Clinical trials: Depression Disorders
Postpartum Depression, Quality of Life
Whether Probiotics Use in Neonate and Infant Improve Their Mother's Life Quality
Postpartum depression and poor quality of life during postpartum were an vital issue in recent years. Infant's health condition was thought to be a possible reasons related mother's postpartum quality of life, and functional…
- Conditions
- Postpartum Depression, Quality of Life, Functional Gastrointestinal Disorders, Probiotics
- Trial name
- NCT04741971
- Testing
- Probiotics group, Non-probiotics group
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Anxiety, Depression
Mental Health INtervention With Digital APPlications (MIND-APP): Evaluating the Effectiveness of the Tankevirus and Grubl Mental Health Apps
The MIND-APP trial is a 3-arm randomized controlled trial (1:1:1 allocation) conducted fully remotely via a bespoke smartphone research platform.
- Trial name
- MIND-APP (NCT07627204)
- Testing
- Tankevirus, Grubl
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Akershus
Depression, Anxiety
Description of the Lived Experiences of Family Caregivers for People With Mental Health Comorbidities
Mental health problems such as depression, trauma and anxiety are common in low-resource contexts, such as Zambia. Comorbidity, or having multiple mental health problems, is the norm.
- Conditions
- Depression, Anxiety, Trauma
- Trial name
- MCE (NCT07760701)
- Where
- Zambia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Depressive Disorder
Augmentation of Interpersonal Psychotherapy With High-Definition Transcranial Direct Current Stimulation for Adolescent Depression
Depression is among the most prevalent psychiatric disorders, with an upward trend in its manifestation in younger individuals. In contrast to adult depression, adolescent depression often presents with longer attack durations…
- Trial name
- NCT06061653
- Testing
- IPT plus HD-tDCS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Depression, Anxiety
Internet-Delivered Cognitive Behaviour Therapy for Adolescent Depression
The purpose of this study is to determine whether tailored internet-administrated cognitive behaviour therapy (CBT) is a feasible approach in the treatment of depressive symptoms and comorbid anxiety symptoms.
- Trial name
- NCT02363205
- Testing
- Tailored Internet-administrated CBT-Treatment
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Linkoeping University
Depressive Symptoms
Ecological Momentary Intervention for Depressive Symptoms in a Community Sample in Hong Kong
The key aim of the study is to test the efficacy of a 4-week ecological momentary intervention (EMI), as compared with the regular weekly-based intervention (control group), in reducing (1) symptoms of depression and (2)…
- Trial name
- NCT04985422
- Testing
- Smartphone-based Daily Ecological Momentary Intervention, Smartphone-based Weekly-delivered Information
- Where
- Hong Kong
- Volunteers
- 262 people
- Sponsor
- The University of Hong Kong
Depression, Anxiety
Caregiver Burden and Distress in Hematopoeitic Stem Cell Transplant
The purpose of this study is to examine the impact that serving as a caregiver for a patient undergoing hematopoietic stem cell transplant has on the caregiver.
- Conditions
- Depression, Anxiety, Fatigue, Distress
- Trial name
- NCT01084694
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northside Hospital, Inc.
Adjunct in the Treatment of Depressive Disorder
A Randomized, 52-Week Extension Study to Evaluate the Maintenance of Remission, Relapse Prevention, and Long-Term Safety of CreNeuroS™ in Patients With Major Depressive Disorder Who Achieved Remission Following an 8-Week Parent Study
This multicenter, randomized, open-label extension study will evaluate the maintenance of remission, relapse prevention, long-term clinical outcomes, and safety of CreNeuroS™ in participants with Major Depressive Disorder (MDD)…
- Trial name
- NCT07893002
- Testing
- No intervention, CreNeuroS™ CNS Fish Oil Plus Softgels, 1 capsule orally once daily, CreNeuroS™ CNS Fish Oil Plus Softgels, 2 capsule orally once daily
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Sichuan Credit Pharmaceutical Co., Ltd.
Lactation Suppressed, Cabergoline Adverse Reaction
Factors and Outcomes Associated With Postpartum Cabergoline Use
Cabergoline is frequently being requested by many postpartum women with a live newborn to suppress lactation. The aim of the study is to investigate which women desire such an intervention, and what side effects they are…
- Conditions
- Lactation Suppressed, Cabergoline Adverse Reaction, Postpartum DVT, Postpartum Depression
- Trial name
- NCT03965572
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Laniado Hospital
Asthma, Major Depressive Disorder
Treating Caregiver Depression to Improve Childhood Asthma: Impact and Mediators
The investigators propose a one-year, repeated measures, within-subject design to examine the impact of improved caregiver depression on child asthma outcomes.
- Trial name
- NCT02809677
- Testing
- Non-Interventional
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- University of Texas Southwestern Medical Center
Stress, Anxiety
Impact of Teaching "Meditation Techniques" on the Mental Health and Quality of Life of Medical Students
Studies show a high number of medical students suffering from mental health problems. Although there are several studies investigating how these problems could impact students' life and performance, few studies have investigated…
- Conditions
- Stress, Anxiety, Depression, Quality of Life
- Trial name
- NCT03132597
- Testing
- Mindfulness training
- Where
- Brazil
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Federal University of Juiz de Fora
Depression, Anxiety
Game-Based Digital Intervention for Depression in Adolescents
The goal of this clinical trial is to evaluate the effectiveness of digital interventions in treating depression and anxiety in adolescents.
- Trial name
- NCT06778785
- Testing
- Digital Intervention, Health Education, Personalization Algorithm
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Anorexia Nervosa
Microbiome Shifts in Adolescent Anorexia Nervosa
The aim of this study is to evaluate the effect of starvation and recovery in adolescent anorexia nervosa patients in regard to microbiome activity and composition and to elucidate potential connections between weight gain…
- Trial name
- MaAN (NCT02962726)
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Neurofibromatosis
Acceptance and Commitment Therapy for Adolescents and Young Adults With Neurofibromatosis and Chronic Pain
Background: Neurofibromatosis type 1 (NF1) is a genetic disorder that can cause frequent and significant pain. This pain can have a severe impact on a person s quality of life.
- Trial name
- NCT01633008
- Testing
- ACT Workshop
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
SKOLKONTAKT - Social Skills Training in a School Setting
The study investigates the behavioral effects of an adapted manual-based social skills training program (SKOLKONTAKT) for the mainstream education plan delivered by school personnel, with pupils (15-20 years) with…
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Anxiety, Depression
- Trial name
- SKOLKONTAKT (NCT04302818)
- Testing
- SKOLKONTAKT, Social activity group
- Where
- Sweden
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Major Depressive Disorder
Mental Health Telemetry for Self-Management in Major Depression
Mood journaling is a cornerstone of self-management in major depressive disorder (MDD). Research over the last decade has shown that electronic mood journals are superior to paper ones.
- Trial name
- MHTV (NCT01999010)
- Testing
- MHT
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- Sunnybrook Health Sciences Centre
Major Depression
Computerized Information-Processing Bias Retraining in Depressed Adolescents
This study will examine how well a novel four-session computerized program, designed to help adolescents learn to interpret ambiguous situations less negatively, reduces symptoms of depression and decreases negative…
- Trial name
- NCT01147913
- Testing
- Computerized Information-Processing Bias Retraining, Attention Control Training
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Massachusetts General Hospital
Treatment-resistant Depression, Major Depressive Disorder
Low-dose Ketamine Infusion Among Adolescents With Treatment-resistant Depression
In the past decades, the prevalence of adolescent depression and suicide increased significantly in Taiwan and worldwide. To date, the suicide mortality is the second mortality cause in the adolescent and young adult population…
- Trial name
- NCT05045378
- Testing
- Ketamine
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Major Depressive Disorder, Major Depressive Disorder, Recurrent
Accelerated Intermittent Theta-Burst Stimulation Ameliorate Major Depressive Disorder by Regulating CAMKII Pathway
Major depressive disorder(MDD) is a complex and heterogeneous mental disorder. Repeated transcranial magnetic stimulation (rTMS), as a non-invasive neuroregulatory technique, has shown a promising function in the treatment of…
- Trial name
- NCT05913960
- Testing
- accelerated intermittent theta burst stimulation, high frequency stimulation
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Major Depressive Disorder
Neural Correlates of Stress and Perceived Control in Adolescent Depression
Lack of perceived control, particularly during stress, has been critically implicated in major depressive disorder (MDD) and anhedonic symptoms, especially among female adolescents; yet the neural underpinnings of perceived…
- Trial name
- NCT04788524
- Testing
- Computer Task Manipulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
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