Clinical trials: Depression Anxiety Disorder
Substance Use, Conduct Disorder
Early Family-Centered Prevention of Drug Use Risk (Aka Early Steps)
The investigators are testing the efficacy of a family-based preventive intervention, which began when the children were age 2, with children at risk for developing significant conduct problems.
- Conditions
- Substance Use, Conduct Disorder, Depression, Anxiety
- Trial name
- Early Steps (NCT01098695)
- Testing
- Ecological Family Intervention and Treatment (EcoFIT)
- Where
- 3 sites in United States
- Volunteers
- 731 people
- Sponsor
- University of Oregon
Pulmonary Resection
Impact of Pulmonary Rehabilitation After Lung Resection for Cancer on Patients' Level of Anxiety and Depression
The interest of pulmonary rehabilitation for patients who underwent lung resection for cancer remains controversial. The investigators studied the effects of the RR and its impact on quality of life and level of anxiety and…
- Trial name
- NCT04985474
- Testing
- questionnaires
- Volunteers
- 133 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Autism Spectrum Disorder, Depression - Major Depressive Disorder
Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models
This study investigates whether AI-driven analysis of speech can accurately predict clinical diagnoses and assess risk for various mental or behavioral health conditions, including attention-deficit/hyperactivity disorder (ADHD)…
- Conditions
- Autism Spectrum Disorder, Depression - Major Depressive Disorder, Anxiety, Generalized, Bipolar Disorder (BD)
- Trial name
- MINDAIM (NCT06792175)
- Testing
- Solicue Machine Learning Models, Mercuria Machine Learning Models
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Psyrin Inc.
Educational Activities
The Effect Of Education Given According to Meleıs' Transitional Theory to Patients With Pacemaker
This study will be carried out to determine the effect of training given according to Meleis's Transition Theory to patients with pacemaker implantation on anxiety, depression and self-efficacy levels.
- Trial name
- NCT06204601
- Testing
- Education According to Meleis' Transitional Theory to Patients With Pacemaker
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ordu University
Anxiety, Depression
Using Neuroimaging to Understand Children's Mental Health and Treatment Outcomes
The study will compare the impact of Child STEPs versus usual school-based therapy on neural and companion behavioral measures of self-regulation.
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT03112265
- Testing
- Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems, Monitoring and Feedback System, Treatment as usual
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Harvard University
Depression, Anxiety
Caregiver Burden and Distress in Hematopoeitic Stem Cell Transplant
The purpose of this study is to examine the impact that serving as a caregiver for a patient undergoing hematopoietic stem cell transplant has on the caregiver.
- Conditions
- Depression, Anxiety, Fatigue, Distress
- Trial name
- NCT01084694
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northside Hospital, Inc.
Anxiety Disorders and Symptoms, Depressive Symptoms
Selective Prevention Transdiagnostic Intervention for At-risk Adolescents
Emotional disorders (anxiety and/or depression) are severely undiagnosed and untreated despite being among the most common mental disorders, particularly at a young age.
- Trial name
- PROCARE (NCT04851366)
- Testing
- PROCARE+ (with add-on modules), PROCARE (UP-A for selective purposes), Active control condition
- Where
- 3 sites in Spain
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Emotional Regulation, Virtual Reality
E-Emotio Project A Gamified Preventive School-based Paradigm Using Virtual Reality Technologies for Improving Emotional Regulation in Children and Adolescents.
Introduction and Significance: Preventive interventions have been shown to reduce the risk of developing anxiety and depression, making them a critical focus area in mental health promotion for children and adolescents.
- Conditions
- Emotional Regulation, Virtual Reality, Anxiety, Depression
- Trial name
- e-Emotio (NCT06236919)
- Testing
- VR cognitive training, VR nature exposure relaxation
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Anxiety, Depression / Major Depressive Disorder
The Effectiveness of a One-stop Electronic Clinic for Psychological Service (eClinic) in Hong Kong
With an increasing need for effective and accessible mental health services, telepsychology can be one promising solution to narrowing the gap between demand and supply.
- Conditions
- Anxiety, Depression / Major Depressive Disorder, Common Mental Disorder
- Trial name
- NCT07597967
- Testing
- Internet-based Unified Protocol (UP) Intervention
- Where
- Hong Kong
- Volunteers
- 420 people
- Sponsor
- New Life Psychiatric Rehabilitation Association
Anxiety, Depression
Evaluation of Different Psychiatric Symptoms in Patients With Thyroid Dysfunction
1. Evaluate psychiatric symptoms in patients with thyroid dysfunction. 2. Investigate effect of treatment on psychiatric symptoms after 2 months.
- Conditions
- Anxiety, Depression, Thyroid Dysfunction
- Trial name
- NCT06185309
- Volunteers
- 85 people
- Sponsor
- Assiut University
Multimorbidity, Comorbidity
A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students
Junior high school students are in a critical period of physical and mental development, currently facing two major health challenges: first, persistently high rates of myopia with a noticeable trend toward younger onset; second…
- Conditions
- Multimorbidity, Comorbidity, Common Diseases in Children and Adolescents, Myopia
- Trial name
- NCT07237698
- Testing
- The intervention group participated in specialized physical education courses.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Wu
Obstructive Sleep Apnea-Hypopnea Syndrome, Anxiety Disorders
EGR2 and NLRP3 Pathways in Obstructive Sleep Apnea-Related Cognitive and Mood Disorders
Obstructive sleep apnea-hypopnea syndrome (OSAS) is a common disorder in which repeated airway blockages during sleep lead to low oxygen levels, inflammation, and disrupted sleep.
- Conditions
- Obstructive Sleep Apnea-Hypopnea Syndrome, Anxiety Disorders, Depressive Disorders
- Trial name
- NCT07120711
- Testing
- EGR2/NLRP3 pathway activity, fatty tissue
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Concussion, Brain, TBI
Collaborative Care Model for the Treatment of Persistent Symptoms After Concussion Among Youth
SPECIFIC AIMS While post-concussive symptoms following sports-related concussion are typically transient and resolve spontaneously within two weeks of concussive injury, 14% or more of youth who sustain concussion experience…
- Conditions
- Concussion, Brain, TBI, Depression, Anxiety
- Trial name
- NCT03034720
- Testing
- Collaborative Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Seattle Children's Hospital
Anxiety, Depression
Examining the Effects of an Improvisation Group
This study is taking place to examine the preliminary effects of improvisational therapy (improv group) on social anxiety for youth at the Youth Wellness Centre (YWC). The improv group will run for 12-weeks as a drop-in group.
- Conditions
- Anxiety, Depression, Self Concept Alteration, Social Support
- Trial name
- NCT03147924
- Testing
- Improvisation Group
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
HIV Infections, Pregnancy Related
Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe
The purpose of this study is to develop a multi-level PrEP adherence and persistence intervention as an adaptation of the TENDAI ('grateful' in Shona) program, a problem-solving approach to reduce depression and increase HIV…
- Conditions
- HIV Infections, Pregnancy Related, Depression, Anxiety
- Trial name
- TENDAI4PrEP (NCT06226155)
- Testing
- TENDAI4PrEP, Enhanced treatment as usual
- Where
- Zimbabwe
- Volunteers
- 165 people
- Sponsor
- Massachusetts General Hospital
Depression, Anxiety
Behavioral Telehealth in Low-resource Primary Care Settings for Anxiety and Depression in Youth
The goal of this clinical trial is to test a brief, behavioral telehealth treatment program (STEP-UP) for depression and anxiety in youths (age 8-16 years old).
- Trial name
- STEP-UP (NCT06273982)
- Testing
- STEP-UP (transdiagnostic behavioral therapy for pediatric anxiety and depression), ARC (assisted referral to community care)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- San Diego State University
Posttraumatic Stress Disorder, Depression
Controlled Trial of Early Intervention With Children and Adolescents Exposed to Nonrelational Traumatic Events
Background: International studies have shown that a substantial number of children and adolescents are exposed to potentially traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT02299583
- Testing
- Preventive intervention trauma-informed early intervention
- Where
- Denmark
- Volunteers
- 684 people
- Sponsor
- Carolina Magdalene Maier
Depression and Suicide Ideation, Anxiety
Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence
This pilot study examines the feasibility and acceptability of a culturally adapted psychological intervention-Problem Management Plus with Emotional Processing (PM+ EP)-for young Afghans aged 16-30 experiencing high…
- Conditions
- Depression and Suicide Ideation, Anxiety, PTSD
- Trial name
- NCT06980441
- Testing
- Problem Management Plus with Emotional Processing module
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Peace of Mind Association (PoMA)
Depression
Examination of a Soy-Based Supplement for Major Depression
The purpose of this study is to find out if the soy-based dietary supplement Novasoy (Registered Trademark) is effective for the short-term treatment of clinical depression.
- Trial name
- NCT00042380
- Testing
- Novasoy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Mental Health (NIMH)
Traumatic Brain Injury, Depression
A Trial of Two On-Line Interventions for Child Brain Injury
The primary aims of this project are to examine the feasibility and relative efficacy of two models of on-line intervention for families of children with traumatic brain injury: one, a model emphasizing cognitive appraisals and…
- Conditions
- Traumatic Brain Injury, Depression, Anxiety Disorders
- Trial name
- NCT00178022
- Testing
- Case management and problem solving therapy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh