Clinical trials: Development Delay
Child Language, Language Delay
Talk With Me Baby: Leveraging Well-Child Care to Enhance the Early Home Language Environment
Language-rich interactions with a parent or caregiver can serve as a protective factor for young children, by supporting their language development and other positive long-term outcomes, but existing interventions have not had…
- Conditions
- Child Language, Language Delay, Developmental Milestones
- Trial name
- TWMB (NCT07132411)
- Testing
- Patients in Talk With Me Baby Clinics, Patients in Care-As-Usual Clinics
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Kansas Medical Center
Children With Developmental Delay
Joint Planning in Paediatric Rehabilitation
We will use one group, pretest-posttest research design. The intervention will have a 6-month timeframe. Up to 18 participants will be selected from active caseloads of the three to six participating healthcare providers in the…
- Trial name
- NCT04385706
- Testing
- Applied Coaching Model
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Western University, Canada
Autism Spectrum Disorder
Headsprout Reading Program in Children With Autism Spectrum Disorder and Reading Delay
Headsprout is a commercially available computer-based reading program that teaches children fundamental reading skills, including phonics, fluency, and comprehension.
- Trial name
- NCT03055533
- Testing
- Headsprout reading program
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Nebraska
Developmental Delay (Disorder)
Creative Music Therapy for Premature Infants
This study investigates whether creative music therapy applied to premature infants will facilitate brain growth and development at term equivalent assessed by magnetic resonance imaging.
- Trial name
- NCT02434224
- Testing
- Music Therapy
- Where
- Switzerland
- Volunteers
- 81 people
- Sponsor
- University of Zurich
Mental Retardation, Developmental Delay Disorder
Atypical Neuroleptic Drugs in People With Mental Retardation/Developmental Delay
Psychiatric drugs are often used to treat behavioral symptoms of mental retardation/developmental delay (MR/DD). These drugs can cause serious side effects. Newer drugs may have decreased side effects.
- Trial name
- NCT00065273
- Testing
- risperidone, clozapine, olanzapine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Brain Developmental Diseases, Autism Spectrum Disorder
The Early Integrated Intervention for Child Brain-developmental Disorders in China
This study is focused on developing the early integrated intervention for child brain-developmental disorders, including globe developmental delay (GDD), autism spectrum disorder (ASD), and attention deficit-hyperactivity…
- Conditions
- Brain Developmental Diseases, Autism Spectrum Disorder, Global Developmental Delay, Attention Deficit-Hyperactivity Disorder
- Trial name
- NCT03847402
- Testing
- The early integrated intervention for GDD, The early integrated intervention for ASD, The early integrated intervention for ADHD
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Children's Hospital of Fudan University
Ankyloglossia, Speech Delay
Frenuloplasty for Speech and Myofunctional Outcomes
Children with ankyloglossia (tongue tie) can have abnormal tongue function, putting them at a disadvantage when it comes to speech and articulation.
- Conditions
- Ankyloglossia, Speech Delay, Dentofacial Abnormalities
- Trial name
- NCT06089629
- Testing
- Lingual frenuloplasty
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Oregon Clinic
Autism Spectrum Disorder, Developmental Delay
Improving Autism Screening With Brain-Related miRNA
The goal of this project is to identify specific miRNAs that are increased or decreased in the saliva of children with developmental delay and are useful for screening toddlers for ASD.
- Trial name
- NCT02712853
- Testing
- Saliva collection, Vineland Adaptive Behavior Scale-II Assessment
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Pediatric Obesity
Developmental Trajectories of Reinforcer Pathology and Childhood Obesity
The goal of this observational study is to understand how children's food preferences, physical activity, and decision-making change over time and how these behaviors relate to body weight and overall health.
- Trial name
- TRACK (NCT07229508)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Development Delay, Development, Child
The Opening Doors to Early Intervention Study
Poor urban minority children often experience delays in their early development leading to health disparities. Publicly funded early intervention services are available to improve child development among these children in…
- Trial name
- ODEI (NCT03625115)
- Testing
- Family Navigator (FN)
- Where
- United States
- Volunteers
- 357 people
- Sponsor
- Children's Hospital of Philadelphia
Premature Baby, Neurocognition, Child
Longitudinal Assessment of Early Premature Infant Skills for Audiovisual Speech Perception
From birth, babies perceive speech face to face with their interlocutors in audiovisual situations (AV): in addition to hearing them (auditory speech), they will also, in most cases, be able to observe their speaking faces (ex…
- Trial name
- Pré-AV (NCT07245693)
- Testing
- Audiovisual association capability tests
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Obesity, Blood Pressure
Upstate New York Infant Development Screening Program
The goal of the Upstate KIDS Study is to track the growth, development and long-term health of children given the increasing use of infertility treatment, occurrence of maternal obesity and pregnancy complications, and rising…
- Conditions
- Obesity, Blood Pressure, Motor Delay, Developmental Delay
- Trial name
- Upstate KIDS (NCT03106493)
- Testing
- None (observational)
- Volunteers
- 6,171 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Growth & Development, Obesity
Effects of Infant Egg Consumption on Child Health and Cognition Development
The objective of this study is to examine how infant egg consumption (age of introduction and frequency of intake) influences physical growth, obesity, cardio-metabolic health, risk of food allergy, and cognition development in…
- Conditions
- Growth & Development, Obesity, Cardiovascular Risk Factor, Metabolic Syndrome
- Trial name
- NCT04345185
- Testing
- Infant egg consumption (i.e., age of introduction and frequency of intake)
- Where
- United States
- Volunteers
- 5,374 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Cognitive Developmental Delay
Neurocognitive Follow-Up (FU) Study
This is a follow-up study of a recently completed trial (17.14.INF) evaluating the growth of pre-term infants. Enrolled children will undergo neurocognitive assessments at 18- and 24-months of corrected age (CA).
- Trial name
- NCT04962035
- Testing
- Neurocognitive Follow-up
- Where
- 3 sites in Poland, Slovakia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Developmental Delay
Responsiveness of the Object Permanence Scale
The aim of the study is the examining responsiveness of the Object Permanence Scale. The sample of the study will be 7-16 months old babies with motor developmental delay.
- Trial name
- NCT05749783
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Tokat Gaziosmanpasa University
Dementia, Cognitive Decline
Ammonia Levels and Cognitive Impairment
The purpose and objective of this study is to determine the prevalence of elevated ammonia levels in subjects with cognitive impairment, and to observe if treating the cause of the elevated ammonia level improves mental status.
- Conditions
- Dementia, Cognitive Decline, Cognitive Impairment, Developmental Delay
- Trial name
- NCT02059356
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Duke University
Preterm Birth, Low Birthweight Neonate
Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial
The ground-breaking Prevention of Prematurity and Xylitol (PPaX) cluster randomized controlled clinical trial was conducted in Lilongwe, Malawi and enrolled approximately 10,069 pregnant individuals seeking to evaluate the impact…
- Conditions
- Preterm Birth, Low Birthweight Neonate, Periodontitis, Gingivitis
- Trial name
- XaPPP (NCT07424846)
- Testing
- Xylitol Chewing gum, Sorbitol chewing gum
- Where
- Malawi
- Volunteers
- 6,000 people
- Sponsor
- University of Washington
Bilateral Sensorineural Hearing Loss, Speech and Language Development Delay Due to Hearing Loss
Neural Prediction to Enhance Language
The language outcome of children receiving cochlear implantation to address bilateral sensorineural hearing loss is more variable than that of typical hearing children.
- Conditions
- Bilateral Sensorineural Hearing Loss, Speech and Language Development Delay Due to Hearing Loss, Social Communication
- Trial name
- NCT05962359
- Testing
- Parent-Implemented Communication Treatment
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Cerebral Palsy, Myelomeningocele
Ready, Set, Go! A Physical Fitness Intervention for Children With Mobility Challenges
Barriers to keeping and maintaining fitness as a young person with a disability exist across many domains of access to community locations such as fitness centers, so looking outside of these establishments may be necessary to…
- Conditions
- Cerebral Palsy, Myelomeningocele, Arthrogryposis, Motor Skills Disorders
- Trial name
- NCT04789746
- Testing
- adapted Chicago Run running program
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Northwestern University
Neurodevelopmental Abnormality
Two Year Developmental Follow-up for PREMOD2 Trial (Premature Infants Receiving Milking or Delayed Cord Clamping)
An extension of the PREMOD2 trial, the PREMOD2 Follow-Up trial will evaluate the neurodevelopmental outcomes at 22-26 months corrected age of preterm children who received UCM or DCC.
- Trial name
- PREMOD2FU (NCT03476980)
- Testing
- Randomized to Umbilical Cord Milking at birth, Randomized to Delayed Cord Clamping at birth
- Where
- 18 sites in United States, Canada and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Sharp HealthCare