Clinical trials: Depression Disorders
LGBTQ, Racial Disparities
Lakota Family Acceptance Project
The goal of this open pilot trial (OPT) is to develop a Lakota-adapted Family Acceptance Project (LFAP) for Indigenous 2SLGBTQ+ youth and their caregivers.
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP OPT (NCT07326748)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Inflammatory Bowel Diseases, Mental Health Issue
IBDminds - Mapping the Influence of aNxiety and DepreSsion on IBD
People with Inflammatory bowel disease (IBD) can get challenging symptoms. Things like diarrhoea, tummy pain and being tired all the time are common. People often get IBD in their teens or twenties.
- Trial name
- IBDminds (NCT07175454)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 450 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Postpartum Depression
Mobile Phone Based Peer Support to Prevent Postpartum Depression Among Adolescent Mothers
This pilot study will evaluate the feasibility and acceptability of a mobile phone based peer support intervention among adolescent mothers.
- Trial name
- NCT02818075
- Testing
- Mobile Phone Based Peer Support, Usual Care
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Depression
Benefits of Switching Antidepressants Following Early Nonresponse
Introduction and Purpose: Most of the guidelines for the treatment of major depression recommend the use of antidepressants for 4 to 8 weeks.
- Trial name
- NCT00519012
- Testing
- Sertraline to Paroxetine, Paroxetine to Sertraline
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Oizumi Hospital
Anxiety Disorders, Depressive Disorder, Major
Auricular Acupuncture vs. Progressive Muscle Relaxation in Patients With Anxiety Disorders or Major Depressive Disorder.
The purpose of this study is to determine whether auricular acupuncture (AA) according to the NADA protocol and progressive muscle relaxation (PMR) differ in their effectiveness of treating people with anxiety disorders or major…
- Trial name
- NCT02340351
- Testing
- Auricular acupuncture, Progressive muscle relaxation
- Volunteers
- 136 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Panic Disorder, Panic Disorder With Agoraphobia
Construction of a Questionnaire on Panic Disorder and Agoraphobia
For the first time panic disorder and agoraphobia are included as separate disorders in the DSM-5. Thus, agoraphobia no longer represents a subcategory of panic disorder.
- Conditions
- Panic Disorder, Panic Disorder With Agoraphobia, Agoraphobia, Agoraphobia With Panic Attacks
- Trial name
- NCT03885453
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Ulrike Willutzki
Stress Disorders, Post-Traumatic, Depression
Psychological and Psychosocial Intervention With War-Affected Children
The investigators are interested in knowing whether a group-based, trauma-focused intervention (Trauma Focused Cognitive Behavioral Therapy) is superior to a more general, non trauma-focused, psychosocial intervention (Child…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Anxiety, Conduct
- Trial name
- NCT01509872
- Testing
- Trauma Focused Cognitive Behavioral Therapy, Child Friendly Space
- Where
- Republic of the Congo
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Bipolar Disorder, Depression
Pediatric Bipolar Registry
The goal of the Pediatric Bipolar Registry (PBR) is to provide a comprehensive assessment regarding the diagnosis and treatment of pediatric bipolar disorder to children and adolescents with any current mood state and/or…
- Conditions
- Bipolar Disorder, Depression, Mania, Psychosis
- Trial name
- PBR (NCT02360267)
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- The University of Texas Health Science Center, Houston
Depression
N-acetylcysteine in the Treatment of Depressive Symptoms in Bipolar Offspring
N-acetylcysteine in the treatment of depressive symptoms in youth at high-risk for bipolar disorder: a functional connectivity study
- Trial name
- NCT02865629
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Cincinnati
Anxiety, Depression
Child STEPS for Youth Mental Health in Maine Sustainability
The overarching goal of this project is to study the sustainability of MATCH-ADTC within community mental health clinics, to learn what is needed for evidence-based practices (EBPs) to take root and thrive within a public system.
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT03112304
- Testing
- MATCH-ADTC, TRAC
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Harvard University
Depression, Anxiety
Effect of Music Therapy in Medical Students (EMTMS)
Mental health has become an increasingly pressing concern, especially since the onset of the COVID-19 pandemic. However, not all individuals experiencing mental suboptimal states require pharmacological treatment.
- Conditions
- Depression, Anxiety, Insomnia
- Trial name
- NCT05949736
- Testing
- The Online intervention platform
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Jiangsu Province Nanjing Brain Hospital
Cardiovascular Diseases, Heart Diseases
University of North Carolina Alumni Heart Study
To continue surveillance of the participants in the University of North Carolina Alumni Heart Study, which tests the hypothesis that hostility and related psychosocial factors are involved in the pathogenesis of coronary heart…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Depression
- Trial name
- NCT00005398
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 6,340 people
- Sponsor
- Duke University
Inflammatory Bowel Disease (IBD), Ulcerative Colitis
Healthy Approach to Physical and Psychological Problems in Youngsters With IBD (HAPPY-IBD).
The presented study aims to reduce symptoms of depression and anxiety in adolescents with inflammatory bowel disease and increased symptoms of anxiety and depression by using the disease specific CBT program (PASCET-PI)in order…
- Conditions
- Inflammatory Bowel Disease (IBD), Ulcerative Colitis, Crohn's Disease, Anxiety
- Trial name
- HAPPY-IBD (NCT02265588)
- Testing
- Cognitive behavioral therapy
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Erasmus Medical Center
Chemotherapy Effect
Effect of Nurse-led Education on Parent's Anxiety and Depression on Managing Side Effects of Chemotherapy
ABSTRACT Background: Today, a wide range of pediatric cancers is treated by chemotherapy. More than 21 side effects of chemotherapy have been identified. Among those nausea; vomiting, infection and anemia are most common.
- Trial name
- NCT03753542
- Testing
- Multimedia education, booklet Providence and tele-nursing follow-up
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nomi Waqas Gul
Mental Disorders, Severe
Measuring Development of Brain Responses to Vocal Sounds in Babies of Mums With Mental Illness
CAPRI-Voc examines the differences in how speech and environmental sounds are processed in the infant brain as they grow from 9 to 12 months.
- Trial name
- CAPRI-Voc (NCT04350294)
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Bipolar Disorder, Depressive Disorder
Acute Effectiveness of Additional Drugs to the Standard Treatment of Depression
This study will compare the effectiveness of relatively new antidepressants which have different mechanisms of action. Buproprion (Wellbutrin) works on dopamine and the dopaminergic pathway.
- Trial name
- NCT00001483
- Testing
- buproprion (Wellbutrin), sertraline (Zoloft), venlafaxine (Effexor)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Mental Health (NIMH)
Parent Child Abuse, Domestic Violence
Parenting for Lifelong Health - Thailand
Pilot design: The feasibility pilot of PLH for Young Children in Thailand has a single-site, pre-post design with no control group, with the aims of assessing programme implementation, cultural and contextual relevance, and study…
- Conditions
- Parent Child Abuse, Domestic Violence, Child Behavior Problem, Child Neglect
- Trial name
- NCT03539341
- Testing
- PLH-Thailand parenting programme, Control (care as usual)
- Where
- 4 sites in Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Major Depressive Disorder, Depression
Treatment for Adolescents With Depression Study (TADS)
TADS is designed to compare the effectiveness of established treatments for teenagers suffering from major depressive disorder (MDD).
- Trial name
- NCT00006286
- Testing
- Fluoxetine, Psychotherapy
- Where
- 12 sites in United States
- Volunteers
- 432 people
- Sponsor
- National Institute of Mental Health (NIMH)
Postpartum Depression, Intimate Partner Violence
Case Management Study for Postpartum Depression and Intimate Partner Violence
The objective of the study was to assess the prevalence, timing, and co-occurrence of positive screens for maternal postpartum depression (PPD) and intimate partner violence (IPV) for women bringing their young infants for…
- Trial name
- NCT00560027
- Testing
- Case Management by Family Support Counselor (not RCT)
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
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