Clinical trials: Delivery Complication
Premature Birth
A Randomized Controlled Trial of Impact of Wearable, Wireless Breast Pumps on Frequency and Efficacy of Milk Expression in Mothers of Premature Infants
A randomized controlled trial of impact of wearable, wireless breast pumps on how often and how much milk mothers of premature infants can pump.
- Trial name
- MTMM (NCT06723067)
- Testing
- Wearable wireless breast pump
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Texas at Austin
Trichomonas Vaginalis, Urethritis
Study to Improve Partner Services for STD Prevention
The goal of this study was to examine the efficacy of patient-delivered partner treatment (PDPT) compared to standard partner referral (PR) and booklet enhanced partner referral (BEPR).
- Trial name
- NCT00207467
- Testing
- Patient-delivered partner treatment, Booklet-enhanced partner referral
- Where
- 2 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Centers for Disease Control and Prevention
Continuous Renal Replacement Therapy (CRRT), Acute Kidney Injury
Insights Into the Continuous Renal Replacement Therapy to Critical Ill Patients
This is a multinational, prospective, observational study designed to characterize patient demographics, prescription parameters, and process measures of continuous renal replacement therapy (CRRT) in intensive care units (ICUs)…
- Conditions
- Continuous Renal Replacement Therapy (CRRT), Acute Kidney Injury, Renal Dialysis, Critical Illness
- Trial name
- iCRRT (NCT07365111)
- Testing
- continuous renal replacement therapy
- Where
- Canada
- Volunteers
- 100,000 people
- Sponsor
- University of Alberta
Fanconi Anemia Complementation Group A, Fanconi Anemia
Long-Term Follow-up of Subjects With Fanconi Anaemia Subtype A Treated With ex Vivo Gene Therapy
This is a long-term safety and efficacy follow-up study for subjects with Fanconi Anaemia Subtype A who have been treated with ex vivo gene therapy on the FANCOLEN-I trial.
- Trial name
- NCT04437771
- Testing
- Safety and efficacy assessments
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- Rocket Pharmaceuticals Inc.
Premature Birth, Electrical Impedance Tomography (EIT)
Lung Volume Changes in Stable Preterm Infants Positioned in Car Seats
Premature infants (infants born <37 weeks' gestational age) are discharged from the hospital and transported home in car seats designed for term babies. The safe transport of these premature infants is an important concern.
- Conditions
- Premature Birth, Electrical Impedance Tomography (EIT), Lung Volume, Car Seat Transition for At-risk Infants
- Trial name
- CarSeat (NCT06724601)
- Testing
- Electrical Impedance Tomography
- Where
- Switzerland
- Volunteers
- 51 people
- Sponsor
- University of Zurich
Pre-Term
I-InTERACT Preterm
Open pilot of a brief online parenting-skills intervention for young children ages 3-8 who were born very preterm (< 32 weeks gestational age).
- Trial name
- NCT05282628
- Testing
- Building Better Brains and Behavior program (B4 Preterm)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Respiratory Distress Syndrome
Medium vs Low Oxygen Threshold for the Surfactant Administration
The aim of this study will be to assess the better fraction inspired oxygen (FiO2) threshold for the surfactant treatment in preterm infants with respiratory distress syndrome (RDS) randomized to receive exogenous surfactant at…
- Trial name
- NCT04199364
- Testing
- Poractant Alfa 80 mg/mL Intratracheal Suspension
- Volunteers
- 200 people
- Sponsor
- Virgilio Paolo Carnielli
Retinopathy of Prematurity Both Eyes, Retinal Disease
VEGF Concentrations After Intravitreal Bevacizumab vs Ranibizumab as a Treatment for Type 1 ROP
The Retinopathy of Prematurity (ROP) is one of the leading causes of blindness on the pediatric age worldwide. This pathology is characterized for arrest of the normal vascular and neuronal retina that because of pathological…
- Conditions
- Retinopathy of Prematurity Both Eyes, Retinal Disease, Premature Birth, Eye Diseases
- Trial name
- NCT03148132
- Testing
- Bevacizumab Injection, Ranibizumab Ophthalmic
- Where
- Mexico
- Volunteers
- 16 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Neurologic Manifestations, Premature Birth
The Neu-Prem Trial: Neuromonitoring of Preterm Newborn Brain During Birth Resuscitation
The purpose of this study is to characterize the normal brain function of premature infants (23 to 31+6 weeks GA) during birth transition and through the first 72 hours of life.
- Conditions
- Neurologic Manifestations, Premature Birth, Hypoxia-Ischemia, Brain
- Trial name
- Neu-Prem (NCT02605733)
- Testing
- EEG, NIRS
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Sharp HealthCare
Newborn Respiratory Distress, Preterm Infant
Short Term Effects of Synchronized vs. Non-synchronized NIPPV in Preterm Infants.
Comparing the cardio-respiratory adaptation and differences to non invasive ventilation techniques, nasal intermittent positive pressure ventilation (NIPPV) non synchronized vs synchronized (SNIPPV) in preterm newborns…
- Trial name
- SyncNIV (NCT03289936)
- Testing
- NIPPV, SNIPPV
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Premature Birth
Cardiovascular Health Assessment of Preterm- and TERm-born Children
The purpose of the CHAPTER study is to help understand how complications during pregnancy, such as preterm birth, affect how childrens' hearts and blood vessels develop.
- Trial name
- CHAPTER (NCT05698836)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Oxford
Parenteral Nutrition, Necrotizing Enterocolitis
Neurodevelopment and Neuroimaging in Parenterally-fed Infants and Young Children
Manganese (Mn) is an essential metal required for normal growth and development. However, exposure to high Mn levels can be toxic to the brain.
- Conditions
- Parenteral Nutrition, Necrotizing Enterocolitis, Digestive System Abnormalities, Cholestasis
- Trial name
- NCT00392730
- Testing
- Remove Mn from PN if evidence of increased brain Mn on MRI
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Preterm, General Movements
Fidgety Movements of Preterm Neonates Included in COSGOD III
The evidence on the effects of clinical care with cerebral NIRS (Near-infrared spectroscopy) monitoring on short term neurological outcome, displayed by fidgety movements between six to 20 weeks post term, are still uncertain.
- Conditions
- Preterm, General Movements, Fidgety Movements, Near Infrared Spectroscopy
- Trial name
- Figdety_Ms (NCT06105333)
- Testing
- standard care plus cerebral oxygen saturation monitoring with a dedicated treatment guideline
- Where
- 2 sites in Austria
- Volunteers
- 183 people
- Sponsor
- Medical University of Graz
Full Enteral Nutrition, the Day and Night Cycle
The Effect of Day-Night Cycle on the Transition Time to Full Enteral Feeding in Preterm Newborns Receiving Oropharyngeal Colostrum
The aim of this study was to examine the effect of the day-night cycle on the transition time to full enteral nutrition in premature infants receiving oropharyngeal colostrum.
- Trial name
- PRETERM (NCT06883903)
- Testing
- day-night cycle application, routine practice
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Biruni University
Prematurity, Dysphagia
Swallowing and Oral Sensory Complaints in Preterm Children
Objective Preterm children face an elevated risk of neurodevelopmental delays and feeding difficulties, necessitating early assessment to support their long-term health.
- Conditions
- Prematurity, Dysphagia, Feeding Disorder of Infancy or Early Childhood
- Trial name
- NCT06881381
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people
- Sponsor
- Medipol University
Placenta Previa
Management Of Placenta Previa Cases And Determination Of Hospitalization Criteria
Placenta previa cases are one of the difficult groups of patients to manage in modern obstetrics. When the literature is evaluated extensively, no clear information can be seen especially in terms of hospitalization time.
- Trial name
- NCT04264234
- Testing
- Vaginal Ultrasonography, Magnetic Resonance Imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Ege University
Premature Infant Disease, Respiratory Insufficiency
Flow-synchronized Nasal IMV in Preterm Infants
The use of non-invasive methods of respiratory support to reduce complications of prolonged invasive mechanical ventilation in preterm infants has increased.
- Trial name
- NCT02085499
- Testing
- non-synchronized NIMV, Synchronized NIMV
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Miami
Preterm Infant
AEEG in Pre-term Infants
Amplitude integrated encephalography (aEEG) is a monitor that measures brain activity by attaching leads to a baby's head, and is used routinely in term babies who have brain injury because of a difficult birth.
- Trial name
- AEEG (NCT04008498)
- Testing
- AEEG brain monitoring
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis
National Registry of Rare Kidney Diseases
The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research.
- Conditions
- Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis
- Trial name
- RaDaR (NCT06065852)
- Where
- United Kingdom
- Volunteers
- 35,000 people
- Sponsor
- UK Kidney Association
Pregnancy, Stillbirth
Zambian Preterm Birth Prevention Study
This prospective non-intervention cohort study will enroll women in the first or early second trimester of pregnancy and follow them through delivery (or end of pregnancy) and 1 year postpartum.
- Conditions
- Pregnancy, Stillbirth, Preterm Birth
- Trial name
- ZAPPS (NCT02738892)
- Where
- 2 sites in Zambia
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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