Clinical trials: Development, Child
Autism Spectrum Disorder
An Integrated Nutrition Intervention to Promote Healthy Eating Habits for Children With ASD
There is an unmet need for nutrition interventions that address both autism spectrum disorder (ASD) specific feeding challenges and unbalanced eating habits among children with ASD to prevent future chronic health conditions.
- Trial name
- NCT05194345
- Testing
- Autism Eats nutrition intervention, We Can! enhanced usual care
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of South Florida
Autism Spectrum Disorder
PRISM Intervention Study
This research study, Personalized, Responsive Intervention Sequences for Minimally Verbal Children with Autism (PRISM), is designed to maximize language outcomes for limited-language preschoolers, thereby lowering the risk of…
- Trial name
- NCT03883139
- Testing
- JASPER, DTT (Discrete Trial Training)
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- University of California, Los Angeles
Child Rearing, Reproductive Behavior
Age 12 Follow-up of Early Preventive Intervention (Memphis)
To examine the impact of prenatal and infancy home visiting by nurses from child age 2 through 12.
- Conditions
- Child Rearing, Reproductive Behavior, Risk Reduction Behavior
- Trial name
- MemphisY12 (NCT00438165)
- Testing
- home visitation
- Where
- United States
- Volunteers
- 609 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Early Childhood, Neurodevelopment, Early Childhood, Anthropometry
Environmental Pollutants in Pregnancy - IoMumNEXT
Globally 12.6 million people, including 1.7 million children under the age of 5, die each year from environmental-related illnesses.
- Trial name
- IoMumNEXT (NCT06226311)
- Testing
- Data collection, Diagnostic Test: Urinary
- Where
- Portugal
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Child Behavior, Child Development
A Pilot Study of Teacher-Child Interaction Training - Universal in Head Start
This pilot study aims to implement and evaluate Teacher-Child Interaction Training - Universal (TCIT-U), an empirically-supported classroom-based intervention aimed at improving child behavior and social-emotional skills through…
- Conditions
- Child Behavior, Child Development, Child Behavior Problem
- Trial name
- TCIT-U (NCT04075071)
- Testing
- Teacher-Child Interaction Training - Universal
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Child Development
Effects of Hold-Relax and Muscle Energy Techniques for Hamstring Flexibility
The most important aspect of physical fitness is flexibility, which can be greatly impacted by bad posture. Long periods of sitting in school going children can cause the hamstring muscles to shorten because they bend the knee.
- Trial name
- NCT06198036
- Testing
- Hold-Relax Technique, Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Development, Child
Assessment of Developmental Status and Locomotor Balance in Healthy Children.
The aim of this study is to assess developmental milestones and balance in children in Pakistan. We are using Ages and Stages Questionnaire for developmental milestones and Timed up and Go test for balance.
- Trial name
- NCT05649436
- Where
- Pakistan
- Volunteers
- 500 people
- Sponsor
- Riphah International University
Molar Incisor Hypomineralisation, Enamel Hypoplasia
Effect of Resin Infiltration on Hypersensitivity and Satisfaction in Children With Enamel Defects
This study evaluates the effect of resin infiltration on dental sensitivity, quality of life, and satisfaction in children aged 7-14 with enamel defects in their front teeth.
- Conditions
- Molar Incisor Hypomineralisation, Enamel Hypoplasia, Dental Hypersensitivity
- Trial name
- NCT07118111
- Testing
- Resin infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gizem Tıraşçı
Physical Activity, Fundamental Motor Skills
An Intervention to Improve Motor Skills in Young Children
The goal of "PLAY" is to adapt and test a developmentally appropriate intervention delivered on a mobile app to parents, with the goal of teaching fundamental motor skill (FMS) proficiency to their preschool-aged children (ages 3…
- Conditions
- Physical Activity, Fundamental Motor Skills, Development, Child, Self-regulation
- Trial name
- PLAY (NCT03901300)
- Testing
- Fundamental Motor Skills App, Unstructured Physical Activity App
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Complications of Prematurity
Prematurity Related Risks of Cognitive Impairment at School Age
The main purpose of this study is to better evaluate prematurely born children cognitive development at school age, with regards to birth conditions but also to social situation, intra family relationships, and modalities of…
- Trial name
- NEORIS (NCT02054507)
- Testing
- Cognitive evaluation (Wechsler IV tests)
- Where
- 2 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jean Michel Hascoet
Autism
Randomized Study of Fluoxetine in Children and Adolescents With Autism
OBJECTIVES: I. Evaluate the efficacy of fluoxetine on social and language deficits, global severity and compulsive dimensions of children and adolescents with autism. II.
- Trial name
- NCT00004486
- Testing
- fluoxetine
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism Spectrum Disorder
Tracking Intervention Effects With Eye Tracking
This pilot study examines concurrent and predictive relationships between eye tracking and clinical outcomes during a 16-week behavioral intervention (PRT) for children with ASD.
- Trial name
- NCT02856061
- Testing
- Pivotal Response Treatment
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Yale University
Autism Spectrum Disorder
Intelligence Quotient Assessment in Children With Autistic Spectrum Disorders.
The aim of this study is to assess the cognitive strengths and weaknesses of children with autism and the possible effect of age and IQ on Stanford-Binet Intelligence Scale, 5th Edition.
- Trial name
- NCT04066673
- Testing
- Stanford-Binet Intelligence Scale, 5th Edition
- Volunteers
- 40 people
- Sponsor
- Assiut University
Autism Spectrum Disorder, Autism
Genetic Contributions to Autism Spectrum Disorders
This study is working towards gaining a better understanding of the genetic and environmental factors involved in autism spectrum disorders (ASD), which includes autism, pervasive developmental disorder (PDD), and Asperger's…
- Conditions
- Autism Spectrum Disorder, Autism, Asperger's Syndrome, Pervasive Developmental Disorder
- Trial name
- NCT01160783
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder (ASD
Combination of Supplements for Treating Autistic Spectrum Disorder
A pilot study to compare the efficacy of a combination of apitherapy supplements versus placebo in children with autistic spectrum disorder.
- Trial name
- APITSA (NCT06756711)
- Testing
- A combination of apitherapy and plant extracts
- Where
- 2 sites in Romania
- Volunteers
- 40 people
- Sponsor
- Fundatia Bio-Forum
Down Syndrome, Congenital Heart Disease
Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS)
The study objective is to compare neurodevelopmental (ND) and behavioral outcomes between children with Down syndrome (DS) who had complete atrioventricular septal defect (CAVSD) repair and children from the same clinical sites…
- Trial name
- CHILD-DS (NCT05312177)
- Testing
- Stanford Binet Intelligence Scales, Fifth Edition, Vineland Adaptive Behavior Scales Third Edition, Peabody Picture Vocabulary Test, Fifth Edition
- Where
- 14 sites in United States, Canada
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Autism Spectrum Disorder
Comparing Two Different Emotion Therapies for Autistic Youth and Young Adults
Too few clinicians are able and willing to help autistic patients. A recent review identified challenges to mental health service delivery in autism, including a lack of interventions designed for community implementation and…
- Trial name
- NCT06158581
- Testing
- The Emotion Awareness and Skills Enhancement Program, The Unified Protocol
- Where
- 2 sites in United States
- Volunteers
- 470 people
- Sponsor
- University of Pittsburgh
Language Development
Evaluating the Impact of Story Starters on Children's Language Development
The aim of this project is to evaluate whether Beanstalk's 'Story Starters' intervention is effective in boosting vocabulary and grammatical development in young children.
- Trial name
- NCT03268928
- Testing
- Story Starters Intervention, Wait-list Control
- Where
- United Kingdom
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Julian Pine
Music Therapy
Effects of Music Therapy on Sensory Processing, Adaptive Behavior and Social Interaction
The purpose of our study is to examine the effects of music therapy on sensory processing, adaptive behavior, and social interaction in individuals with autism.
- Trial name
- NCT06996795
- Testing
- music therapy, sensory integration
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Cowden's Disease, Cowden's Syndrome
Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations
The goal of this study is to examine the safety and treatment effects of everolimus in adults and children with PTEN Hamartoma Tumor Syndrome (PHTS) who experience social difficulties.
- Conditions
- Cowden's Disease, Cowden's Syndrome, Lhermitte-Duclos Disease, Cerebellum Dysplastic Gangliocytoma
- Trial name
- NCT07218575
- Testing
- Everolimus blinded oral capsules
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boston Children's Hospital
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