Clinical trials: Depression Symptoms
Covid19, Mental Health
Mental Health Among Patients, Providers, and Staff During the COVID-19 Era
The Mental Health Among Patients, Providers, and Staff (MHAPPS) Study is designed to study how the COVID-19 pandemic has affected mental health and wellbeing, and how to support mental health while minimizing the burden on the…
- Trial name
- MHAPPS (NCT04700137)
- Testing
- Caring Contacts Plus Introductory Phone Call (CC+), Caring Contacts without an introductory phone call (CC)
- Where
- United States
- Volunteers
- 666 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Addiction, Depression/Anxiety
Healing Lodge First Face Training Evaluation Study
The purpose of this study is to evaluate a culturally grounded training program, xaʔtus (meaning First Face) for Mental Health. This program will train community members in how to recognize and respond to youth and adults…
- Conditions
- Addiction, Depression/Anxiety, Trauma, Psychological, Self-harm
- Trial name
- NCT06290180
- Testing
- First Face for Mental Heatlh
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Post-Traumatic Stress Disorder (PTSD), Depressive Symptoms
Trauma-Focused Cognitive Behavioral Therapy in Unaccompanied Refugee Minors With PTSD in Greece: An RCT
This single-blinded, multicentered, randomized controlled trial aims to evaluate the effectiveness of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) compared to Treatment-as-Usual (TAU) in reducing post-traumatic stress…
- Conditions
- Post-Traumatic Stress Disorder (PTSD), Depressive Symptoms, Anxiety Symptoms, Somatic Symptoms
- Trial name
- TF-CBT (NCT06975280)
- Testing
- Trauma - Focused Cognitive Behavioral Therapy, Treatment as Usual (TAU)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Theodora Anastasiou
Depression, Anxiety
Caregiver Burden and Distress in Hematopoeitic Stem Cell Transplant
The purpose of this study is to examine the impact that serving as a caregiver for a patient undergoing hematopoietic stem cell transplant has on the caregiver.
- Conditions
- Depression, Anxiety, Fatigue, Distress
- Trial name
- NCT01084694
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northside Hospital, Inc.
Osteopathic Manipulative Treatment
Osteopathic Sympathetic Harmonization and Depression
Depression appears to be resistant to the available pharmacological treatments. Autonomic responses accompanied by any psychological stress are sympathetic nervous system (SNS) and neuroendocrine responses are formed by…
- Trial name
- NCT04840043
- Testing
- Osteopathic sympathic harmonization
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Cumhuriyet University
Mental Health Disorder
Dissemination Strategies and Implementation Outcomes of Adolescent Character Strength Interventions.
The present research study will involve investigating the efficacy of large-scale dissemination models of evidence-based character strength interventions in secondary schools in Kenya.
- Trial name
- NCT05365503
- Where
- 3 sites in Kenya
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Shamiri Institute
Diaper Rash, UTI
Diaper Distribution in Low-Income Infants
The adverse effects of poverty at the individual, family, and community level on health outcomes for children are well-established.
- Conditions
- Diaper Rash, UTI, Depressive Symptoms, Stress
- Trial name
- NCT03425851
- Testing
- Diapers, Resources of diaper banks
- Where
- United States
- Sponsor
- Boston Medical Center
Depression
Technology Assisted Programs That Promote Mental Health for Teenagers
The mission of this project is to develop novel systems of care that can provide efficacious, scalable, cost-effective, participant friendly behavioral intervention technologies (BITs) for the prevention of depression in…
- Trial name
- ProjectTECH (NCT01912729)
- Testing
- Networked Peer Support with Peer Guide, Networked Peer Support with Clinician Coach
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Depression, Substance-Related Disorders
Middle School to High School Transition Project: Depression and Substance Abuse Prevention
This study will implement a school-based program to prevent depression, academic failure, and substance use in at-risk adolescents transitioning from middle school to high school.
- Trial name
- CAST-T/HSTS (NCT00071513)
- Testing
- CAST-T/HSTS, Brief Intervention
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of Washington
PTSD, Depression
Violence Prevention for Adolescent Girls With Prior Maltreatment
The purpose of the study is to adapt and test an evidence-based trauma treatment program for adolescent girls with histories of child maltreatment.
- Conditions
- PTSD, Depression, Aggression, Victimization
- Trial name
- GAIN (NCT02765048)
- Testing
- GAIN Program
- Where
- 3 sites in United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Infant, Newborn, Hypoxia, Brain
Optimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE)
The Optimizing Cooling trial will compare four whole-body cooling treatments for infants born at 36 weeks gestational age or later with hypoxic-ischemic encephalopathy: (1) cooling for 72 hours to 33.5°C; (2) cooling for 120…
- Conditions
- Infant, Newborn, Hypoxia, Brain, Hypoxia-Ischemia, Brain, Encephalopathy, Hypoxic-Ischemic
- Trial name
- NCT01192776
- Testing
- Whole-body Cooling
- Where
- 19 sites in United States
- Volunteers
- 364 people
- Sponsor
- NICHD Neonatal Research Network
Dysautonomia, Anxiety
Implementation of Transdx Group for POTS
The proposed intervention is focused on developing and implementing a psychological approach incorporated into a group-based outpatient intervention for pediatric autonomic dysfunction.
- Conditions
- Dysautonomia, Anxiety, Depression
- Trial name
- NCT03185247
- Testing
- Transdiagnostic Group-Based Treatment
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Depressive Disorder, Fatigue Syndrome, Chronic
Glucocorticoid Effects on Cellular Cytokine Release
A variety of hormones and immune system processes are responsible for how the body responds to illness. This study concentrates on how the hormone cortisol effects the release of immune system factors called cytokines.
- Conditions
- Depressive Disorder, Fatigue Syndrome, Chronic, Fibromyalgia, Healthy
- Trial name
- NCT00001415
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
HIV, Depression
Implementation of Collaborative Care for Depression in VA HIV Clinics
HIV Translating Initiatives for Depression into Effective Solutions (HITIDES) is a team-based service to manage depression in Veterans Living with HIV (VLWH).
- Trial name
- HITIDES-H3 (NCT05901272)
- Testing
- Local clinical champion, Learning collaborative, External facilitation
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anxiety, Depression
Mental Health INtervention With Digital APPlications (MIND-APP): Evaluating the Effectiveness of the Tankevirus and Grubl Mental Health Apps
The MIND-APP trial is a 3-arm randomized controlled trial (1:1:1 allocation) conducted fully remotely via a bespoke smartphone research platform.
- Trial name
- MIND-APP (NCT07627204)
- Testing
- Tankevirus, Grubl
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Akershus
Quality of Sleep, Subacute or Chronic Low Back Pain
Association Between Low Back Pain and Quality of Sleep
A prospective study to assess the association between the change in quality of sleep and the change in intensity of pain in Spanish patients seen for subacute or chronic low back pain.
- Conditions
- Quality of Sleep, Subacute or Chronic Low Back Pain, Disability, Catastrophizing
- Trial name
- NCT00906152
- Where
- 2 sites in Spain
- Volunteers
- 437 people
- Sponsor
- Kovacs Foundation
Stress, Psychological, Stress Disorders, Traumatic
Intergenerational Transmission of Traumatic Stress
Millions of U.S. parents have experienced trauma, putting them at risk for maladaptive parenting practices, which then confer vulnerabilities to their children.
- Conditions
- Stress, Psychological, Stress Disorders, Traumatic, Emotion Regulation, Behavior, Child
- Trial name
- NCT05264415
- Testing
- Families OverComing Under Stress (FOCUS) for Early Childhood (FOCUS-EC), Parenting Education Website
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Los Angeles
Learning Disorders, Depression
Move and Feel Good : Effects of Intensive Physical Training on Brain Plasticity, Cognition and Psychological Well-being.
The investigators perform a prospective, randomized, clinical study involving students in education with mood disorders and randomized to an intensive exercise program or a control relaxation activity.
- Conditions
- Learning Disorders, Depression, Anxiety
- Trial name
- Move&FG (NCT02970825)
- Testing
- Exercise, Relaxation
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Migraine
Nutritional Intervention in Migraine
Migraine is a common medical condition. Several studies suggest that obesity and/or weight gain are risk factors for aggravating migraine course, especially increase the frequency of headache episodes.
- Trial name
- NCT02703129
- Testing
- Nutritional intervention
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Federal University of Minas Gerais
Human Immunodeficiency Virus, Risk Reduction
Building Mobile HIV Prevention and Mental Health Support in Low-resource Settings
The purpose of this research study is to provide help and support for mental health and human immunodeficiency virus (HIV) risk reduction among Romanian gay and bisexual men.
- Conditions
- Human Immunodeficiency Virus, Risk Reduction, Alcohol Abuse, Depression, Anxiety
- Trial name
- NCT03912753
- Testing
- Comunică, Education Attention Control
- Where
- Romania
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Columbia University
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