Clinical trials: Development, Child
DCild Development Disorders, Pervasive, Autistic Disorder
A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Children With Autistic Disorder and Other Pervasive Developmental Disorders (PDD)
The purpose of the study is to evaluate the effectiveness of an oral solution of risperidone (an antipsychotic medication) versus placebo in the treatment of behavioral symptoms in children with Pervasive Developmental Disorders…
- Conditions
- DCild Development Disorders, Pervasive, Autistic Disorder, Developmental Disabilities, Asperger Syndrome
- Trial name
- NCT00261508
- Testing
- risperidone
- Volunteers
- 80 people
- Sponsor
- Janssen-Ortho Inc., Canada
Autism, Autism Spectrum Disorder
Neural Mechanisms of CBT for Anxiety in Autism (Open Pilot Study)
This is an open, pilot study of neural mechanisms of cognitive-behavioral therapy for anxiety in children with high-functioning autism spectrum disorder (ASD).
- Conditions
- Autism, Autism Spectrum Disorder, Anxiety
- Trial name
- NCT02225808
- Testing
- CBT for anxiety in autism
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Child Development
Effect of Infant Formula Intake on Infant Growth From 0 to 6 Months.
From birth to 5 months, milk is the essential and unique food of the newborn. The French National Nutrition Program (PNNS) recommends exclusive breastfeeding "up to 6 months and at least 4 months for a healthy benefit".
- Trial name
- BABYMILK (NCT02997826)
- Testing
- Infantil formula
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Problematic Behavior in Children, Parent-child Problem
Effectiveness of a Foster Parent Intervention: Results of a Trial
The hypothesis of the study is that the intervention leads to a reduction in foster children's externalizing problems and foster parents' parenting stress and that this in turn leads to a reduction in the number of breakdowns of…
- Trial name
- PVO (NCT01821755)
- Testing
- Foster parent intervention
- Where
- Belgium
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Autism Spectrum Disorder
Assessing the Effectiveness of Reciprocal Imitation Teaching in Part C Early Intervention Settings (Sprout Study)
Despite strong consensus that early, specialized intervention for children with Autism Spectrum Disorder (ASD) can have a dramatic impact on outcomes, the public health system's capacity to provide such services is severely…
- Trial name
- NCT05425277
- Testing
- Reciprocal Intervention Teaching (RIT), Daily Routines
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Washington
Autism Spectrum Disorder
Naturalistic Teaching Strategies in Children With Autism
The study will show the effect of naturalistic teaching strategies and picture exchange communication systems in children with an autism spectrum disorder. There will be two groups in this study.
- Trial name
- NCT05359757
- Testing
- Effect of Naturalistic Teaching Strategies in Children with autism spectrum disorder, PECS Therapy only
- Where
- Pakistan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Leukemia
Interleukin-2 in Treating Children Who Have Undergone Bone Marrow Transplantation for Acute Myeloid Leukemia
RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of interleukin-2 in treating children who have undergone bone marrow transplantation…
- Trial name
- NCT00009698
- Testing
- aldesleukin
- Where
- 119 sites in United States, Australia and 4 more
- Volunteers
- 1 people
- Sponsor
- Children's Oncology Group
Insomnia Chronic, Autism Spectrum Disorder
Targeting Insomnia in School Aged Children With Autism Spectrum Disorder
Children with Autism Spectrum Disorder (ASD) and insomnia, and their parent(s) will undergo 4 sessions of behavioral therapy for sleep problems followed by 4 bimonthly booster sessions.
- Trial name
- RECHArge (NCT04545606)
- Testing
- In-Person CBT for insomnia in children with autism, Remote CBT for insomnia in children with autism, Remote sleep hygiene and related education (SHARE) for insomnia in children with autism
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Missouri-Columbia
Hearing Loss, Bilateral
Hearing Intervention Effects on Brain and Language Development in Children With Bilateral Mild Hearing Loss
This is a multicenter, prospective, randomized controlled clinical trial to evaluate the effects of hearing aid intervention on brain and language development in children with bilateral mild sensorineural hearing loss.
- Trial name
- HBD-RCT (NCT07774728)
- Testing
- Behind-the-ear (BTE) hearing aids, Hearing-care educational sessions
- Where
- 12 sites in China
- Volunteers
- 258 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Autism Spectrum Disorder
Mind the Gap (AIR-B3)
There has been a lack of research on the unique needs of families with autism in the African-American and Latino communities. The process of screening, evaluation and treatment for children with autism can be long and arduous…
- Trial name
- MtG (NCT03711799)
- Testing
- Access to services via peer coaching
- Where
- 3 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Health Resources and Services Administration (HRSA)
Aggression, Attention Deficit-Hyperactivity
Metabolic Effects of Antipsychotics in Children
The project aims to describe and compare the outcome of 12 weeks of prospective, randomized treatment with olanzapine, risperidone or aripiprazole on insulin action in skeletal muscle, liver and adipose tissue, abdominal fat…
- Conditions
- Aggression, Attention Deficit-Hyperactivity, Oppositional Defiant Disorder, Pervasive Development Disorders
- Trial name
- MEAC (NCT00205699)
- Testing
- risperidone, olanzapine, aripiprazole
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Washington University School of Medicine
Autism Spectrum Disorder
The Effects of Medical Cannabis in Children With Autistic Spectrum Disorder
Children with autism spectrum disorder (ASD) commonly exhibit comorbid symptoms such as aggression, hyperactivity and anxiety. Data on the effects of cannabidiol rich cannabis extract use for ASD is promising but still limited.
- Trial name
- NCT05212493
- Testing
- Cannabis oil
- Where
- Israel
- Volunteers
- 128 people
- Sponsor
- Assaf-Harofeh Medical Center
Down Syndrome
Relationship Between BMI, Physical Fitness and Motor Skills in Children With Down's Syndrome
Down syndrome is a congenital condition which includes physical mental, and functional abnormalities. It arises from defect involving chromosome 21, usually an extra copy (trisomy 21).
- Trial name
- NCT05904821
- Where
- Pakistan
- Volunteers
- 169 people
- Sponsor
- Riphah International University
Development Coordination Disorder
Active Video Games in Children With DCD
Developmental Coordination Disorder (DCD) is a condition that affects a child's ability to perform coordinated motor activities and may also impact visual perception and motor planning skills.
- Trial name
- NCT07631832
- Testing
- Active Video Game Training, Conventional Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- ZEYNEP KOLİT
Autism Spectrum Disorder
The AMOR Method: Resilience Training for Parents of Children With Autism
We will evaluate whether a resilience training program which includes group and individual parent training will be effective in improving optimism and resiliency in parents of young children with autism spectrum disorders (ASD).
- Trial name
- NCT03513419
- Testing
- The AMOR Method
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
Cognitive Support Technology for Postsecondary Students With Autism Spectrum Disorder
This study will fill important knowledge gaps in the availability of best practices that use innovative methods to integrate the cognitive and vocational needs of students with Autism Spectrum Disorder (ASD) who will be…
- Trial name
- NCT04980963
- Testing
- Cognitive Support Technology (CST)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kent State University
Molar Incisor Hypomineralization
Pain Perception and Anxiety With Virtual Reality vs Tell-Show-Do in Children With MIH
This pilot crossover randomized clinical trial aims to compare the effect of distraction using Virtual Reality (VR) versus the Tell-Show-Do (TSD) technique on pain perception and anxiety in children aged 6-12 with Molar Incisor…
- Trial name
- NCT07052019
- Testing
- Virtual Reality Distraction, Tell-Show-Do Technique
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Short Stature
The Dosage Exploration Study of PEG-rhGH for Treating Short Stature in Prepubertal and Pubertal Children
This study is dedicated to addressing the lack of research on the most effective dosage of long-acting growth hormone for children with short stature.
- Trial name
- NCT06768411
- Testing
- PEG-rhGH, GnRHa
- Volunteers
- 240 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Developmental Delay
Development and Effectiveness of Home-based Programs for Preschool Children With Developmental Delay
Early intervention refers to the provision of early detection, early diagnosis, and early intervention for infants and young children with special needs.
- Trial name
- NCT02115334
- Testing
- professional therapists delivering the PHPA, parents executing the PHPA, health education
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Down Syndrome
Neurodevelopmental Treatment for Balance and Mobility in Children With Down Syndrome
The goal of this clinical trial is to evaluate whether Neurodevelopmental Treatment (NDT) can improve balance, mobility, walking capacity, and functional independence in preschool children with Down syndrome.
- Trial name
- NCT07653399
- Testing
- Neurodevelopmental Treatment (NDT)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul Nisantasi University
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