Clinical trials: Dental
Dental Caries, Restoration Defects
Repair Versus Replacement of Failed Restorations in Primary Teeth
Dental caries affect approximately 573 million children globally, and the management of failed restorations is a frequent clinical issue in pediatric dentistry.
- Conditions
- Dental Caries, Restoration Defects, Primary Teeth
- Trial name
- NCT07813065
- Testing
- Repair of Failed Restoration, Replacement of Failed Restoration
- Where
- Brazil
- Volunteers
- 382 people
- Sponsor
- University of Sao Paulo
Irreversible Pulpitis, Caries,Dental
Evaluation of Antimicrobial, Post Operative Pain of Cinnamon Extract Versus Sodium Hypochlorite Irrigant Following Pulpectomy of Primary Teeth
The aim of the study is to evaluate effectiveness of cinnamon extract versus sodium hypochlorite as root canal irrigant for in pulpectomy of primary teeth in reduction of bacterial count .
- Trial name
- NCT05860712
- Testing
- Irrigation
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periapical Periodontitis
Periapical Healing After One or Two-visits to Endodontic Treatment in Adolescents Patients
The main objective of this study is the prevention and repair of apical periodontitis in lower molars with pulp necrosis after the execution of endodontic treatment in one or two visits in adolescent patients.
- Trial name
- PHAP (NCT01312194)
- Testing
- Root canal therapy in one visit, Root Canal Therapy in two-vist
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Caries, Dental, Caries Class I
Caries Sealing Using Giomer and Glass Ionomer Cement With or Without Silver Diamine Fluoride
The purpose of this study is to evaluate and compare the clinical performance of Giomer and GIC restorations with and without SDF on caries sealing of primary molar teeth
- Trial name
- NCT03872986
- Testing
- SDF, Giomer, GIC
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
Clinical Performance of Glass Ionomer Versus Resin Composite Restorations
The aim of this randomised-controlled, single-blind, split-mouth, and single-centre clinical trial was to evaluate the 2-year clinical performances of a high-viscosity glass ionomer and nanohybrid composite resin in occlusal…
- Trial name
- NCT04488380
- Testing
- dental restoration
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Dental Pain
Dental Pain Study of Analgesics in Patients Undergoing Molar Removal
Accessing the efficacy and safety of pregabalin when used alone and in combo with acetaminophen in a dental pain model. To test whether pre-operative dose of pregabalin increases the time to significant post-operative pain (NRS ≥…
- Trial name
- NVK009-0001 (NCT03652818)
- Testing
- Pre-Op pregabalin, Post-Op pregabalin
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Molar Incisor Hypomineralization
Silver Diamine Fluoride Modified Restoration In Treating Hypomineralized First Permanent Molar.
A randomized clinical trial to compare silver modified glass ionomer restorations to non silver glass ionomer restorations in hypo-mineralized first permanent molars in children and to measure the amount of wear of restoration in…
- Trial name
- NCT05931822
- Testing
- Silver Diamine Fluoride 38%, fluoride varnish
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Molar Incisor Hypomineralization
Restorative Treatment in First Molars Affected by Molar-Incisor Hypomineralization
The restorative management of molars with Molar-Incisor Hypomineralization (MIH) represents a challenge in the clinical practice with high failure rate.
- Trial name
- NCT02717286
- Testing
- restorative
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Paraná
Pain, Needle Phobia
Pain Perception of Needle-free System
The purpose of this study is to evaluate and compare the pain perception associated with a needle-free injection system( Comfort-In) and dental injection method in filling and pulpotomy treatments
- Conditions
- Pain, Needle Phobia, Anxiety, Dental Fear
- Trial name
- NCT04653974
- Testing
- Needle-free injection
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Healthy
Reducing Sugared Fruit Drinks in Alaska Native Children
This study in Alaska will test whether providing sugar-free alternatives to sugared fruit drinks and introducing education and social support will help families and children to reduce the amount of sugared fruit drinks consumed…
- Trial name
- NCT05219448
- Testing
- Education and self-efficacy coaching
- Where
- United States
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dental Caries
Effectiveness of ART and Conventional Treatment - Practice-based Clinical Trial
Background: Dental caries is still a public health problem among Brazilian children and doubts still exist regarding the most effective restorative technique.
- Trial name
- NCT02568917
- Testing
- Atraumatic Restorative Treatment - Ketac Molar Easy Mix, Conventional Restoration - Composite Resin (Bulk Fill)
- Where
- Brazil
- Volunteers
- 800 people
- Sponsor
- University of Sao Paulo
Dental Plaque (Diagnosis), Deep Learning
Microbial Dental Plaque Analysis in Young Permanent Teeth Using Deep Learning
Background: Dental plaque contributes to a number of common oral conditions such as caries, gingivitis, and periodontitis. As a result, detection and management of plaque is of great importance for the oral health of individuals.
- Trial name
- NCT06603233
- Testing
- The Difference Between The AI Model and Dentists Group, Deep Learning Models
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Enamel Hypomineralization, Tooth Erosion
Hydroxyapatite Toothpastes and Enamel Remineralization:
This randomized controlled clinical trial aims to evaluate the efficacy of two commercially available toothpastes containing hydroxyapatite in the remineralization of early enamel lesions.
- Trial name
- HEREMI (NCT07069218)
- Testing
- Biorepair® Total Protection Plus Toothpaste, Bioniq® Toothpaste
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Dental Diseases
School Oral Health Intervention in Nepal
Oral health problems in school children are highly prevalent in Nepal. The investigators designed oral health counseling and promotion intervention in Kaski district of Nepal for six months.
- Trial name
- NCT05811650
- Testing
- Oral Health Counseling and promotion
- Where
- Nepal
- Volunteers
- 669 people, healthy volunteers welcome
- Sponsor
- Cyberjaya University College of Medical Sciences
Apgar Score, Motor Coordination or Function; Developmental Disorder
Effect of Tobacco Use on the Health of the Newborn up to 24 Months.
There is scientific evidence suggesting that tobacco use during pregnancy is associated with several adverse effects in newborns, including low birth weight, respiratory complications, severe neonatal morbidity, perinatal death…
- Conditions
- Apgar Score, Motor Coordination or Function; Developmental Disorder, Lactation, Weight Control
- Trial name
- ETUHeNewBorn (NCT07427706)
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Dental Anxiety, Behavior, Child
Preferences About Personal Protective Equipment
Personal protective equipment (PPE) gained importance during the Coronavirus Disease 2019 (COVID-19) pandemic, which is a global hot topic for all healthcare staff.
- Conditions
- Dental Anxiety, Behavior, Child, Preference, Patient
- Trial name
- NCT04933578
- Testing
- Dental anxiety scales
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Dental Caries
CAMBRA - PBRN Caries Management By Risk Assessment In A Practice-Based Research Network
The goal of this project is to create a Practice Based Research Network with 30 researcher dentists calibrated on the administration of a caries risk assessment and the treatment modalities recommended based on the caries risk…
- Trial name
- CAMBRA-PBRN (NCT01176396)
- Testing
- Caries prevention active intervention, control treatment
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries
Evaluation of a Low Fluoride Dentifrice for Caries Control
The aim of this randomized clinical trial is to evaluate the effect of pH and fluoride concentration in liquid dentifrices in the control of dental caries in early childhood, in non-fluoridated area.
- Trial name
- NCT01623362
- Testing
- Low-fluoride acidic dentifrice, conventional dentifrice, neutral pH and low-fluoride dentifrice
- Where
- Brazil
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Cooperative Behaviour, Dental Anxiety
Efficacy of Film Modelling in Paediatric Dentistry
The aim of this study is to evaluate the effect of Filmed modelling in comparison with commonly used Tell-Show-Do technique on the anxious and cooperative behaviour of 4-6 years old children during dental practice.
- Trial name
- NCT01908127
- Testing
- tell- show- do, film modelling, injection of local anesthesia solution
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zahedan University of Medical Sciences
Autism Spectrum Disorder (ASD
Effectiveness of Clown Therapy in Facilitating Dental Visits for Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by difficulties in verbal and non-verbal communication and social interaction, as well as repetitive and stereotyped behaviors.
- Trial name
- NCT07906288
- Testing
- Familiarization sessions using clown therapy, Familiarization sessions with conventional methods
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- University of Milan
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