Clinical trials: Dependence
Cannabis Use Disorder
CANDIS - Targeted Treatment for Cannabis Disorders
The purpose of this study is to develop a modular treatment program for cannabis use disorders and the evaluation of the effectiveness in a controlled clinical study.
- Trial name
- NCT00252980
- Testing
- Psychotherapy
- Where
- Germany
- Volunteers
- 210 people
- Sponsor
- Technische Universität Dresden
Opioid-use Disorder, Opioid Dependence
Comparing Home, Office, and Telehealth Induction for Medication Assisted Treatment for Opioid Use Disorder
HOMER is a national study comparing three methods of induction for Medication Assisted Treatment (MAT) for Opioid Use Disorder (OUD); home versus office versus telehealth-based inductions.
- Trial name
- HOMER (NCT04664062)
- Testing
- Medication Assisted Treatment
- Where
- 2 sites in United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hydrocephalus in Infants
Cerebrospinal Fluid Proteom in Dependence of Intranasal Breast Milk
Investigation of the cerebrospinal fluid proteom in preterm infants with posthemorrhagic hydrocephalus in our neonatology center with analysis for modulation of proteom in dependence of breastmilk feeding and way of application…
- Trial name
- NAMU (NCT04229693)
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital of Cologne
Smoking Cessation; Tobacco Dependence
Characterization of Smoking Habits Patterns in Medical Doctors of a Central Hospital in Portugal - What Has Changed After 15 Years? A Comparative Cross-sectional Study
Abstract: Tobacco dependence remains one of the primary health care concerns worldwide. Attitude of healthcare professionals towards smoking is crucial for any long-term prevention and smoking cessation program.
- Trial name
- NCT02913989
- Testing
- Smoking habits characterization
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar Lisboa Ocidental
Cannabis, Cannabis Intoxication
Do Adolescents and Adults Differ in Their Acute Response to Cannabis?
The acute effects of cannabis may differ between adolescents and adults. Furthermore, these effects may be tempered by the presence of cannabidiol.
- Conditions
- Cannabis, Cannabis Intoxication, Cannabis Use, Cannabis Dependence
- Trial name
- CannTeenA (NCT04851392)
- Testing
- Cannabis with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), Cannabis with THC without CBD
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University College, London
Tobacco Use Disorder, Tobacco Dependence
The PROMPT Pilot Study
The PROMPT Pilot Study is a feasibility mixed methods prospective cohort study following principles of community-based participatory action research.
- Conditions
- Tobacco Use Disorder, Tobacco Dependence, Tobacco Use Cessation
- Trial name
- NCT03626064
- Testing
- Smoking Cessation Counselling, Nicotine Replacement Therapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Opioid-Related Disorders, Substance-Related Disorders
Evaluation of L-alpha-acetylmethadol (LAAM) in Methadone Patients - 5
The purpose of this study is to determine the pharmacokinetics of L-alpha-acetylmethadol (LAAM) in adults transferred from methadone maintenance treatment for opiate dependence.
- Trial name
- NCT00000356
- Testing
- LAAM
- Where
- United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcohol Dependence, Drug Dependence
LINK: Aftercare Monitoring Project
The prevalence of substance use disorders (SUD) in the VA is rising, making SUD(s) among the most commonly diagnosed disorders in the VA.
- Trial name
- NCT00265512
- Testing
- Telephone Case Monitoring, Continuing Care as Usual
- Where
- 3 sites in United States
- Volunteers
- 667 people
- Sponsor
- VA Office of Research and Development
Nicotine Dependence
Evaluation of Very Low Nicotine Content Cigarettes in Adolescent Smokers
The purpose of this study is to determine how reducing the level of nicotine in cigarettes may affect adolescent smoking behavior.
- Trial name
- NCT02587312
- Testing
- Very low nicotine content cigarettes, Standard nicotine content cigarettes
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Brown University
Opioid Addiction, Opioid Abuse, Continuous Use
Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction
Healthy adult human male facial skin surface lipid liquid pheromone given by mouth to opioid addicts cures them without any withdrawal symptoms whatsoever 250mg on chewing gum vehicle by mouth.
- Conditions
- Opioid Addiction, Opioid Abuse, Continuous Use, Opioid Use, Opioid-Related Disorders
- Trial name
- NCT03394911
- Testing
- 250mg healthy adult male facial skin surface lipid liquid pheromone
- Volunteers
- 500 people
- Sponsor
- Bubba Nicholson
Substance Abuse, Substance Dependence
Adolescent Outpatient and Continuing Care Study
The purpose of this study was to evaluate the effectiveness and cost-effectiveness of two types of outpatient treatment with and without Assertive Continuing Care (ACC) for 320 adolescents with substance use disorders.
- Trial name
- AOCCS (NCT01381133)
- Testing
- Chestnut Bloomington Outpatient (CBOP), Motivational Enhancement Therapy/Cognitive Behavior Treatment (MET/CBT 7), Assertive Continuing Care (ACC)
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Chestnut Health Systems
Vaping
Social Media Intervention to Stop Nicotine and Cannabis Vaping Among Adolescents
Social media based intervention to support teens in their efforts to quit vaping.
- Trial name
- NCT04707911
- Testing
- Social Media Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiovascular Disease, Essential Hypertension
The Northwest Coalition for Primary Care Practice Support
The purpose of this project is to build capacity for quality improvement (QI) in small primary care practices across Washington, Oregon and Idaho by improving risk factors for heart attacks such as blood pressure, cholesterol and…
- Conditions
- Cardiovascular Disease, Essential Hypertension, Nicotine Dependence, Hyperlipidemia
- Trial name
- H2N (NCT02839382)
- Testing
- Coaching, Educational Outreach, Site Visits
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Kaiser Permanente
Alcoholism, Substance Abuse
Recognition and Early Intervention for Alcohol and Substance Abuse in Adolescence in Adolescent
ASSIST mini-intervention is applied in an electric form in adolescent outpatients to see if it
- Conditions
- Alcoholism, Substance Abuse, Alcohol Dependence, Alcohol-Related Disorders
- Trial name
- REAL-SMART (NCT06262958)
- Testing
- ASSIST, Treatment as usual
- Where
- Finland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
School Attendance, Welfare Dependence
Testing the Efficacy of the Ability School Engagement Partnership Program (ASEP)
This project is an up-scaled test of the Ability School Engagement Partnership (ASEP) Project. The ASEP is a partnership program that aims to increase school attendance and is grounded in the theory of Third-Party-Policing (TPP).
- Conditions
- School Attendance, Welfare Dependence, Antisocial Behavior
- Trial name
- ASEP (NCT04281966)
- Testing
- Ability School Engagement Program Conference
- Where
- Australia
- Volunteers
- 753 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Quality of Life, Burden, Dependency
Impact of the Use of a Closed-loop Insulin Therapy on the Burden of the Diabetes and the Quality of Life
The use by diabetes patients of real-time Continuous Glucose Monitoring (CGM) system is becoming widespread and has changed diabetic practice. Automated closed-loop (CL) insulin therapy has come of age.
- Trial name
- IMPLIQUE (NCT04939766)
- Testing
- Activation of a closed loop device in an insulin pump device with GCM
- Volunteers
- 250 people
- Sponsor
- VitalAire
Substance Dependency, Addiction
Working Memory Training for Substance Dependent Individuals
Background: Substance abusers show impaired working memory (WM) functioning. Promising findings show training WM results in an improved working memory capacity (WMC) and a decrease of clinical symptoms in a range of disorders…
- Conditions
- Substance Dependency, Addiction, Anxiety, Depression
- Trial name
- NCT02119949
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Erasmus Medical Center
Heroin Dependence, Morphine Dependence
Buprenorphine/Naloxone Versus Clonidine for Inpatient Opiate Detoxification - 1
The purpose of this study is to assess buprenorphine/naloxone versus clonidine for inpatient opiate detoxification.
- Conditions
- Heroin Dependence, Morphine Dependence, Substance Withdrawal Syndrome
- Trial name
- NCT00032955
- Testing
- Buprenorphine/naloxone
- Where
- 6 sites in United States
- Volunteers
- 163 people
- Sponsor
- University of California, Los Angeles
Chronic Respiratory Failure, Tracheostomy Complication
Parental Perception of COVID-19 Vaccine in Technology Dependent Patients
This study involves conducting a telephonic or in person survey regarding parental perception and attitudes about vaccinating the respective "technology dependent" child with the COVID 19 vaccination.
- Conditions
- Chronic Respiratory Failure, Tracheostomy Complication, Mechanical Ventilation Complication
- Trial name
- NCT05084976
- Testing
- COVID 19 vaccine counseling
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwell Health
Lung Disease
The Effectiveness of BreatheMAX Breathing Device on Secretion Clearance
The purpose of this study is to determined effects of BreatheMAX on secretion clearance.
- Trial name
- ESMOSC (NCT01090804)
- Testing
- BreatheMAX breathing device
- Where
- Thailand
- Volunteers
- 14 people
- Sponsor
- Khon Kaen University