Clinical trials: Development, Child
Infant Development
Oral Exploration of Objects and Food Diversification
Eating difficulties in infants and young children are defined as all the difficulties in feeding oneself in an appropriate and satisfactory manner.
- Trial name
- OPENING (NCT05157633)
- Testing
- Controls
- Where
- France
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Child Mental Health, Behavioral Symptoms
Wellbeing and Resilience Among 1-3 Years Old Children of Mothers with Complex Mental Health Problems: a Pragmatic Clinical Trial of Online VIPP-SD Vs. Care As Usual
Children of parents with severe mental disorders have an increased risk of mental disorders themselves, with more than half of this population diagnosed with a mental health condition during their life time.
- Conditions
- Child Mental Health, Behavioral Symptoms, Child of Impaired Parents
- Trial name
- WellCom (NCT06795347)
- Testing
- Online VIPP-SD, Care As Usual
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Southern Denmark
Post Partum Depression
Adaptation and Pilot Testing of Web and Mobile Interface for the VID-KIDS Intervention
COVID-19 has placed unprecedented strains on parents impacted by toxic stress (depression, addiction, intimate partner violence, and poverty) and reluctant to see mental health-service providers in home/clinic due to fears of…
- Trial name
- VID-KIDS (NCT04818047)
- Testing
- VID-KIDS Intervention Program
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Genetic Disorder, Asperger Disorder
Pediatric Patients With Metabolic or Other Genetic Disorders
Background: Some patients with unusual genetic conditions are referred to the National Institutes of Health (NIH). They may not be eligible to join current research studies.
- Conditions
- Genetic Disorder, Asperger Disorder, Autism Spectrum Disorder, Fragile X Syndrome
- Trial name
- NCT02769949
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pharmacokinetics, Voriconazole
Development of Voriconazole Pharmacokinetics and Metabolism in Children and Adolescents
The death rate in children from the invasive fungal infection called aspergillosis is more than 50%. Voriconazole is the first-line therapy for this infection.
- Trial name
- NCT01976078
- Testing
- Midazolam/Ranitidine/Esomeprazole
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Children's Hospital Los Angeles
Autism Spectrum Disorder, Autism
Efficacy, Safety, and Tolerability Study of Oral Full-Spectrum MicrobiotaTM (CP101) in Subjects With Autism Spectrum Disorder and Associated GI Symptoms (SPROUT)
Adolescent autism spectrum disorder subjects with associated GI symptoms will be randomized to receive oral dosing of CP101 capsules in Treatment Group I or matching placebo capsules in Treatment Group II.
- Conditions
- Autism Spectrum Disorder, Autism, ASD, Autistic Thinking
- Trial name
- SPROUT (NCT03829878)
- Testing
- CP101
- Sponsor
- Finch Research and Development LLC.
Autism, Autism Spectrum Disorder
Exploring Virtual Reality As an Intervention for Food Selectivity: a Clinical Trial
Food selectivity is a common challenge among children with Autism Spectrum Disorder (ASD), with significant impacts on their nutrition and well-being.
- Trial name
- NCT06656585
- Testing
- Individual food selectivity protocol, Traditional food selectivity protocol
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder
Testing a Novel Parenting Intervention for Children With Autism
This study will investigate the acceptability and preliminary effectiveness of training parents to use a structured communication intervention that is aimed towards helping children with autism spectrum disorder (ASD).
- Trial name
- PAREint (NCT04574206)
- Testing
- Elaborative Reminiscence (ER), Present Tense Talk (PTT)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- City, University of London
Autism Spectrum Disorders
The Swedish Versions of ADOS and ADI-R: Psychometric Validation
Autism spectrum disorders (ASD) are early onset chronic conditions coined by deficits in social reciprocity, communication and stereotypic interests and activities.
- Trial name
- NCT01854333
- Testing
- ADOS module 1-4 or ADI-R
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Goal-Setting
Feasibility of an Implementation Strategy for a Physical Activity Program in Rural Middle Schools
The investigators aim to build on the pilot study data looking at the feasibility of implementation of Goal Setting alongside Hoosier Sport at two schools (Eastern Greene Middle School and White River Valley Middle School).
- Trial name
- NCT07859033
- Testing
- Goal-Setting in Sport-Based Youth Development, No Goal-Setting Program
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Indiana University
Autism Spectrum Disorder, Minimally Verbal Ability
Explore the Therapeutic Effect of Theta Burst Stimulation on Emotion Regulation in Autism With Minimally Verbal Ability or Intellectual Disability
The investigator would like to investigate the impact of theta-burst stimulation over left DLPFC in autism with minimally verbal ability or intellectual disability
- Conditions
- Autism Spectrum Disorder, Minimally Verbal Ability, Intellectual Disability
- Trial name
- NCT06974838
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Congenital Hypothyroidism, Hearing Loss
The Prevalence of Hearing Loss Among Children With Congenital Hypothyroidism
Congenital hypothyroidism (CH) occurs in 1:4000 live births. Neurological disturbances like speech delay, motor delay and lower IQ were reported in children with CH.
- Trial name
- NCT01223638
- Testing
- Audiometry
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Solid Tumor, Childhood, Brain Tumor, Pediatric
Social Emotional Development in Young Children With Cancer
Many children with cancer are diagnosed in early childhood, and as such, will likely miss key social experiences such as participation in preschool or kindergarten, playing on playgrounds, and other normative experiences.
- Trial name
- NCT03086421
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- St. Jude Children's Research Hospital
Autism
Meeting the Needs of Young Hispanic Autistic Children
Purpose of the Study: The goal of this clinical trial is to find out if a technique called the "mutual gaze procedure" used in a Culturally and Linguistically Responsive adaptation of Pathways Early Intervention (CLR-Pathways) is…
- Trial name
- NCT06733584
- Testing
- Culturally and Linguistically Responsive Pathways Parent-Mediated Intervention without Mutual Gaze, Culturally and Linguistically Responsive Pathways Parent-Mediated Intervention
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas at Dallas
Autism Spectrum Disorder, Restricted Behavior
Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth
The purpose of this open label trial is to examine the preliminary feasibility, acceptability, and effectiveness of a 12-week behavioral intervention program (1 hour/week) to treat insistence on sameness (e.g., difficulty…
- Conditions
- Autism Spectrum Disorder, Restricted Behavior, Autism
- Trial name
- M-PRT-IS (NCT06362733)
- Testing
- Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Feeding; Difficult, Newborn, Pre-Term
Effect of Co-morbidities on the Development of Oral Feeding Ability in Pre-term Infants
The aim of this study is to investigate the effect of co-morbidities on the timing of the achievement of full oral feeding in a cohort of pre-term infants and to evaluate their mode of feeding and feeding status at the time of…
- Trial name
- NCT04812249
- Testing
- Clinical assessment
- Volunteers
- 160 people
- Sponsor
- Assiut University
Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC)
Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics
This is a large-scale observational study aiming to evaluate the long-term effectiveness and safety of Fecal Microbiota Transplantation (FMT).
- Conditions
- Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC), Crohn Disease (CD), Irritable Bowel Syndrome (IBS)
- Trial name
- NCT07261826
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Chen QiYi
Growth Hormone Deficiency
National Cooperative Growth Study in CKD
The purpose of this study is to learn whether growth hormone being administered to children with Chronic Kidney Disease is effective and if it has any side effects.
- Trial name
- NCGS (NCT00616278)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Davis
Developmental Coordination Disorder
The Effect of Virtual Reality on Motor Functioning and Participation Abilities Among Children With DCD
The subjet of this study is to explore the effect of using virtual reality environment at the clinic and at home (using Timocco) on the motor and participation abilities of children with DCD (Developmental Coordination Disorder).
- Trial name
- NCT02504385
- Testing
- Virtual Reality Timocco, Conventional OT intervention
- Volunteers
- 30 people
- Sponsor
- Clalit Health Services
Death, Diarrhea
Drinking Water Chlorination and Child Survival in Rural Kenya
The purpose of the study is to estimate the effect of community-wide provision of water treatment (chlorine) solution on all-cause child mortality and on infectious disease related child mortality.
- Conditions
- Death, Diarrhea, Child Development
- Trial name
- NCT04020965
- Testing
- Water Treatment, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 46,212 people, healthy volunteers welcome
- Sponsor
- Tufts University
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