Clinical trials: Development, Child
Asthma, Obesity
Reducing Socioeconomic Disparities in Health at Pediatric Visits
This research project is aimed to assess the effectiveness and impact of a pediatric-based intervention aimed at reducing low-income families' unmet material needs (food, housing, employment, childcare, household heat, education…
- Conditions
- Asthma, Obesity, Health Care Utilization, Health Care Disparities
- Trial name
- WECARE01 (NCT02451059)
- Testing
- WE CARE survey, WE CARE Community Resource Handout, Patient Navigator
- Where
- 6 sites in United States
- Volunteers
- 1,205 people
- Sponsor
- Boston Medical Center
Cleft Palate Children
Effect of Infant Sign Training on Speech-language Development
Children born with a cleft lip and palate (CLP) are known to be at risk for speech-language disorders that impact academic and social emotional growth.
- Trial name
- NCT06143254
- Testing
- Infant sign training, Verbal training
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Obesity, Overweight
Development of Melt Organic Baking Fat for Reducing Child Obesity
The purpose of this study is to compare the effects of a cooking oil on metabolic rate, appetite, and metabolic risk markers.
- Conditions
- Obesity, Overweight, Pediatric Obesity
- Trial name
- NCT02346994
- Testing
- Melt Test Blend 3.2, Corn Oil
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Columbia University
Autism Spectrum Disorder (ASD)
High Definition Transcranial Direct Current Stimulation of Right Inferior Frontal Gyrus to Improve Social Impairments in Children with Autism
The goal of this clinical trial is to learn if high definition transcranial direct current stimulation (HD-tDCS) of right inferior frontal gyrus works to improve social impairments in children with autism spectrum disorder (ASD).
- Trial name
- NCT06723522
- Testing
- HD-tDCS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Central South University
Autism Spectrum Disorder, Depression
Group Depression Treatment for Autistic Youth
Higher rates of depression are reported by autistic adolescents as compared to their non-autistic peers, which is problematic given adverse outcomes (e.g., negative self-esteem, lower academic performance) that are associated…
- Conditions
- Autism Spectrum Disorder, Depression, Suicidal Ideation, Self Esteem
- Trial name
- NCT05430022
- Testing
- Autism-adapted Group Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University Medical Center
Physical Inactivity, Cerebral Palsy
Effects of Physical Activity on Prescription (PAP) as a Health-enhancing Intervention in People With Disabilities
Physical inactivity is an increasing problem in the general population in society. However, in people with disabilities, inactivity is even more frequently reported.
- Conditions
- Physical Inactivity, Cerebral Palsy, Autism, Autism Spectrum Disorder
- Trial name
- PAP (NCT05867940)
- Testing
- Physical activity on prescription
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Region Skane
Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD)
Social Skills Group Training ("KONTAKT") for Children and Adolescent With High-functioning Autism Spectrum Disorders
This trial investigates the behavioral effects of manualized social skills training (KONTAKT) in children´s and adolescents with high-functioning autism spectrum disorder with psychiatric comorbidity in a RCT, multicenter study.
- Conditions
- Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), Anxiety, Depression
- Trial name
- KONTAKT-RCT (NCT01854346)
- Testing
- Social skills group training, KONTAKT
- Where
- Sweden
- Volunteers
- 296 people
- Sponsor
- Karolinska Institutet
Autism, Asperger's Disorder
Mercury Chelation to Treat Autism
This study will examine whether DMSA, an oral chelating agent that removes mercury and other metals from the body, is beneficial for children with autism.
- Conditions
- Autism, Asperger's Disorder, Child Development Disorders, Pervasive
- Trial name
- NCT00376194
- Testing
- DMSA
- Where
- United States
- Sponsor
- National Institute of Mental Health (NIMH)
COVID-19
This Study Investigate the Impact of Maternal COVID-19 Infection During Birth on the Childrens' Physical and Mental Development.
This study investigates the impact of the maternal COVID infection during birth on the children's development: physical and mental outcomes.
- Trial name
- Coronababies (NCT05430594)
- Where
- Hungary
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Autism, Autistic Disorder
Randomized Control Trial of Using Tongue Acupuncture in Autistic Spectrum Disorder Using PET Scan for Clinical Correlation
We aimed to use Tongue Acupuncture (TAC) to assess for any change in brain function.
- Trial name
- NCT00355329
- Testing
- Tongue Acupuncture (Procedure)
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder, Social Communication
RCT to Evaluate Social Skills in Children With Autism Using VR Technology (SoCaVR)
The goal of this randomized clinical trial is to compare and learn about Virtual Reality (VR) in children with autism/Autistic children.
- Trial name
- SoCaVR (NCT06453629)
- Testing
- Floreo VR, VR Control, VR Control Crossover
- Where
- 17 sites in United States
- Volunteers
- 117 people
- Sponsor
- Floreo, Inc.
Autism Spectrum Disorder, Autism
The Effect of Exercise Practices on Hyperactivity Levels in Children With Autism Spectrum Disorder
The aim of this study is to examine the effect of vestibular and proprioceptive exercise practices on the hyperactivity level in children with autism spectrum disorder.
- Trial name
- NCT06415539
- Testing
- classical physical therapy program, exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Autism Spectrum Disorder, Social Skills
Effects of Therapy Dogs on Social Behavior in Group Social Skills Instruction With Children With Autism
Animal-Assisted Interventions (AAI) can increase social behavior in children with autism spectrum disorder (ASD), although the mechanism by which this occurs remains elusive.
- Trial name
- NCT03873831
- Testing
- Animal-assisted intervention, Social skills group
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Down Syndrome, Child Obesity
HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome
The goal of this project is to evaluate an adapted health promotion program, HomeGrown, designed to improve the health of young children with Down syndrome by supporting families in making healthy home environmental changes.
- Trial name
- HomeGrown (NCT07296861)
- Testing
- The HomeGrown, Waitlist
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Intellectual Disabilities (F70-F79), Autism
Optimizing Dimensions of Reinforcement
This study is designed to better understand how certain features of reinforcement affect learning and motivation in individuals with intellectual and developmental disabilities (IDD).
- Trial name
- NCT07137273
- Testing
- Operant Conditioning Tasks with Reinforcement Manipulations
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Auburn University
Acute Lymphoblastic Leukemia, Leukemia, Acute Myeloid (AML), Child
Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant
This study will evaluate pediatric patients with malignant or non-malignant blood cell disorders who are having a blood stem cell transplant depleted of T cell receptor (TCR) alfa and beta cells that comes from a partially…
- Conditions
- Acute Lymphoblastic Leukemia, Leukemia, Acute Myeloid (AML), Child, Lymphoma, Non-Hodgkin, Myelodysplastic Syndrome
- Trial name
- NCT02065869
- Testing
- BPX-501 T cells, Rimiducid
- Where
- 4 sites in Italy, United Kingdom
- Volunteers
- 187 people
- Sponsor
- Bellicum Pharmaceuticals
Molar Incisor Hypomineralization
Restoration of Permanent Molars Affected With (MIH) Using Composite Restorations or Preformed Metal Crowns
The aim of this study is to compare clinical outcome of using direct esthetic composite restorations in managing MIH cases and the use of preformed metal crowns.
- Trial name
- NCT04658602
- Testing
- Preformed stainless steal crown cemented by glass ionomer lutting cement (Ketac cem,3M Espe)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Nada Mahmoud Abd El-Azim Mohamed
Congenital Hypothyroidism, Metabolic Syndrome
Metabolic Risk Assessment in Prepubertal Children With Congenital Hypothyroidism
We propose a multicenter prospective study to define the prevalence and severity score of metabolic syndrome in a prepubertal pediatric cohort with congenital hypothyroidism, compared to a healthy and normal-weight pediatric…
- Trial name
- IpoMet (NCT07126353)
- Testing
- prospective observational study (clinical, hormonal and auxological data)
- Where
- Italy
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Buzzi Children's Hospital
Autism Spectrum Disorder, Developmental Delay
Can Novel Telemedicine Tools Reduce Disparities Related to Early Identification of Autism
In this study, the investigators are trying to find new ways to screen for autism spectrum disorder (ASD) in young children. The investigators want to see if people like pediatricians can screen children for ASD while a…
- Trial name
- NCT03847337
- Testing
- Telehealth-Screening Tool for Autism in Toddlers (STAT), Telehealth-Autism Spectrum Disorder-Pediatrics (ASD-PEDS)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Vanderbilt University Medical Center
Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder
Home Play-based Intervention for Parents and Infants
The goal of this clinical trial is to learn whether a 12-week home-based intervention (Sociometric Play-based Remediation of Individual Neurodevelopmental Trajectories (SPRINT)) helps support parenting and the development of…
- Conditions
- Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder, Premature Birth, Global Developmental Delay
- Trial name
- SPRINT (NCT07716072)
- Testing
- SPRINT Intervention, Waitlist Protocol
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Nanyang Technological University
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