Clinical trials: Development, Child
Autism Spectrum Disorders
Intestinal Permeability in Children With Autism Spectrum Disorder
In recent years, increasing attention has been directed toward the role of the gut-brain axis in the pathogenesis of neurodevelopmental disorders, particularly Autism Spectrum Disorder (ASD).
- Trial name
- IP-ASD (NCT07032857)
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- University of Bari
Developmental Disability, Developmental Dyslexia
Postural Control, Grip Strength and Body Posture in Children With Intellectual Disability and Dyslexia
This study investigates physical changes in children with Dyslexia and Intellectual Disability. Participants divided into three groups and Body Posture, Postural Control and Hand Grip Strengths was evaluated.
- Conditions
- Developmental Disability, Developmental Dyslexia, Intellectual Disability
- Trial name
- NCT04250701
- Testing
- Body Posture Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ahmet Emir
Hypertension
A Study to Evaluate the Efficacy and Safety of Eplerenone in the Treatment of Hypertension in Children.
To evaluate the efficacy, safety, and toleration of eplerenone in the treatment of children aged 6 to 16 years with high blood pressure. The study will last approximately 10 weeks and about 320 patients will participate.
- Trial name
- NCT00147589
- Testing
- Eplerenone
- Where
- 41 sites in United States, Dominican Republic and 3 more
- Volunteers
- 320 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Electrical Status Epilepticus in Sleep
Electrical Status Epilepticus in Sleep: Response of Neuropsychological Deficits and Epileptiform Activity to Clobazam Treatment
Electrical status epilepticus in sleep (ESES) is a pattern of abnormal discharges in the electroencephalogram (EEG). Children who have this pattern present seizures and neuropsychological regression.
- Trial name
- ESES-Clobazam (NCT02127918)
- Testing
- ESES treated with clobazam
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Boston Children's Hospital
Child Development, Mother-Infant Interaction
Mother-infant Bonding During COVID-19
This study will assess whether the promotion of emotional exchange between mother and infant during the first four months of life improves primarily mother-child early relational health (ERH) and secondarily child…
- Conditions
- Child Development, Mother-Infant Interaction, Relation, Parent-Child
- Trial name
- NCT04531618
- Testing
- Emotional Exchange (EE), Newborn Care (NC)
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Columbia University
Autism, Social Communication
Parent-implemented Social Communication Treatment in Autism
An accumulation of research evidence has pointed to parent-implemented communication intervention as effective in reducing the severity of social communication deficits in autistic preschoolers.
- Conditions
- Autism, Social Communication, Speech Therapy, Parenting
- Trial name
- NCT05635760
- Testing
- Group-based Parent-implemented Social Communication Training, Self-learning-based Parent-implemented Social Communication Training
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 112 people
- Sponsor
- Chinese University of Hong Kong
Duchenne Muscular Dystrophy, Gait Disorders in Children
Quality and Independence of Gait Classification Scale for DMD (QIGS-DMD)
The aim of this study was to develop a reliable and valid gait classification scale for Duchenne Muscular Dystrophy (QIGS-DMD). The items of the QIGS-DMD were designed based on the literature review considering existing…
- Trial name
- NCT05564962
- Testing
- Quality and Independence of Gait Classification Scale for Duchenne Muscular Dystrophy (QIGS-DMD)
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Hacettepe University
Children With Cerebral Palsy
Analysis of Trunk and Center of Mass Control Development During Gait in Children With Cerebral Palsy (VERTEBRAL)
During the acquisition of posturokinetic abilities such as walking, postural control of the trunk is of paramount importance. Indeed, its development is strongly linked to the overall motor function of children.
- Trial name
- VERTEBRAL (NCT06320288)
- Where
- France
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Autism Spectrum Disorder
Sensory and Connectivity Abnormalities in Autism Spectrum Disorders
Study the neural substrates of autism spectrum disorders using neuroimaging methods such as MEG/EEG/MRI.
- Trial name
- NCT00956579
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Language Delay, Developmental Language Disorders
Effectiveness of Early Parent-Based Language Intervention
The purpose of the study is to examine the effectiveness of a highly-structured parent-based language intervention group program for two-year-old children with language delay.
- Trial name
- NCT00625261
- Testing
- Heidelberg Parent-based Language Intervention HPLI
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Heidelberg University
Social Determinants of Health, Health Knowledge, Attitudes, Practice
NASCITA Italian Birth Cohort Study
The NASCITA study (NAscere e creSCere in ITAlia) was created to improve the understanding of the health status of Italian children early on and how it is affected by social and health determinants.
- Conditions
- Social Determinants of Health, Health Knowledge, Attitudes, Practice, Development, Child, Mental Disorders
- Trial name
- NASCITA (NCT03894566)
- Testing
- No intervention - birth cohort study
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Autistic Children With Sensory Processing Abnormalities
Comparison of Effectiveness of Home Based Sensory Interventions Along With Standard Therapy Versus Standard Therapy Alone in Autistic Children With Sensory Processing Abnormalities
Around 69-95% of children with Autistic Spectrum Disorder are known to have sensory processing abnormalities .Tackling these problems would help in better quality of life, both for the parents and the children.
- Trial name
- NCT02491645
- Testing
- Sensory interventions
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Anemia, Iron Deficiency, Vitamin A Deficiency
Iron and Vitamin A in School Children
The WHO recommended intermittent iron supplementation as a strategy for prevention of anemia and iron deficiency among school age children.
- Conditions
- Anemia, Iron Deficiency, Vitamin A Deficiency, Cognitive Development, Helminthic Infection
- Trial name
- IronVitA (NCT04137354)
- Testing
- Intermittent iron supplement, High-dose Vitamin A supplement
- Where
- Ethiopia
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- University Ghent
Speech, Language Developmental Delay From Hearing Loss
Comparative Effects of Play Based Therapy and Functional Communication Training in Speech-language Delayed Children
The purpose of this study is to compare the play based therapy and functional communication training in speech-language delayed children 2-6 years old.
- Trial name
- NCT05749315
- Testing
- Play Based Therapy, Functional Communication Training
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Sehat Medical Complex
Cerebral Palsy Children, Motor Disabilities
Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy
The goal of this clinical trial is to learn if a therapist training program can help providers in Part C Early Childhood Settings use powered mobility (PM) with young children who have cerebral palsy (Gross Motor Function…
- Conditions
- Cerebral Palsy Children, Motor Disabilities, Developmental Disability, Rehabilitation
- Trial name
- NCT07220590
- Testing
- Therapist Training on Powered Mobility Implementation, Powered Mobility Intervention for Child-Caregiver Dyads
- Where
- 3 sites in United States
- Volunteers
- 70 people
- Sponsor
- Oregon Health and Science University
Nutritional Deficiencies
Development and Health of Rural Chinese Children Fed Meat as a Daily Complementary Food From 6-18 Mos of Age
Inadequate feeding of infants and toddlers impairs physical and cognitive development and is a major contributor to early childhood infectious disease illnesses and preventable mortality.
- Trial name
- NCT00726102
- Testing
- Meat, Cereal, fortified rice cereal
- Where
- United States
- Volunteers
- 1,488 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder, Child Development Disorders, Pervasive
Social Robots and Board Games for Children With Autism Spectrum Disorder
This pilot randomized controlled trial evaluates the effectiveness of combining social robot-assisted intervention with physical board games to improve socio-emotional skills in children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT07775937
- Testing
- Social Robot-Assisted Board Game Intervention, Conventional Occupational Therapy
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Investigating Social Competence in Youth With Autism
Our treatment, SENSE Theatre, combines several well-documented, effective behavioral strategies and theatre techniques. The proposed project will extend previous findings showing improving improvement in memory for faces.
- Trial name
- NCT03368001
- Testing
- SENSE Theatre, Tackling Teenage Together
- Where
- 3 sites in United States
- Volunteers
- 318 people
- Sponsor
- Vanderbilt University Medical Center
Anemia, Iron-deficiency
The Effect of Anemia in Infancy on the Microbiome and Systemic Metabolism
Serum and fecal samples were collected from infants at either 6-7 m of age or 12-13 m of age. Serum and feces were analyzed locally for hemoglobin status or evidence of parasites, and standard of care was provided.
- Conditions
- Anemia, Iron-deficiency, Iron Deficiency Anemia
- Trial name
- NCT03377777
- Testing
- No intervention
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Growth & Development
An Integrative Approach to Improve Child Outcomes Through Research-based Parent and Teacher Interventions
The purpose of this study is to learn whether a combination of two research-proven programs, a responsive caregiving parenting program and a teacher training program, will have an effect on infants' and toddlers' language…
- Trial name
- NCT03431545
- Testing
- PALS and, BEECH, Control condition
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
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