Clinical trials: Developing Countries
Surgical Procedures, Operative, Artificial Intelligence (AI)
Artificial Intelligence in Surgical Practice in Sudan: National Survey of Doctors
This is a national survey of doctors in Sudan who are involved in providing surgical care. The aim is to understand their awareness, experiences, and opinions about using artificial intelligence (AI) in surgery.
- Conditions
- Surgical Procedures, Operative, Artificial Intelligence (AI), Wounds and Injuries, War Injury
- Trial name
- NASAPS (NCT07138105)
- Testing
- National AI in Surgical Practice Survey - Sudan
- Where
- Sudan
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Sudan Medical Specialization Board
Cyanotic Congenital Heart Disease
Predicting Factors for Mortality in Congenital Heart Disease Patients After Shunt Procedure in Developing Country.
Blalock Taussig (BT) is a palliative procedure that preserves blood circulation to the lungs and alleviates cyanosis in patients with congenital heart diseases and reduced pulmonary blood flow.
- Trial name
- NCT05800691
- Where
- Indonesia
- Volunteers
- 197 people
- Sponsor
- Universitas Sumatera Utara
Asthma
Equivalence of a Human-Powered Nebulizer to an Electric Nebulizer
This is an equivalence study comparing an electric nebulizer with a human-powered nebulizer--one that does not need electricity--in the treatment of mild to moderate asthma exacerbations in a regional clinic in San Salvador, El…
- Trial name
- NCT01795742
- Testing
- Human-Powered Nebulizer
- Where
- El Salvador
- Volunteers
- 110 people
- Sponsor
- Marquette University
Bacterial Infection, Sepsis
Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infants
Approximately one-third of neonatal deaths in developing countries are due to infections acquired through the birth canal and/or exposure to an unclean environment soon after birth.
- Conditions
- Bacterial Infection, Sepsis, Infant, Newborn
- Trial name
- NCT00189384
- Testing
- ceftriaxone, procaine penicillin and gentamicin, oral cotrimoxazole and gentamicin
- Where
- Pakistan
- Volunteers
- 426 people
- Sponsor
- Aga Khan University
Immunity
A Clinical Study to Investigate the Effect of a Partially Hydrolysed Infant Formula With Added Synbiotics on Gut Microbiota Composition and Clinical Effectiveness in Infants at High Risk of Developing Allergy
With the rising prevalence of allergic diseases and the subsequent risk of developing other immune-related disorders, primary prevention of allergy has become a major priority.
- Trial name
- TEMPO (NCT03067714)
- Testing
- Infant formula with added synbiotics, Standard infant formula
- Where
- 59 sites in Belgium, Czechia and 11 more
- Volunteers
- 855 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Low Birth Weight
Efficacy of Continuous Skin to Skin Care (Technique Kangaroo: TK) After Birth for Low Birth Weight (LBW) Infants and Their Mothers in Developing Countries
The purpose of this study is to examine the efficacy of Technique Kangourou (TK) between low birth weight (LBW) infants and their mothers started as soon as possible within 24 hours after birth in developing country.
- Trial name
- EtudeTK (NCT00531492)
- Testing
- TK as soon as possible within 24 hours after birth, Conventional care
- Where
- Madagascar
- Volunteers
- 73 people
- Sponsor
- Foundation for Advanced Studies on International Development
Bone Neoplasms
Localized Osteosarcoma in Upper Egypt: A Clinical Prediction Model
To assess survival outcome of pediatric patients with localized osteosarcoma of the extremities in Upper Egypt, identify factors of prognostic significance for survival, and to determine factors predictive of surgical methods…
- Trial name
- NCT03839095
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Neurological Disorders, Cerebral Malaria
Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC
The impact of neurological disorders is enormous worldwide, and it is increased in poor settings, due to lack of diagnosis and treatment facilities as well as delayed management.
- Conditions
- Neurological Disorders, Cerebral Malaria, Bacterial Meningitis, Central Nervous System Tuberculosis
- Trial name
- Nidiag-Neuro (NCT01589289)
- Testing
- Immunochromatographic HAT tests (DSD), Card Agglutination Trypanosoma Test, TB POC Nucleic Acid Amplification Test (Molbio Diagnostics)
- Where
- Democratic Republic of the Congo
- Volunteers
- 352 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Immunity
A Clinical Study to Investigate the Effect of a Partially Hydrolysed Infant Formula With Added Synbiotics on the Development of Allergic Manifestations in Infants at High Risk of Developing Allergy
With the rising prevalence of allergic diseases and the subsequent risk of developing other immune-related disorders, primary prevention of allergy has become a major priority.
- Trial name
- MAESTRO (NCT03062995)
- Testing
- Infant Formula with added synbiotics, Standard Infant formula
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nutricia Research
Infant Mortality, Morbidity
Vitamin A Supplementation With Bacille Calmette Guerin (BCG) Vaccine
In the present study the investigators wish to address the effects of different doses of vitamin A supplementation in low and normal birth weight infants.
- Trial name
- NCT00168610
- Testing
- Vitamin A
- Where
- Guinea-Bissau
- Volunteers
- 7,600 people
- Sponsor
- Bandim Health Project
Surgical Procedures, Operative
Determining Universal Processes Related to Best Outcome in Emergency Gastrointestinal Surgery: an International Evaluation
A multicentre, international evaluation of emergency abdominal surgery to establish surgical outcomes and identify common, modifiable best practice processes.
- Trial name
- GlobalSurg-1 (NCT02179112)
- Testing
- Emergency Abdominal Surgery
- Where
- United Kingdom
- Volunteers
- 10,745 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Fetal Distress, Stillbirth
Introducing Fetal Scalp Stimulation as an Adjunct to Intermittent Auscultation in Low-Resource Settings.
This study is a pilot study taking place in Moshi, Tanzania at the Kilimanjaro Christian Medical Centre (KCMC). The study aims to introduce fetal scalp stimulation into the intermittent auscultation protocols at KCMC, and to…
- Conditions
- Fetal Distress, Stillbirth, Birth Asphyxia, Acidosis
- Trial name
- NCT02862925
- Testing
- Fetal Scalp Stimulation
- Where
- Tanzania
- Volunteers
- 550 people
- Sponsor
- Duke University
Child Malnutrition
Developing Low-Cost Universal Malnutrition Screening for Low Income Countries - the MAMMS Trial
Acute malnutrition affects 52 million children, costs $2.1 trillion globally, and contributes to 45% of deaths among children under five years of age.
- Trial name
- NCT03967015
- Testing
- Maternal Administered Malnutrition Monitoring System (MAMMS)
- Where
- 3 sites in Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Washington
Surgical Site Infection
Benefit of a Single Preoperative Dose of Antibiotics for the Prevention of Surgical Site Infections
In a rural hospital in Tanzania the rate of surgical site infections (SSI) was 21.6%. Inappropriate choice of antibiotics and of administration time were determined as sole risk factors in this setting.
- Trial name
- SSI2 (NCT00801099)
- Testing
- Amoxicillin/Clavulanic Acid
- Where
- Switzerland
- Volunteers
- 276 people
- Sponsor
- Swiss Tropical & Public Health Institute
Cholera, Typhoid
Studies of Immune Responses to Orally Administered Vaccines in Developing Country
The efficacy and immunogenicity of enteric vaccines have generally been found to be lower in children in the developed than in the developing countries.
- Trial name
- NCT01019083
- Testing
- Control, Zinc Sulphate, Albendazole and Secnidazole
- Where
- Bangladesh
- Volunteers
- 1,016 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Malaria, Pneumonia
Study of Post-Training Supports for Health Workers in Benin
The objective of this study was to determine the effectiveness and cost-effectiveness of a package of interventions to support health workers in Benin (in West Africa) who had been trained to use Integrated Management of…
- Conditions
- Malaria, Pneumonia, Diarrhea, Measles
- Trial name
- NCT00510679
- Testing
- Health worker supports (supervision, job aids, incentives)
- Where
- Benin
- Volunteers
- 1,577 people
- Sponsor
- Centers for Disease Control and Prevention
Diarrhea, Dysentery (Bloody Diarrhea)
Solar Disinfection of Drinking Water
SODISWATER is a European Union funded health impact assessment study investigating the effect of sunlight to inactivate microbial pathogens in drinking water.
- Trial name
- SODISWATER (NCT01082107)
- Testing
- Solar disinfection in transparent containers (plastic bottles)
- Where
- South Africa
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Council for Scientific and Industrial Research, South Africa
Skin Transplantation, Wounds and Injuries
Do Topical Antibiotics Improve Skin Graft Results?
The goal of this study is to see if putting antibiotic ointment on a skin graft when the surgery is being done helps prevent the skin graft from getting infected after the operation.
- Conditions
- Skin Transplantation, Wounds and Injuries, Antibiotic Prophylaxis Surgery
- Trial name
- NCT07286851
- Testing
- Neomycin
- Where
- Bangladesh
- Volunteers
- 142 people
- Sponsor
- LAMB Project
Hypothermia, Newborn
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part V
The overall hypothesis is that plastic bags used in combination with WHO thermoregulation care will reduce the incidence of hypothermia in preterm/low birth weight and full term infants when compared to routine WHO…
- Trial name
- NCT01604460
- Testing
- Resuscitation with torso plastic bag, Resuscitation-no plastic bag
- Where
- Zambia
- Volunteers
- 275 people
- Sponsor
- University of Alabama at Birmingham
Hyperbilirubinemic Encephalopathy
Determining Prevalence of Acute Bilirubin Encephalopathy in Developing Countries
The investigators hypothesize that a new BIND (Bilirubin Induced Neurologic Dysfunction) scoring method adapted for the developing world (BIND II, developed by our team for use by health care workers), with additional…
- Trial name
- NCT01754688
- Where
- Nigeria
- Volunteers
- 624 people
- Sponsor
- University of Minnesota