Clinical trials: Development
Autistic Disorder
Extended Management and Measurement of Autism
This open-label research study will continue to monitor the safety of fluoxetine in children after their completion of a previous double-blind placebo controlled clinical study, with fluoxetine.
- Trial name
- EMMA (NCT00787111)
- Testing
- Fluoxetine (prozac)
- Where
- 13 sites in United States
- Volunteers
- 128 people
- Sponsor
- Neuropharm
Nutrition Disorder, Child, Gross Motor Development Delay
Effect of a Nutritional Support System for Improving Gross Motor Function in Cerebral Palsy
Background: Most patients with cerebral palsy (CP) are dependent on parents due to the spasticity and limitations in their gross motor function.
- Conditions
- Nutrition Disorder, Child, Gross Motor Development Delay, Neuro: Cerebral Palsy, Diet Modification
- Trial name
- ENSSIGMCP (NCT03933709)
- Testing
- Nutritional Support System (NSS), deworming, recommended diet
- Volunteers
- 30 people
- Sponsor
- Anahuac University
Elopement, Autism Spectrum Disorder
A Study of the Elopement Prevention and Safety Training Program
The purpose of this study is to demonstrate the feasibility of the Elopement Prevention Safety (EPST) program in children with autism spectrum disorder (ASD) who have engaged in eloping.
- Trial name
- NCT02383732
- Testing
- Universal Safety Measures Module (All participants), Proximity Training Module (Bolting Prevention Participants), Check-In Training Module (Wandering Prevention Participants)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Healthy, Hypertrophic Cardiomyopathy
Investigation Into the Use of Ultrasound Technique in the Evaluation of Heart Disease
The human heart is divided into four chambers. One of the four chambers, the left ventricle, is the chamber mainly responsible for pumping blood out of the heart into the circulation.
- Conditions
- Healthy, Hypertrophic Cardiomyopathy, Left Ventricular Hypertrophy
- Trial name
- NCT00001632
- Where
- United States
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Adolescents, Athletes
PLAYwithHEART: PLAY With Happiness, Engagement, Acceptance, and Respect With Your Team
This investigation aims to apply and test the feasibility of a structured Program for young athletes. PLAYwithHEART is a program for promoting acceptance and cooperation skills in adolescent athletes.
- Trial name
- NCT04850872
- Testing
- PLAYwithHEART Programme for adolescent athletes
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- University of Coimbra
Autism
Study to Evaluate the Efficacy and Safety of Aripiprazole
To evaluate the efficacy of flexibly dosed aripiprazole in reducing serious behavioral problems in Asian children and adolescents with a diagnosis of autism spectrum disorder, as measured by change from baseline to endpoint on…
- Trial name
- NCT02069977
- Testing
- Aripiprazole
- Where
- 6 sites in Philippines, South Korea and 1 more
- Volunteers
- 79 people
- Sponsor
- Yoo-Sook Joung
Motor Skills Disorders, Premature Birth
Premie DCD Imaging Intervention Study
This study will leverage a current longitudinal study of brain development in preterm children. In the Miller/Grunau Trajectories study, preterm children are returning for follow-up at 8-9 years.
- Trial name
- NCT04483401
- Testing
- Cognitive Orientation to Occupational Performance (CO-OP)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Child Development Disorder, Post Partum Depression
Optimization of Mother-child Dyad Follow-up by a Multidomain Application: Real-world Cross Sectional Study
After birth, the mother-child dyad can be impacted by issues which are usually under-detected or detected at early stage. Among these issues, neurodevelopmental disorders (NDD) such as autism spectrum disorder are common and…
- Trial name
- MALO_2 (NCT05215028)
- Testing
- web-application
- Where
- France
- Volunteers
- 4,346 people
- Sponsor
- Weprom
Tobacco Use Disorder, Smoking Cessation
Mobile Health (mHealth) Application for Smoking Cessation Among Adolescents in Indonesia
This mixed-methods study develops and evaluates a mobile health (mHealth) application for smoking cessation among Indonesian adolescents aged 13-15 years.
- Conditions
- Tobacco Use Disorder, Smoking Cessation, Adolescent Smoking
- Trial name
- NCT07198828
- Testing
- mHealth Smoking Cessation Application, Paper-based Control Materials
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Pit and Fissure Sealants, Molar Incisor Hypomineralization
Clinical Evaluation of Two Different Pit and Fissure Sealants
It is planned to include girls and boys between the ages of 6-12 who apply to Başkent University Faculty of Dentistry, Pediatric Dentistry Clinic for routine dental examination.
- Trial name
- NCT06776471
- Testing
- Resin-based flowable filling material
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Baskent University
Autism Spectrum Disorder
Promoting Transactional Supports to Optimize Social Communication Outcomes for Infants and Their Families
This early treatment project is designed to address two significant public health challenges - the need for validated, manualized, treatments for young children with Autism Spectrum Disorder (ASD) that are cost-efficient and…
- Trial name
- NCT03307057
- Testing
- Social Communication Growth Charts (SCGC), Parent-Implemented (P-I) Condition, Clinician-Implemented (C-I) Condition
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- Emory University
Growth and Development
A Study to Investigate the Impact of Fortified Malt Based on Immunity Outcomes in School Children
This study will test the hypothesis that a fortified malt based food may improve immunity outcomes in 7-10 year old school age children.
- Trial name
- NCT02542865
- Testing
- Fortified malt based food
- Where
- India
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Duchenne Muscular Dystrophy (DMD)
DMD and Gamified Physiotherapy
Duchenne Muscular Dystrophy (DMD) is a progressive neuromuscular disease that limits children's physical function, mobility, and participation in daily life.
- Trial name
- Gamified DMD (NCT07368400)
- Testing
- Gamified Mobile Physiotherapy Exercise Application, Standard Home Exercise Instructions
- Volunteers
- 46 people
- Sponsor
- Başak Çağla Arslan
Cognitive Impairment, Child Autism
Exercise and Cognition in Children With ASD
Physical exercise is widely reported to be beneficial to executive functions (EFs) in children with autism spectrum disorder (ASD).
- Trial name
- NCT05503459
- Testing
- Bicycle learning, Stationary cycling
- Where
- Hong Kong
- Volunteers
- 82 people
- Sponsor
- Education University of Hong Kong
Autism
To Share or Not To Share: Navigating Disclosure and Stigma Among Family Caregivers of Autistic Young Adults_Group Intervention
This study is a caregiver support program for family caregivers of autistic young adults (ages 18 to 26) as their family members navigate young adulthood.
- Trial name
- NCT07856927
- Testing
- Group Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Autism
Randomized Study of Fluoxetine in Children and Adolescents With Autism
OBJECTIVES: I. Evaluate the efficacy of fluoxetine on social and language deficits, global severity and compulsive dimensions of children and adolescents with autism. II.
- Trial name
- NCT00004486
- Testing
- fluoxetine
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Scoliosis Idiopathic Adolescent
Lung Regeneration After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) is a curvature of the spine that occurs in 1-2% of otherwise healthy children, and requires corrective surgery, posterior spinal fusion (PSF) in ~10% of cases.
- Trial name
- NCT03539770
- Testing
- Posterior spinal fusion
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Succinic Semialdehyde Dehydrogenase Deficiency, SSADH Deficiency
PET Imaging of GABA Receptors in Succinic Semialdehyde Dehydrogenase Deficiency
This study will use brain imaging to map brain cell receptors for a chemical called GABA, a chemical that inhibits the activities of nerve cells.
- Trial name
- NCT00246870
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics (PK), and pharmacodynamics (PD) of atumelnant treatment in pediatric participants with classic congenital adrenal hyperplasia (CAH).
- Trial name
- NCT07159841
- Testing
- Atumelnant
- Where
- 51 sites in United States, Argentina and 11 more
- Volunteers
- 153 people
- Sponsor
- Crinetics Pharmaceuticals Inc.
Infertility and at High Risk of OHSS
Repeated Injection of GnRH Agonist to Reduce Ovarian Hyperstimulation Syndrome
Gonadotropin releasing hormone (GnRH) agonist is sufficient for triggering final oocyte maturation in GnRH antagonist protocol and can significantly reduce incidence of ovarian hyperstimulation syndrome (OHSS) in high-risk…
- Trial name
- NCT02022241
- Testing
- triptorelin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chenshiling