Clinical trials: Dermatology
Autosomal Recessive Congenital Ichthyosis, Skin Barrier Dysfunction
Cholesterol Cream vs Urea Cream for Skin Barrier and Quality of Life in Ichthyosis
This study looks at whether a cream containing 10% cholesterol works better than a cream containing 10% urea for people with autosomal recessive congenital ichthyosis (ARCI), a rare inherited skin condition that causes dry…
- Conditions
- Autosomal Recessive Congenital Ichthyosis, Skin Barrier Dysfunction, Ichthyosis Inherited
- Trial name
- CURE-ARCI (NCT07689435)
- Testing
- 10% Cholesterol Cream, 10% Urea cream
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Institute of Dermatology, Thailand
Atopic Dermatitis
Comparing Aquaphor to Atopiclair and EpiCeram in Children With Mild to Moderate Atopic Dermatitis
The purpose of this study is to compare the efficacy and cost effectiveness of Aquaphor Healing Ointment, Atopiclair and EpiCeram as a monotherapy in mild to moderate AD.
- Trial name
- NCT01093469
- Testing
- Atopiclair Nonsteroidal Cream, Aquaphor Healing Ointment, EpiCeram
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Wake Forest University Health Sciences
Procedural Anxiety, Procedural Pain
VR-PAT for Pain and Anxiety Management During Pediatric Dermatologic Laser Procedures
This study will assess the feasibility and efficacy of our Virtual Reality Pain Alleviation Therapy (VR-PAT) for pain management during pediatric and young adult outpatient laser procedures and evaluate the impact of VR use on…
- Trial name
- NCT05645224
- Testing
- VR-PAT
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Nationwide Children's Hospital
Dermatologic Disease
A Skin Image Reference Tool to Aid Healthcare Providers' Diagnosis
Consented patients will have three images taken of their dermatologic conditions within the Belle.ai software. These images will be uploaded and saved within the Belle software system where a single AI-generated differential list…
- Trial name
- NCT07033169
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Wake Forest University Health Sciences
Dermatitis, Atopic
Spanish Academy of Dermatology and Venereology Registry of Atopic Dermatitis Therapy
The Spanish Registry of Systemic therapy in atopic eczema, BIOBADATOP, assesses drug safety and treatment effectiveness as well as treatment impact on quality of life in children and adults with atopic eczema receiving systemic…
- Trial name
- BIOBADATOP (NCT05674695)
- Testing
- Ciclosporin
- Where
- 9 sites in Spain
- Volunteers
- 2,500 people
- Sponsor
- Fundación Academia Española de Dermatología
Psoriasis
Tunisian National Registry on Psoriasis
National cross-sectional multicentric study to describe the epidemiological characteristics of patients with Psoriasis in Tunisia
- Trial name
- PsoTReg (NCT05258838)
- Where
- Tunisia
- Volunteers
- 1,100 people
- Sponsor
- Dacima Consulting
Plaque Psoriasis
A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
The purpose of this study is to evaluate the efficacy, safety, and drug levels of Deucravacitinib (BMS-986165) in adolescent participants with moderate to severe plaque psoriasis
- Trial name
- POETYK-PsO-Ped (NCT06979453)
- Testing
- Deucravacitinib
- Where
- 133 sites in United States, Argentina and 14 more
- Volunteers
- 366 people
- Sponsor
- Bristol-Myers Squibb
Dermatologic Disease
Addressing Inequity in Dermatology
The objectives of this study are to understand the variation in dermatoses presenting in individuals from different ancestry backgrounds. This will be conducted at multiple NHS hospitals in England.
- Trial name
- NCT06056648
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Manchester
Skin Massage
Exploring the Cutaneous Immune Response to Skin Massage in Early Life
This project aims to study whether regular skin massage in babies induces cutaneous inflammation and whether this inflammatory response is amplified in those receiving daily (vs bi-weekly or no) skin massage over an 8 week…
- Trial name
- CUTIE (NCT07228728)
- Testing
- Skin Massage with Product
- Where
- United Kingdom
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- King's College London
Dermatology/Skin - Other
Photograph Quality Rating Scale Study ("PQRS Study")
Advances in smart phone-based photography (both quality and image transmission) offer the potential to greatly improve access to pediatric dermatologists.
- Trial name
- PQRS (NCT03246945)
- Testing
- Instructions on taking photographs provided, see methods
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Abdominal Pain/Gastrointestinal Issues, Lower Respiratory System Conditions
Clinic Waiting Room-based Study of Swahili Language Artificial Intelligence-driven Symptom Assessments in Tanzanian Primary Health Care Facilities
This study will evaluate the accuracy of the condition suggestions and urgency advice of the Swahili language Ada symptom assessment application (SAA), when symptoms are input by a lay-person user and a medical professional…
- Conditions
- Abdominal Pain/Gastrointestinal Issues, Lower Respiratory System Conditions, Upper Respiratory System Conditions, Mental Health Conditions
- Trial name
- AFYA (NCT04958577)
- Testing
- Ada Waiting Room App (WRA) and Ada Diagnostic Support Application (HDA)
- Where
- Tanzania
- Volunteers
- 109 people
- Sponsor
- Ada Health GmbH
Melanoma
Evaluation of Pigmented Skin Lesions With MelaFind(R) System
The purpose of this clinical trial is to demonstrate that MelaFind®, a new instrument that uses machine vision for non-invasive early detection of cutaneous pigmented malignant melanoma, is safe and effective.
- Trial name
- NCT00434057
- Testing
- MelaFind(R)
- Where
- 2 sites in United States
- Volunteers
- 1,383 people, healthy volunteers welcome
- Sponsor
- MELA Sciences, Inc.
Neurofibromatosis 2, Dermatology/Skin - Other
Cutaneous and Mucosal Manifestations of Neurofribromatosis Type 2 in Children Under 15
.Neurofibromatosis type 2 is an inherently autosomal dominant genetic disease, but cases of mosaicism or de novo mutation are not uncommon. the prevalence is estimated at 1 / 60,000.
- Trial name
- NCT03893643
- Testing
- no intervention
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Vitiligo
Daily Topical Rapamycin for Vitiligo
In current Dermatology practice, options for vitiligo remain limited. The purpose of this study is to determine if once daily dosed topical rapamycin is effective for the treatment of patients with vitiligo.
- Trial name
- NCT05342519
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Skin Cancer Melanoma
AI-Driven Early Detection of Skin Cancer
This study evaluates the feasibility and accuracy of an AI-powered mobile platform (NuvanaDx) for early detection of skin cancer, including melanoma, using smartphone-based imaging.
- Trial name
- Skin Cancer (NCT07144306)
- Testing
- Smartphone-based AI skin lesion analysis (NuvanaDx platform).
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nuvana Healthcare LTD
Eczema, Psoriasis
Use of a Digital Psychotherapeutic App to Reduce Symptom Burden in Dermatology Patients
Skin diseases, despite low mortality, significantly impair quality of life. This randomised controlled trial evaluates the efficacy of a digital toolkit comprising psychotherapeutic strategies in reducing QoL burden in patients…
- Conditions
- Eczema, Psoriasis, Urticaria
- Trial name
- NCT06702293
- Testing
- Digital psychotherapeutic intervention, Healthy365
- Where
- Singapore
- Volunteers
- 690 people
- Sponsor
- National University Hospital, Singapore
URTICARIA
Efficacy of Rupatadine 5, 10 and 20 mg in Chronic Idiopathic Urticaria
The objective of this study is to evaluate the efficacy and safety of rupatadine for the treatment of CIU symptoms.To assess the clinical efficacy of a dose ranging of rupatadine fumarate (5mg, 10mg, and 20 mg) compared with…
- Trial name
- NCT00199238
- Testing
- Rupatadine Fumarate
- Where
- France
- Volunteers
- 248 people
- Sponsor
- J. Uriach and Company
Lichen Planus, Oral
Hydroxychloroquine vs. Clobetasol Rinse to Treat Oral Lichen Planus
This study will compare two treatments for oral lichen planus - hydroxychloroquine (Plaquenil) tablets and clobetasol oral rinse.
- Trial name
- NCT00102557
- Testing
- Hydroxychloroquine
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Eczema, Dermatitis
A Study Comparing the Quality of Life of Patients in the Treatment of Eczema by Pediatric Generalists and Specialists
The purpose of this study is to investigate the differences in the quality of life of patients and caregivers who are treated by general pediatricians versus pediatric dermatologists for eczema (atopic dermatitis or AD).
- Conditions
- Eczema, Dermatitis, Dermatitis, Atopic, Genetic Disease, Inborn
- Trial name
- NCT02916888
- Testing
- Care provided by general pediatrician, Care provided by pediatric dermatologist
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Skin Condition, Dermatology
Application of the Belle.AI Dermatological Image Reference System for Patient Diagnosis in an Active Clinical Setting
The goal of this research study is to test a new, investigational tool that uses artificial intelligence (AI) to help primary care providers assess skin conditions.
- Conditions
- Skin Condition, Dermatology, Dermatology/Skin - Other
- Trial name
- NCT06724627
- Testing
- Dermatology/Skin - Other
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- BelleTorus Corporation