Clinical trials: Depression
Mood, Depression Disorders
Technology Exposure and Child Health: Wellness Impact and Social Effects: An Observational Product Registry Study
The goal of this study is to understand how children's mobile device usage (smartphones or tablets), including social media use and online games, are related to their mental wellness and mental health, as well as some aspects of…
- Conditions
- Mood, Depression Disorders, Anxiety Disorders, Sleep
- Trial name
- TECHWISE (NCT06664944)
- Where
- United States
- Volunteers
- 912 people, healthy volunteers welcome
- Sponsor
- Aura
Bipolar Disorder, Bipolar Depression
Uridine Adolescent Bipolar Depression Randomized Controlled Trial
This is a randomized, double-blind, placebo-controlled study of the investigational drug uridine as a treatment for depressed adolescents with bipolar disorder (i.e. "bipolar depression").
- Conditions
- Bipolar Disorder, Bipolar Depression, Manic Depression
- Trial name
- NCT01805440
- Testing
- Uridine
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Utah
Depression, Anxiety
Mental Health E-screening in Pregnant and Postpartum Women
To compare e-screening versus usual screening on: 1) women's and healthcare providers' views on feasibility and acceptability; 2) rates of detection of prenatal and postpartum depression and anxiety; 3) perceived risk and benefit…
- Trial name
- NCT01899534
- Testing
- E-screening
- Where
- 3 sites in Canada
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Depression, Mental Health Issue
Economic Evaluation of the MEWE Intervention
Cash transfers have shown promise in preventing intimate partner violence, and in reducing recipients' stress levels. Cash transfers with behavioral or psychological interventions have shown limited effectiveness at reducing…
- Conditions
- Depression, Mental Health Issue, Intimate Partner Violence, Domestic Violence
- Trial name
- MEWE-EE (NCT05598697)
- Testing
- Life Skills Building (LSB) curriculum for males, Life Skills Building (LSB) curriculum for females, Cash transfer to adult females
- Where
- Pakistan
- Volunteers
- 1,536 people, healthy volunteers welcome
- Sponsor
- London School of Economics and Political Science
Depression, Depression, Bipolar
Dallas 2K: A Natural History Study of Depression
The primary objective of this initiative is to implement a prospective study that will allow us to identify and validate biosignatures of response to treatments for depression and depression outcome (using an integrated array of…
- Trial name
- D2K (NCT02919280)
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Neonatal Death, Perinatal Death
Leveraging Interactive Text Messaging to Monitor and Support Maternal Health in Kenya
Mobile health (mHealth) interventions such as interactive short message service (SMS) text messaging with healthcare workers (HCWs) have been proposed as efficient, accessible additions to traditional health care in…
- Conditions
- Neonatal Death, Perinatal Death, Depression
- Trial name
- AI-NEO (NCT05369806)
- Testing
- Interactive two-way SMS dialogue
- Where
- 2 sites in Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Mental Health, Physical Activity
Classroom Exercise Frequency and Mental Health in Medical Students
This 16-week, three-group, nonrandomized interventional study evaluated whether the weekly frequency of a brief classroom-based physical exercise program was associated with changes in mental health and physical activity among…
- Trial name
- NCT07756879
- Testing
- Brief Classroom-Based Physical Exercise Program
- Where
- Colombia
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dynamical Business and Science Society - DBSS International SAS
Bipolar Disorder, Major Depressive Disorder
The Gut Microbiota of Bipolar and Depression
Background: The gut microbiome is emerging as an important factor in regulating mental health yet it remains unclear what the target should be for psychiatric treatment.
- Trial name
- NCT03062332
- Testing
- Faecal genome
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Post Partum Depression
Effect of a Cooperative Education Program Based on Precede-Proceed Model During Pregnancy on Postpartum Depression
This trail aims to evaluate the effects of a cooperative education program based on precede-proceed model during pregnancy on preventing postpartum depression in southern Razavi Khorasan Province.
- Trial name
- NCT04129476
- Testing
- Cooperative Education Program based on Precede-Proceed Model
- Where
- Iran
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Gonabad University of Medical Sciences
Major Depressive Disorder
Neural Correlates of Stress and Perceived Control in Adolescent Depression
Lack of perceived control, particularly during stress, has been critically implicated in major depressive disorder (MDD) and anhedonic symptoms, especially among female adolescents; yet the neural underpinnings of perceived…
- Trial name
- NCT04788524
- Testing
- Computer Task Manipulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Major Depressive Disorder
Neural Components Underlying the Treatment of Adolescent Depression
The goal of the study is to examine how cognitive behavioral therapy (CBT), a common treatment for adolescent depression, affects brain functioning.
- Trial name
- NCT01717508
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Depression Disorders, Suicidality
Effectiveness of the Adapt for Life, Mental Wellness and Suicide Prevention Program
Adapt for Life is a mental health and wellbeing program designed to help young people develop healthy behaviors and important life skills to manage stress and mental health challenges.
- Trial name
- AFL (NCT06979479)
- Testing
- school-based intervention
- Where
- United States
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Anxiety, Depression - Major Depressive Disorder
Profiling Vulnerability and Resilience for Mental Illness Following Viral Infections: Translating Epidemiology to Deep-phenotyping.
The study protocol was submitted to ERA-NET NEURON for funding on 28/06/2023. Description of the Israeli responsibilities was extracted from the full submitted research protocol. The protocol includes two studies (CHS1 and CHS2).
- Conditions
- Anxiety, Depression - Major Depressive Disorder, Bipolar, Schizophenia Disorder
- Trial name
- Viral-MI (NCT07453420)
- Where
- Israel
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Depression
Major Depression and Inflammatory Risk Markers for Coronary Heart Disease
The overall purpose of this research is to examine whether depression influences immune system function. Studies indicate that individuals who are depressed experience coronary heart disease at a higher rate than expected.
- Trial name
- NCT00037505
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Mental Depression
Using Group Interpersonal Psychotherapy to Improve the Well-Being of Adolescent Girls
Adolescent girls in developing countries face high rates of adversity and are at an elevated risk of depression and other forms of psychological distress.
- Trial name
- NCT03966833
- Testing
- IPT-G, Unconditional Cash Transfer
- Where
- Uganda
- Volunteers
- 1,914 people, healthy volunteers welcome
- Sponsor
- George Washington University
Prenatal Anxiety, Depression
Prenatal Listening to Songs Composed for Pregnancy and Symptoms of Anxiety and Depression: a Pilot Study
Prenatal anxiety and depression are distressing for the expectant mother and can have adverse effects on her fetus and child. This study aimed to determine whether listening to specially composed songs would be an effective…
- Trial name
- NCT02776293
- Testing
- Relaxation, Music
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Goldsmiths, University of London
Depression
Childhood Adversity, Genetic Polymorphisms and Stress in First Onset Major Depression
The Blue Sky Project, a 5-year study funded by the Canadian Institutes of Health Research, seeks to examine how genetics and early life experiences work together to cause a person's very first onset of depression by increasing…
- Trial name
- NCT00517764
- Testing
- escitalopram
- Where
- 2 sites in Canada
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Bipolar Disorder
Oral Uridine for Treatment of Bipolar Depression in Adolescents
The purpose of the study is to see if the investigational medication uridine reduces depression symptoms in adolescents with bipolar disorder. Uridine is a naturally occurring chemical that is made by the human liver.
- Trial name
- NCT00841269
- Testing
- Uridine
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Utah
Trauma, Anxiety
Testing the Effects of Project Calm in Ukrainian Schools
The purpose of this study is to test the effectiveness of a universal, digital, single-session intervention for youth mental health, functioning, and well-being, when implemented with Ukrainian children and adolescents.
- Conditions
- Trauma, Anxiety, Depression, Child Behavior
- Trial name
- NCT06217705
- Testing
- Project Calm
- Where
- United States
- Volunteers
- 728 people, healthy volunteers welcome
- Sponsor
- Harvard University
Tracheotomised Children, Anxiety of Parents
Parental Mental Health After Tracheostomy in Early Childhood
To assess the prevalence of anxiety / depression in post- hospital for parents (mothers and fathers) of children with tracheotomy before the age of 1 year between 2000 and 2012.
- Conditions
- Tracheotomised Children, Anxiety of Parents, Depression of Parents
- Trial name
- TRACH (NCT02884570)
- Testing
- Auto-Questionnaires
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier