Clinical trials: Development, Child
Fragile X Syndrome, Autism Spectrum Disorder
Alpha Auditory Entrainment for Cognitive Enhancement and Sensory Hypersensitivity in Youth With Developmental Disorders
Fragile X Syndrome (FXS) is a complex neurodevelopmental disorder caused by a mutation on the X chromosome. Scientists have investigated FXS extensively in both humans and animals.
- Conditions
- Fragile X Syndrome, Autism Spectrum Disorder, Autistic Disorder, Asperger Syndrome
- Trial name
- ENTRAIN (NCT06227780)
- Testing
- Alpha Auditory Entrainment
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Insomnia, Autism
Sleep in Children With Autism and Intellectual Disability
Purposes: Establish proof-of-concept for home polysomnography in the assessment of sleep disorders among prepubertal school children with autism and intellectual disabilities combined; To explore the diagnostic yield of…
- Conditions
- Insomnia, Autism, Intellectual Disability
- Trial name
- SLEEP-AID IT (NCT06403969)
- Testing
- Applied Behavior Analysis
- Volunteers
- 15 people
- Sponsor
- Värmland County Council, Sweden
Multiple Sclerosis
Effects of a Multiple Sclerosis Relapse Therapy on Offspring Neurocognitive Development and Behaviour
Introduction: Fetal exposure to glucocorticoids (GCs) used to induce fetal lung maturation in women threatened by premature labour is known to induce aberrations in brain development and stress sensitivity, cognitive dysfunction…
- Trial name
- MS-Children (NCT04832269)
- Testing
- Exposure to methylprednisolone during pregnancy
- Where
- 2 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Jena University Hospital
Autistic Disorder
An Evaluation of Low Level Laser Light Therapy for Autistic Disorder 2
The purpose of this study is to determine whether the Erchonia HLS Laser is effective in the treatment of irritability associated with autistic disorder in children and adolescents aged five (5) to twelve (12) years.
- Trial name
- NCT04895605
- Testing
- Erchonia HLS Laser
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Erchonia Corporation
Developmental Coordination Disorder
Effects of a Highly Intensive Balance Therapy Camp in Children With Developmental Coordination Disorder
The main objective of this clinical trial is to investigate the short (immediately after intervention) and medium term (three month) effects of a highly intensive, comprehensive postural control 6-day therapy camp in school-aged…
- Trial name
- NCT07096817
- Testing
- Highly intensive individualized balance therapy
- Where
- Belgium
- Volunteers
- 35 people
- Sponsor
- Hasselt University
Autism, Autism Spectrum Disorder
Environmental Influence on Mental Illness Via Modifications of Genomes and Metabolomes in Adolescents With Autism
The aim of the study is to enrich the understanding of the physiological mechanisms that predispose autistic adolescents to mental illness.
- Trial name
- ENIGMA-I (NCT06299618)
- Where
- 3 sites in Ireland, Romania and 1 more
- Volunteers
- 400 people
- Sponsor
- University College Cork
Intellectual Disabilities (F70-F79), Down Syndrome (DS)
Using Technologies to Promote HEalthy Lifestyles in Adolescents With Intellectual Disabilities
IDHEApp will implement various educational technology tools and work with the families, teachers and caregivers to increase physical activity (PA) and improve healthy eating.
- Conditions
- Intellectual Disabilities (F70-F79), Down Syndrome (DS), Autism Disorder
- Trial name
- IDHEAPP (NCT07101523)
- Testing
- mHealth
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Seville
Autism Spectrum Disorder
Improving Daily Living Skills in People With Autism Spectrum Disorder Through a Personalised Serious Game
This study evaluates the efficacy of a rehabilitation intervention for people with Autism Spectrum Disorder through an individualised serious game developed for improving skills related to a specific daily living activity…
- Trial name
- NCT04295746
- Testing
- Serious Game ShopAut
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federico II University
Autism Spectrum Disorders
A Study of a Developmental,Individual-Difference,Relationship-Bases/Floortime Intervention for Children With Autistic
Thirty eight autistic spectrum disorder children age 2-6 years recruited into the study. The new treatment intervention is based on the DIR Model. Parents will be coached at the start and then every 3-4 months for 1 year.
- Trial name
- DIR (NCT00954213)
- Testing
- DIR/Floortime parent intervention
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Attention Deficit Hyperactivity Disorder
Effects of Attention Training on Children
Using a double-blind, randomized controlled design to investigate the therapeutic effects of interactive attention training for children with Attention Deficit Hyperactivity Disorder who are receiving conventional rehabilitation…
- Trial name
- NCT04375059
- Testing
- using interactive attention training system
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Neurodevelopmental Disorders, Developmental Delay
Development of Motility and Cognition in Infants
PILKE study uses wearables for assessing motor development in infants in order to define functional growth trajectories in the normal infants and infants at risk of neurological compromise.
- Conditions
- Neurodevelopmental Disorders, Developmental Delay, Development, Infant, Child Development
- Trial name
- PILKE (NCT05527080)
- Testing
- physiotherapy, brace
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Amblyopia, Anisometropic, Amblyopia Strabismic
Validation of New Virtual Reality Treatment for Children With Lazy Eye Using the Vedea Amblyopia Therapy (VAT)
The purpose of this clinical study is to validate the effectiveness of the Vedea Amblyopia Therapy (VAT) as a treatment for children with lazy eye.
- Conditions
- Amblyopia, Anisometropic, Amblyopia Strabismic, Amblyopia
- Trial name
- VAT (NCT05620173)
- Testing
- Vedea Amblyopia Therapy (VAT), Occlusion therapy
- Where
- 2 sites in Netherlands
- Volunteers
- 74 people
- Sponsor
- Vedea Healthware BV
Child Behavior, Child Health
The Healthy Child Development Program Study
This study conducts a preliminary test of an intervention program delivered in the home to assist families of preschool-age children with social, emotional, and behavioral development, and the acquisition of healthy lifestyle…
- Conditions
- Child Behavior, Child Health, Child, Preschool, Parents
- Trial name
- NCT04622969
- Testing
- Healthy Child Development Program
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Child Development Disorders, Pervasive
Risperidone Pharmacokinetics in Children With Pervasive Developmental Disorder (PDD)
The purpose of this research is to study the pharmacokinetics of risperidone in a group of pediatric patients with Pervasive Developmental Disorder (PDD).
- Trial name
- NCT00147394
- Testing
- Risperidone
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Sepsis, Septic Shock
Evaluation of Blood Protein O-GlcNAcylation Levels in Children
Stimulation of O-GlcNAcylation has been shown to be beneficial in several acute pathologies and different animal models, such as haemorrhagic and septic shock, and ischaemia-reperfusion (cerebral and cardiac).
- Conditions
- Sepsis, Septic Shock, Development and Health, Metabolism Changes
- Trial name
- CHANCE (NCT06754696)
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Infant Development, Temperament
Turkish Version of Infant Movement Motivation Questionnaire
Purpose: It is the examination of the Infant Movement Motivation Questionnaire of the validity and reliability of Turkish. Pretest: Participants were informed about the aims of the study and fill in a consent form.
- Conditions
- Infant Development, Temperament, Early Intervention, Infant Behavior
- Trial name
- NCT04384796
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Child Development
Youth Leaders for Early Childhood Assuring Children Are Prepared for School
Worldwide about 88 million children drop out of primary school annually. One of the contributory factors is a lack of school readiness among young children, their families and their teachers.
- Trial name
- LEAPS (NCT02645162)
- Testing
- Community-based Preschool
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Autism Spectrum Disorder, Autism
Parent Telehealth Intervention for Children With Autism
As a result of the COVID-19 pandemic, telecoaching/telepractice models are of urgent importance. Given this, parents in the study will receive parent coaching through weekly video calls.
- Trial name
- NCT04501588
- Testing
- Responsive training with no video feedback, Responsive training with video feedback
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Autism Spectrum Disorder
Predicting Treatment Response to Memantine in Autism Using Magnetic Resonance Spectroscopy
Memantine, an N-methyl-D-aspartate receptor antagonist, has been explored as a possible therapeutic agent that reduces the excitatory (glutamate) - inhibitory (gamma amino-butyric acid, GABA) imbalance in autism pathology and…
- Trial name
- NCT02811627
- Testing
- Memantine, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Child Development
Effects of Fundamental Motor Skills Program on Motor and Cognitive Abilities
School age child development is a range from 6 to 12 years of age. During this time period observable differences in height, weight, and build of children may be prominent.
- Trial name
- NCT06198205
- Testing
- Fundamental motor skills, Regular after school program
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
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