Clinical trials: Dental Caries Prevention
Dental Caries
Effective Fluoride Concentration In Toothpaste For Dental Caries Prevention
to identify the Effective Fluoride Concentration In Toothpaste For Dental Caries Prevention after 18 months of randomized controlled trial.
- Trial name
- DMFT (NCT02016001)
- Testing
- toothpaste 1 with maximum fluoride concentration, toothpaste 2 with 1000 ppm of fluoride
- Where
- Pakistan
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Dental Caries
Use of Fissure Sealants on Primary Molars
Sealants have been shown to be the most effective caries preventive measure in permanent dentition. Sealants of the primary molars soon after they erupt would reduce the total caries experience of the primary teeth of the…
- Trial name
- NCT01438866
- Testing
- Fissure sealant, Fissure sealants and fluoride varnish
- Where
- Kuwait
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Caries,Dental
Ozone Application Before Fissure Sealants
Decay is a multifactorial infective degenerative disease of hard dental tissues, caused by Streptococcus mutans and Lactobacillus forming the bacterial biofilm of teeth surfaces.
- Trial name
- NCT04040920
- Testing
- Ozone, Pits and fissure sealants
- Where
- Italy
- Volunteers
- 67 people
- Sponsor
- IRCCS Burlo Garofolo
Early Childhood Caries, Dental Caries in Children
Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life
There is still a need for the assessment of different minimal intervention strategies and treatments focusing on the prevention and arrest of carious lesions of primary molars The evidence-based clinical practice guideline on…
- Conditions
- Early Childhood Caries, Dental Caries in Children, Dental Caries Extending Into Dentin, Dental Caries
- Trial name
- NCT05772039
- Testing
- Topical application of 38% Silver Diammine Fluoride Solution, Topical application of 5% Sodium Fluoride with functional Tricalcium phosphate Varnish
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Universiti Sains Malaysia
Caries, Dental
Prevention of Transmission of Bacteria That Cause Cavities From Mothers to Their Children
The purpose of this study is to control the levels of bacteria that causes cavities in mothers by a combination of treatments that include fluoride and chlorhexidine varnishes and xylitol-chewing gum before the appearance of…
- Trial name
- NCT00066040
- Testing
- Cervitec chlorhexidine varnish, Duraphat fluoride varnish, xylitol gum from Fennobon, Finland
- Where
- Brazil
- Volunteers
- 280 people
- Sponsor
- New York University
Autism Spectrum Disorder, Dental Caries
Using Video Modeled Social Stories to Improve Oral Hygiene in Children With Autism Spectrum Disorder
We hypothesize that oral hygiene habits in children 8-12 years of age can be improved using video format Social Story intervention techniques.
- Trial name
- NCT02003820
- Testing
- video modeled social story
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Yale University
Dental Caries
Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser
The objective of this clinical study is to evaluate whether the use of the new CO2 - 9.3μm short-pulsed laser increases the caries resistance of occlusal pit and fissure surfaces in patients in addition to fluoride therapy.
- Trial name
- LaserFissure (NCT02357979)
- Testing
- Laser, Fluoride
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries
Effectiveness of Fissure Sealant and Topical Fluoride Application in Preventing Dental Caries
Nearly half of the 12-year-old children in China have dental caries (tooth decay) and most of the lesions are in the fissures of the first permanent molars.
- Trial name
- NCT01446107
- Testing
- placement of fissure sealant, fluoride varnish, silver fluoride
- Where
- China
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Prevention of Dental Caries
Effect of Bioactive Glass Varnish on Salivary Parameters in Children: Randomized Controlled Trial
This study is a two-arm parallel randomized controlled trial led by Principal Investigator Inas Karawia at the Faculty of Dentistry, designed to evaluate and compare the short-term (immediatly) and sustained (over 6 months)…
- Trial name
- NCT07875387
- Testing
- Bioactive glass topical varnish, Fluoride varnish
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Dental Caries
Fluoride Varnish For Childsmile Nursery School Attenders
The study will compare the effectiveness of Duraphat® fluoride varnish in preventing any further dental decay among 3-4 year old children in nursery schools.
- Trial name
- PT@3 (NCT01674933)
- Testing
- Duraphat® Fluoride Varnish, treatment as usual
- Where
- 4 sites in United Kingdom
- Volunteers
- 1,610 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Dental Caries
Oral Alkali Production and Caries Prevention in Children (Longitudinal)
The fact that dental caries remains a major public health problem mandates that oral-health researchers explore new strategies for assessment of caries risk, as well as for caries prevention and management.
- Trial name
- NCT02398695
- Testing
- Oral Samples
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- University of Florida
White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory Setting
The goal of this clinical trial is to assess the efficacy of "Icon® resin infiltration" and "VanishTM XT varnish" in restoring the appearance of white spot lesions WSLs in healthy children affected with anterior white spot…
- Conditions
- White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Enamel Hypomineralization
- Trial name
- RI (NCT06696105)
- Testing
- Resin infiltration, Vanish XT varnish (resin modified glass ionomer restoration)
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Caries,Dental
Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars
Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries…
- Trial name
- NCT06826456
- Testing
- sub-ablative Er,Cr:YSGG laser, Fluoride varnish application
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Decay
Effect of Therapeutic Measures in Dental Caries Reduction in Children With Primary Dentition From Medellín City
The propouse of this study is to evaluate some combined preventive measures, of easy application in children under 6 years old as education, brush teeth, fluoride free tooth paste,fluoridated tooth paste, professional cleaning…
- Trial name
- NCT00475618
- Testing
- topical fluoride varnish application., professional cleaning, No fluoride toothpaste
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- CES University
Dental Caries in Children
Efficacy and Safety Evaluation of Anti-Caries Varnish
The purpose of the study is to determine the efficacy \& safety of Advantage Anti-Caries Varnish for primary prevention. The objectives are: 1) To determine if Advantage Anti-Caries Varnish (test varnish) is superior to an active…
- Trial name
- NCT04947527
- Testing
- Test varnish
- Where
- United States Minor Outlying Islands
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Dental Caries in Children
The Effectiveness of Dental Health Home Visits on Caries Prevention in Young Children
Tooth decay affects 75% of Malaysian preschool children, most of which remain untreated. Untreated decay can cause pain, and impair nutritional status and physical growth.
- Trial name
- NCT04885348
- Testing
- Intervention Group (Dental Home Visits + Dental Home Education Leaflets), Control Group (Dental Home Education Leaflets)
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Ministry of Education, Malaysia
Dental Caries in Children, Cariostatic Agent
Cariostatic and Remineralizing Effects of Three Different Dental Varnishes
This study is a randomly, controlled, prospective in vivo study. The objective of this study is: To evaluate the cariostatic and re-mineralizing effects of Nano silver fluoride, Nano Hydroxyapatite and sodium fluoride varnishes…
- Conditions
- Dental Caries in Children, Cariostatic Agent, Resistance, Dental Caries, Fluoride Varnishes
- Trial name
- NCT04887389
- Testing
- Nano Silver Fluoride varnish, nano-hydroxyapatite varnish, sodium Fluoride Varnish
- Where
- Egypt
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Nisreen Ibrahim khan
Dental Caries
A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children
The objective of this study is to assess the safety and to evaluate the anti-caries efficacy of COL101 (arginine) non-fluoride dentifrices compared to a 0.24% sodium fluoride dentifrice in 10-14 year-old children over a one year…
- Trial name
- NCT04750902
- Testing
- 0.24% Sodium Fluoride Dentifrice, 1.5% Arginine Dentifrice, 4.0% Arginine Dentifrice
- Where
- 9 sites in United States, Puerto Rico
- Volunteers
- 2,025 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Caries, Fluor
Efficacy of Fluor Protector S in the Prevention in Adolescents
Purpose of the study is to evaluate the effectiveness of Fluor Protector S in preventing tooth decay in adolescents and to isolate factors that reduce its effectiveness.
- Trial name
- NCT03720379
- Testing
- Fluor Protector S
- Where
- Poland
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Caries,Dental, Tooth Decay
KAP of Dental Practitioners Regarding CRA
The aim of the study is to evaluate the knowledge, attitude, and practice of a group of dental practitioners from Cairo and Riyadh regarding caries risk assessment and management.
- Conditions
- Caries,Dental, Tooth Decay, Tooth Diseases
- Trial name
- NCT05792215
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Cairo University