Clinical trials: Development, Adolescent
Schizophrenia, Autism-Related Irritability
A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents
The purpose of this study is to evaluate the long-term safety and tolerability of Xanomeline and Trospium Chloride for the treatment of psychiatric disorders in children and adolescents
- Trial name
- NCT07424404
- Testing
- KarXT, KarX-EC
- Where
- 104 sites in United States, Australia and 9 more
- Volunteers
- 400 people
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Autism, Autism in Children
Developing a Novel Therapy for Aversive Sensory Experiences in Autism
The goal of this study is to assess whether a new psychological treatment can lead to changes in sensory experiences in autistic young people.
- Trial name
- NCT06682858
- Testing
- Group Cognitive Behavioural Therapy
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- King's College London
T1DM, Brain Development
Brain Health and Development With T1DM
Type 1 diabetes mellitus (T1DM) is typically diagnosed in childhood and over time can lead to complications affecting the retina, heart, kidneys, peripheral nerves, and more recently appreciated, the brain.
- Trial name
- NewT (NCT03335878)
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Autism
Learning Enhancement Through Neurostimulation in Autism
This study will examine whether brain stimulation paired with social skills learning can help teenage boys with autism learn how to make and keep friends. Brain stimulation can enhance learning in some people.
- Trial name
- LENS (NCT02998684)
- Testing
- Active Transcranial Direct Current Stimulation, PEERS Social Skills Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Emotion Regulation, Autism Spectrum Disorder
Equine-assisted Therapy for Therapy-resistant Adolescents With Autism Spectrum Disorders, a Replicated AB-design
The purpose of this study is to assess the (cost)effectivity of Equine assisted Therapy in adolescents with Autism Spectrum disorders.
- Conditions
- Emotion Regulation, Autism Spectrum Disorder, Adolescent - Emotional Problem
- Trial name
- NCT05200351
- Testing
- Equine assisted Therapy (EAT)
- Where
- 3 sites in Netherlands
- Volunteers
- 35 people
- Sponsor
- Karakter Kinder- en Jeugdpsychiatrie
Autism Spectrum Disorder, Autism
Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined.
Autism spectrum disorder (ASD) is a neurodevelopmental condition with core deficits in social communication and behavior, often accompanied by gastrointestinal (GI) and metabolic dysfunction.
- Conditions
- Autism Spectrum Disorder, Autism, Autism Spectral Disorder
- Trial name
- GARM-Autism (NCT07546942)
- Testing
- Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells, Fecal Biomicrome Transplantation (FMT), Ketogenic RESET Diet Protocol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Black Tie Medical, Inc.
Overnutrition, Undernutrition
Early Life Nutritional Exposures and Long-term Health and Cognitive Outcomes
This study aims to investigate the relationship of the various exposures during infancy and childhood on later health and development of adolescents.
- Trial name
- NCT01979770
- Where
- Thailand
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Prodromal Schizophrenia, Psychosis
Feasibility Trial of a Lifestyle Intervention for CHR-P
The present study will assess the feasibility and social validity of an adjunctive health promotion group for youth and clinical high risk for psychosis (CHR-P).
- Conditions
- Prodromal Schizophrenia, Psychosis, Psychological Disorder, Psychological Stress
- Trial name
- NCT05532683
- Testing
- Health Behaviors Group
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of California, Los Angeles
Depression, Autism
Behavioral Activation for Treatment of Depression in Adolescents With Autism
In this study, the investigators will examine the feasibility, acceptability, and preliminary efficacy of a novel, behavior-based approach for treatment of depression symptoms in adolescents with autism spectrum disorder or ASD…
- Trial name
- BA-A (NCT05018169)
- Testing
- BA-A
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Virginia
Kallmann Syndrome, Hypogonadotropic Hypogonadism
Human Menopausal Gonadotropin Combining With Human Chorionic Gonadotropin Treat Congenital Hypogonadotropic Hypogonadism
Observe the therapeutic efficacy of human menopausal gonadotropin combining with human chorionic gonadotropin in adolescent boys with congenital hypogonadotropic hypogonadism.
- Trial name
- NCT02880280
- Testing
- Human Menopausal Gonadotropin, Human Chorionic Gonadotropin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Children's Hospital
Mental Disorders, Severe
Measuring Development of Brain Responses to Vocal Sounds in Babies of Mums With Mental Illness
CAPRI-Voc examines the differences in how speech and environmental sounds are processed in the infant brain as they grow from 9 to 12 months.
- Trial name
- CAPRI-Voc (NCT04350294)
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Autism Spectrum Disorder, Sleep Disturbance
Internet-delivered Cognitive Behaviour Therapy for Sleep Problems in ASD
This trial investigates the behavioural effects of Internet-based Cognitive behaviour therapy for insomnia (CBT-I) in adolescents with autism spectrum disorder with sleep problems. This is a randomised controlled trial.
- Conditions
- Autism Spectrum Disorder, Sleep Disturbance, Insomnia
- Trial name
- NCT03624400
- Testing
- Internet-based CBT-I, Internet-based psychoeducation
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Stockholm University
Unintended Pregnancy, Adolescent Problem Behavior
Multi-site Evaluation of an Evidence-based Positive Youth Development Program
Investigators are carrying out a study to assess the immediate and long-term effects of a positive youth development program (the Teen Outreach Program) on high school youth in Florida.
- Trial name
- NCT02519530
- Testing
- Teen Outreach Program
- Volunteers
- 8,161 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Teacher Help for Children and Youth With Mental Health Disorders
Currently, Canadian school systems are struggling to meet the needs of children with mental health disorders. It is particularly challenging to meet the needs of students with neurodevelopmental disorders (NDDs) within the…
- Conditions
- Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Learning Disabilities
- Trial name
- TeacherHelp (NCT02919215)
- Testing
- Teacher Help Intervention
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- IWK Health Centre
Healthy, Adolescent Development
Discovering Adolescents' Talents and Life Projects as a Key Factor in Their Life Satisfaction
Recent data show a deterioration in the mental health of adolescents, with an increase in anxiety, depression, sleep disturbances, eating disorders, and a significant increase in suicides.
- Trial name
- GENIALADOLES (NCT06473155)
- Testing
- Experimental: Humanistic Integrative Psychotherapy and Identity Exploration (HIP+EYME), Experimental: Humanistic Integrative Psychotherapy, Identity, and Geniotype Exploration (HIP+EYME+GENIOTYPE)
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Besai
Autism Spectrum Disorder
Feasibility and Safety of a Virtual-Reality Based Job Interview Training Tool in Teenagers With High-Functioning Autism
The current project involves the application of a VR job training software. We propose to use an interactive VR job interview practice system, Virtual Reality Job Interview Training (VR-JIT), in youths with ASD at the highschool…
- Trial name
- NCT04773548
- Testing
- VR-JIT
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Depression
Teen Brain Online II: Understanding How Social Media Affects the Teen Brain
There has been much interest in the potential role of social media (SM) use in driving a current mental health crisis among teens, with a dire need for evidence that goes beyond self-report.
- Trial name
- TBO-II (NCT06817993)
- Testing
- Rejection and Acceptance Feedback
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder, Obesity
Semaglutide in Youth With Autism Spectrum Disorder
This study is a 6-month, two-arm, RCT which will evaluate the effectiveness and safety of semaglutide in adolescents aged 12-18 years with autism spectrum disorder (ASD) and obesity.
- Trial name
- GLP1 (NCT07770152)
- Testing
- Glucagon-like peptide-1 receptor agonist：Semaglutide, Lifestyle Management (LSM) Counseling
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism, Asperger's Syndrome
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01919970
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism Spectrum Disorders
Improving Participation of Autistic Children and Adolescents in the Habilitation Process
This project aims to explore the impact of a survey-based and a meeting-based needs assessment models on 7 to 17 year old autistic children's participation in the needs assessment process at the initial reception when enrolled at…
- Trial name
- IMPAC (NCT06381856)
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Örebro County