Clinical trials: Dentin Sensitivity
Sensitive Dentin, Hypomineralization Molar Incisor
BIOSILITACE AS A DESENSITIZING AGENTIN HMI
Molar-Incisor Hypomineralization (MIH) is a qualitative enamel defect caused by systemic hypomineralization that affects one to four first permanent molars, and may or may not involve incisors.
- Conditions
- Sensitive Dentin, Hypomineralization Molar Incisor, Pain
- Trial name
- BDAHMI (NCT07080645)
- Testing
- Pain Relieving, topical application
- Where
- 2 sites in Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo
Tooth Demineralization, Tooth Sensitivity
Graphene-Reinforced CAD/CAM Restorations for MIH-Affected Molars in Adolescents: A Prospective Clinical Study
This study evaluates the clinical performance, marginal integrity, surface wear, color stability, and postoperative sensitivity of graphene-reinforced CAD/CAM indirect restorations (inlays, onlays, overlays) in molars affected by…
- Conditions
- Tooth Demineralization, Tooth Sensitivity, Enamel Mineralization Disorders, Tooth Sensitivity After Composite Restorations
- Trial name
- NCT07329244
- Testing
- Graphene-reinforced CAD/CAM polymer (G-CAM®)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Dentin Hypersensitivity
Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice
The aim of this clinical study is to demonstrate the superior antihypersensitivity efficacy of a novel stannous fluoride (SnF2) and potassium nitrate (KNO3) dentifrice (Investigational Product), compared to SnF2 only, KNO3 only…
- Trial name
- NCT07215767
- Testing
- Stannous fluoride and Potassium nitrate Dentifrice, Stannous fluoride Dentifrice, Potassium nitrate Dentifrice
- Where
- 3 sites in United States
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Hypersensitivity, Active Dental Caries
Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth
This observational cohort study aims to evaluate the short-term (3 months) efficacy of the standard fluoride therapy in the German National Health System for managing hypersensitive carious lesions in primary teeth (fluoride…
- Trial name
- NCT04804423
- Testing
- 38% Silver Fluoride and Potassium Iodide solution (generic name; Riva Star®), Sodium fluoride varnish (generic name; Duraphat®)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Medicine Greifswald
Hypomineralization Molar Incisor, Hypersensitivity Dentin
Photobiomodulation and New Restorative Material for Teeth With MIH on Control of Hypersensitivity and Longevity
Introduction: Molar incisor hypomineralization (MIH) is a qualitative defect of enamel development that occurs in the mineralization phase. MIH affects one or more permanent molars and, occasionally, permanent incisors.
- Trial name
- NCT06538142
- Testing
- Photobiomodulation + Restoration with Self-cure Composite Resin, Restoration with Self-cure Composite Resin, Photobiomodulation + Restoration with Photopolymerizable Bulk-fill Composite Resin
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Molar-Incisor Hypomineralization (MIH), Pulp Disease, Dental
Assessment of Inflammatory Biomarkers in Molar-Incisor Hypomineralization-Affected First Permanent Molars
Molar-Incisor Hypomineralization (MIH) is a qualitative developmental defect of enamel primarily affecting the permanent first molars and often incisors. The global prevalence of MIH ranges from 2.9% to 44%.
- Conditions
- Molar-Incisor Hypomineralization (MIH), Pulp Disease, Dental, Inflamation
- Trial name
- NCT07008599
- Testing
- Pulpal Blood Sample
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people
- Sponsor
- Marmara University
Sensitivity, Tooth
Evaluation of Gluma Desensitizer in Post-treatment Sensitivity in Posterior Composite
To evaluate the effect of Gluma desensitizer in controlling immediate post-treatment sensitivity in posterior occlusal composite restorations.
- Trial name
- NCT04248803
- Testing
- GLUMA (Kulzer GmbH, Germany) desensitizing agent
- Where
- India
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- Tamil Nadu Dr.M.G.R.Medical University
Dentine Hypersensitivity
Three Different Topically Applied Materials as Non-invasive Treatment of Sensitivity in Permanent Teeth With Molar Incisor Hypomineralization
This clinical study main goal is to investigate the effectiveness of nano hydroxy apatite crystal varnish and potassium nitrate gel as a non invasive approach in managing Dentin Hypersensitivity in MIH-affected teeth.
- Trial name
- NCT07056855
- Testing
- nano hydroxy apatite varnish Intervention (1), Potassium Nitrate Gel, Varnishes, Fluorid
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentine Hypersensitivity, Tooth Erosion
The Effects of Mouthguard and Desensitizing Toothpaste in Reducing Dental Hypersensitivity
Tooth hypersensitivity due to dental erosion is one of the most common problem related to swimming in improper pH chlorinated pools.
- Trial name
- NCT03515902
- Testing
- mouthguard, mouthguard with desensitizing toothpaste
- Where
- Thailand
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Dental Pulp Exposure, Postoperative Pain
Diode Laser-Assisted Direct Pulp Capping Trial
This randomized controlled clinical trial evaluates whether adjunctive 808-nm diode laser therapy after direct pulp capping reduces postoperative pain and dentin hypersensitivity compared with conventional Biodentine treatment.
- Conditions
- Dental Pulp Exposure, Postoperative Pain, Dentin Hypersensitivity
- Trial name
- NCT07593508
- Testing
- Biodentine, 808-nm Diode Laser
- Where
- Vietnam
- Volunteers
- 56 people
- Sponsor
- Hue University of Medicine and Pharmacy
Dentin Hypersensitivity
The Efficacy of a Toothpaste to Reduce Sensitivity
Hypersensitivity
- Trial name
- NCT00763269
- Testing
- Triclosan, Silicon dioxide, fluoride, Triclosan, fluoride
- Where
- United States
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentin Sensitivity, Xerostomia
Effect of a Self-adhering Material in Dental Hypersensitivity
Aim: To compare the desensitizing capacity of Vertise Flow™ (VF), a new self adhering material, in the treatment of dentine hypersensitivity (DH) in patients who are xerostomic due to radiotherapy for head and neck cancer.
- Trial name
- NCT02766127
- Testing
- Veritise Flow, Universal Dentin Sealant, Clearfil Protect Bond
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Università degli Studi di Sassari
Hypomineralization Molar Incisor
Laser Therapy and Flouride Therapy in Desensibilization Hypomineralized Teeth
To investigate the efficacy of laser therapy associated with fluorotherapy in the desensibitization of hypomineralized teeth in children 8 to 12 years of age. A randomized blinded clinical trial will be conducted.
- Trial name
- LTAFTIDHT (NCT03823170)
- Testing
- Laser therapy, Fluorotherapy, Laser therapy and Fluorotherapy
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universidade Ceuma
Enamel Hypomineralization, Tooth Erosion
Hydroxyapatite Toothpastes and Enamel Remineralization:
This randomized controlled clinical trial aims to evaluate the efficacy of two commercially available toothpastes containing hydroxyapatite in the remineralization of early enamel lesions.
- Trial name
- HEREMI (NCT07069218)
- Testing
- Biorepair® Total Protection Plus Toothpaste, Bioniq® Toothpaste
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Dentin Sensitivity, Molar Incisor Hypomineralization
MIH and Hypersensitivity in Children
The aim of this study was to evaluate the efficacy of the association of casein phosphopeptide plus amorphous calcium phosphate (CPP-ACPF) mousse and photo-bio-modulation therapy (PMBT) (diode laser, RAFFAELLO 980 BIO - Dental…
- Trial name
- NCT05705037
- Testing
- CPP-ACPF, PBMT, CPP-ACPF+PBMT
- Where
- Italy
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Brescia
Caries, Dental, Tooth Decay
Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations
This is a clinical study evaluating a new dental product called Solventum™ Vitrebond™ Pulp Protect Liner/Base. This new product is designed to be used as a liner or base between the tooth and the dental filling, as well as for a…
- Conditions
- Caries, Dental, Tooth Decay, Dental Decay, Tooth Sensitivity
- Trial name
- NCT07261137
- Testing
- Vitrebond™ Pulp Protect Liner/Base, Vitrebond™ Plus (comparator)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Solventum US LLC
Adhesion
Dentin Treatments for Restorations of Cervical Lesions Non-Carious
The surface of non-carious cervical lesions (LCNC) is a challenge to adhesive systems, it presents a dentin layer sclera hypermineralized, presence of bacteria and lack of mechanical retention, so this study aimed to evaluate the…
- Trial name
- NCT02434601
- Testing
- Treatment of Dentin Surface, Dentin Surface, Treatment
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Enamel Hypoplasia, Molar-Incisor Hypomineralization (MIH)
Clinical Comparison of CAD/CAM Nanohybrid Composite and Hybrid Ceramic Overlays in Children With Molar-Incisor Hypomineralisation
This clinical study was conducted to compare two different dental materials used in the treatment of children who have a condition called molar-incisor hypomineralization (MIH).
- Conditions
- Enamel Hypoplasia, Molar-Incisor Hypomineralization (MIH), Restoration of Permanent Molars Affected by MIH With CAD/CAM Blocks
- Trial name
- NCT06987448
- Testing
- Semi-direct onlay restoration using CAD/CAM hybrid composite block, Semi-direct onlay restoration using CAD/CAM hybrid ceramic block
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Alp Akça
Sensitivity, Tooth
Efficacy of Tooth Bleaching With 35% and 6% Hydrogen Peroxide in Primary Dentition
The aesthetics of dental elements generates great psychological and social impacts, both in the deciduous and permanent dentition. One of the techniques widely used to visually improve the appearance of teeth is bleaching.
- Trial name
- NCT05789004
- Testing
- Tooth Bleaching with Whiteness HP Automixx 35%, Tooth Bleaching with Whiteness HP Automixx 6%
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dentin Sensitivity
Nano-hydroxyapatite With Potassium Nitrate in the Therapy of the Dental Sensitivity
The chief aim of this study is to evaluate the difference in tooth sensitivity after having used a gel containing nano - hydroxyapatite and potassium nitrate This randomized double-blind clinical study is designed to compare the…
- Trial name
- NCT02895321
- Testing
- Cavex Bite&White ExSense, Colgate, Protection Caries
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Università degli Studi di Sassari