Clinical trials: Development, Child
Neurodevelopmental Disorders, Autism
Early Life Anemia and Children's Risk of Neurodevelopmental Disorders: National and Regional Register-based Studies
The overall project aim is to study children's neurodevelopmental outcomes (including diagnoses of autism, ADHD, and intellectual disability) following exposure to maternal anemia during pregnancy or anemia during the first year…
- Conditions
- Neurodevelopmental Disorders, Autism, ADHD, Intellectual Disability
- Trial name
- NCT06199362
- Where
- Sweden
- Volunteers
- 2,400,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder (ASD, Parental Behaviors
Effectiveness of Video-feedback for Positive Parenting with Children At Risk of ASD
Improving parent-child interactions benefits child development and parents' perception of their competencies for childrearing and support for child learning and development, which in turns positively impacts on parental emotional…
- Trial name
- VIFEPOPA (NCT06604988)
- Testing
- Video-feedback intervention to promote positive parenting
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Barcelona
Attention Deficit Disorder With Hyperactivity, Autistic Disorder
Methylphenidate in Children and Adolescents With Pervasive Developmental Disorders
This study will evaluate the efficacy and safety of methylphenidate for treating hyperactivity, impulsiveness, and distractibility in 60 children and adolescents with Pervasive Developmental Disorders (PDD).
- Conditions
- Attention Deficit Disorder With Hyperactivity, Autistic Disorder, Pervasive Development Disorders
- Trial name
- NCT00025779
- Testing
- methylphenidate, guanfacine
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder
Comparsion of SPARK and Fundamental Motor Training
It was a Randomized Clinical Trial.Data will be collected from Life care rehabilitation and special child facility.The study was completed within 6 months after approval of synopsis.The calculated sample size, through WHO sample…
- Trial name
- NCT05986760
- Testing
- SPARK
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- khadija liaquat
Early Childhood Development
Evaluation of Scaling Up Early Childhood Development in Zambia
In Zambia, 40% of children under five years of age are stunted and 6% are wasted. While the Zambian government has focused on child nutrition in recent years, more focus on holistically improving early child development (ECD) is…
- Trial name
- SUpErCDZ (NCT03991182)
- Testing
- SMAGs trained on ECD curriculum, Head women trained on ECD curriculum, Head women led parent groups
- Where
- 3 sites in Zambia
- Volunteers
- 1,108 people, healthy volunteers welcome
- Sponsor
- Boston University
Neurodevelopmental Disorders (NDD), Preschool Child Development
Efficacy of a Group-based and Digital Parent Sleep Intervention in HK Preschoolers With NDDs
Neurodevelopmental disorders (NDDs) in preschoolers are frequently accompanied by persistent sleep disturbances, such as delayed sleep onset and reduced sleep duration, which exacerbate behavioral problems, impair cognitive…
- Conditions
- Neurodevelopmental Disorders (NDD), Preschool Child Development, Sleep
- Trial name
- NCT07822490
- Testing
- Parent-based Group Face-to-face Intervention, Digital Self-help Intervention
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Autism Spectrum Disorder
Open Label Phase I hCT-MSC in Toddlers With Autism Spectrum Disorder
This is a single site, prospective study of one intravenous infusion of human umbilical cord tissue-derived mesenchymal stromal cells (hCT-MSC) in toddlers with autism spectrum disorder (ASD).
- Trial name
- TACT (NCT04294290)
- Testing
- hCT-MSC infusion
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Autism Spectrum Disorder
Social Skills Training Group Effectiveness in Adolescents With Autism Spectrum Disorder
Autism spectrum disorders (ASD) is a neurodevelopmental disorder characterized by persistent deficits in social communication and social interaction across multiple contexts, and the presence of restricted, repetitive behavior…
- Trial name
- NCT05857813
- Testing
- Program for the Education and Enrichment of Relational Skills (PEERS®)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Traumatic Brain Injury, Child Development
Heart Rate Variability in Children With Traumatic Brain Injury
Using a prospective cohort of children admitted to the PICU, the investigators will determine HRV monitoring is feasible, if a decreased HRV in the 7 days following moderate or severe TBI in children is associated with a worse…
- Trial name
- HRV-TBI (NCT03701620)
- Testing
- HRV monitoring
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- St. Justine's Hospital
Autism
Effect of Milk Oligosaccharides and Bifidobacteria on the Intestinal Microflora of Children With Autism
The purpose of this study is to determine the tolerability of dietary supplements and if these supplements can promote a healthy bacterial environment in the intestines of children with autism spectrum disorders and…
- Trial name
- NCT02086110
- Testing
- Synbiotic, Prebiotic
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, Davis
Develop a Nomogram
Development and Validation of a Nomogram Predicting the Probability of in Hirschsprung Children Following Surgery
Postoperative soiling is a common complication following Hirschsprung disease [HSCR] surgery. The aim of this study was to develop a nomogram for predicting the probability of postoperative soiling in patients aged >1 year…
- Trial name
- NCT06025188
- Testing
- training set
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Tongji Hospital
Autism Spectrum Disorder, ASD
Cord Blood Infusion for Children With Autism Spectrum Disorder
This is a single site, prospective, randomized, double-blind study of a single intravenous autologous or allogeneic, unrelated cord blood (CB) infusion in children ages 2-7 years with Autism Spectrum Disorder (ASD).
- Conditions
- Autism Spectrum Disorder, ASD, Autism, PDD
- Trial name
- Duke ACT (NCT02847182)
- Testing
- Cord Blood Infusion
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Joanne Kurtzberg, MD
Autism
Secretin for the Treatment of Autism
Many drugs used to treat autism target specific symptoms, such as hyperactivity and aggressiveness. Few drugs target the core autistic symptoms of impaired social interaction and communication.
- Trial name
- NCT00065962
- Testing
- secretin, synthetic porcine, secretin, biologically derived porcine
- Where
- 2 sites in United States
- Volunteers
- 85 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Osteogenesis Imperfecta
Evaluation of the Benefits of Adaptive Physical Activity in Children and Adolescents With Osteogenesis Imperfecta
Osteogenesis imperfecta (OI) is a rare genetic disorder of increased bone fragility and low bone mass. It is conceivable that children and adolescents with OI are less active than healthy peers because of frequent fractures…
- Trial name
- MOVE-OI (NCT04119388)
- Testing
- Adapted sports practices
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Child Development, Social Protection
Strong Families, Thriving Children "Sugira Muryango"_Activity C
The proposed study will test the effectiveness of the Strong Families, Thriving Children "Sugira Muryango" program as delivered by community based workers and aligned with the Rwandan social protection system.
- Trial name
- NCT02510313
- Testing
- Sugira Muryango
- Where
- Rwanda
- Volunteers
- 2,911 people
- Sponsor
- Boston College
Autism Spectrum Disorder
Assessing the Impact of Probiotic Supplementation in Children Diagnosed With Autism Spectrum Disorder: the PROBI-O-TISM Study
Children with autism spectrum disorder (ASD) present with stereotyped behaviors and often with comorbidities including gastrointestinal symptoms and sleep disturbances.
- Trial name
- (PROBI-O-TISM) (NCT06906068)
- Testing
- Three strains of Lactobacillus: L. acidophilus CL1285®, L. casei LBC80R® and L. rhamnosus CLR2®
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Valérie Marcil
Development, Child
A Smartphone Application for Screening of Developmental Disorders in Children
The detection of developmental disorders in the child is often late because the parents do not have the information necessary to consult at the first clinical signs.
- Trial name
- NCT04958174
- Testing
- web-application
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Weprom
Autism Spectrum Disorder
Effect of a Casein and Gluten Free Diet in Mexican Children With Autism Spectrum Disorder
Assess the effect of a casein-free and gluten-free diet on gastrointestinal symptoms, clinical variables, and the composition of the intestinal microbiota in Mexican children with autism spectrum disorder.
- Trial name
- NCT06556290
- Testing
- Gluten free and casein free diet
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- University of Guadalajara
Chromosome Disorders
Noninvasive Prenatal Diagnosis: Using Fetal Cells From Maternal Blood
This purpose of this study is to develop noninvasive methods of prenatal diagnosis. Fetal cells can be found in maternal blood. This study is designed to isolate these fetal cells from a sample of the pregnant woman's blood and…
- Trial name
- NCT00064597
- Where
- 5 sites in United States
- Volunteers
- 3,500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder
Building Better Bridges Randomized Control Trial
In this study, the investigators will randomize 20 families per site (across 4 sites) to be in the BBB Transition Passport Only Group or BBB Intervention Group.
- Trial name
- (AIR-B3) (NCT03445520)
- Testing
- Intervention Coaching Group
- Where
- 3 sites in United States
- Volunteers
- 375 people
- Sponsor
- Health Resources and Services Administration (HRSA)
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