Clinical trials: Depressive Disorders
Overweight, Obesity
Challenge! Adolescent Obesity Prevention
The prevalence of overweight among adolescents (BMI-for-age %tile over the 95th percentile) has more than tripled over the past 3 decades in the US.
- Trial name
- Challenge (NCT03103269)
- Testing
- Challenge! Small Group Intervention, Challenge! Environmental Intervention
- Where
- United States
- Volunteers
- 789 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Depression, Anxiety, Nurse-Patient Relations
Relationship-based Care Model in Pediatrics
Aim: To evaluate whether the application of the Relationship-based Care (RBC) model as a treatment called "Take 5 minutes" (T5M) affects the level of anxiety and depression of the parent, the level of the parent perceived quality…
- Trial name
- NCT04199429
- Testing
- Relationship-Based Care
- Volunteers
- 180 people
- Sponsor
- University of Urbino "Carlo Bo"
Psychiatric Disorder, Major Depressive Disorder
Exploring Blood Plasma Metabolomics: Unraveling the Metabolic Landscape in Treatment-Resistant Adolescent Depression
This study contributes new evidence for the identification of adolescent TRD and sheds light on differing pathophysiologies by delineating distinct plasma metabolic profiles between adolescent TRD and FEDN-MDD.
- Conditions
- Psychiatric Disorder, Major Depressive Disorder, Metabolic Disorder
- Trial name
- NCT06331572
- Testing
- 17-HAMD
- Where
- China
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Depressive Disorder
Paxil Japanese Post Marketing Paediatric Study in Depression (Double-blind, Placebo Controlled Study)
This study is designed to compare the efficacy of oral paroxetine 10 to 40 mg/day (initial dose:10 mg/day) versus placebo administered once daily (after evening meal) for 8 weeks in children and adolescents with major depressive…
- Trial name
- NCT00812812
- Testing
- paroxetine 10mg tablet, paroxetine 20mg tablet
- Where
- 33 sites in Japan
- Volunteers
- 56 people
- Sponsor
- GlaxoSmithKline
Depression Anxiety Disorder
Study on Music Intervention of Non-clinical College Students
The purpose of this trial is to understand whether a mindfulness-integrated volleyball team sports program can effectively intervene in the mental health of college students.
- Trial name
- NCT06658431
- Testing
- music group therapy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ye Zhiyin
Unipolar Depression
Ketamine Trial for the Treatment of Depression
This study is a Randomized Controlled Trial, investigating the safety and efficacy of administration of ketamine as a potential treatment for depression.
- Trial name
- NCT02401139
- Testing
- Ketamine
- Where
- 2 sites in Australia
- Volunteers
- 10 people
- Sponsor
- The University of New South Wales
Depression Anxiety and Co-occurring Rural Youth
Implementing and Evaluating an Internet-based Cognitive Behavior Therapy Intervention in School Settings
This research study examines rural youth's experience of an internet based cognitive behavioral therapy intervention, and their experience of symptoms of depression, anxiety and co-occurring disorders.
- Trial name
- NCT04928001
- Testing
- internet based iCBT program, Youth Thrive
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Montana State University
Adolescent Depression
A Hybrid Psychological Intervention for Depression in Adolescents
This multi-center, randomized controlled trial was conducted to evaluate the efficacy and long-term effects of a novel hybrid psychological intervention, which combines Resilience Theory with the Satir Model, for adolescents…
- Trial name
- NCT07104851
- Testing
- Resilience-Satir Hybrid Intervention, Treatment as Usual (TAU)
- Where
- China
- Volunteers
- 420 people
- Sponsor
- The First Hospital of Hebei Medical University
Depressive Symptoms, Depression
Self-guided Treatment for Adolescents Navigating Depression
The goal of this study is to test whether an investigational mobile app can be a helpful treatment option for adolescents with symptoms of depression.
- Conditions
- Depressive Symptoms, Depression, Depressive Disorder, Depressive Episode
- Trial name
- NCT05462652
- Testing
- Active Intervention
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- Limbix Health, Inc.
Depression in Adolescence, Suicidal Ideation
Social Media Concerns Related to Emotional Experiences in Naturalistic Settings (SCREENS)
The objective of this study is to advance understanding of the relationships between social media use (SMU) and internalizing symptoms among a diverse sample of depressed and/or suicidal youth.
- Conditions
- Depression in Adolescence, Suicidal Ideation, Social Media Addiction, Mental Health Issue
- Trial name
- SCREENS (NCT07278752)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Texas Southwestern Medical Center
Bipolar Disorder, Depression
Early Detection and Prevention of Mood Disorders in Children of Parents With Bipolar Disorder
This study will develop strategies for early detection and prevention of mood disorders and associated impairment in adolescent children of parents with bipolar disorder.
- Trial name
- NCT00338806
- Testing
- Interpersonal psychotherapy for prevention with adolescents, Educational clinical monitoring
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- New York State Psychiatric Institute
Depression, Treatment Resistant Depression
Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression
SHAKTI (from the Sanskrit word for "power") is a 5-year natural history, longitudinal, prospective study of a cohort of 6,000 participants that will help uncover the socio-demographic, lifestyle, clinical, psychological, and…
- Conditions
- Depression, Treatment Resistant Depression, Mood Disorders, Bipolar Disorder
- Trial name
- SHAKTI (NCT06002204)
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Preterm, Mothers
The Effect of Progressive Muscle Relaxation Exercises
Purpose This study was carried out to examine the effectiveness of Progressive Muscle Relaxation (PMR) exercises on mothers' breastfeeding self-efficacy and depression level with preterm infants.
- Trial name
- NCT05453734
- Testing
- Progressive Muscle Relaxation Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul University - Cerrahpasa
Post Intensive Care Syndrome, Narrative Medicine
Effect of Pediatric Intensive Care Unit Diaries on PICS-p
When children become very sick and need to stay in a Pediatric Intensive Care Unit (PICU), it can have a big impact on their recovery and their family's well-being.
- Conditions
- Post Intensive Care Syndrome, Narrative Medicine, Post Traumatic Stress Disorder, Anxiety
- Trial name
- PICS-p (NCT06310109)
- Testing
- PICU diary
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Bambino Gesù Children's Hospital IRCCS
Subthreshold Depression, Young People
TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals.
The purpose of this study is to assess the mechanisms of the effect of transcranial direct current stimulation (tDCS) in alleviating subthreshold depressive symptoms in young individuals, and individualized outcome prediction is…
- Conditions
- Subthreshold Depression, Young People, Transcranial Direct Current Stimulation
- Trial name
- NCT06294184
- Testing
- tdcs lDLPFC, tdcs rVLPFC
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital
Intensive Care Pediatric
Experiences Reported by Siblings of Children Hospitalized in the PICU
The care for a child in pediatric intensive care is recognized as a traumatic experience for the patient and their entourage. The needs and feelings of parents are relatively well supported in the literature.
- Trial name
- SIBCARE (NCT06664333)
- Testing
- Semi-structured interviews
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Major Depressive Disorder (MDD), Adolescent Depression
Predictors of rTMS and Group Therapy Efficacy in Adolescent Depression
This study aims to identify baseline predictors of treatment efficacy in adolescents with Major Depressive Disorder (MDD) undergoing a combined intervention of repetitive transcranial magnetic stimulation (rTMS) and group…
- Trial name
- NCT07283419
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Group Cognitive Behavioral Therapy (CBT)
- Where
- China
- Volunteers
- 163 people
- Sponsor
- The First Hospital of Hebei Medical University
Congestive Heart Failure, Diabetes
Evaluation of Programs of Coordinated Care and Disease Management
This is a Congressionally mandated study. In the original study, 16 demonstration programs provided care coordination services to beneficiaries with chronic illness in Medicare's fee-for-service program.
- Conditions
- Congestive Heart Failure, Diabetes, Coronary Artery Disease, Chronic Obstructive Pulmonary Disease
- Trial name
- Coca (NCT00627029)
- Testing
- Care Coordination
- Where
- 15 sites in United States
- Volunteers
- 18,277 people
- Sponsor
- Mathematica Policy Research, Inc.
Anxiety, Depression
Emotion Focused Family Therapy for Parents of Children With Mental Health Difficulties
Emotion Focused Family Therapy (EFFT) is a promising intervention that aims to teach parents advanced skills to support their child's development of emotion skills and increase their adaptive behaviours, potentially leading to…
- Conditions
- Anxiety, Depression, Behavior Problem
- Trial name
- NCT05603000
- Testing
- Emotion Focused Family Therapy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Guelph
Pain, Anxiety
Impact of Virtual Reality on Pediatric Patients with ESRD on Regular Hemodialysis Through Arteriovenous Fistula.
This case control study will be conducted to study the effectiveness of Virtual Reality technique on pain during arteriovenous cannulation and on reduction of anxiety and depression in Pediatric Patients with ESRD undergoing…
- Trial name
- VR (NCT06675877)
- Testing
- virtual reality camera
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
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