Clinical trials: Development
Molar Incisor Hypomineralization
Use of a Glass Ionomer Sealant in Molar Incisor Hypomineralization
Molar Incisor Hypomineralization (MIH) is a worldwide widespread qualitative developmental defect of the dental enamel with a multifactorial aetiology defined in 2001 as an "hypomineralization of systemic origin affecting one or…
- Trial name
- NCT05806398
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Burlo Garofolo
Transient Hypothyroxinemia of Prematurity (THOP)
Study of Thyroid Hormones in Prematures
The investigators hypothesize that continuous infusion of 4 µg/Kg/day T4 with 30 µg/Kg/day oral potassium iodide (KI) for 42 days from birth will reduce by 30% or more (from an estimated 30% to 21%) the proportion of extremely…
- Trial name
- THOP2 (NCT02103998)
- Testing
- thryoid hormone T4 + oral potassium iodide (KI) for 42 days, D5W - 5% dextrose water
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- New York Medical College
Asthma in Children
The Role of Biomarkers in the Occurrence and Development of Asthma
To study the expression level of biomarkers such as GITRL in peripheral blood of children with asthma and analyze their correlation with the severity of asthma.
- Trial name
- NCT05768399
- Testing
- The level of biomarkers in Peripheral blood
- Where
- China
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Chongqing Medical University
Nutrition Disorder, Child, Nutrition Disorders in Adolescence
Health and Nutrition Survey on Shenzhen Children
1. Master and analyze the nutritional health, growth and development status of primary and secondary school students in Shenzhen, and discover the main nutritional health, growth and development problems and influencing factors.
- Conditions
- Nutrition Disorder, Child, Nutrition Disorders in Adolescence, Nutritional Deficiency, Nutrition, Healthy
- Trial name
- NCT05244785
- Where
- China
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty
YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition
More children will survive to adulthood today than at any other point in human history, as evidenced by the proportion of live births and absolute numbers.
- Conditions
- Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty, Malnutrition, Child, Gestational Diabetes
- Trial name
- YUVAAN (NCT05603793)
- Testing
- Knowledge, Attitude & Practices
- Where
- India
- Volunteers
- 1,304 people, healthy volunteers welcome
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute
Bipolar Disorder, Attention Deficit Disorder With Hyperactivity
Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls
The purpose of this research is to learn more about how children with mental health problems, including bipolar disorder (BD), attention deficit hyperactivity disorder (ADHD), and generalized anxiety disorder (GAD), differ from…
- Conditions
- Bipolar Disorder, Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder Without Hyperactivity, Generalized Anxiety Disorder
- Trial name
- BBPP (NCT01570426)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Bradley Hospital
Cerebral Palsy
Cerebral Palsy Early Mobility Training
The purpose of this study is to determine the optimal treatment duration of a novel early mobility training program (dynamic supported mobility, DSM) between 6 to 24 weeks of treatment; and to evaluate the clinical futility of…
- Trial name
- iMOVE (NCT02340026)
- Testing
- Dynamic Supported Mobility, Conventional Therapy
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital of Philadelphia
Autism, Autistic Disorder
Early Characteristics of Autism
This study will identify factors that distinguish children with autism from children with developmental delay and those with normal development and study the efficacy of intensive behavioral therapy in children with autism.
- Trial name
- NCT00090415
- Testing
- Intensive behavioral therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Washington
Relation, Mother-Child, Family Conflict
Children's Learning Centers Group FNI
The purpose of this study is to compare the effects of Family Nurture Intervention in a mother-child group setting with a Standard Children's Learning Center (CLC) Program for preschool-aged children (ages 2-4.5).
- Conditions
- Relation, Mother-Child, Family Conflict, Emotional Disturbances, Behavior Problem
- Trial name
- NCT03908268
- Testing
- Family Nurture Intervention (FNI), Standard Children's Learning Center (CLC) Program
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Columbia University
Developmental Dysplasia of the Hip
Automatic Characterization of the Neonatal Hip Using Ultrasound Imaging
Ultrasound imaging (US), a radiation-free imaging modality, is currently used in diagnosis of developmental dysplasia of the hip (DDH) in infants.
- Trial name
- NCT02796768
- Testing
- 3D US Scanning, 2D US Scanning
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- British Columbia Children's Hospital
Premature Infant Disease
A Randomized Controlled Trial to Evaluate the Effect of White Noises and Parental Voices As Protectors Against Noise Damage in a Neonatal Intensive Care Unit
The goal of this Randomized Controlled Trial is to test the efficacy of listening to white noises and parental voices against environmental noise damage in premature babies admitted to the Newborn Intensive Care Unit.
- Trial name
- NCT06150404
- Testing
- White Noises and Maternal and/or Paternal voices
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- Istituto Giannina Gaslini
Type 1 Diabetes
Applying the "New Authority" Model in the Treatment of Poorly Controlled Diabetic Adolescents and Their Families
It is presumed that families of poorly controlled diabetic adolescents (type 1) would benefit from parents' counselling, guided by "the New Authority" model.
- Trial name
- NCT02093676
- Testing
- experimental protocol treatment "The New Authority"
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Cytomegalovirus Infections, HIV Infections
A Study of HIV and Cytomegalovirus (CMV) in HIV-Infected Patients
To define relationships between 1) HIV load and risk of CMV disease, 2) CMV load and the risk of developing CMV disease, and 3) CMV load and HIV load.
- Trial name
- NCT00001089
- Where
- 36 sites in United States
- Volunteers
- 400 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma, Allergic Rhinitis
RAPP-children, Rhinitis & Asthma in Patient Perspective: Development and Validation of a Questionnaire for Quality of Life Evaluation in Children With Asthma and Allergic Rhinitis
This observational study aims at developing and validating a simple questionnaire to be routinely applied in the clinical practice, for the evaluation of the quality of life in children with concomitant asthma and allergic…
- Trial name
- RAPP (NCT03276416)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder
PEERS® for Italy, a Study on Social Skills Intervention for Adolescents With Autism Spectrum Disorder (ASD).
TThe research aims to verify the Italian adaptation of a parent-mediated group training focused on social skills for adolescents with autism spectrum disorder (ASD).
- Trial name
- NCT05473104
- Testing
- Program for the Education and Enrichment of Relational Skills
- Where
- Italy
- Volunteers
- 37 people
- Sponsor
- Istituto Superiore di Sanità
Development Coordination Disorder
Characteristic of Play: Comparison Between Children With Development Coordination Disorder ( DCD) and Children With Typical Development
There will be found differences in the issue of characteristic of play between Children with Development Coordination Disorder and Children with Typical Development.
- Trial name
- NCT01130038
- Where
- Israel
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Autism Spectrum Disorders
Parent-supported Social Skills Training for Teens With Autism Spectrum Disorders (PEERS-K)
This study aims to develop a parent-assisted social skills training program for adolescents with autism spectrum disorder(ASD) and verify therapeutic effects of the program through case-control study. 1.
- Trial name
- NCT01501058
- Testing
- parent-assisted social skills training program for adolescents with autism spectrum disorder, Delayed intervention
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Autism
Neuropsychopathological Study of Autism
Autism or autism spectrum disorder (ASD) is a relatively common (0.3% in Taiwan), multi-factorial, genetically and clinically heterogeneous, childhood-onset neurodevelopmental disorder.
- Trial name
- NCT01677663
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Mother to Child Transmission, Pregnancy in Adolescence
Digital Intervention to Address Stigma Among Pregnant Adolescents Living With HIV
Pregnant adolescents living with HIV (ALHIV) in Kenya frequently experience stigma and difficulty telling a family member about their HIV and pregnancy status.
- Conditions
- Mother to Child Transmission, Pregnancy in Adolescence, Social Stigma, Self Disclosure
- Trial name
- NCT05383755
- Testing
- Digital intervention for pregnant adolescents living with HIV
- Where
- Kenya
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Pectus Excavatum
Comparative Analysis Of Modified Vs. Classical Nuss Technique In The Surgical Correction Of Pectus Excavatum "
Although the NUSS technique has become the standard minimally invasive procedure for correcting this deformity, there is a lack of comparative data between the classic and modified NUSS techniques.
- Trial name
- PE (NCT07312448)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France