Clinical trials: Development, Child
Autism Spectrum Disorder
A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder
The purpose of this study is to demonstrate the feasibility of a 9-week, randomized trial of N-acetylcysteine (NAC) compared to placebo in 14 children (age 5 to 12 years) with Autism Spectrum Disorder (ASD) and a moderate level…
- Trial name
- NAC (NCT03008889)
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Emory University
Goal-Setting
Feasibility of an Implementation Strategy for a Physical Activity Program in Rural Middle Schools
The investigators aim to build on the pilot study data looking at the feasibility of implementation of Goal Setting alongside Hoosier Sport at two schools (Eastern Greene Middle School and White River Valley Middle School).
- Trial name
- NCT07859033
- Testing
- Goal-Setting in Sport-Based Youth Development, No Goal-Setting Program
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Indiana University
Mourning,, Grief,
Bereaving, But Not Alone : the Development and Actualization of a Mutual Aid Group for Children Who Have Lost a Parent.
The methodology of this clinical trial is based on the realisation of a group intervention with children who lost a parent. Interviews preintervention and postintervention with participants will be done as well.
- Conditions
- Mourning,, Grief,, Bereavement.
- Trial name
- NCT01573689
- Testing
- Group intervention based on mutual aid.
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Université de Montréal
Gestational Diabetes Mellitus, Pregnancy Outcome
GDM and Its Consequences in Mothers and Offsprings
Gestational diabetes mellitus (GDM) is one of the most common disorders which occured during pregnancy. GDM is not only associated with short-term maternal and fetal adverse outcomes, but also related to a wide range of long-term…
- Conditions
- Gestational Diabetes Mellitus, Pregnancy Outcome, Neurodevelopment, Immune Development
- Trial name
- GDMCMO (NCT04529889)
- Where
- China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Tuberculosis, Severe Acute Malnutrition
Development of a Diagnostic Prediction Score for Tuberculosis in Hospitalized Children With Severe Acute Malnutrition (TB-Speed SAM)
TB-Speed SAM is a multicentric, prospective diagnostic cohort study conducted in two countries with high and very high TB incidence (Uganda and Zambia).
- Trial name
- NCT04240990
- Testing
- Development of a score and algorithm for TB treatment decision in hospitalised children with SAM.
- Where
- 3 sites in Uganda, Zambia
- Volunteers
- 603 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Development
Neurodevelopmental Outcomes of Preterm and Term Children
This study will utilize two validated tools for assessing child development and behavior, to investigate the outcomes for children born preterm compared with those born at full term.
- Trial name
- NCT02309697
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism Spectrum Disorder
Sensory Integration Versus Fine Motor Intervention in Children With Autism
Clinically, infants with Autism spectrum often display gross motor delays in supine, prone, and sitting skills in their first year of life.
- Trial name
- NCT04696133
- Testing
- fine motor skills, sensory integration
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Infant Health, Child Development
Infant Development and Early Aquatic Stimulation
The objective of this study is to assess the feasibility of an aquatic stimulation protocol for infants up to one year of age. The main questions to be answered are: Is the aquatic stimulation program, which involves recruitment…
- Trial name
- NCT07204613
- Testing
- Aquatic stimulation for child development
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Autism Spectrum Disorder
A Mixed Methods Investigation of Equine-assisted Occupational Therapy for Children With Autism
Children with autism spectrum disorders (ASD) often participate in equine-assisted interventions, where practitioners partner with horses to improve the health and well-being of the clients they serve.
- Trial name
- NCT03493347
- Testing
- Equine-assisted Occupational Therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Colorado State University
Child Development Disorder
Effects of CIMT With and Without Robotic Gloves in Children With Hemiplegic CP
This study investigates the impact of CIMT, with and without robotic gloves, on hand dexterity and grip strength in children with hemiplegic CP, aiming to enhance motor skills and promote independence in daily activities.
- Trial name
- NCT07248735
- Testing
- CIMT with robotic glove, CIMT with standard rehabilitation
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Attention Deficit Disorder With or Without Hyperactivity (ADHD), Autism Spectrum Disorder (ASD)
Characterize the Links Between Sleep, Emotional Dysregulation and Learning in Neurodevelopmental Disorders.
The aim of this protocol is to disentangle the links between symptoms of emotion dysregulation, sleep disorders and cognitive deficits by measuring the effects of an emotional induction task on childrens' sleep with autism…
- Trial name
- SOM-EMO-TND (NCT06479668)
- Testing
- Trier Social Stress Task
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Dwarfism, Growth Disorder
Study of Luteinizing Hormone-Releasing Hormone Analog (LHRHa) in Pubertal Patients With Extreme Short Stature
Children with extreme short stature (height) and their families often experience significant psychological stress related to concerns about adult height.
- Trial name
- NCT00001190
- Testing
- Deslorelin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Developmental Disability, Autism Spectrum Disorder
Association Between Motor Skills and Sensory Profiles in Children With Typical and Atypical Development Aged 4 to 11 Years
Background and Justification Childhood developmental disorders, such as Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), and Developmental Coordination Disorder (DCD), pose significant challenges…
- Conditions
- Developmental Disability, Autism Spectrum Disorder, Development Coordination Disorder, Attention Deficit Disorder With Hyperactivity
- Trial name
- MOTISEN (NCT06764810)
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Autism, Autism Disorder
How Virtual Reality Can Help Neurodivergent Children Improve Their Attention
The goal of this study is to determine whether playing a virtual reality (VR) game can help neurodivergent children pay attention for extended periods.
- Conditions
- Autism, Autism Disorder, ADHD - Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder
- Trial name
- Attend-VR (NCT07341204)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Offspring, Adult, Lifestyle
Factors Affecting Newborn Body Composition and Later Health in Helsinki Birth Cohort 2018-2022
In Helsinki Birth Cohort 2018-2022 a large, longitudinal and well-phenotyped birth cohort of infants and their parents will be established.
- Conditions
- Offspring, Adult, Lifestyle, Obesity, Childhood, Pregnancy Related
- Trial name
- HeBiCo (NCT03765684)
- Where
- Finland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Autism Spectrum Disorder, Complication of Prematurity
Correlation of CXCR4 Expression in Premature Infants With a Diagnosis of Autism at 24 Months
Preterm children are at increased risk for autism spectrum disorders, with an estimated rate of 10%. In the US, about 1 in 8 pregnancies ends with a premature birth.
- Trial name
- ASD-CXCR4 (NCT01686685)
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Suicidal Ideation, Suicidal and Self-injurious Behavior
A Comparison of Two Brief Suicide Prevention Interventions Tailored for Youth on the Autism Spectrum
Rates of suicide have increased significantly over the past two decades, particularly among youth. Compared to the general population, autistic people are significantly more likely to think about suicide, attempt suicide, and die…
- Conditions
- Suicidal Ideation, Suicidal and Self-injurious Behavior, Suicide, Autism Spectrum Disorder
- Trial name
- NCT05398250
- Testing
- Safety Planning Intervention tailored for Autistic Individuals, Safety Planning Intervention Tailored for Autistic Individuals Plus Structured Follow-Up Contacts
- Where
- 5 sites in United States
- Volunteers
- 1,665 people
- Sponsor
- University of North Carolina, Chapel Hill
Congenital and Acquired Developmental Disabilities
Tele-rehabilitation in Subjects With Congenital and Acquired Developmental Disabilities
The COVID-19 emergency has led to the complete closure of all rehabilitation services, both public and/or private, across Italy, including the region of Tuscany.
- Trial name
- TABLETOSCANA (NCT06219447)
- Testing
- VRRS Home Tablet or Medico Amico Kids APP
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Giovanni Cioni
Gliosis, Child Obesity
Building Research for Intervention Development in Gliosis and Eating Habits
The goal of this study is to 1) use magnetic resonance imaging (MRI) to evaluate the effect of nutritious foods on inflammation in the human hypothalamus of children and 2) assess the feasibility and acceptability of nutritious…
- Conditions
- Gliosis, Child Obesity, Eating
- Trial name
- BRIDGE (NCT06870578)
- Testing
- Diet modification
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Washington
Williams Beuren Syndrome, Williams Syndrome
Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants
The goal of this observational natural history study is to better characterize development, transition to adulthood, health and behavior of individuals diagnosed with Williams syndrome (WS) or carrying other variants of 7q11.23…
- Conditions
- Williams Beuren Syndrome, Williams Syndrome, Williams Beuren Region Duplication, Dup7
- Trial name
- NCT06930417
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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