Clinical trials: Desflurane
Emergence Agitation After Desflurane Anesthesia
Gabapentin Oral Solution in Decreasing Desflurane Associated Emergence Agitation
to study the effect of oral gabapentin (5 mg/kg) on emergence agitation after desflurane anesthesia in pediatrics undergoing starbismus surgery
- Trial name
- NCT03347916
- Testing
- Gabapentin Oral Solution [Neurontin]
- Where
- Kuwait
- Volunteers
- 75 people
- Sponsor
- Kuwait Specialized Eye Center
Agitation
ED50 of Dexmedetomidine to Prevent Emergence Agitation in Children
There are several recommended doses of dexmedetomidine for prevention of emergence agitation in children. In this study, the investigators examine ED50 in prevention of emergence agitation after tonsillectomy or adenoidectomy in…
- Trial name
- NCT01374737
- Testing
- Dexmedetomidine
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Seoul National University Hospital
Agitation
Effects of Serotonin Inhibitors on Patient-controlled Analgesia Related Nausea and Vomiting
ED50 of dexmedetomidine for prevention of emergence agitation after tonsillectomy or adenoidectomy in children
- Trial name
- NCT01517438
- Testing
- agitation
- Volunteers
- 21 people
- Sponsor
- Seoul National University Hospital
Heart Arrest
Impact if Desflurane Preconditioning on the Content of the Phospho-GSK-3b in the Rat's Neurons in the Model of I/R
Endpoint implementation of reactions initiated by ischemia is the mitochondrial transition pore permeability. Mitochondria pores opening results in a release of factors triggering apoptosis primarily the cytochrome С Inhibition…
- Trial name
- NCT04287842
- Testing
- Desflurane, Sevoflurane, Cardiac arrest
- Sponsor
- Negovsky Reanimatology Research Institute
Pectus Excavatum
Pulmonary Mechanics During Minimally Invasive Repair of Pectus Excavatum
The aim of the current study was to compare the effects of sevoflurane and desflurane on respiratory mechanics in patients undergoing repair of pectus excavatum.
- Trial name
- NCT01486953
- Testing
- Desflurane, Sevoflurane
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- The Catholic University of Korea
Anesthetics, Inhalation, Neuromuscular Blockade
Effect of Rocuronium and Sugammadex Under Sevoflurane and Desflurane Anesthesia in Children
Sugammadex is the first selective relaxant binding agent approved to reverse certain non-depolarizing neuromuscular drugs in patients 2 years old and above.
- Conditions
- Anesthetics, Inhalation, Neuromuscular Blockade, Anesthesia, General
- Trial name
- NCT03795259
- Testing
- Rocuronium, Sugammadex
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Istanbul University
Anesthesia
Dexmedetomidine and Desflurane Consumption
The aim of this study is to calculate desflurane consumption when combined with intraoperative dexmedetomidine infusion guided by bispectral index (BIS)
- Trial name
- NCT02652312
- Testing
- Dexmedetomidine, Ondansetron, fentanyl
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Theodor Bilharz Research Institute
Kasai Operation, Biliary Atresia
The Comparison of Desflurane and Sevoflurane on Postoperative Recovery and Hepatic Function of Biliary Atresia Patients During Kasai Operation
Biliary atresia (BA) is a perinatal disease of unclear etiology, characterized by inflammation and obliteration of intrahepatic and extrahepatic bile ducts, leading to cholestasis and cirrhosis.
- Trial name
- NCT01443572
- Testing
- desflurane anesthetics, sevoflurane anesthetics
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Paediatrics, General Anaesthesia
Comparison of the Anaesthetic Gases in Maintainance of General Anaesthesia in Paediatrics
Desflurane and Sevoflurane are one of the modern inhalational anaesthetic agents currently in use in anaesthetic practice. The properties of desflurane that has low blood gas solubility coefficient of 0.47 compared to sevoflurane…
- Trial name
- NCT04771962
- Testing
- DESFLURANE AND SEVOFLURANE
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Liver Functions Tests
Desflurane and Sevoflurane in Pediatrics With Elevated Liver Enzymes
It is designed to compare effects of inhaled anaesthetic desflurane and sevoflurane on liver functions in pediatric cancer patients
- Trial name
- NCT04775212
- Testing
- Desflurane, Sevoflurane
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Psychomotor Agitation
The Effect of Dexmedetomidine on Emergence Agitation in Children Undergoing a Surgery Under Desflurane Anesthesia
After genernal anesthesia using sevoflurane or desflurane, the investigators can observe many cases of agiation (over 80%) and despite of no report of long-term complication, agitation is a big issue in PACU for doctors and…
- Trial name
- NCT01578161
- Testing
- Dexmedetomidine, 0.9% Normal Saline
- Where
- South Korea
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Pediatric Acute Respiratory Distress Syndrome, Desflurane
Effect of Desflurane on Pediatric Acute Respiratory Distress Syndrome After Living Donor Liver Transplant Recipients
Biliary atresia is a serious congenital anomaly characterized by persistent and progressive cholestatic jaundice. The incidence of biliary atresia is more common in East Asia, especially China, with an incidence of 2 per 10,000…
- Conditions
- Pediatric Acute Respiratory Distress Syndrome, Desflurane, Biliary Atresia
- Trial name
- EDPARDSLDLTR (NCT05783518)
- Testing
- desflurane, propofol
- Where
- 2 sites in China
- Volunteers
- 165 people
- Sponsor
- Tianjin First Central Hospital
Desflurane Anesthesia
Desflurane in Children With Laryngeal Mask Airway
The purpose of this study is to characterize the airway responses to desflurane during maintenance of and emergence from anesthesia in children whose airways were supported with laryngeal mask airways (LMAs).
- Trial name
- NCT02470442
- Testing
- Sevoflurane/Desflurane, Sevoflurane
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Down Syndrome
The Effects of Inhalational Anaesthetics in Cognitive Functions in Down Syndrome Patients
Recovery of the cognitive functions and recovery features after general anaesthesia in Down syndrome patients. A comparison of Sevoflurane and Desflurane.
- Trial name
- NCT02971254
- Testing
- Sevoflurane, Desflurane
- Where
- Greece
- Volunteers
- 39 people
- Sponsor
- Asklepieion Voulas General Hospital
Entropion
The Effect of Preoperative Ketamine on the Emergence Characteristics in Children Undergoing Entropion Surgery
The investigators evaluate extubation time and recovery profiles in children undergoing entropion surgery.
- Trial name
- NCT02916407
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Inje University
Desflurane Levels
A Pilot Study to Measure Blood Levels of Desflurane in Children
In this feasibility study we will collect blood from indwelling arterial catheters in up to 20 patients undergoing non-emergent surgery with desflurane anesthesia at Children's Hospital of Philadelphia.
- Trial name
- NCT00577369
- Testing
- Desflurane Levels
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Children's Hospital of Philadelphia
Children, Urologic Diseases
Emergence Agitation Between Sevoflurane and Desflurane in Pediatric
Sevoflurane is the volatile anesthetic agent of choice in pediatric surgery. Nevertheless, sevoflurane anesthesia had the high incidence of emergence delirium compared to halothane and isoflurane.Bortone L et al.reported…
- Conditions
- Children, Urologic Diseases, Ambulation Difficulty
- Trial name
- NCT01235143
- Testing
- Desflurane, Sevoflurane
- Where
- Thailand
- Volunteers
- 136 people
- Sponsor
- Prince of Songkla University
Laryngeal Mask Airway
Laryngeal Mask Airway (LMA) Complication in Children
Desflurane is known to be the most pungent of the currently used volatile anesthetics. The investigators tried to find out if desflurane increases the incidence of perioperative upper airway complications in infants and children…
- Trial name
- NCT02644226
- Testing
- Sevoflurane, Desflurane
- Volunteers
- 3,528 people
- Sponsor
- Seoul National University Bundang Hospital
Minimal Flow Anesthesia, Low Flow Anesthesia
Comparison of Minimum Flow and Low Flow Desflurane Anesthesia in Robotic Assisted Laparoscopic Abdominal Surgery
This study aims to compare the use of low fresh gas flow (1 L/min) desflurane anesthesia with minimum fresh gas flow (0.5 L/min) desflurane anesthesia in patients undergoing robotic-assisted abdominal surgery.
- Conditions
- Minimal Flow Anesthesia, Low Flow Anesthesia, Robotic Assisted Laparoscopic Abdominal Surgery
- Trial name
- NCT06520943
- Testing
- blood gas analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Cognitive Dysfunction
Comparison of Desflurane With Sevoflurane for School-age Children in Postoperative Cognitive Function
This study compares desflurane with sevoflurane for school-age children in postoperative cognitive function.
- Trial name
- NCT02909413
- Testing
- Desflurane, sevoflurane
- Volunteers
- 600 people
- Sponsor
- Shengjing Hospital