ibuprofen (Ibu). The investigators believe that early use of Ibu will have a higher PDA closure rate than later use of…
- Trial name
- NCT00833365
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Utah
Infant, Premature, Congenital Heart Disease
Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus
Patent ductus arteriosus (PDA) is a common problem in the neonatal intensive care unit and can be secondary to prematurity or congenital heart disease (CHD).
- Conditions
- Infant, Premature, Congenital Heart Disease, Patent Ductus Arteriosus, Necrotizing Enterocolitis
- Trial name
- NCT03551600
- Testing
- Near-infrared spectroscopy (NIRS)
- Where
- 3 sites in United States
- Volunteers
- 64 people
- Sponsor
- University of Utah
Acquired Immunodeficiency Syndrome, HIV Infection
Genetically Modified Lymphocytes to Treat HIV-Infected Identical Twins - Study Modifications
Certain patients enrolled in NIH protocol 94-I-0206 at the Clinical Center may be eligible to participate in one or more of the following new options: Donor/recipient extension phase - Both the recipient (HIV-infected twin) and…
- Trial name
- NCT00001409
- Testing
- Interleukin-2
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Telemedicine, Emergency Medical Service
Audiovisual Consultations in Prehospital Emergency Care: Randomised Controlled Trial
This study investigates safety and efficacy of the use of audiovisual consultations of emergency medical service (EMS) doctor by paramedics for low urgency events in areas covered with paramedic crews only from emergency medical…
- Trial name
- Telemedicine (NCT04312321)
- Testing
- Mandatory phone call consultation, Mandatory audiovisual consultation
- Where
- Czechia
- Volunteers
- 600 people
- Sponsor
- Zdravotnicka Zachranna Sluzba Karlovarskeho Kraje, P.O.
Preterm Infants, Infant, Low Birth Weight
Effects of Early Yakson Touch and Kinesthetic Stimulation on the Development of High Risk Neonates
The role of physiotherapy interventions in treatment of high risk infants has not been established even after a number of studies.
- Trial name
- YTKS (NCT02815904)
- Testing
- Yakson touch, Conventional handling, Kinesthetic stimulation
- Where
- India
- Volunteers
- 28 people
- Sponsor
- Asir John Samuel
Food Allergies
Endophenotyping for Plant-based Food Allergy Diagnosis, Tolerance Biomarkers, and Mechanisms in Microneedle Immunotherapy
In relation to the prognosis of vegetable FA (VFA), in contrast to other food allergies (FA), which disappear naturally with time, VFA tends to persist into adulthood and to the appearance of new sensitizations to other…
- Trial name
- NCT06997432
- Testing
- Dietary intervention
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Social Communication Disorder, Autism
Feasibility Trial of Parent-delivered Social Communication Program
The Hanen Centre®'s More Than Words® (MTW) program is a globally used, parent coaching intervention delivered by speech-language pathologists (SLPs) to parents of children with social communication challenges, including those who…
- Trial name
- NCT06847347
- Testing
- More Than Words®
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Western University, Canada
Tuberculosis
Randomized Controlled Trial of Percutaneous and Intradermal BCG Vaccination.
An open label, randomized, controlled, equivalency trial to compare the efficacy of the percutaneous route of administration with the intradermal route of administration of Japanese (Tokyo) 172 BCG, in the prevention of…
- Trial name
- NCT00242047
- Testing
- Japanese (Tokyo) 172 Bacille Calmette Guerin (BCG).
- Where
- South Africa
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Parainfluenza, Virus Diseases
Safety of and Immune Response to Recombinant Live-Attenuated Parainfluenza Type 1 Virus Vaccine
Human Parainfluenza Virus Type 1 (HPIV1) is a leading cause of viral respiratory infections in children, the elderly, and those with compromised immune systems.
- Trial name
- NCT00641017
- Testing
- rHPIV1 84/del170/942A, Lot PIV1 #104A vaccine
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Premature Infant, Patent Ductus Arteriosus
Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.
The proposed research evaluates tissue oxygenation (StO2) as measured by resonance raman spectroscopy (RRS) in premature infants with and without patent ductus arteriosus (PDA).
- Conditions
- Premature Infant, Patent Ductus Arteriosus, Hemodynamic Instability
- Trial name
- NCT03277768
- Testing
- Resonance Raman Spectroscopy (RRS)
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Florida
Body Weight Changes, Feeding and Eating Disorders of Childhood
Adjusted Individual Oral Feeding for Improving Short and Long Term Outcomes of Preterm Infants
The authors hypothesize that adjusted individual feeding (AIF) for preterm infant starting from transition to oral feeding (33 weeks corrected age) will result in less episodes of apnea/bradycardia, early achievement of full oral…
- Conditions
- Body Weight Changes, Feeding and Eating Disorders of Childhood, Breast Feeding, Evoked Response Audiometry
- Trial name
- NCT01989871
- Testing
- Adjusted individual feeding
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Immunomodulation Effect
Effect of Autologous Cord Blood-mononuclear Cells Infusion on Immune Microenvironment in Infants Born Very Preterm in NICU
Multi-omics (analysis of peripheral blood immune cells subset, peripheral blood MNCs transcriptome, soluble inflammatory cytokine profile in blood and airway secretion, lung and gut microbiota, and the interaction) analysis was…
- Trial name
- NCT05087498
- Testing
- autologous cord blood mononuclear cells, normal saline
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Iron Overload, Oxidative Stress
Safety of Various Mode of Delivery of Iron Supplement on Iron Toxicity Markers in Preschool Children
The purpose of study is to evaluate and compare the effect of iron supplementation when given as iron tablet or fortified biscuit or combined with zinc in the form of tablet on morbidity and iron toxicity markers among children…
- Trial name
- NCT00980421
- Testing
- Iron Supplementation
- Where
- India
- Volunteers
- 240 people
- Sponsor
- Annamalai University
Infant Respiratory Distress Syndrome
Umbilical Vein Needle Catheterization for Endotracheal Intubation.
The investigators describe a simple and efficient method to give a premedication in the delivery room, using the umbilical vein, directly punctured through Wharton's jelly.
- Trial name
- Intubation (NCT03359993)
- Testing
- Premedication of intubation
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Hôpital NOVO
Prenatal Care, Premature Birth
Biological Markers of Disease in the Prediction of Preterm Delivery, Preeclampsia and Intra-Uterine Growth Retardation: A Longtitudinal Study
Preterm delivery, preeclampsia and intrauterine growth restriction are leading causes of perinatal morbidity and mortality. Efforts to treat these syndromes have not been effective, most likely becuase these obstetric…
- Trial name
- NCT00340899
- Where
- Chile
- Volunteers
- 19,134 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cystinuria
TCUPS- Tolvaptan Use in Cystinuria and Urolithiasis: A Pilot Study
The goal of this research project is to establish that in short-term use, tolvaptan is a safe and potentially effective new therapy for cystinuria, by conducting a short-term pilot study of the safety and tolerability of this…
- Trial name
- TCUPS (NCT02538016)
- Testing
- Tolvaptan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Caleb Nelson
Premature Birth
A Randomized Controlled Trial of Impact of Wearable, Wireless Breast Pumps on Frequency and Efficacy of Milk Expression in Mothers of Premature Infants
A randomized controlled trial of impact of wearable, wireless breast pumps on how often and how much milk mothers of premature infants can pump.
- Trial name
- MTMM (NCT06723067)
- Testing
- Wearable wireless breast pump
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Texas at Austin
Premature Birth
ADMA and Mechanical Ventilation in Preterm Infants
The purpose of this study is to study the relation between mechanical ventilation and ADMA concentrations at birth.
- Trial name
- NCT00460044
- Volunteers
- 35 people
- Sponsor
- Amsterdam UMC, location VUmc
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.